KEGG   Rana temporaria (common frog): 120945261
Entry
120945261         CDS       T07929                                 
Symbol
WNK2
Name
(RefSeq) serine/threonine-protein kinase WNK2 isoform X1
  KO
K08867  WNK lysine deficient protein kinase [EC:2.7.11.1]
Organism
rtem  Rana temporaria (common frog)
Brite
KEGG Orthology (KO) [BR:rtem00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rtem01001]
    120945261 (WNK2)
   01009 Protein phosphatases and associated proteins [BR:rtem01009]
    120945261 (WNK2)
Enzymes [BR:rtem01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     120945261 (WNK2)
Protein kinases [BR:rtem01001]
 Serine/threonine kinases: Other
  Wnk family
   120945261 (WNK2)
Protein phosphatases and associated proteins [BR:rtem01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     120945261 (WNK2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr CCTL2_WNK OSR1_C
Other DBs
NCBI-GeneID: 120945261
NCBI-ProteinID: XP_040215226
LinkDB
Position
7:44245235..44557296
AA seq 2171 aa
MDHASNRAGACDSQSTTRNLIESGVHTKKAQGLKSECPAKPNDRTRSPINIHELNSSGNI
MDTAMLNSVKDAQLMPAPKDLRTVKLRFLRRTVVESDQEEPSVLDLSESLHQSKVIPISR
TRRAIAKRAQGTSDQGSTTETSEPKTADSIEHIAEVPPEPTGQKRKDEPDTLKEAPKSKK
EEEEETEEEADMKAVSTSPDGRFLKFDIEIGRGSFKTVYKGLDTETWVEVAWCELQDRKL
TKVERQRFKEEAEMLKGLQHPNIVRFYDFWESCLKGKKCIVLVTELMTSGTLKTYLKRFK
VMKPKVLRSWCRQILKGLHFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRA
SFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTS
GVKPASFEKVSDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDNGRK
STIALRLWVEDPKKLKGKPKDNGAIEFTFELEKETPEDVAQEMIESGFFNESDVKIVAKS
IRDRVALIQWRRERIRPENGDTEVMEQMNVPQIPLPPLAHSSHIGQHEGEELETDQHLFL
PKLPASITSVASDSTFDSGQGSTVYSDSQSSQQSVIYSSLPDALPSAIQRVFSPPMIEGQ
VLPQSPQHQLGQYQQPAAHGVGVIPAVHSGLTQHQYQELSTAYPVVQPSTVSSAQFGASP
PILSSQQSLQHQSLLQQIPAGQAVCPVPPTSHTYPQYQPPLTPAPLQIPTVPLQQHQVPA
SQLPPYPLIPAVTPLTGLESLPANLSDLPTVCITPLPAPCQYFPPGVVMPNLPVTPAGPP
SGQTVKPQLVLQYETNLVPNIQGAPVSLLAVATSGMPGIPMPLPQHPQSHTYQASFQQII
QSDVPSVHLSPSVPPVSQQSHLPLPPQSHHPSIIHPPDQTTSGAGNQVIGLSQYKVDFTT
PVGVLPVVTMMSPPVHFPSEISQPLLGQDYLAQPSLPLTMPHSEAVLAENQSMSYPSTGI
SQAPESHNLTQCQARQSFAESAHEEQHNQENLPSSNQSFDNYIGSDAASGREMSDGYEGI
PGGKPDGKPAKKHHRRSSRTRSRQEKTNKPKLTILNVCNTGDKMVECQLETHNHKMVTFK
FDLDGDAPEEIATYMVENEFILQMEKEIFIEQMKDVIDKAEDMLSEDTEGERSSDQGASP
QQADSFKAEMREENQHTPIRTPVYQQNVLHTGKRWFIICPVMESPSSTDVSSVTTKTEHQ
SDSTGGNAKDEKACEDGQHKFSTEQDKSNSTASQSISTDVDVEIPASLTLSSITQSSSTI
FSDLQTQTEMSFSPHPELLSFRQGDSATLGASAGFQQVVELEEAESRVLSLNEKPTAHTL
AQTEHNKCVSPSDRRYNAVGSNELVHPAQATHDNGKPHHPPQENAASLQPEQQVLYESEC
