Sinocyclocheilus anshuiensis: 107671773 Help Entry 107671773         CDS       T04917                                  Name (RefSeq) ryanodine receptor 3-like   KO K04963   ryanodine receptor 3 Organism sanh  Sinocyclocheilus anshuiensis Pathway sanh04020   Calcium signaling pathway sanh04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:sanh00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     107671773    04020 Calcium signaling pathway     107671773  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:sanh04040]     107671773 Ion channels [BR:sanh04040]  Voltage-gated cation channels   Ryanodine receptor    107671773 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY MIR RIH_assoc Ion_trans Ins145_P3_rec EF-hand_7 EF-hand_1 Ago_Mid EF-hand_6 EF-hand_8 Motif Other DBs NCBI-GeneID:  107671773 NCBI-ProteinID:  XP_016320219 LinkDB All DBs Position Unknown AA seq 4700 aa AA seqDB search MICAIKGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERYLHLSISNGSIQVDASFM QTLWNVQPTCSRSNMEVGFLLGGHVTRLFHGHDESLTIPGSEQSQEQQSWSGSHIRWGQP FRLRHLSTGHYLGQTEDNGLILLDREKSDTTATAFCFRSSKEKIDSGPKRDIDGMGVAEI KYGDSVCFIMHVSTGLWLSYQAPDAKSSRLGPLKRRAVLSLEGHMDDGLTLQLCQHEESR AARIIRNTTRLFTQFIRGLDGLNGEKTTEVTLPVCEVLQTLDDLIVYFQQPDSELEHEEK QRQLRSLIKRQDLFKEEGMLTLVSHCIDRLNVYNSAAEFEELAGEEAGEAWKDILNLLYE LLAALIRGNRTNCTQFSRKLDWLVSKLERLESSSGILEVLHCILIESPESLNIIQKAHIK SIISLLYKHGRNHKILDVLCSLCVCNGVAVRANQNFICDHLLPRRDLLLQTRLINDVQSM RPNIFLGMSEGSAQYKKWYFELIIDQVDHYVTSEPTHLRVGWATTKGYAPYPGGGEGWGG NGVGDDLYSYGFDGLHLWSGRIPRAVASINQHLLNSDDVVSCCLDLGAPSMSFRINGQPV QGMFEDFNVDGFFFPVVSFSAGVKVRFLLGGRHGDFKFLPPAGYAPCYEALLPKEKMRVE PVKEYKRDLEGVRDLLGTTKFLSQASFIPVPVNTSQIVLPPHLENVRDKLAENIHELWGM NKIELGWMHGKVRDDNKRQHPCLVDFSKLPETEKNYNLQMSTETLKTLLALGCHVAQVNI NAEDDLKKMKLPKNYMMANGYKPTPLDLSDVKLTPGQEVLVDKLAENAHNVWAKDRIKQG WTYGIQQDLKNRRNPRLVPYALLDERTKKSNRDSLREAIRTLVGYGYFIDPPDQETAHIV EKEGIESIRLFRVEKTYAVKTGKWYFEFEALTGGDMRVGWARPGCRSDMELGLDDQSFVF DGYRGRRVHMGSHFFGRTWTKGDVVGCMINMEDKSMIFTLNGEIVITNKGSELCFADFEA EDGFIPVCSLGLSQIGCMNLGKDASTFKYYTMCGLQEGFEPFAVNMNREVTMWFSKRLPT FVNVPEDHPHIEVTRIDGTVDTPPCLKVTHKTYGTQTSNDDMVCCRLSMPVEFPWKITDV SEVIAEDQKAKKDDGGKIDYGSITKYFYSVRVFAGQDPSSVWVGWVTPDYHYYSKHFSLS TVRTVTVTLGDERGRVHESVRRSNCYMVCAGDVVSGSTGRSNTDLEIGCSIDLASGLVSF TANGRDLPTAYQVEPNTKLFPAVFVQPTSPNLFQFEFPKIPDAMPLSSAIFKSLQRNPEP QCPPRLDVQTIVSVLWSRMPNTFLSVETARVSERHGWVVQCLEPLQMMAVHIPEENRCID IMELSENEDLRQFHYHTLKVFCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLSGQLRE GFYDVLISIHLETGKEAHLMMNNEFIIPVTDETRSIRLFPDDSKRHSLPGVGLSTSLAPR FNFTPPYFITPKRDLPLFSPQIPLGILKEKAISMLTEAVQGGGAHIRDPVGGSVEYQFVP