Sinocyclocheilus anshuiensis: 107678700 Help Entry 107678700         CDS       T04917                                  Name (RefSeq) ryanodine receptor 3-like   KO K04963   ryanodine receptor 3 Organism sanh  Sinocyclocheilus anshuiensis Pathway sanh04020   Calcium signaling pathway sanh04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:sanh00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     107678700    04020 Calcium signaling pathway     107678700  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:sanh04040]     107678700 Ion channels [BR:sanh04040]  Voltage-gated cation channels   Ryanodine receptor    107678700 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 Ins145_P3_rec SPRY MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_8 Motif Other DBs NCBI-GeneID:  107678700 NCBI-ProteinID:  XP_016329558 LinkDB All DBs Position Unknown AA seq 5003 aa AA seqDB search MAEGGGDAEDEIQFLRTDDEVVLQCVACIQKENRKFCLSAEGLGNRLCYLEPTSEAKYVP PDLCICSFVLEQSLSVRALQEMLAKTGQNNDQFIRKAAQSGGHRTLLYGHAVLLRHSFSR MYLTCLKTSRSMTDKLSFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRIGDDLILVSVS SERYLHLSISNGSIQVDASFMQTLWNVHPTCSGSNVEEGYLLGGHVMRLFHGHDEVLTIP GSDQSEEEQRLVNYETGKAGAKARSLWRLEPLRISWCGSHIRWGQPFRLRHLTTGHYLAL TEDRGVVLQDRERSDTTFTAFCFRASKEKLECSPKRDIEGMGVAEIKYGDSLCFLMHVAT GLWLSFQAPDVKSARLGPLKRRVCLHSEGHMDDGLTLQRCQHEESRAARIIRNTTRLFSC FIRELDGLSAKNRSSVVLPIDEVLQTLNDLIAYFRLPDAELEHEKKQIKLRSLKNRQNLF KQEGMLSLVSSCIDRLSVYNSAAHFGECASEEAGAAWKDILNLLYELLAALIRGNRNNCT QFSHNLDWLVSKLERLESSSGILEVLHCILIESPEALNIIQRGHIKTIISLLYKHGRNHK ILDVLCSLCVCNGVAVRANQNLICDHLMPRRDLLLQTRLVNDVQSMRPNIFVGVSEGSAQ YRKWYFELVIDHVDHFLTAEPSHLRVGWASTKGYAPYPGGGEGWGGNGVGDDLYSYGFDG LHLWSGRIPRTVASMKQHLLASDDVLSCCMDLNAPSISFRINGQPVQGMFENFNIDELFF PVVSFSAGVKVRFLLGGRHGDFKFLPPSGYAPCYEALLPKEKMRVEPVKEYKRDADGVRD LLGNTHFMSQTSFIPKPVDTSQIAMPPHLEKVRDRLAENIHELWGMNKIELGWCYGKRIR EDNKRQHPCLVDFSKLPETERNYNLQMSTETLKTLLALGCHVVQVKVNAEEELKKLKLPK NYMMSNGYKPSPLDLSDVKLSAAQELLVDKLAENAHNVWAKDRIKQGWTYGIQQDVKSKR NPRLVPYALLDERTKKSNRDSLREAIRTLIGYGYSVEPPDQDAGHVVERLSIDKIRFFRV ERTYAVRTGRWYFEFEAVTGGDMRVGWARPGCKPDVELGTDEQAYVFDGHRGHRLHTGSR LFGRCWHAGDVVGCMINLEDKSMIFTLNGEILITNKGSELCFADFDIDDGFIPVCSLGLS QVGRMNLGKDASTFKYYTMCGLQEGFEPFAVNMNREVTMWFSKRLPTFCNVPKDHHHIAV TRIDGTVDGPPCLKVTHKTFGTQNSNADMVFCRLSMPVEFHSSFRSSSCTHINGLSEDEP LKLRHRHPVKSTKHSDEGRRTDYSSITTYYHSVRIFAGQDPSCVWVGWVSPDYHYYSNHF SLSKNRTVTVTLGDERGRVHESVKRSNCYMVWGGDVTSAAHASGRSNVDLEIGCLIDLAM