Ruminococcus torques: RTO_06500
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Entry
RTO_06500 CDS
T02606
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
rto
Ruminococcus torques
Pathway
rto00300
Lysine biosynthesis
rto00550
Peptidoglycan biosynthesis
rto01100
Metabolic pathways
rto01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
rto00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
RTO_06500
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
RTO_06500
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
RTO_06500
Enzymes [BR:
rto01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
RTO_06500
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
TPP_enzyme_M
Motif
Other DBs
NCBI-ProteinID:
CBL25383
UniProt:
D4M2C1
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All DBs
Position
643545..644930
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AA seq
461 aa
AA seq
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MKHMTLSEIADACCGIYYGDPAFLDREVSSVAIDSRKVVKDTLFVAIKGVRVDGHSFIPQ
VMEAGALCSLSEQDLGDVDYPYIRVSSCTEALKDLAEHYRRSLDIKVVGITGSVGKTSTK
EMIASVLSEKYNVLKTEGNFNNEIGLPLTVFNIREEHEVAVLEMGISHFGDMKPLAKIAR
PDVCVITNIGYAHLENLGTRDGILKEKSSMTDYMNPKGSVIFNGDDDKLKSYTSRDGRTP
VYFGLTSSCPFHVENIERKGLKGTYAEFVTPTSRFHAHISIPGDHMIYNALAGVAVGYAL
GMDNEEIARGIEKLVPIAGRNNLIEAKHYTIIDDCYNANPASMKSSLDVLAYADTRKVAI
LGDMGELGADELAMHREVGAYAAFKNTDVLVCIGALSKDMAEAAKETVLATEKNMKVFHF
DTKEDFYQNMRQILKDNDTILIKASHFMEFPEIVKKLSEEA
NT seq
1386 nt
NT seq
+upstream
nt +downstream
nt
atgaaacatatgacattatctgaaatcgcagatgcctgctgcggaatttattacggtgat
cctgcattcttagaccgcgaggtctcaagtgttgcgatcgacagccgtaaagtagtaaaa
gatactcttttcgttgcgatcaaaggggttcgtgttgatggacacagttttatcccgcag
gtcatggaagcaggtgcactctgttctctctctgagcaggatcttggtgacgttgattat
ccttatatccgcgtttcatcctgtacagaagcattgaaagacttagctgaacactatcgc
cgttccctcgatatcaaagttgtaggtatcactggaagtgttggaaagacaagcacaaaa
gaaatgatcgcatctgtactttccgagaaatataatgtactgaaaaccgaaggaaacttc
aacaatgagattggacttcctctgaccgtattcaatatccgtgaggaacatgaagttgca
gttcttgagatgggaatcagccattttggagatatgaaaccgctggctaagattgcccgc
ccggatgtgtgcgtgatcactaatatcggatatgcacatcttgagaatcttggaacaaga
gacggaatcctaaaggaaaagagttccatgacagactacatgaatccgaaaggttctgtt
atcttcaacggggatgatgataagctgaaaagctacacttcccgtgatggaagaactcct
gtttacttcggtcttacctcttcctgtccgttccatgtggaaaatattgaacgtaaagga
ttaaaaggaacatacgctgagtttgttactccaacatcccgtttccatgcacatatttca
atcccgggagatcatatgatctacaacgccttagccggagttgctgtcggatatgcactt
ggcatggataatgaagagattgctcgcggaattgaaaagctcgttccaattgcaggacgt
aacaacctgattgaagcaaaacactacacgatcattgatgactgctacaatgccaacccg
gcatctatgaagtcctctcttgacgtacttgcatatgcagatacaagaaaggtcgctatt
cttggcgatatgggtgaacttggtgccgatgagcttgcgatgcaccgcgaagtcggagca
tatgcagcatttaaaaacactgatgttttagtctgcatcggagcactttccaaagatatg
gcagaagctgcgaaggaaactgttcttgcgacagagaagaacatgaaggttttccatttt
gacacaaaagaagacttttaccagaacatgagacagattctcaaagataatgatacaatt
ctgatcaaagcttcccatttcatggaattccctgagattgtgaagaaactgtcagaagaa
gcataa
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