ILKLIGTLLIMGAMTSEEVRTILLLIDPGVFGDGKEEEEQTAVAEQGAEKEEAASNEEKA VEAGEEESKEAKQSPKGLLEKSLPESVKRQMCELLHYFCDCELKQRIEAIVAFSDDFVSK LQFNQKFRYNELMQALNMSAAVTAKKTREFRSPPQVQINMLLNFSAGDDCTCPEELQEEL QSFHDDLRLHCGIPMEEEEEEQDTSLKGRLMSLVYKIKGRPQKTEEKPTEQEQAAPTNLK ELISQTMVTWAQECKIQDPALVRSMFSLLRRQYDGIGELLRALRKSYTISAKSVWDAINL LASLGQIRSLLSVRMGEEEGQLMIDGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVL GGGKDKEIAFPKMVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLACPAMRGSTP LDVAASSVMDNNSLALALEEPDLEKVVTYLAGCGLQNCPMLIARGYPDIGWNPIEGERYL SFLRFAVFVNCESVEENANVVVKLLIRRPECFGPALRGEGGQGLLAAMKEAIKISEDPAL DLPNLPEGAAHTVGEDEEEEEVAHMGNSIMSFYSALIDLLGRCAPEMHLINKGKGEALRI RAILRSLVPMKDLVGIISIPLKMPVVNKDGTVTEPDMNASFCPEHRAPMVLFLDRVYGID DQSFLMHLLEVGFLPDLRASASLDSEVLRTTETALAMNRYIGSAVLPLLTRCAHLFAHTE HYATLVDSTLHTIYRLSKGRSLTKAQRDAIDECLLAICMHLRPSMLQQLLRRLVLDVPQL TEYCKMPIKLLTNHYEQNWKYYCLPTGLGSYGMASEEELHLTKKLFWGLFDALSQKKYDA ELFKMAMPCLSAIAGAIPPDYVDSSPGSTLVKQASVDAQGNFDPQPISTANISLPEKLDY IASKFAAHSHEKWSSEKIALGWTAGDKVDDKAKTHPLLKPYKALSEKERETYRYPVKETL KSMLAMGWNIERAKEGEAMFQQRESEKQRKISESSQGEFIPAPQDLENVILSRELQAMVE TVAENYHNIWAKKKKKELDSKGGGSHPLLVPYDTLTAKEKYRDREKAQELFKFLQVNGYA ISRGLKDMEQDSSSMEKRIAYKFLKRLLNYVDSAQEFIAHLEALATSGKTEKSPHDQEIK FFAKVLLPLIDQYFKNHCLYFLSSPNISLSSSGYASNKEKEMITSLFCKLAALVRHRISL FGSDSTTMVSCLHILSRSLDFRTVMKSGSELVKAGVRTFFENAAEDLEKTLENLKLGKMG QSRTQMKGVTQIISYTSAALLPILTVLFQHITQHQFGVELLLDDIQLSCYRILTSLYSLG TGKNIYVEKQLPVLGECLSTLVGAMPVAFLEPHLNMHNPQSVFNTKTPRERAILSMPDTV DEMCLEMPHLDGLMKDIGDISESGARYTEMPQVIEVILPMLCNYLSYWWAKGPENSPVDT NCCTTVTSEHLSLILGNILKILNNNLGIDNAPWMKRLAVYSQPIISKASPDLLRMHFLPT LEKLKKKTVKIVAEEELLRAESRTDTQEAELQILDEFAVLCRDLYAFYPMLIRYVDNNRS KWLKQPDSDSTELFKMVSEIFILWCKSHNFKREEQNFVVQNEINNLAFLTGDSKTKMSKS GDDESGGQDQDRRGKRRKGELYSIQTSLIVAAHKKMLPIGLNMCTPGDQELISLAKIRYS LKDTDDEVKDYLRKNLHLQEKSADPAVQWQVNLYRDVVVKNEGPPDQEHNVERVQSISAA VYHLDQVEQPLRNKKMVFQKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFLSGYQRLWI ETEEYSFEEKLVQDLAKTPMTVVEEEEEEEAAVQPDPLHQLILHFSHNALTERSFLEEDP LYIAYADMMAKSCAENEEEEEEEEGKEKTFEEKEMEKQKILYQQARLHARGAAEMVLQMI SASKGRLGPMVTGTLKLGISILNGGNVLVQQKMLDYLKEKRDAGFFKSLSGLMMSCSVLD LNAFERQNKAESLGMVTDEGSINVKERGSKVLQNDDFTKDLFRFLQLLCEGHNNDFQNFL RTQSGNTTTVNIIISTVDYLLRLQESISDFYWYYSGKDIMDEAGQLNFSKALAVAKQIFN SLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDSSQIELLKELMDLQKDM VVMMLSLLEGNVVNGTIGKQMVDTLVESSSNVEMILKFFDMFLKLKDLTTSDNFKEYDPD CKGVISKKEFQKSMDSQKQYTQSEIEFLLSCVEADENDMFNYKEFVERFHEPAKDIGFNV AVLLTNLSEHMPHDSRLSTFLDLAESVLSYFEPYLGRIEIIGGAKRIERVYFEISESSRT QWEKPQVKESKRQFIFDVVNEGGESEKMELFVNFCEDTIFEMQLASQISEPDAAERPEED