GLLAFTVNGKELPRSYQVEPSTKLFPAVFVRPTSSSLFQFELAKIKNAMPISSAIFKSEH KNPVPQCPPRLDVQTINSVLWSRMPNTFLKVETARVSERHGWMVQCVEALQMLAVHIPEE NWCVDIMELSEQEELRKFHYHTLKLYCALCAHGNTRVAHALCSHLDQSQLLYAIDNQYLS GMLREGFYDVLISVHLETARAARRMMNNEFIIPVTAETRSIRLFPDASKQHQPPGVGLST CLKPRLSFGPPCFISSKREQHLYSPEIPLEVLKERAIRMLTEAVQGGGDHIRDPVGGSVE FQFVPILRLIGALLTMGVLTSRDVHKILLLIEPGVFSEHRDDGAKEGLTGAEEKAVEAGE EEEARDGKELVKSLLEKKLPESVKRQMCELLHYFCDCELRHRVEAIVSFSDSFVSKLQVN QKFRYNELMLALNMSAAVTAKKTREFRSPPQEQINMLLNFTVGEDCPCPADIQDELYDFH GELRLHCGIPVEEDEEDQDSSIKARLLALVYKIKGQPQRSEREPTKKEQSAPSNLKELIS QTMVSWAQETHIQDPELVRLMFSLLRRQYDSIGELLRATRKTYTISAVSVHDTIHLLASL GQIRSLLSVRMGKEEEQLMIHGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGGGK SQEIAFPKMVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASPSMRGSTPLDVA ASSVMDNNGLALALEEPDLDKVVTYLAGCGLQSCPMLLAKGYPDIGWNPIEGERYLSFLR FAVFVNGESVEENSSVVVKLLIRRPECFGPALRGEGGNGLLAAMKEAIKISENPSLDLPS TGPAYASDVSTEGEQEEEVVHMGNAILSFYSALIDLLGRCAPEMHLINKGKGEALRIRAI LRSLVPTEDLVGIISIPLKMPVVNKDGSVFEPDMSATFCPDHKAPMVLFLERVYGIEDQS FLLHLLEVGFLPDLRAAASLDTEALRTTETALAMNRYIGSAVLPLLTRCAPHFSGTEHHA ALIDSTLYTVYRLSKGCSLTKAQRDAIEECLLAICKYLRPSMLQHLLRRLVFDVPLLSEY CKMPLKLLTNHYEQNWKYYCLPSGWGSYGQASEEELLLTKKIFWGIFDSLSQKKYEQDLF KMAMPCLSAISGALPPDYIDFTLSTTLEKQVSVDTQGNFDPRPVNTATICLPEKLEYIAN KYAEHSHEKWAAEKVLLGWKHGENIDEKAKTHPMLRSYKSLTEKEKEMYRWTVRESLKSM LAMGWSIDRTREGESVFQQREMEKMRRVSQASQGNGFNPNPLDMSSVLLSRELQSMVEVV AENYHNIWAKKKKSDLCSRATGGAHPLLVPYDTLTTKEKTKHRERAQDLFRFLQINGYAI SRGLKDMEQDSSSMEKRFAFRFLKKLLKYVDSAQEFIAHLEAMATSGKNDRSPHEQEIKF FAKVLLPLIDQYFKNHSLYFLSSPTKNLSSSGYASNKEKEMVTSLFCKLATLVRHRISLF GSDSTTIVSCLHILAHTLDTRTVMKSGSELVKAGLRTFFESAAEDLEKTLENLKLGKFTH SRSQMKGVSQNINYTTVALLPILTALFEHITEHQFGSDLLLDDVQVSCYRILTSLYSLGT GKNIYVERQLPALGECLATLAGAMPVAFLEPQLNTHNPCSVFNTKTSRERALVGLPESVE DVCPEMPRLDGLMKDINDMSESGARYTEMPHVIEVVLPMLCNYLSYWWERGPENRPAGVC SSTVTSEHLSLILGNILKILNSNLGIDEASWMKRIAVYAQPIISKARADLLKTHFLPTLE KLKKKTVKVVSEEELLKADGKGDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRSRW LKEPDADSSDLFRMVAEIFILWCKSHNFKREEQNFVVQNEINNLSFLTGDSKTKMAKSFL PKAGGQDQERKHKKRRGDFYSIQTSLIVAALKKMLPIGLNMCTPGDQELILLAKMRYGLK ETDEEVKEHIRQNLHLQEKSADPAVQWQLNLYKDVMTKTEDTLDPERSIERIQSISAAVF HLEQVEQPLRSKKCVWQKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFLTGYQRLWIEA EMYSFEEKLVQDLAKTQPKTDEEEEEITDTQPDPLHQLILHFSHNALTERSSLEEDQLYI AYADMMAKSCAENEEEDEEGKEKTFEEKEMEKQKTLYQQARLHDRGAAEMVLQMISASKG