Rhincodon typus (whale shark): 109933028 Help Entry 109933028         CDS       T06055                                  Symbol mdn1 Name (RefSeq) midasin   KO K14572   midasin Organism rtp  Rhincodon typus (whale shark) Pathway rtp03008   Ribosome biogenesis in eukaryotes Brite KEGG Orthology (KO) [BR:rtp00001]  09120 Genetic Information Processing   09122 Translation    03008 Ribosome biogenesis in eukaryotes     109933028 (mdn1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03009 Ribosome biogenesis [BR:rtp03009]     109933028 (mdn1) Ribosome biogenesis [BR:rtp03009]  Eukaryotic type   Pre-60S particles    Other pre-60S particles     109933028 (mdn1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AAA_5 AAA_lid_7 AAA_lid_5 AAA_3 AAA AAA_16 AAA_7 AAA_22 nSTAND3 TsaE ABC_tran AAA_14 Sigma54_activat Sigma54_activ_2 Rad17 AAA_29 AAA_6 Dynein_heavy AAA_18 AAA_28 Mg_chelatase PduV-EutP bpMoxR MDN1_4th DUF815 ATPase VWA PRK AAA_23 Motif Other DBs NCBI-GeneID:  109933028 NCBI-ProteinID:  XP_048453390 LinkDB All DBs Position 5:complement(35564188..35748286) Genome browser AA seq 5573 aa AA seqDB search MEDLEFQFSSLALIAKLNDKSGTELNKYLTKQIWNEQDRQCILSILAQLLLDKDCTLLIG RHLRPLLLDLLERNVRSIKGAVFNHDLHERLCVAMSKLIDISPDVISFALRYFKDSPPVF QRLFLESSDSSAVRYGRKRMKLRDLMSAAYRLLKENWIMFGKLWDWSVCIPLLRSHDTLV RWYTARCLAVVTNMNDEQKNHFFKKILTAEELTTFRLQLLEEALCLNVEKALILANSKTA LWQKTKQLKYTQGHIMSGDLSENVVAVCGVVLPQKQLIHQDQFIGQPLVLVASTYNYLQS LAMAVASQNAVLLEGPIGCGKTTLVEYLAALTGRQKPPDFLKVQLGDQTDSKMLLGMYRC ADVPGEFVWQPGSLTQAVTNGYWLLLEDIDHAPLDVISVLIPLLETGELLIPGHGDCIKA APGFQFFATRRLFSSSVGWYRQQSSHATLLDKLWTKIQLDSMNKAELKEVLLNRYPSLEI VIDRLLDIYCQLTGTKHQGSQVTMDGNHENKQPPVECETKTDDKDLCLEGRGLSLRDLLK WCERIIDHFDCTSSSTALHIFQEALDCFTAMMSKRGSRKKMAEIIGSKLNISKEKVEFFC RLCKPAVELSEVEVTVGRAVIPRRRSDVVLLQLETQTFSATRPSALLLEQLAVCLRKKEP VLLVGETGTGKTSTVQYLARITGHKLKVVNMNQQSDTADLLGGYKPVDRKLLMLPLREAF EELFIQTYSRKQNITFLGHIQTCCKQKRWQDLLRLMLHVYKTAINKELKSKEDKGWLKDK WELLGLRLTQAQQQMKRAESALIFAFVEGTLAQAVKKGEWILLDEINLASAETLECLSGL LERNTSSLVLLDRGDTEPIQRDPEFRLFACMNPATDVGKKNLPPGIRNRFTELYVEELED EGDLRILVSDYLKGLSVSKKTIQGIIEFYLSVRKEKNVKLMDGTGHRPHYSLRTLCRALK FAALNSCNNVQRSLYEGFCMSFLTQLDRVSHPIVEKLICCHIIGNNAKAILQQPIPEPKG GRSIQIEGYWIATGDKEPSVDKLYILTPSVKLNLRDLARVVAAGIHPVLIQGETSVGKTS LICWLAAATGNHCVRINNHEHTDIQEYIGCYTSDETGKLVFKEGVLINAMRMGHWIILDE LNLAPTDVLEALNRLLDDNRELFITETQEVVKAHPRFMLFATQNPPGLYGGRKMLSRAFR NRFVELHFDELPKAELEIILNKRSSLPPSYCAKLVKVMLELQSYRRGSSVFAGKHGFITL