EDEELHSLLEGLSEKEDSSLESASAFTAACASVKKSMSNFRKMLTFKSMRKQLKKFRKLT IREMITGFFSFFWMLFTGFFKGIFAIIFGFFHIIWSSMFGGGLVEGAKNMKVTDILGNMP DPTQFGIHGDVMEAEKSESSELVVSADMVQMTGAGAEKLETDMIMDLLNPAVKKEGKHVA ELGLGDVCEVLTESSSPVEKKKSQKVAAEKPESEPEKADTENQEKEDKAKEETPEEPAAA KPAPKAKRGSAKEEAPAFMASFFAGLEVYKAKMLNYLARNFYNLRLLALFVVFAINFILL FYKVTGEFDDEEEEGSWGGEEEEGDEDDEGMEYFILQENTGYMAPTLTFLAVLHTIISLL CVVGYYCLKVPLVVFKREKEIARKLEFDGLYITEQPSDDDIKGQWDRLVIATPSFPNNYW DKFIKRKVINKYGDLYGAERIAELLGLDKSALDFDPTEEAVVKEASLLSWLSSIDTKYHI WKMGVVLTDNSYLYLIWYTTMSILGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQL VLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDAPDMKCDDMMTCYLFHMYVGVRAGGGI GDEIVDPAGDPSELYRILFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETK CFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEYTGQESYVWKMYQER CWDFFPAGDCFRKQYEDQLG NT seq 14103 nt NT seq  +upstreamnt  +downstreamnt atgatttgtgctatcaaaggggaagcttgttggtggacaattcacccggcatccaagcag aggtcagagggtgagaaggtgcgcattggagatgacctcatcttggtcagcgtgtcctct gagaggtacctgcacctctccatctccaatggaagtattcaagtggatgcttcattcatg caaacactgtggaatgttcaacctacctgctccagaagcaacatggaagtgggatttctt ctgggtgggcatgtgacacgcttgttccatgggcacgacgagagcctcaccataccagga tccgagcaaagccaagagcaacagagctggagcgggagtcacatcagatggggtcagccc ttccgcctacgccatctctccaccggtcactacctgggccagacagaggacaatggcctg atactgctggacagagagaagtctgacaccactgcaacagccttctgtttccggtcaagc aaggaaaagattgactctggcccaaagcgtgatattgatggtatgggggtcgcagagatc aaatacggcgattccgtctgcttcatcatgcatgtgtccacgggcctgtggctgtcctac caggcgcctgatgccaaatcttctcgcctgggaccactgaagagaagggctgtcctgtct cttgagggccatatggatgacgggctgactctgcagctttgccagcacgaggagtcccgg gcagctcgcatcattcgtaacaccactcgcctcttcactcagttcatcaggggtctggat ggtttgaatggggagaagactacagaggtgacactgcctgtgtgtgaagtgctgcagaca ctagacgacctcatcgtgtacttccagcagcctgactctgagctcgaacatgaggagaaa cagaggcagctccgatctctcatcaagcgccaagatctcttcaaagaagagggaatgcta accctggtctcacactgcatcgatcgtctaaacgtgtacaacagtgccgctgagtttgag gagttagcaggcgaggaggccggagaggcctggaaggacattctcaacctcctctatgag cttctggccgctctgattcgaggcaacaggaccaactgcacacagttctctcgcaagctg gattggctggtcagcaagctagagcgattggagtcctcatcaggcattttagaggtgctt cattgtatcctaatcgagagtccagaatctctgaacatcatccagaaggcccacatcaaa tccattatttctctgctgtacaagcatggacgcaaccacaagattctagatgttctctgt tccctgtgtgtctgcaatggtgtggctgtgagagccaatcagaacttcatctgtgaccac ctgcttcccaggagagacctgctgctccagacacgattgatcaatgatgtccaaagtatg agacccaacatcttcctgggcatgagtgagggctcggcacagtataagaaatggtacttt gagctgatcatcgatcaagtagaccactatgtgaccagtgagcccacccaccttcgtgtt ggctgggccaccaccaaaggctacgccccatatcctgggggtggagagggctggggagga aacggtgtgggtgacgatctttactcctatggttttgatgggcttcatctgtggtcaggc