RLGPMVTFTLKLGISILNGGNITVQQKMLDYLKEKRDVGFFKSLSGLMQSCSVLDLNAFE RQNKAEGLGMVTEEGSINVRERGSKVLQNDEFTKDLFRFLQLLCEGHNNDFQNFLRTQTG NTTTVNIIISTVDYLLRLQESISDFYWYYSGKDVMDEAGQRNFSKALAVAKQIFNSLTEY IQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDSSQIELLKELMDLQKDMIVMML SLLEGNVVNGTIGKQMVDTLVESSSNVEMILKFFDMFLKLKDLTTSENFKEHDPDRKGVI SKKEFQKSMENQKQYSQSEIEFLLSCAEADENDMFNYEEFVKRFHEPAKDIGFNVAVLLT NLSEHMPHDSRLSTFLNLAESVVNYFEPYLGRIEIMGGGKRIERVYFEISESSRTQWEKP QVKESKRQFIFDVVNKGGESEKMELFVNFCEDTIFEMQLASLISEPDAAERQEEDDDEDD TRSVDLDEDDEDSAQESSSAFALACVSMRKSLSNLRQLLTFRSMRRQYRKLRKMSVREMI RGFFFFFWMIFTGMFRFLYGLVWGFFHILWSTLFGGGLVEGAKNMKVTDILGNMPDPTQF GIHGDVLELEKLEYCDVSSVAELGRMAAGDQAEMDLMTELMYMQPRREGGKHGMEPGLGD MSEVIGVDAPSLASAVHQKKAQEAASKQSAESETKSESEKADVEDGEKKDQHKGKEESVS DEKKPLKKRRGQRKQQAEAFMAAFLAGLDIHQTKTLNYLARNFYNLRFLALFVAFAINFI LLFYKVTGEDSDDLDPWTRREEEEEDEGVLEYFVLQESTGYMAPTLRFLAVMHTVISFLC VLGYYYLKVPLVVFKREKEIARKLEFDGLYITEQPSDDDIKGQWDRLVINTPSFPNNYWD KFVKRKVINKYGDLYGAERIAELLGLDKSALDFNPTEETVIKDASLLSWLSSIDTKYHVW KMGVVFTDNSFLYLVWYTTMSILGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLV LTVGLLAVVVYLYTVVAFNFFRKFYNKSADEDEPDMKCDDMMTCYLFHMYVGVRAGGGIG DEIEDPAGDPYELYRILFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKC FICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQRLDSMMPKARVF VRVFTLPRIPCLLARRELKPSSSALPPSHLSYATPAFPPDVVEVDCNVEHGSSQQRFTNF CQLKPFEILSFNNLASHSHVYGSLIKWRQSGCSSVQTERSQQKEQRLQKGLNDTMEKLNA IPDASAAVIRGEAAEGLTGVLLC NT seq 15012 nt NT seq  +upstreamnt  +downstreamnt atggctgaaggcggaggagacgcggaggatgagattcagtttctgcgcacggacgatgag gtggttctgcagtgtgtggcctgcattcagaaggagaaccgcaagttctgcctgagcgct gagggtttggggaaccgcctgtgttacctggagcccacgtcagaggccaagtatgttcct ccagatctgtgcatctgtagttttgtgctggagcagtcgctgtctgtccgcgcgctgcag gagatgctcgccaaaaccggacaaaacaacgaccagttcattagaaaggcggctcagagc ggaggacaccggacgttactgtacggtcacgctgtgctcctcagacactccttcagcagg atgtatctgacctgtttgaagacgtcgcgctcgatgacggataaactgtcgttcgatgtg ggacttcaggaagactcgacaggtgaggcctgctggtggaccattcatcccgcgtctaaa cagagatcagagggggagaaggtgcgtatcggagatgatctcatactcgtcagcgtctca tcggagcgatatctgcatctgtccatatccaacggcagcatccaggtggatgcatccttc atgcaaacgctgtggaatgtccatcccacctgttcagggagcaacgtggaggaaggatac cttcttggcggtcatgtgatgcgtctctttcacgggcacgacgaggttctgacgatcccg ggatctgatcagagtgaagaagagcagagattggtgaactatgagacgggtaaagccgga gcaaaagcccgatctctctggaggctggagccgttacgcatcagttggtgtggcagtcac