RELFRWAERYRLTEQLMPGYDWIRHIATDAYMLLAGRVRKEEEVTVIHRILEKEFKRKLV PEVMFSKDSLQKRMDQWPSLTSVMSDDFRHVVWTYGMRKLAILVGQGLRFREAVLIVGET GCGKTTVCQMFASLFNQKLHTVNCHLHLETSDFLGGLRPVRHSCSEEDGANPNRLFEWHD GPLVLAMKEDNMFLMDEISLADDSVLERLNSVLEDEQTLLLAEKGSAEDDTVELITAGNR FRILATMNPGGDFGKKELSPALRNRFTEIWCPPINSREDMLAIIQHNLSPGLSFHEQDHQ GEDIAELILDFIDWLKNQEFGRRCVLSIRDLLSWVEFMNVTTRKATADVVDLDEIGDFQL DPVTGFIHAACLTCIDGIGTGSAFSSPEATLAARKACLSFLLKKLSKVAKLTKHMWNMLN SYDQKRKRKVVWTESYFGIHPFYIPIVGAVGEKAAVTDYALNASTTAMNAQRLLRAMKLK RPILLEGSPGVGKTSLVAALAKASGNQLVRINLSEQTDVTDLFGTDLPVEGGKGGEFAWR DGPLLAALKAGHWIVLDELNLASQSVLEGLNSCFDHRAEIFIPELGRCFIVEHNRTKIFG CQNPYHQGGGRKGLPKSFLNRFTQVYVDQLSVKDMEYIADTMFPAIGKNIVSKMVQFNYK INQEVMVERKWGQKGGPWEFNLRDLFRWCHLMLVDQMPGCYDPGQHVALVYVDRMRSNAD RNHMFSIFEEIFSLEDVGIHSHPYTGSRKFHITPQQVQVGYSILSRNGFIIPMTNKQLSI LHHSLQPLESIMKCAQMGWMVILVGPVASGKTSLIQLLALLTGQNLRVMAMNSAVDTTEL LGGFEQVDITRPWQRLVGKVKDVVSAITRDVLLSMDSGPDDGVLLKFWNSFLLSHSCCLN EDCDSAISSDAVNKLENLLILLQRFNNKVNTLSPAEFSELISEFQHFKHRRSESLDGQNR GTFEWVDGMLVQALNSGDWLLLDNVNFCSPSVLDRLNALLEPGGVLTVSERGVIDGTTPT IVPHPNFRLFMTMDPAHGEISRAMRNRGIEIYVAGEHSADPLDKQDVKTLLHGLGFVGDQ MCTELMTLYSEVKEITAGTSYSISSLLHCAVLIVHQLKRGLSLAEAFHQACTQVFVLSQS SQTQQEQVRELVEKHKLKLMSCESWGDSLVSLGLWPDSIPSAVFTAEESMLSMVHRDGQV LAYCLNQLSLSNNRSRPLTLTDLELVLQSSNMDSLVFHDNKTAVQATDELSMIPAAIRLV MEKASNQDWLLRARWLCHAAKVYKHLPELVCAQLEAGAKALNAVYSSVLPTGMKEVVQQL QLDANESASVPLDSRWNQQHLDILLNSVAYSGLHCSKELQAQLHSIANRMALLMDREERG YMEKASLSSDAARKSGRQSALRVSVAFQKGMMSFDDLPHPVLAHLAAFFEAWDACIVQCI KSSFSNLEDDAFHEVLCSTLWRDRFWLVSDRVVTDTEGIALLSLHWHWMMKHLLKDHLCQ LTDFSQIPQEIHTISVNLQSHLASPSEMIASVKGLQKCLGRPLPFKVGSVVECVSKLKVM SSVLDVLKLRPKMMDATWKEQLYRIKTTATDWKVKRGLMLAWGLVIQANHVVGYDAGVLQ HVVDSQASAMTSQGLLNSSDSQSLKADPPQLDGACLNQLASRIQLWPVLEYLALLSKYKV VADLMDLSLVSSSARSKPDQSVVGAELRQLITFCLRFTPMAAQDLREFWYLAQVDELSPE ELKLLSSGLMMTTFGPFWSSSITTDPDYWLTWKPPAIIGDDMVPEDTIDKSLKGPGILCR AIQSKCFFEILANTNRSHSVSFGGIGMTMATHVTLGEWLERTRQLQDISSVLWTNMAVGS FAEFRFTDSRLQCTMLLKQLHAIKDFLPKELQEEYLQTCDQLAIEKTSIASHSIQSLLSS LAEQGLLPEDVVSLLVTCVRKFVGKEKDFRSLSEKAQRGCLWVNLGLLQIQIWTPQTMFD PAVKKLYKLNYIKEELQQLQSEWKSRNLSEQLLTGRELLQEGENRHCHPRIRFLQQRINL LKEQIAALSRKQAHRPSVPQYDYLFQDIHHYVNTIAQKSKVKSLLSRLLQPLQAKRPKPC QSVQLVLNEEAAWQQSHHQFRRRIAEEYCQYPDIVEPLLAAILQMQHGMRLLASEVHVSL NNKLVKQAGLTRLVTCLLAFPSISFSFPTYLAQADELCSKASLETLKGLNQLLRKSSSDE KSLAKEQRLLPTQEQLLMNALLYLRCHILSLGELDQASLQLFRHICQAMVNACDEQEECR RVKEEQEASLYKYKSKEHVSEEEEEKEFRQNFPQYTKDFSDLTSQPSLEQEDMDTEVQST