Streptomyces albidoflavus: XNR_3533
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Entry
XNR_3533 CDS
T02545
Name
(GenBank) Uroporphyrinogen-III methyltransferase / Uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
salb
Streptomyces albidoflavus
Pathway
salb00860
Porphyrin metabolism
salb01100
Metabolic pathways
salb01110
Biosynthesis of secondary metabolites
salb01120
Microbial metabolism in diverse environments
salb01240
Biosynthesis of cofactors
Module
salb_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
salb_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
salb00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
XNR_3533
Enzymes [BR:
salb01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
XNR_3533
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
XNR_3533
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AGI89872
UniProt:
A0A126Y5W0
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Position
4049884..4051521
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AA seq
545 aa
AA seq
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MFSDHGHVTFLGAGPGDPGLLTLRAVEALAAADVLVAEEQVLDVVRAHARAGADMPQLSA
DEASTPAEARRFGDAANLVMGAARAGKRVVRAVQGDPGLDSEAVREMLACAAEGVTFEVV
PGIAEAVGVPAYAGIPLRDETGADVRFVDARTATERCWTELGASDGTVVVSTSLDQAAAT
AGELVAAGRKPDTPMTLTVAGTTTRQRTWEATLGTVAQVLKQAKVLPSPDGGRPVIAVVG
EHCAPARRDQLSWFESKPLFGWKVLVPRTKEQAASLSDQLRSYGAVPHEVPTIAVEPPRT
PQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFEEYGLDARAFAGIKVAAVGEQTAAAL
IAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPIDRVFLPRADIATETLVAGLIELGWEV
DDVTAYRTVRASPPPADTREAIKGGGFDAVLFTSSSTVRNLVGIAGKPHNVTIIACIGPA
TAKTAEEHGLRVDVMAPEPSVHKLAEALASFGAERRAAALEAGESVARPSERRPGARRRR
AASSS
NT seq
1638 nt
NT seq
+upstream
nt +downstream
nt
atgttctccgaccatgggcacgtcaccttcctcggtgccggtcccggcgacccggggctt
ctcactctgcgcgccgtcgaggcgctggccgcggccgacgtcctggtcgcggaggagcag
gtgctcgacgtcgtcagggcgcatgccagggcgggcgcggacatgccgcaactgtccgct
gacgaggcgtcaacccccgcggaggcccgccgattcggcgatgccgccaatcttgtcatg
ggggccgcgcgggccggaaagcgggtcgtgcgcgccgtccagggcgacccggggctcgac
tccgaggccgtccgcgagatgctcgcctgcgccgccgagggcgtcaccttcgaggtggtc
cccggcatcgcggaggcggtcggcgtccccgcgtacgccggtatcccgctgcgcgacgag
accggtgccgacgtgcggttcgtggacgcgcgcaccgccaccgagcgctgctggaccgag
ctgggtgcgagcgacggcaccgtcgtcgtctccaccagcctcgaccaggcggcggccacg
gcgggcgaactggtggcggccgggcgcaagcccgacaccccgatgacgctcaccgtcgcc
gggaccaccacccgccagcggacctgggaggcgacgctcggcaccgtcgcgcaggtcctc
aagcaggccaaggtgctgccctcgcccgacggcggccgtccggtcatagccgtggtcggt
gagcactgcgccccggcccgccgcgaccagctctcctggttcgagtcgaagccactcttc
ggctggaaggtcctggtgccgcgcaccaaggagcaggcggcctcgctctccgaccagctg
cgctcctacggcgcggtgccgcacgaggtgccgaccatcgccgtcgagccgccgcgcacc
ccgcagcagatggaacgggccgtcaagggcctggtcaccggacgctacgagtggatcgcg
ttcaccagcgtcaacgcggtcaaggcggtccgggagaagttcgaggagtacgggctcgac
gcgcgggccttcgccggcatcaaggtcgccgccgtcggcgagcagaccgcggccgcgctg
atcgccttcggcgtcaagcccgacctcgtcccctcgggcgagcagtccgcggccgggctc
ctggaggactggccgccgtacgacccggtcttcgacccgatcgaccgggtgttcctgccg
cgcgccgacatcgccaccgagaccctggtggccgggctgatcgagctgggctgggaggtg
gacgacgtcaccgcctaccggacggtgcgcgcctcgccgccgccggccgacacccgcgag
gcgatcaagggcggcggcttcgacgcggtcctgttcacctcgtcctcgaccgtccgcaac
ctggtcggcatcgcgggcaagccgcacaacgtcacgatcatcgcctgtatcgggcccgcc
accgccaagacggcggaggagcacgggctgcgcgtcgacgtgatggcgcccgagccctcg
gtgcacaagctggccgaggcgctcgcctccttcggcgcggagcgcagggccgccgcgctg
gaggccggggagagcgtcgcccggcccagcgagcggcgccccggcgcccggcgccgcagg
gccgcctcctcctcgtga
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