atccgctggggtcagccgttccgtttgcgtcacctgaccaccggtcactatctggcactt acggaggaccgaggcgtcgtgctgcaggacagagagagatcagacaccacgttcacagcc ttctgcttcagagcctccaaggagaagctggagtgcagtccgaagcgggacatcgagggg atgggagtggcggagatcaaatacggagattctctgtgcttcttgatgcacgtggcgacg ggtctctggctgtcctttcaggcgccggatgtcaaatccgctcgactcgggccgctcaaa cgccgggtgtgtcttcattcagaaggacacatggatgatggtttgacgttacagcgctgt caacacgaggagtcgagagccgctcgaatcatccgcaacaccacgcgactcttcagctgc ttcatcagagagctcgacggtttgagcgccaagaaccgctcgtctgtggttctgcccatc gacgaggttctccagacgctcaacgacctgatcgcgtacttcagacttcccgacgccgag ctggagcacgagaagaaacagatcaagctgcgctccctgaagaaccgacagaacctcttc aagcaggaggggatgctgtctctggtgtccagctgcatcgaccgcttgagcgtttataac agcgcggctcatttcggtgagtgtgcgagtgaagaggccggagccgcgtggaaagacatt cttaacctgctctacgagctgctggccgctctcatccgcgggaaccggaacaactgcaca cagttctcacacaacctggactggctggtcagcaaactcgagagactggagtcgtcttca gggatcttggaggttcttcactgtattctgattgaaagtccagaagctctgaacatcatc cagagaggacacatcaagacaatcatctctctgctctacaaacacggacgcaaccacaag atcctggatgtcctctgctctctgtgtgtgtgtaacggagtcgctgtcagagccaatcag aacctgatctgtgatcacctgatgcccagacgagacttgctgctgcagacgcgattggtc aacgacgtccagagcatgaggcccaatatcttcgtgggagtcagcgaaggctcggcccag tacaggaagtggtattttgagctggtgattgatcatgtggatcacttcctgacggccgag ccgtcgcacctgcgggtgggctgggcgtccactaaaggttacgctccctacccgggcggc ggagagggctgggggggcaacggcgtcggggatgatctctactcctatggcttcgatgga ctgcacctgtggtcaggacgcatcccgaggacggtggcgtctatgaagcaacatctgctg gcgtctgatgacgtgttgagctgctgcatggatctgaacgctcccagcatctccttcagg atcaacgggcagccggtgcagggcatgttcgagaacttcaacatcgacgagctcttcttc cccgtcgtcagcttctccgccggcgtcaaggtgcgcttcctgttgggcggtcgtcacgga gacttcaagttcctgccgccgtcgggttacgcgccgtgttacgaggctctgctgcccaaa gagaagatgagggtcgagccggtcaaagaatacaagagagacgcggacggagtgagagac ttactgggaaacacacacttcatgtcacagacctccttcatacccaaacctgtggacacg tctcagatcgcgatgcctcctcatctggagaaggttcgagatcgtctggcggagaacatc catgagctctggggaatgaacaagatcgagctgggctggtgctacgggaagaggatcaga gaggataacaagcggcagcacccatgtctggtggatttctccaaactgccagaaaccgag aggaactacaacctgcagatgtccaccgaaacactcaagactctgctggcgttgggctgt catgtggtccaggtgaaggtcaacgctgaagaggagctgaagaagctcaagctccctaag aattatatgatgtctaacggctacaagccgtcgccgctggatctgtcagacgtcaaactg agcgccgctcaagagctgctggtggacaaactggcagaaaacgctcataacgtctgggcc aaagaccgcatcaaacagggctggacctacggcatccagcaggatgtgaagagcaagcga aaccctcgtctggttccgtacgctttactcgacgagcgcaccaagaaatcgaaccgcgac agccttcgggaagccattcgcacgctgatcggatacggatacagcgtcgagccgcccgac