SPPVVQVTADTGLAVNSNQRNEPLHIQEVSAASQPVLQTQAQPLALPLVNSTVQQANMES
DGEGPPRVEYTDDTIKTLDEKLRNLLYQEYAPTNQSAGTPEYSVTMENIAEVIRSQPLNA
DIISMTGCNRTILDLIESAPSAESVSGDTSGHESPRHWIHTAASSQRRYSGDQKVKEGSS
SPKKRHHHAEKSKTIGRFSVLSTEDEVTVTFPCYQRFSAPPDVYLDQLPTNLVKTSVPRA
HTSSPINSLFCGHVSSDSGDEIFQRKAKDSAPSTPSKGANDFMKKAAAFLHRKSSVQSPD
SPSGQGMKIPSINVTSFHSQSSYVSSDNDSEFEDADMKKELQNLREKHMKEITELQVQQR
REIESLYVRLGKPLPPNVGFLHAAPPSGRRRRVSKNKLKSGKLLNPLVQQLKNGASNITA
DCNGLPAKDPLKSHLDLKGNVSGSALTASPGRNVQTQQPCSVKVTVSSDNICSGVVRDGG
DVHGNGGQGWTVYHQTSERVTYKSSSKPRTRFLSGPVSLSIWSTLKRLCLGKEHSNRSST
SSLVTGPEPSQVPSLNTQQVQAQSNNSNNKKGTFTDDLHKLVDEWASKTVGAAQFKPSLN
QLKQYQQRLDLEHKPTTAHEDSNAGGQPIPEPARKYNAPLSCSATAGQMSTSLPAALSGA
TQSGILPPYMMPLCQYAGVFPAPVYGAQWPGAAAPAIAGSRLITQSASMQIFPMSLQQPT
VKQSGSNLRIT
NT seq 6516 nt   +upstreamnt  +downstreamnt
atggaccatgcatctaacagagcaggggcatgtgattcacaatctacaactagaaatcta
attgaaagtggggtgcatacaaaaaaggctcaagggctcaaaagtgagtgtcctgcaaaa
cccaatgaccgtactcggagtcctataaatattcatgaactgaacagcagtgggaatatc
atggacactgcaatgctgaactcggtgaaagatgcccagcttatgccagctcctaaagac
ttgagaacggtcaagctgaggttcttgaggaggaccgtggtagagtcagatcaagaggag
ccatcggttttggatctgagtgaatctctgcaccagagcaaggtcatccccatctctaga
accagaagggccattgctaagagggcacaggggacaagtgaccaaggatccaccaccgag
accagcgagcctaagactgcggattccatagagcatatcgcagaagtaccaccagaacca
actggccaaaagcgaaaagatgaaccggacactcttaaagaagcaccaaagtccaaaaag
gaggaggaagaggagactgaagaggaggcagatatgaaagctgtttctacttcccctgat
ggaaggtttttgaagtttgacattgagattggaagaggctcctttaaaactgtttataag
ggtctggatacagaaacatgggtggaggtcgcatggtgcgaacttcaggaccgtaaatta
acaaaagttgagagacagagatttaaagaggaggcggaaatgttaaaaggtttgcaacat
ccaaacattgtgagattttacgacttctgggaatcctgcctgaagggaaagaaatgcatt
gtcttggtgaccgagctcatgacatcagggacactgaaaacatacttgaaacgatttaag
gtcatgaagccaaaggttttgcgcagctggtgtcggcaaattcttaaaggcttgcacttt
cttcatacacgaactcctccaataatccatcgggacttaaaatgtgataacatttttatt
acggggccaactggctctgtgaagattggagatctgggcctggctaccttgaaacgagcc
tcttttgctaaaagtgttataggaaccccagagtttatggcacctgaaatgtatgaagaa
cattatgatgaatctgtggatgtatatgcttttggaatgtgcatgttggaaatggctacc
tcagaatacccatactctgaatgccagaatgctgctcaaatataccgcaaagtcaccagt
ggggtgaaaccagccagctttgagaaagtgtcagaccctgaaatcaaagagataattggg
gaatgcatttgtaagaacaaggaggagaggtatgaaattaaagacttactaagccatgct
ttctttgctgaagacacgggggtaagggtggaattggctgaggaagacaacggcagaaaa
tccacgattgccttaagactatgggtagaagaccccaagaaattgaaaggaaaacccaaa
gataatggagccattgagtttacctttgagctggaaaaggaaactccagaggatgttgcc
caggaaatgattgagtctggatttttcaatgaaagtgatgtgaagatagttgcaaagtca
atacgtgatcgagtggcattaatccaatggagacgagagagaattaggccagagaatggt