EAKAADTAPVQQSSIQTVINIHQQIYLRFAQTVWYRQTGPAHQCSDYLNAFVSSYHTAAL LITQFCSLIDSSLNGELQGSQLLISSVIQNTVGGEETSELILPQEDTYDFYQHPNIQEAK KCQPILRSFTQKVKELLLDWPDHPALLQLLVVMDRIRSFPVSSALAKFLNGMEILLCKSQ DWEATASRSVSLRQHLDAVSQLIIQWRKLELNCWSSSLNVVMKRHMEKSTKHWFSIYQLI EKYLQERVEENLQGVEQQMKLPEVITTLQTFVEGATLGEFHFRLSMLLAFHCHVIAVPEQ EGKDDLCSLLWNLYNYYNQFSENVRVKITELRHPIEKELKDFVKISRWNDASFWSVKQSV EKTHRTLFKFMKKFEAVLNNPCRPALTETGSSGSLDNIDQQKQTRLQKLNCVLRKFSLEK CHVTQVFSPDIGKDDASGEGSSLQRRLPALSKRMRKMCLKLMTTNSLPSFVENLDQFTGD VITTVQDLQTLTVDQVADKDKQRSEIKHILMQKQRALADLFKHLTEIGLSYRKGLAWSRT DDPQDVFCLHPLDVKTAVNLISSGDELDNMLLAEISAAWEGCQKFFYQSLARRAALQVAM RTPAKELSLGNVERCQGFTAHLLKLLIKQRQCLTGLTEQWVSLRYLIKSLHKIQKSLADF KDHDVALPPQADVRLWMDQLRTLSMKSMIALEQLLWFLQCCPREKPFETYDELQDKPTST DQMDPGNAEMAAASSLPEDFVQPHLRFPTPLVEDYLPNACKMRRGDPTWQQVTQQVENML KEVKAVKAQVDEMSQQTSKTLLYSWTCFETCSMGISCLNRAMVQLQDIQTMFAAAASGNA SYCPALFKSLEYIKEEVSCAIAEFASWEKNLLNLTFDDSSVSSLVGSTLQVEPAINTVLC AVQAVVKQQQEENEKEQVGNKGNWDEEEPNKIQTGYLSKCLGQRLSSDITSLNLVKVISI VSDLLEKLKDYRQECTLKQYQLFNQSCHWIVQLLPMLTTYSELVLYYLTVSMATHRSSGK LLSVLSQLFTDLAVQGFCLPEELMEDAMGEGSTQFHDNESGGIGEGEGVKDVSDRIENED QVEDTFCKDQKKQEDTENMADIKEEENAIEMTEDFQGKLHDGDTKEPGEDDNDEESDSDE EELDKQMGDLENAEADKLDERLWGDDDDDEDSVHDEAEDTGPGMDVEKSELVAKDDNMDV ANESENDKKRQEEQEKEEERGEEEGREKIHEQLDEREYDENEVDPYQGNQDKQPETEALD LPEDLNLESEDGEKSDEDQEEGGDNPFDIEEKLRDFQEKSPDANETMEETAETEEEHAEQ EQEQDPQMDKENEGKADEQREGKEEDIGEDQDNGEEGDAEDIDQQKPEEDDQRAPAKKDQ EALCNEGQQPKVDEDTQDDQGVPQTEQRIEHEAEGKTGEENLQSDTAVELAGSASEKDKA EEEQGSGAADANQSEGHESKLMARVASQKQSLDKTQSYKRKPGHTDAERTVGDHNERVSK RLKMVEANIAAQQDVAQSEQKVMEADVYEHIKEGGESFDAQTFDVATAEQQNPSGSQQEK EIKEETESVEMETDQEEELQSVDVQELKPEKKFSSINAPGSDSNLEGEFQLPKPEEVDAA RDDSESENEEIPERSRESTIHTKHDLLTEDFEKRVVPDPAQLRKQLEEQLDAWRNEKSGS PEEEKAAAEMWQQYQALTAPLSQQLCEQLRLILEPTQAAKLRGDYRTGKRLNMRKVIPYI ASQFRKDKIWLRRTKPSKRQYQICLAIDDSSSMVDNHSKQLAFESLAVIGNSLSLLEVGQ VAVCSFGENVQLLHPFHEQFNDRSGARILRSCQFQQKKTKIAQFLESAANMFIAAQDQSQ LGKPEIAQLLLIVSDGRGLFLEGKERVTAAVETARRSNIFVIFVVLDNPDSKDSILDIKV PIFKDQGESPEIRSYMEEFPFPFYIILRNVNALPETLSDALRQWFELVTAADH NT seq 16722 nt NT seq  +upstreamnt  +downstreamnt atggaggacctggagtttcagttctcttctcttgcactgatcgccaagttaaacgacaag agcggcaccgagttgaacaaatacttgaccaaacagatttggaacgagcaggatcggcag tgtatccttagcatcttagctcaacttctgctggataaagattgcacgctgctaattggg cgccacctcaggcctttgctattggaccttcttgagcgcaatgttcggtcaattaaagga gccgtattcaaccatgatttacatgagaggctgtgtgtggcaatgagcaagcttattgat