caggacgccggtcacgtggtggagcggctgagcatcgataagatccgtttcttccgcgtg gagcgcacgtacgcggtgaggacgggccggtggtatttcgagtttgaggcggtgacaggt ggagacatgcgggtgggctgggctcggcccggctgcaaacccgacgtggagctgggaacg gacgagcaggcctacgtcttcgacggtcatcggggtcatcggctccacacgggcagccgt ctgttcggccgctgctggcacgccggggatgttgtgggttgtatgatcaacttggaggac aaatccatgatcttcaccctgaacggagaaatcctgatcaccaacaagggctctgagctg tgcttcgccgactttgacattgacgacggtttcatcccggtctgtagtttgggtctgtct caggtgggccgtatgaatctggggaaggacgccagcacctttaagtactacaccatgtgt ggcctgcaggagggcttcgagcccttcgccgtcaacatgaaccgcgaggtgaccatgtgg ttcagcaaacgcctgcccaccttctgcaacgtgcccaaagaccaccatcacatcgcggtc actcggatcgacgggacggtggacggtccgccgtgtctcaaagtcacccataagacgttc gggacgcagaacagtaatgctgacatggtgttctgcagactcagcatgccggtggagttt cactccagcttcaggagcagctcttgcacgcacatcaacggcctgagtgaggacgagccg cttaagctcagacacaggcatccagtgaagtccaccaaacactcggatgaaggcaggaga acagattacagcagcatcaccacatactatcattcggtcaggatatttgcgggtcaggac ccatcctgcgtgtgggtcggatgggtatcccctgactaccattactatagcaaccacttc agcctcagcaagaaccgcacagtgaccgttaccctgggagacgagcggggccgcgtgcac gagagcgtgaagaggagtaactgttacatggtgtggggtggagacgtcaccagcgccgcc cacgcgtccggccgcagcaacgtggatttagagatcggatgcctcatcgatttggccatg ggtctgttagcattcaccgtcaatggcaaagagcttcccagatcataccaggtggagccc agcacaaaactctttcctgctgtgtttgtgcggcccacaagctcaagtctcttccagttt gaactggccaaaatcaagaacgccatgcccatctcgtcggccatctttaagagcgaacac aagaatcccgttcctcagtgtcctccacgactggacgtccagaccattaactcggtgctg tggagccgaatgcccaacaccttcctgaaggtggagacggcccgtgtcagtgagaggcac ggatggatggtccagtgtgtggaagcgctgcagatgctggctgtacacatccccgaggag aactggtgtgtggacatcatggagctgtcggagcaggaggagctgcgtaagttccactat cacacgctgaagctgtactgcgctctgtgtgctcacgggaacacacgtgtggctcacgcg ctctgcagccacctcgaccaatcgcagctgctctacgccatcgacaaccagtacctgtcg gggatgctgcgcgagggcttttacgacgtcctcatcagcgtgcacctggagacagccaga gctgcccgccgcatgatgaacaatgagttcatcatccccgtcacggccgagacgcgcagc atccgcctcttccccgacgcctccaaacagcaccagcctccaggcgtcgggctcagcacg tgcctcaaacccagactcagcttcggcccgccgtgcttcatcagcagcaagcgcgagcag cacctgtacagcccagagatcccgctggaggtgctaaaggagagggccatccgcatgctg acggaggctgtgcagggtggaggagaccacatccgcgaccccgtgggcggaagcgtggag ttccagttcgtgccgattctgcggctcatcggtgcgctgctcaccatgggagtcctgacc agccgcgacgtgcacaagatcctgctgctcatcgagcccggagtgttcagcgagcacagg gacgacggcgccaaagaggggctgacgggagccgaggagaaggcggtggaggccggagag gaggaggaggccagagatgggaaagagctggtgaagagtctgctggagaagaaactcccc gagtctgtcaaacgacagatgtgtgagctgctgcactatttctgcgactgtgagctgagg