cgaatcccacgggccgtggcctctattaaccagcacttgctgaattcagacgatgttgtg agctgctgtctggatctcggagcccctagcatgtctttccgaattaacggtcaacccgtt caaggcatgtttgaagacttcaacgtagatggcttcttctttcccgtcgtcagtttctca gcaggggtcaaggtccgtttcttgttgggtggacgccatggagactttaagttcctgcct ccagcaggctatgcaccatgttatgaagccctgctccccaaagaaaagatgcgtgtggag cctgtgaaggagtataaaagagacctggagggagtgagagatctgctgggcaccacgaag ttcctgtcccaggcttccttcattcctgttcctgttaacaccagccagattgtcctgcct ccacatcttgaaaatgtgcgggacaagttagctgagaacatccatgagctctggggcatg aacaaaatagagcttggctggatgcatggcaaggtccgagatgacaacaagagacagcac ccttgtcttgttgacttctctaaactgccagaaacagaaaagaattataacctgcagatg tcaacagaaactttgaagaccctacttgctttgggatgccatgttgcacaagtcaatata aatgctgaagacgacctgaaaaaaatgaaactccccaagaactacatgatggcaaatggc tataaacctacaccactagacctttctgatgtgaaactgacacctggtcaagaggttcta gttgataaattggctgaaaatgctcataatgtttgggccaaagatcgcatcaaacaagga tggacctatggtattcagcaggatctgaaaaaccgtcgtaatccacggctggtgccatat gctttattagacgaacgcactaagaaatcaaacagagacagtcttcgagaggccatccgt actctggttggttatggatattttatagacccacctgatcaagagactgctcacattgta gagaaggagggcattgaatccatccgtctcttccgtgtggagaagacctacgctgtgaag acagggaagtggtattttgagtttgaggcgctcactggaggtgacatgcgggtgggctgg gcacggcccggatgcagatctgatatggaactgggactagatgaccagtcctttgtcttt gatggctacaggggccgccgggttcatatgggcagtcatttctttgggaggacgtggact aaaggagatgtggtgggctgcatgatcaacatggaggacaaatccatgatattcaccctg aatggagagatcgtaatcaccaacaagggctctgagctctgctttgctgactttgaagct gaagatggattcatcccagtgtgcagcctgggtctttcccaaattggctgcatgaattta ggaaaagacgctagtacttttaagtactacactatgtgtggccttcaggagggctttgaa ccctttgctgttaatatgaatcgagaagtcaccatgtggttcagcaaacgcctacctacg tttgttaatgtaccagaggaccacccccatattgaggttactagaatagatgggactgtg gacacacctccatgtctaaaggtgacacacaagacatatgggacccagaccagcaatgac gacatggtctgctgtcgtctaagcatgcctgttgaattcccttggaagatcactgatgtc agtgaggtgatcgctgaggaccaaaaagccaagaaggatgatggaggcaagattgattat ggcagcattacaaagtacttctactctgtgagagtgtttgctggacaagatccatcatct gtttgggtgggctgggtgacaccagactaccactactatagcaagcacttcagcctcagc acagttcgcactgtcactgtaacgctgggagacgagcggggacgtgttcatgagagtgtg agaaggagtaattgttacatggtctgcgctggggatgttgtcagcggctccacaggccgt agtaacactgatctggagattggctgctccatagatctggcctcaggcctggtctcattc actgccaatggcagagatctgcctactgcataccaggttgagcctaacactaagctcttc cctgctgtgtttgttcaacccacaagtcccaacctcttccagtttgagtttccaaaaatc ccagatgcaatgcccctgtcttcagccatctttaagagtttacaaagaaacccagagccc cagtgtcctcctcggctggatgtgcagacaatcgtgtccgtgttgtggagcagaatgccc aacaccttcctgtcggtggagacggcccgtgtgagtgagaggcatggctgggtggtgcag tgtctggagcccctgcagatgatggctgttcatatcccagaggagaacaggtgtatcgac