gatacggaggtgatggaacagatgaacgtaccccagattccccttccaccacttgcccac
tcttcccacataggtcaacatgaaggagaagaattggagacagaccagcacttatttttg
cccaaactgcctgccagcattacttctgtagcatctgacagcacatttgacagtggtcaa
gggtctacggtgtactccgattcacagagcagtcaacaaagtgtcatttactcttccctg
ccagatgctctaccttcagccatccaacgagtattcagcccacctatgattgagggccag
gttcttccacagagtcctcagcatcaactagggcaataccagcagcctgcagcacatgga
gttggtgttatacctgctgtacactctggactcactcagcatcaataccaagaactgagc
acagcctacccagttgtgcagccatccaccgtctcgtctgcccagtttggggcttctcct
cctatattatccagccagcaatcacttcaacaccaatctcttctacaacaaatcccagct
gggcaggctgtctgtccagtgccacctacctcccatacatacccacagtaccagcccccg
ctcacgccggctccactacagattcctacagtaccactgcaacagcaccaggtacctgca
tcacagcttcctccgtatcctctcataccagcagttactcctcttacaggactcgagagc
ctccctgccaatctctctgacttacctactgtctgtatcactcccctgcctgctccctgt
cagtatttccctccaggtgtggttatgcccaaccttcctgtcacccctgcagggcccccg
tcagggcagacagtcaaaccacagttggtgctacaatatgagactaatcttgtgccaaat
atccagggtgcgcctgtatctttattagcagtggcaacatctggcatgccaggaatacca
atgccgctgccacagcatccccagtcacacacgtaccaggcctcttttcagcagatcatt
cagagtgatgtcccttctgttcatctctctccaagtgttccgcccgtgtcacaacaatcc
catcttcctcttcctcctcagtcacatcatccaagcataatccatcctcccgatcagact
acatctggggctgggaaccaggtcattggtctttcccagtataaagtggacttcactacc
cctgtaggagtgttgccagttgtaacgatgatgtcgccaccagtgcacttcccctcagaa
atttcccaaccattgctaggacaagattaccttgctcaaccttctctaccacttaccatg
ccacattctgaggcagtcttggctgagaatcagagtatgtcctatccaagtactggcatt
tcccaggctcctgagtcgcataacctcactcagtgccaagcgagacagtcatttgcagaa
tctgctcatgaggagcagcacaatcaagaaaatctgccaagctcaaatcaaagctttgat
aattacataggttccgatgctgcctctggtagagaaatgagtgatggatacgagggtata
cctggcggtaaacctgatggaaagccagccaagaaacatcatcgaaggtcatcgcggact
cgctcccgccaggaaaagaccaataagcctaaactaactattcttaatgtgtgcaacact
ggagacaagatggtagaatgccagctggaaactcacaaccacaaaatggttactttcaaa
tttgacttggatggcgatgcaccagaggagattgctacatatatggtggaaaatgaattc
atactgcagatggagaaagagattttcattgagcagatgaaggatgtcatcgacaaggca
gaggacatgctgagcgaagacactgaaggcgagagaagctccgatcaaggggcaagtcct
caacaggctgactccttcaaggcagaaatgagggaggaaaatcaacataccccaataagg
acaccagtttaccagcaaaacgtcttgcatactgggaagcgttggtttatcatctgccca
gtgatggagagtccaagctctacagatgtctcttcagtaactacaaagaccgaacatcag
agtgacagcacgggtggtaatgccaaagatgaaaaggcctgtgaagatggtcaacataaa
ttttctacagaacaggacaagtccaactcaaccgcaagccagtcgatctcaacagatgtg
gatgtagaaattccagcttccttgacgctatcctctataacgcagtcatcctctactata
ttttctgatctgcaaactcagactgaaatgtcattttcacctcatccagaacttctttcc
ttccgacaaggagattctgctactcttggtgcatctgcgggttttcagcaagttgttgaa
ttggaagaagcagaatcccgtgtattgtctctgaatgagaagccaacagcccacacactg