catcgcgtcgaggccatcgtctcgttctccgacagcttcgtctctaagctgcaggtcaat cagaagttccgctataacgagctgatgctggcgctcaacatgtcggccgccgtcaccgcc aaaaagaccagagagtttcgctcgccgccgcaggaacagattaacatgctgctgaacttc accgtgggcgaggactgtccgtgtcccgcagacattcaggacgagctgtacgacttccac ggcgagttgcggctgcactgcgggattccagtggaggaggatgaggaggatcaggactcg tctattaaagctcgtctgctcgctctcgtctataagatcaaaggtcaaccacagagatct gagcgcgagcccacaaagaaagaacagagcgctccctcgaatctgaaggagctgatctct cagacgatggtgagctgggctcaggagacgcacatccaggacccggagctggtgcggctg atgttcagtctgctgagacggcagtacgacagcatcggagagctgctccgagccacgagg aagacctacaccatcagcgccgtctccgtccatgacaccatccacctgctggcgtctctg ggccagatccgctcgctactcagcgtccgcatggggaaggaggaggagcagctgatgatc cacggcctcggggacatcatgaataataaggtcttctaccagcatcctaacctgatgcgt gttctggggatgcacgagaccgtgatggaggtgatggtgaacgtcttgggaggaggaaag tctcaggaaatcgccttccctaagatggtggcgagctgctgccgcttcctgtgctacttc tgtcgcatcagccgtcagaaccagaaggccatgtttgatcacctgagctacctgctggag aacagcagcgtgggattggcatctccgtccatgagaggatccactcctttagatgtggcg gcttcatcggtgatggacaacaacggtctggcgctggcgctcgaggagcccgacctggac aaggtcgtgacgtatctggccggctgcggtctgcagagctgtccgatgctcctggccaag ggatatccagacatcggctggaaccctatcgagggtgagcgttacctgtccttcctgcga ttcgccgtgtttgtcaatggtgagagcgtggaggagaactctagtgtggtggtgaagctc ctgattcgtcggcccgagtgtttcggtcctgctctgcgaggagaaggaggaaacggactg ctggcggcaatgaaggaggccatcaagatctcagagaaccccagcctggatctgcccagc actggaccggcttacgcttcagacgtctccactgagggcgagcaggaagaggaagtggtt cacatgggaaacgccatcctgtccttctactcggctctgatcgatctgctgggccgctgc gctcccgagatgcacctgatcaataagggtaaaggtgaagctctgaggattcgtgccatc cttcgctctctcgttcccacggaggatctggtcggcatcatcagcatccctctcaagatg cctgtcgtcaataaagacggcagcgtgtttgagcctgacatgtcggccactttctgcccg gaccacaaggccccgatggtgctgttcctggagcgcgtgtacggcatcgaggaccagagc ttcctgctgcatctgttagaggtgggcttcctgccggacctgagagccgccgcctcactg gacacggaggctttgcgcaccacagaaacggctctggctatgaacaggtacatcggttcg gcggtgctgcctctgctgacccgctgcgctcctcatttctccggcacagagcatcacgcc gcgctcatcgactccacgctctacaccgtctaccgcctgtccaagggctgttcgctcacc aaagcccagcgcgacgccatcgaggagtgtctgctggccatctgcaagtacctcagaccc tccatgctccagcatctgctgcgccggctggtgtttgacgtgccgttgttgtctgaatac tgtaagatgcctctgaagctgttgacgaatcattacgagcagaactggaagtattactgt ctgccgtctggatgggggagttacggtcaggcgtctgaggaggagctgctgctcaccaag aagatcttctggggaatctttgactctctgtctcagaagaagtacgagcaggatctgttt aagatggccatgccgtgtttgagtgccatctctggagctctaccgccggattacatcgac ttcacactcagcaccacgttggagaagcaggtgtctgtcgacacgcagggaaacttcgac