Streptomyces albus: SLNWT_5799
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Entry
SLNWT_5799 CDS
T03823
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sals
Streptomyces albus
Pathway
sals00300
Lysine biosynthesis
sals00550
Peptidoglycan biosynthesis
sals01100
Metabolic pathways
sals01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sals00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SLNWT_5799
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SLNWT_5799
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SLNWT_5799
Enzymes [BR:
sals01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SLNWT_5799
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
DUF2126
Motif
Other DBs
NCBI-ProteinID:
AJE86175
UniProt:
A0A0B5F3J8
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All DBs
Position
6724550..6725980
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AA seq
476 aa
AA seq
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MIALSLAEIARAVGGQIHDIPDPAVEVTGPVVKDSREVEPGSLFAAFAGARSDGHDYAAE
VVAKGAVAVLAARPVGVPAIVVEDVQSALGALARTVVQRLGATLVAVTGSAGKTSTKDLI
AQVLTRKAPTVWTPGSFNNEIGLPLTALSATEGTRYLVLEMGARGIGHIRYLAGLTPPRI
GVVLNVGSAHIGEFGGRAQIAEAKGELVESLPAEGAAILNADDPLVRAMASRTKARVLLF
GEAGEADVRAENVRLTADGRPSFALHTPSGCSEVTLRLYGEHHVSNALAAAAVAHELGMS
AEEIALALCAAGSLSRWRMEVTERPDGVTVVNDAYNANPESMRAALRALAAMGEASRAEG
GRTWAVLGQMAELGDEALAEHDAVGRLAVRLNVGKLVAVGGREAAWLRMGAYNEGSWGEE
SVHVSDAQAAIDLLRSELRPGDVVLVKASRSVGLERVAEGLLEGFAASSEGQVAGR
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
ttgatcgccctctccctcgccgagatcgccagagccgtcggcgggcagatccacgacata
ccggatccggccgtcgaagtcaccggaccggtggtgaaggactcccgtgaggtggagccc
ggttcgctcttcgccgccttcgcgggcgcccgcagcgacggacacgactacgccgccgag
gtggtcgccaagggggccgtggcggtcctcgccgcccgccccgtcggcgtgcccgcgatc
gtggtcgaggacgtgcagagcgccctcggcgccctcgcgcgcacggtcgtgcagcggctc
ggcgccaccctggtcgccgtcaccggctccgcgggcaagaccagcaccaaggacctgatc
gcccaggtgctcacccgcaaggcgcccaccgtgtggacgccgggctccttcaacaacgag
atcggcctgccgctcaccgcgctcagcgccacggaggggacgcgctatctcgtactggag
atgggagcgcgcggaatcggccatatccgctacctcgccgggctcaccccgccgcggatc
ggtgtcgtcctgaacgtcggcagcgcccacatcggggagttcggcggccgggcgcagatc
gccgaggccaagggcgaactcgtcgagtcgctgcccgccgagggcgccgcgatcctcaac
gccgacgatccgctggtccgcgcgatggcctcccgcaccaaggcgcgggtgctgctcttc
ggggaggcgggcgaagccgacgtacgagccgaaaacgtgcggctgaccgccgacgggcgg
ccgtccttcgccctccacacaccctccgggtgcagcgaagtgaccttgcgcctgtacggt
gagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgaactgggcatgtcc
gcggaagagatcgccctcgcgctgtgcgcggcgggctccctctctcgctggcgtatggag
gtcaccgagcgcccggacggcgtgaccgtggtcaacgacgcctacaacgcgaaccccgag
tccatgcgagcggcgctgcgcgcgctcgcggcgatgggcgaggcctcacgggccgagggg
ggccgtacgtgggcggtgctcgggcagatggccgagctcggggacgaggctctcgccgaa
cacgacgcggtcgggcggctcgccgtccggctgaacgtgggcaagctcgtggctgtcggg
ggcagggaagccgcctggctgcggatgggcgcatacaacgagggttcgtggggtgaggag
tcggtgcacgtgtccgacgcacaggcggcgatcgatctactgcgcagcgagctgcggccg
ggggacgtcgtactcgtgaaggcatccaggtcggtcggcctggagcgggtggccgagggg
ctgctcgaaggcttcgccgcgtcttccgaggggcaggtcgccggccgatga
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