gcacaaaccgagcacaataagtgtgtgtcaccatcagatcgaagatacaatgctgtaggg
tcaaatgaactggtccatcctgcacaggcaactcatgataacggtaaaccacaccaccct
cctcaggaaaacgctgcaagtcttcagcctgaacagcaggtgctctatgaatcagaatgc
agtccacctgttgtccaagtaacggcagacactggtttggctgtcaacagtaatcaaagg
aatgagccattgcacattcaagaagtatctgcagcatcccaacctgtcttacaaactcaa
gctcagcctttagctttaccattagtgaattcaactgtacaacaagctaacatggaatca
gatggagaaggtccaccaagagtggaatatactgatgataccattaagactttagatgaa
aagctccgtaatctgctatatcaggaatatgctccaactaatcagtctgctgggacacca
gaatattctgtgaccatggaaaatatagcagaggttatcagatcacagccactgaatgca
gacataatttctatgacaggttgtaacagaaccatcttggatctaattgagagtgctcca
tcagcagaatcagtcagtggtgacaccagtggccatgaatcgccaagacattggatccat
actgctgcttcatcacaaagacgctattctggagatcagaaggtgaaagagggaagttct
tctcccaaaaagagacatcatcatgctgaaaagtcaaaaacaattgggaggttttctgtt
ctgagtacagaagacgaggtgactgtcacatttccatgttatcagaggttttcagctcct
ccagatgtctatcttgaccaacttcccaccaatctagtcaagacttctgtgcctcgcgca
catacatcttctcctataaattctcttttctgtggacacgtgtcaagtgattcaggggat
gagatttttcaacgaaaggccaaagattctgctccatcaaccccaagcaaaggggccaat
gacttcatgaagaaagctgcagctttcctgcatcgaaagtctagtgtgcagagcccagat
tccccaagtggacaaggcatgaaaatcccttcaataaatgtgacatctttccattcacag
tcttcctatgtgagtagtgacaatgactcggagtttgaggatgctgatatgaagaaggaa
ttgcagaatctcagagaaaagcacatgaaagaaatcacagaattacaagtacagcagagg
agagagatagaatctctttacgtcaggctgggcaagcctcttcctcctaatgtgggattc
ctacatgcagcgccaccaagtggccgtcgacgcagggtcagcaagaataaactgaaaagt
ggaaagttacttaatcctttggttcagcagctgaaaaacggggcaagcaatataactgca
gactgcaatggattacctgccaaggatccacttaaatctcacctcgatttaaagggcaac
gtttctggctccgccctaacagcgtccccgggtcgtaatgtccagacgcagcagccttgc
tcagtgaaggtcacggtgtcgtctgataatatctgttctggtgtagtccgggatggtggt
gatgtgcatggcaacggtggacaaggctggacggtttaccatcaaacgtctgagagagtg
acctataagtctagtagcaaacctcgtacccgattcctcagtggacctgtgtctttatcc
atctggtctactctgaaacggctatgtctaggcaaagagcacagcaatagatcctcaaca
agtagccttgtaacaggccctgaaccatcacaagttccttcactgaacactcagcaagtt
caggcacagtctaacaatagtaacaacaaaaagggaacatttactgatgaccttcacaaa
ctggtggatgaatgggcaagcaaaactgttggagcagcacaattcaaaccttctcttaat
caactgaagcagtatcagcagcggctggacctggagcacaagcctacaactgcacatgaa
gattcaaatgcaggaggtcaacctattcctgagccagccagaaagtacaacgctccactg
tcttgttcagcaaccgcgggacagatgtccacatctctcccagcagccctttcaggagct
acccagtctggtatattaccaccatatatgatgcccctttgtcagtatgctggggttttc
ccagcaccagtttacggagcgcagtggcctggagcggcagcacctgccatagcaggaagt
cggttgatcacgcaatctgcaagcatgcagatatttcctatgtctttgcagcaacctacc
gtgaaacaatctggttccaacctgagaatcacgtag

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