atcagccctgatgtcatttcgtttgcattgagatactttaaggattctccaccagtattc cagaggctgtttttggagagttcagattccagtgcagtccgatatggacggaaacgcatg aaactccgagacctcatgagtgcagcatatagacttttgaaggaaaactggataatgttc ggtaaattatgggattggagtgtatgcattccattgttgagaagccatgatacgttggtc cgctggtacactgctaggtgtcttgctgttgtaacaaacatgaatgatgaacaaaagaac catttcttcaagaaaattctcactgcagaagaactgacaacttttagactccagttgttg gaagaagctctgtgtctcaatgtggagaaggctttgatactggcaaattcgaagactgca ctgtggcagaaaacaaaacaattaaaatatacacaagggcacataatgtctggagattta tccgagaatgttgtggctgtatgcggagtagtgttaccacagaaacaactcattcatcaa gaccagttcatcggtcagcctcttgtgttagtagcctccacctacaattatctgcagagc ttggctatggcagttgcatcccagaatgctgtactgctggaaggaccaattggctgtggt aaaacgactttagtagaatatttagcagcactcacgggtcgacagaagccacctgatttc ctcaaagtacaacttggagaccagactgatagcaagatgttgctgggaatgtatcgctgt gcagatgttccaggggagtttgtttggcagccgggatccttgactcaagcagtaaccaat ggctattggctcctcttagaggacattgatcatgcacctttagatgtgatatcagtgctg atacctctcctggaaactggtgaacttctgatccctggtcatggcgattgcattaaggca gcacctggattccagttttttgccactcggagattgttcagcagcagcgttggttggtat agacaacaaagcagccatgcaactttgcttgataagctctggaccaaaatccaattggac agcatgaacaaagcagaactaaaggaggttttactaaatcggtatccaagtctagaaata gtaatagatcgtcttttggatatttattgccaactgactggcacgaaacatcaagggtca caggtcaccatggatggaaatcatgaaaacaaacaaccacctgttgaatgtgaaacaaaa actgatgataaagacttgtgccttgagggaagaggattatctttaagagatttattaaaa tggtgtgaacgcatcattgatcattttgattgcacttcctcttctacagctctccacatc tttcaggaggcgctggattgtttcacagctatgatgtccaaacgggggagcaggaagaaa atggccgaaataattggaagcaagctaaacatttcaaaagaaaaggtggagttcttttgc cgattgtgtaaacctgctgtagagttgagtgaagtggaagtgactgtcggacgggctgtt atcccacggcgaagaagtgatgtcgtcctgttgcagttggaaactcagacattttcagca acacggccctccgctctgcttctggagcagctggctgtttgcctaaggaaaaaggagcct gttttattggttggtgaaacagggactggaaaaacctctactgttcagtaccttgccaga attacaggtcacaaactgaaggtagtaaacatgaaccaacagagtgacacagcagacttg cttggagggtacaagcctgtggaccgtaaactacttatgctgcctttgcgagaagcattt gaagagcttttcattcagacgtactctaggaagcagaatattactttcttgggccatatt caaacgtgttgtaaacagaagcgctggcaggatttactccgactgatgctgcatgtctat aaaacagccatcaataaagagctaaaatctaaagaagacaaaggctggctgaaagataaa tgggaattacttggtctacgcctgacccaggctcagcagcaaatgaaacgagctgaatca gcattgatatttgcctttgtggagggtaccttagcacaggctgtgaagaaaggagaatgg atcttgttggatgagatcaatttggcttcagcagagactctggagtgtctgagtggacta ttggaaaggaatacaagctcacttgtgctgttggatcgaggagataccgaacctatacaa cgtgacccagagtttcgtttatttgcatgcatgaatccagcaacagatgtgggaaagaaa aacttaccaccaggcataagaaaccggttcacagagctgtatgttgaggaactagaagat