atcatggaactatcagaaaacgaagatctacggcagttccactatcatactttaaaggtc ttctgcgccctttgtgcattgggcaacactcgcgttgctcacgccctctgtagccatctt gaccaatcgcagctcctgtataccattgataaccagtacctgtctggtcaactgcgtgaa ggcttttacgatgtcctcatcagcattcacctggagacgggcaaagaggcccatctcatg atgaacaatgagtttataatcccagtaacggatgagacgaggagcatccgcctcttccct gacgactctaagcgtcactctcttcctggcgtaggcttgagcacttcacttgcccctcgt ttcaacttcacccctccgtatttcattacccccaagcgcgatctgcctctcttcagccct cagatccctctgggtatcctgaaggagaaagccatcagtatgcttacggaagctgtgcag ggcggaggcgcccacattcgagatcctgtgggcggaagcgttgagtatcagtttgtgccg attctcaagctgatcggcaccctgctgataatgggtgcgatgaccagcgaggaggtgagg accatcctgcttctcattgaccccggcgtgtttggggatgggaaggaggaggaggagcaa acggcagtggcggaacagggagcggagaaagaggaggccgccagtaatgaagagaaggct gtggaggcaggggaggaggagagtaaagaggccaagcagtctcccaaaggtcttctagag aaaagcttgcctgagtcggtcaaacggcagatgtgtgaactgctgcactatttctgtgac tgtgagctgaagcagcgcattgaggctatagtggccttctcagatgattttgtgtccaag ctgcaattcaatcagaagttccgctacaatgagttgatgcaagccctcaacatgtcagct gctgtcactgccaagaagacaagagagtttcgctcacctccccaagtgcagataaacatg ttgctgaacttcagtgctggtgatgattgcacctgccctgaggagctgcaagaggagctt caaagcttccatgatgacctgcgactacattgtggaatccctatggaagaggaagaggag gagcaggacacatctcttaaaggccgcctaatgtccctggtatacaagattaaaggtcgt ccccaaaaaactgaggaaaaaccaacggagcaagaacaggctgctcctacaaacctgaag gagctgatatctcagactatggtcacctgggctcaggagtgcaagatccaagacccggca ctggtccgcagcatgttcagccttttgagaaggcagtatgatggcatcggtgagctgctc agggccttgaggaagagctacaccatcagtgccaaatctgtatgggacgcgataaacctg ctggcctcgctgggtcagatccgttcactacttagcgtccgcatgggggaagaggagggc cagcttatgatcgacggcctgggggacatcatgaacaacaaagtgttttaccagcatcca aatctgatgcgtgttcttggcatgcacgagacagtaatggaggtcatggtcaatgtgctg ggaggaggcaaggataaggagattgccttccccaagatggtggccagctgttgtcgcttc ctgtgctacttctgtcgcatcagccgtcagaaccagaaggctatgtttgaccacctgagc tacctcctggagaacagcagtgtggggctggcttgcccagccatgagaggctctacacct ttagatgtggctgcctcctctgtgatggacaacaacagtttagctctggcacttgaggaa cctgatcttgagaaggtggtgacatatctggcaggctgtggcttacagaactgcccaatg ctcattgccaggggatacccagacattggctggaacccaattgaaggagaacgttattta tccttcctacggtttgctgtctttgtcaattgtgaaagtgttgaagagaatgctaatgta gtggtgaagcttttgatcaggcgtccggagtgctttggacctgctctcagaggagaggga gggcaaggtttactcgctgccatgaaggaagccatcaagatctcagaagatcctgcttta gacctgcctaacttacccgagggggctgcacacaccgtcggagaggatgaagaggaggag gaggtcgcccacatgggcaactctattatgtctttctactcagcccttattgatcttctg ggccgctgtgcacctgagatgcatcttataaacaaaggcaaaggcgaagcactgcgtatc cgtgccatcctccgttccttagttcccatgaaagatttggtgggaattatcagtattcca ctcaaaatgccggtcgtcaataaagatggcaccgtgacagagccagatatgaatgccagc ttctgtccggagcatagggcacccatggtgcttttcctggaccgtgtctatggtattgac