gaaggagatctccgaatcctcgtatctgattacctgaaaggattaagtgtcagcaagaaa actattcaaggcatcattgagttttacttatctgtgcgtaaggagaaaaatgtcaagtta atggatggtacaggccatagaccccactacagtcttcgaactctctgccgtgctcttaag tttgcagcattgaactcatgcaacaatgttcaacgctcattgtatgagggtttctgcatg agtttccttactcagctggatcgtgtatctcacccaattgttgagaaactgatttgctgt catattattgggaacaatgccaaggctattctccaacagccaataccagaaccgaaagga ggacggtccatacagattgaaggctactggattgcaactggagataaggaaccttctgtt gacaagttgtatattctcacgccctctgtcaaacttaacctacgggatcttgcgagagtg gtagctgcagggatacatccagtacttattcaaggagagacatcagttggcaaaacaagt ttaatctgctggttggcagctgctacaggaaatcattgtgtgcggatcaataatcatgaa cacacagacattcaggagtatattggctgctatacatctgatgaaacaggaaaactggta tttaaagaaggcgtgcttatcaatgctatgcgaatgggccattggattatcctagatgaa ttgaatttagcccctactgatgttctagaagctcttaatcggctccttgatgacaatcga gagctctttataactgagactcaggaagtggtaaaagcacatccaagattcatgcttttt gcaacccagaatcctcctggactatatggtggcaggaagatgttgtcaagagcattcagg aaccgttttgtggaattacattttgatgaacttccaaaagctgaattagaaattattttg aacaagagatccagtttgcccccatcttactgtgcaaagctagtcaaagttatgctggaa ctgcagtcatatcgtagaggatcaagtgtttttgctggaaaacatggcttcattaccctg cgtgaactatttaggtgggcagaacgctacagattgactgaacaattaatgcctggttat gactggattagacatatagccactgatgcttatatgctcttggcaggccgtgtgaggaaa gaagaagaagtcactgttattcaccgtatccttgaaaaagaatttaaaaggaagcttgtt cctgaagttatgttctcaaaagacagtcttcaaaaaagaatggatcagtggccaagtctg acatcagtcatgtctgatgactttcgccatgtcgtgtggacatatggaatgcgaaagttg gcaattctggtaggacaaggtttgcggtttcgagaagctgtgctaattgttggagaaact gggtgtggtaagaccacagtgtgtcagatgttcgcttccttgttcaatcagaagctgcac acagtgaattgtcatttgcacttggagacatctgacttccttgggggtttgaggcctgtc agacatagttgcagtgaagaagatggtgccaaccccaacagactgtttgagtggcacgat ggacctcttgtacttgcaatgaaggaagataacatgtttctgatggatgaaatctcactg gcggatgattctgttttggaaagactcaacagtgtgctggaagatgaacagacactcttg ctcgcagaaaagggaagtgcagaagatgatactgtggagctcattacagctggaaacaga tttaggatacttgcaaccatgaatcctggaggtgattttggcaagaaggagctttctcca gccctgaggaacagatttactgagatctggtgtccaccaatcaatagccgtgaggatatg ctggcgataattcaacataacctaagccctggactttctttccatgagcaagatcatcaa ggtgaagatatagctgaacttattttggattttattgactggttaaagaatcaagagttt gggcgccgatgtgtgttaagtatccgagatctcctgtcctgggtggaattcatgaatgtt acaacaaggaaagcgactgcagatgtcgtggatttggatgaaattggtgattttcagctt gatcctgtgactggattcatacatgctgcatgtctcacctgtatcgatggaattggaaca gggtctgcattttcttctccagaggctactttagctgcacgcaaagcatgcctgagcttc cttttaaagaaactgtccaaggtcgcaaagttgaccaaacatatgtggaatatgctaaat