gaccagagcttcttgatgcacctgctggaggtgggcttcctgccagacctgcgagcatca gcctccctggactcggaggtgctcaggaccacagagacagctctggccatgaaccgctac attggatctgcagtgcttcctctgttgacccgctgtgctcatctgttcgctcacactgag cactatgcaacgctcgttgactctacgctgcacaccatctatcgcctctcaaagggccga tcacttaccaaggcccagagagatgctattgatgaatgtctactggccatttgcatgcat ctgaggccatcaatgctacagcaacttttacgtcgtcttgtgcttgatgttccacagctt acagagtactgcaagatgcccattaagctgttgaccaatcactatgagcagaactggaag tactactgtctgccaacaggcctgggcagctatggaatggcatcagaggaggaactccac ctcaccaagaaactcttctggggactttttgatgctctttctcaaaagaaatatgatgca gagcttttcaaaatggccatgccatgtctgagtgccatagctggtgccataccacctgat tatgttgactccagcccaggctccacattagttaagcaggcctctgtggatgcacaaggc aacttcgacccccagcctattagcactgcaaacatctcgctgcctgaaaagctagattac atagcaagcaagtttgctgcgcattcccatgagaaatggtcctctgagaagatcgctctc ggctggactgcgggagataaagtagatgacaaagctaaaactcatccacttctgaaaccg tacaaagcactgagtgaaaaggaaagggagacttaccgctatcctgtgaaagagactctg aagagcatgttggcaatgggatggaacattgagagagccaaagaaggagaggccatgttc cagcaaagggaatcagaaaaacagcgcaagatatcagagtcctctcagggtgagtttatt ccagccccacaagatttggaaaatgttattctatcaagagaactacaggcaatggttgaa acagttgcagaaaattaccacaacatttgggcaaagaagaagaaaaaggaacttgatagt aaaggaggaggaagtcatccattgttggtaccgtacgacacactgacggcaaaggagaag tacagagatcgagagaaggcccaagaactctttaaattcctgcaggtcaatggatatgcc atcagcagaggtctgaaggacatggagcaggattcctcttctatggaaaagaggattgcc tataagttcctcaagaggctcttgaattatgtcgattctgcacaggagtttatcgcccat cttgaggctttggctaccagtgggaagacagaaaaatctccccatgatcaagagatcaag ttctttgctaaggttctgctgcccctcatagaccagtacttcaaaaaccactgcttgtac ttcctgtcatctcccaatatcagcctgagcagcagtggctacgcatctaacaaagagaag gagatgatcaccagtctattctgtaagctggcagcccttgtcagacatagaatatcactc tttggaagtgactccaccaccatggtgagctgcttgcacatcctgtcacgctcactggac ttcaggactgtgatgaagtctggctcagagctggtgaaggctggtgtcaggacgttcttt gagaatgctgcagaagacctagagaagacactggagaacttgaagctggggaagatgggt cagtcacgcacccagatgaagggcgttacccagatcatcagctacacctcagcggccctg ctgcccatcctgacggttctctttcagcatatcacccaacaccagtttggagtagagctg ctattggatgacattcagctgtcctgctaccgcatcctgaccagcctctactctttgggc actggcaagaacatctatgtggaaaaacagcttccagtgctgggtgaatgtttatccaca ctggttggagccatgcctgttgccttcctggaaccccacctaaatatgcacaacccccaa tctgtcttcaacaccaagacaccaagagaacgagctattttgagcatgccagacactgtg gatgagatgtgtcttgagatgccccatctggatggcctgatgaaggacattggtgacatt tctgaatctggagcacgctacacagagatgccacaggtcatcgaggtcatcctgccaatg ttgtgtaactacctgtcttactggtgggcaaaaggcccagaaaactccccagttgatacc aattgctgcacaactgtcacatctgagcatctcagcctaatcctgggcaatatccttaag attctcaataacaaccttggcattgataacgccccttggatgaaaagacttgcagtatat agccagcctatcattagcaaggctagcccagatcttcttagaatgcacttcctgcctaca