agttatgatcagaaaagaaagaggaaagttgtatggactgaaagttattttggaattcat ccattctacattcccatagtaggggctgttggagagaaagcggcagtcacagactatgca ctgaatgctagcacaacagcaatgaatgcccagaggctgttgcgagcaatgaagttaaag aggccgattctattagagggatcaccaggagttggcaagacaagcttggtagcagctctg gcaaaggcctctggaaatcagctagtccgaatcaatctttcagagcaaacagatgtgact gacttgtttgggacagacctgcctgttgagggaggtaaaggaggtgaatttgcctggcgt gatggccctctgcttgcagccctcaaggctggacattggattgtcttagatgagttaaac ctagcttcccagtctgtgctagagggactgaactcctgctttgaccatcgtgctgagatt tttatccccgagttgggtcgttgcttcattgtggagcataacaggaccaagatctttggt tgtcagaatccgtatcaccaaggaggtggaaggaagggtctccccaagtctttcctcaat cgattcacacaggtttatgtggatcagctttcagttaaagacatggagtacattgctgac accatgtttcctgcgattggtaaaaatattgtaagcaaaatggttcagtttaattacaag attaaccaagaagtaatggtggaaagaaaatggggacagaaaggaggaccgtgggagttt aacttgcgggatctctttcggtggtgccacctgatgttggtggaccagatgcctggatgc tatgatccagggcaacatgttgctttggtatatgtggaccgaatgcgatccaatgcagac agaaaccatatgttttctatatttgaagaaatattttctttagaagatgttggaattcac tctcatccctacactgggtccagaaaattccacatcacaccacagcaggttcaggttggt tattccatactttctcgtaatgggttcatcattcccatgacaaacaagcagctgtccatt cttcaccattcacttcagccactggagtccattatgaagtgtgcacagatgggctggatg gttattctagtggggccagttgccagtgggaaaaccagcctcatccagctcttggctctt ctgacaggccaaaacttaagagtcatggcaatgaacagtgctgtggacacaacagagcta cttggtggatttgagcaggttgatattacacgtccatggcagcgtttagttggaaaggtg aaagatgttgtcagtgctatcaccagagatgttctgctctccatggactctggccctgat gatggtgttcttctcaaattctggaattcattccttctcagtcattcgtgttgcctgaat gaagactgtgattctgccatttcttctgatgcagtgaacaaactggagaatttacttatt ctcctccagcgttttaacaacaaagtgaacactctgtcacctgcagaattttcggaattg atctcagaattccaacattttaagcaccgacgcagtgaatccttggacggccaaaatcgt ggcacttttgagtgggtggatgggatgcttgttcaggctttgaattctggtgactggctg ctactggacaatgttaacttctgcagtccttctgtgcttgatcgtctaaatgctcttttg gaacctggaggagtgcttactgttagtgaaagaggagtgattgatggcaccaccccaact attgttccacacccaaacttcaggctctttatgaccatggatccggcacatggggaaatc tctcgggccatgagaaatcgtgggattgagatttatgttgcaggtgaacacagtgctgac cctttagataaacaggacgttaaaacactgttacatggtcttggttttgtgggagaccaa atgtgcactgagttgatgacattgtattcagaagtaaaggaaattacagcaggcacttct tactccatctcttcacttctccactgtgccgtcctcatcgttcaccagctgaagcgtggt ctcagcttggcagaggcattccatcaagcttgcacgcaagtcttcgtcctttcacagtct tctcaaactcaacaagagcaagtacgagagctagtggaaaagcacaaacttaaattgatg tcatgtgagtcctggggtgattctttggtctctttgggattgtggccggattctattcca tcggcagtgtttaccgcagaggaatccatgttgtccatggttcatcgagacggacaggtc ctggcctactgtttaaaccaactgagcctaagcaataacagatctcgacctctaactctg actgatcttgagttagttttgcaatcctctaatatggacagtcttgtattccatgacaat aagacagcagttcaagcgactgatgagctctcaatgattcctgctgctatcaggctggtc atggagaaagcatctaatcaagattggctattaagggcccgatggttgtgccacgcagca aaagtctacaagcatttaccagagttggtatgtgctcaactggaggcaggggcaaaagct cttaatgcagtttactccagtgtacttcccacgggaatgaaagaagttgtacagcaacta cagctcgatgccaatgagagtgcctcagttcctttggattcacgatggaaccagcagcat ttggatattttattaaattctgtggcatactctgggctgcattgttcaaaagagcttcaa gcacagctccactccattgctaacaggatggcacttctgatggacagagaggaaagagga tacatggagaaggcatcactatcctctgatgctgcaagaaaatcaggcagacaaagtgct ttaagggtgtcagtcgcattccagaaaggaatgatgagctttgatgacctgcctcaccca gtcttggctcaccttgctgctttctttgaagcctgggatgcttgcattgtgcagtgcata aagtcttcattttccaatctagaagatgatgccttccatgaggtattgtgcagcactttg tggcgggatcgattctggttagtatctgacagagttgttacagatactgagggaatagcg ctcctctctctccactggcactggatgatgaagcatctcctgaaagatcatctctgtcag ctaactgacttttcccaaattcctcaagaaattcacacgatttcagtgaatctgcagagc catctggcaagtcctagtgaaatgattgccagtgtgaagggactgcagaaatgtttgggt cgtcctcttccgttcaaggttggatctgttgtggaatgtgtgtctaaactcaaggtgatg agttctgttctggatgtgttgaaattgaggccaaaaatgatggatgcgacttggaaagaa caactatatagaattaaaaccactgctactgactggaaggttaagcggggcttgatgttg gcttggggtctcgtaattcaagcaaatcacgtagtaggatatgatgctggtgtcttgcag catgtggtagactcccaagcttcagcaatgacatctcagggacttctaaactcttcagat tctcaaagccttaaggcggatccacctcagctcgacggagcatgtttgaatcagttagca agtagaattcagctgtggcccgtactggaatatctggcattgctctccaagtataaagtg gtggcagaccttatggatctatcattagtgtccagcagtgccagaagcaagccggatcag tcagtggttggtgctgaacttcgtcaattaattacattctgcttaagatttactcccatg gctgcccaagatctccgagaattttggtacttagcgcaagttgatgagctctctcctgaa gaattaaaattgctgagttcaggactgatgatgaccacgtttggaccattttggagtagt tctatcacaaccgatcctgactattggctaacctggaaacccccagcaattataggagat gacatggttccagaagataccattgacaaatcgttaaagggacctggcattttatgtcgc gctatccaatctaagtgtttctttgaaattctggccaacactaatcgaagccactctgtg tcctttggtggaattggtatgacaatggcaactcatgtaactctgggagagtggctggag cgaactcgacaattacaagacatcagttcagtgttgtggaccaacatggctgttggttcc tttgctgaattcagattcacagattccagattgcagtgcacaatgctactcaaacagctt catgcaataaaggactttttgccaaaagaacttcaggaggagtatttacagacatgtgac caacttgccattgaaaaaaccagtatagccagtcacagtattcagagtttgctcagcagt cttgcagagcagggattactgcccgaagatgttgtttcacttcttgtgacctgtgtacgg aaatttgtgggtaaagaaaaggattttagaagcctttcagagaaagcccagagaggctgt ctatgggtaaacctgggattgctacagattcagatttggacaccacagaccatgtttgat