ctggagaaactgaagaagaagacagtgaagatagtggctgaggaggagctgctgagggct gaaagcaggacagacactcaggaagctgaactgcagattctggatgagtttgctgttctc tgcagggatctgtatgccttctatccaatgctcattcgttatgtggacaacaacagatcc aaatggctgaagcaaccagattcagattcaactgaacttttcaaaatggtgtcagagatt ttcatcctttggtgtaaatctcataactttaaaagggaagagcaaaattttgtggtgcaa aatgaaattaacaacctggcgttcctcactggagacagcaagacgaagatgtcaaaatct ggagatgatgagtctggaggtcaggaccaagacagaagaggaaaaaggagaaaaggagag ttgtactccattcagacttcccttatcgtagcagctcacaagaagatgctgcccattggt ctgaacatgtgcactcctggagaccaggagcttatttcccttgccaaaatccgttatagt ctgaaagacacagatgatgaggttaaggattacctgaggaagaacctccatcttcaggag aagtcagcagatccagcagtgcagtggcaggtgaacctctatagagatgttgtggtgaag aatgagggacctccagaccaagagcataatgtggagagagttcaatccatctccgctgct gtctaccaccttgatcaggttgaacagccgctgaggaacaagaagatggtgtttcaaaag ctgctgtcaaagcaaagaaagcgtgccgtggtggcctgtttccgcatggcaccactctac aacttaccaaggcatcgctcgattaacctcttcctcagtggctatcagagactttggata gagacagaggagtactcctttgaggagaagctagtgcaggacttggcaaaaactcccatg actgtggtagaggaagaagaggaagaagaagctgcagttcagccagaccctcttcatcag ctcatccttcacttcagtcacaatgctctgacggagagaagttttctagaagaggatcct ctctacattgcatatgctgacatgatggcgaagagctgtgccgagaatgaggaagaagaa gaggaagaggagggaaaagaaaaaacatttgaggaaaaagaaatggagaagcagaagatt ctgtaccagcaggccagacttcacgcccgaggggctgctgagatggtgctacagatgatc agtgccagtaaaggccgacttggtcctatggtgactggcacccttaaattgggcatttct atcctaaatggaggcaacgttcttgtccagcagaaaatgctggattatttgaaggaaaaa cgagatgcgggcttctttaaaagtttatccggactaatgatgtcttgcagtgtgctggat ttaaatgcatttgaaaggcaaaataaggcagagagtcttggaatggtgactgacgagggg tcaatcaacgtgaaagagaggggttccaaagtactacaaaatgatgactttacaaaggat ctgtttagatttttgcaacttctatgcgaggggcacaataatgatttccaaaacttcttg cggacccagagtggaaacactactacagtcaacatcatcattagcactgtggactaccta ttacgtctacaggaatctataagtgatttctactggtattactctgggaaagatatcatg gatgaggctggccaacttaacttctccaaagctttggcagtagccaaacaaatctttaac tcactcactgagtacattcagggcccttgtatagggaatcagcaaagtttggcacacagc aggttgtgggacgcagtggtcgggttcctgcatgttttcgcaaacatgcaaatgaaactg tcacaggattctagtcaaatcgagttattgaaagagctgatggatttgcagaaagatatg gtggtcatgatgttatctcttctggagggtaatgtggtgaatggaactatcggcaagcag atggttgacacattagtggagtcctccagcaatgtggaaatgatcctcaagttcttcgac atgttcctcaaactgaaggacctcactacatctgataactttaaggagtacgacccagat tgcaaaggcgttatatccaagaaggagttccagaagtctatggatagccaaaagcaatac acacagtctgagatcgagtttctcctctcctgtgtggaggccgatgaaaatgatatgttc aactacaaggagtttgtggaacgcttccatgaaccagccaaggacatcggcttcaacgtg gctgtgcttcttactaacctttcagaacacatgcctcacgactcacgcttgtccaccttc ttagacctggctgaaagcgttctcagttactttgagccatacctgggccgtattgagatc atagggggtgccaagaggattgagagggtttactttgagatcagcgagtctagcagaacc caatgggaaaagcctcaggtcaaagagtccaaacggcaattcatcttcgatgtggtcaac gaaggcggtgagagtgagaagatggagttatttgtgaacttctgtgaggacaccatcttt gagatgcagttggcctctcagatctctgagccagacgccgcagaacgacccgaggaggac gaagacgaggagttgcatagtctgcttgaaggattgtctgagaaggaagactcatctctt gagtccgcctcggccttcactgcagcctgcgcttctgtgaagaagagcatgtctaatttc cgtaaaatgctgacgtttaagagtatgaggaaacagttgaaaaaattcaggaaacttacc atcagggaaatgatcacagggttcttctccttcttctggatgctcttcactgggttcttc aaaggcattttcgccatcatcttcgggttctttcatattatttggtcctccatgtttgga gggggtcttgtggagggtgctaaaaacatgaaagtgacagatatcttgggtaacatgcct gatccaacacagtttgggatccatggtgatgtaatggaagcagaaaaatcagagagcagc gaattggtggtgtctgcagatatggtgcagatgactggtgctggtgctgagaagctggaa acggatatgatcatggatctacttaatccagctgtgaagaaggaggggaagcatgtggca gaacttggtctgggtgatgtctgtgaggtcctgacagagtctagctcccctgttgagaaa aagaagagccagaaagtagcagcagagaagccagaatccgagccagagaaagctgacact gagaatcaagagaaagaagacaaggctaaagaggaaactcctgaggaaccagcagcagca aaaccagctccaaaagccaaacgtggctcagcaaaggaagaagctccagcatttatggcc agcttctttgcagggcttgaagtctacaaagccaaaatgctgaactacctggctcgcaat ttctacaaccttcgtcttctggccttgtttgtggtcttcgccattaacttcatcctgctc ttctacaaggtgactggagaattcgatgatgaggaagaggagggatcctggggtggtgaa gaggaggaaggtgatgaagatgatgaaggaatggaatacttcattcttcaggagaacact ggctacatggcacccacattgacgttcttggctgtactgcacacgatcatctccttactc tgtgttgttggatattactgccttaaggttcctttagttgtgttcaagcgggagaaggag atcgccaggaagcttgagtttgatggcttgtatattaccgagcagccgtctgatgatgac atcaaaggacagtgggatcgtttggtcattgcaactccgtccttccctaacaattactgg gacaaatttattaagaggaaggtcatcaataaatatggtgacttgtacggggccgagcgc atagctgaactcctgggtctggataagagtgctctggactttgatcccactgaagaggcc gtggtgaaggaggcctccctgctgtcctggttgagctcaattgataccaagtaccacatc tggaaaatgggggtggtgctgacggacaactcttacctctacctgatctggtacaccacc atgtctattctgggacattacaataacttcttctttgccgctcatttgctggacattgcc atgggtgtcaagacactgaggaccatcctctcttctgtgactcacaatggcaaacagctg gtattgactgtgggcctcctggcggttgtggtctacctgtacaccgtggtggcttttaac ttcttccgcaagttctacaacaaaagcgaggatgaggacgcacctgacatgaaatgtgat gatatgatgacttgctacctgttccacatgtacgtgggtgtgagagctggcggtggcatc ggtgatgaaatcgtggaccctgcaggcgacccgtctgagctctaccgcattctgtttgac atcaccttcttcttcttcgtcatcgtcatcctgctggccatcattcagggtttgatcatt gatgccttcggtgagttgagagaccagcaggagcaggtgaaagaagacatggagacaaaa tgcttcatctgtggaatcgggaatgactattttgacacaaccccgcatggctttgagacc cataccttacaagagcacaatctggccaactatttattcttcctgatgtatcttatcaac aaagatgagactgaatacactggtcaggagtcgtatgtttggaagatgtatcaggagaga tgctgggatttcttccctgctggagactgtttccggaagcaatacgaggaccagctgggc tag

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