cctgctgtcaaaaaactgtacaagctgaattatatcaaggaggagttgcaacaattgcag agtgaatggaagagtcgcaacctgtctgaacagttattgactggccgagaactgttacaa gaaggagagaatagacattgtcatccgcgaattaggtttttgcaacaaagaatcaatctc ctgaaggaacagattgcagcactgtccagaaagcaggcgcaccgccccagtgtacctcaa tacgattatctcttccaagatatccaccactatgtgaacactattgcacagaagtccaaa gtcaaatccctcctctctcgactgctacagcccctacaggcgaagcggcctaaaccatgt cagagtgtccagctcgtactgaatgaggaggcagcttggcagcagtcccatcaccagttc aggagacgaatcgcagaagagtactgtcaatatcctgacattgttgaaccccttcttgct gccattttacagatgcagcatggcatgagacttctggcatctgaggttcacgtgtcgcta aataataagcttgttaagcaggctggcctcacgcgacttgtcacttgccttttggccttt ccttccatcagcttctcattcccaacttaccttgctcaggcagatgaattatgttcaaaa gcctccttggagaccctcaaagggcttaatcagctcctgcgtaagagctcatcagatgaa aagtctctggctaaggaacaaaggttgctgccaacacaagaacagctgctgatgaatgcg 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gatgaccctcaggatgtattttgcctgcatccacttgatgtgaagacagctgtaaatctg attagcagtggtgatgagctggataacatgttgcttgctgaaatttctgctgcatgggaa ggctgtcagaagtttttctatcagtctcttgcacgtcgtgctgccctccaggtggcaatg cgcactcctgccaaggaacttagcctgggtaatgttgaacgttgtcaaggatttacagct catctgctgaaacttttgatcaaacaaaggcagtgcctaactgggctaactgagcagtgg gtcagcttgagatatctgattaaaagtctacacaagattcagaaaagtctggcagatttc aaggaccatgatgtggcacttccaccacaggccgatgtcagactttggatggaccaactg cgcaccctgtcgatgaagtctatgatagccttggagcagcttttgtggttcttgcagtgt tgtccaagagagaaaccatttgaaacatacgatgagctgcaggacaaacccaccagtact gatcaaatggacccaggaaatgcagaaatggcagcagcatcatcattacctgaggatttt gtccagccccatttgaggttccccacacccttggttgaagattacttgcccaatgcttgt aaaatgcggcgaggagatcccacatggcaacaggtgactcagcaagtggaaaacatgttg aaggaagttaaagcagtaaaggcacaagtggatgagatgagtcagcaaaccagcaaaact ttgctatattcatggacatgttttgagacctgttcaatggggattagttgtttgaataga gccatggttcagctgcaagatatacagaccatgtttgctgctgctgcttctgggaatgca tcttactgcccagcactgttcaagagcctagaatatattaaggaggaagtcagttgtgct 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aatgatcggtcaggagcaagaatactgaggagctgtcagttccaacagaagaaaactaag atagctcagtttctggaatctgctgccaacatgtttattgcagcacaggaccagtcccag ttgggaaaaccagaaatagcacagttactgttgatagtgtctgatggacgaggtctgttc ttggaggggaaagagcgagttacagcagctgttgagactgctcgacgcagcaatattttt gtcatctttgttgtgctggacaatcctgactctaaggattccattctggacattaaagtc cctatattcaaggatcaaggtgaaagtccagaaattagatcatatatggaagaattccca ttcccattctatataattctacgaaatgtgaatgccctcccagaaacactcagtgatgct cttagacagtggtttgaactagtgacggcagctgatcattaa

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