cccagacccgtaaacacagccaccatctgcctgccggagaagctggagtacatcgcaaac aaatacgctgaacattcccatgagaaatgggctgctgagaaggtgcttctgggctggaaa cacggagaaaacatcgacgagaaagcaaaaactcacccaatgctgagatcctacaagtcc ctgacggagaaggagaaggagatgtatcgctggacggtgcgcgagtccttgaagagcatg ttagcgatgggctggagcatcgaccgcaccagagaaggagagagcgtatttcagcagaga gagatggagaagatgcgccgcgtctcacaggcctctcaggggaacggctttaatccaaac ccgctggacatgagcagcgtccttctgtccagagaactgcagtcaatggttgaggtcgtg gctgaaaactatcacaacatctgggccaagaagaagaagagtgatctgtgcagcagagcc acaggaggagctcatccgctgctggtgccctacgacacgctcacgaccaaagagaagact aaacaccgagagcgagcgcaggatctcttccgcttcctgcagatcaacggatacgccatc agcaggggtctgaaggacatggagcaggactcgtcctcgatggagaaacgcttcgccttc cgcttcctgaagaagctgcttaagtacgtggactcggcgcaggagttcatcgctcacctc gaggcgatggcgaccagcggaaagaatgacagatcgccacatgaacaggaaatcaagttc tttgctaaggtgctcctccccctcatagaccagtactttaaaaaccactcgctctacttc ctgtcgtcgcccactaagaatctgagcagcagcggatacgcgtcgaacaaagagaaggag atggtcaccagtctgttctgtaagctggccactctggttagacacaggatctctctgttt ggaagtgactccaccactatagtcagctgtctgcacatcctcgcacacacgctggacacc aggaccgtgatgaagtccggatcggagctggtcaaagccggtctcaggacgttctttgag agcgcggctgaagatctggagaagaccctggagaacctgaagctggggaagttcacgcac tcacgcagtcagatgaagggcgtctcgcagaacatcaactacaccacagtggctctgctg cccatcctcaccgctctgttcgagcatatcactgaacaccagttcggctcggacctgctg ctggatgatgtgcaggtgtcgtgttatcggatcctgaccagtttatactcgctggggacg gggaagaacatctatgtggagaggcagctgccggcgctgggtgagtgtttggcgactcta gccggtgcgatgcccgtggcgtttctggagccacagctaaacacacacaacccctgctcc gtcttcaacaccaagacgtctcgagaacgagccctcgtagggctgccggagtcggtggag gacgtgtgtcctgagatgcctcgtctggacggtctgatgaaggacattaacgacatgtca gagtccggcgctcgttacacagagatgccgcacgtcatcgaggtggtgctgcccatgctg tgtaattatctgtcctactggtgggagagaggcccggagaaccggcccgcgggcgtctgc agcagcaccgtcacctccgaacacctcagcctcatcctcggcaacatcctcaagatcctc aacagcaacctgggcatcgacgaggcctcctggatgaagcgcatcgcagtgtacgctcag cccatcatcagtaaggcacgcgccgatctgctgaagacgcacttcttgccgacgctggag aagctgaagaagaagacggtgaaggtggtgtcggaggaggagcttctgaaagctgatggg aagggcgacacccaggaggcggagcttctgatcctggatgagtttgcagtgctgtgcaga gatctgtacgccttctaccccatgctcatccgctacgtggacaacaacaggtctcggtgg ttaaaggagccggatgcggattccagtgatctcttcaggatggtggcagagatcttcatc ctgtggtgtaaatcacacaacttcaagagagaagagcagaactttgtggttcagaacgag atcaacaacctctcgttcctcaccggcgacagtaaaaccaagatggcaaagtcattcctc cccaaggctggaggtcaggatcaggagcggaagcataagaagcgtcgtggagacttttac tccattcagacgtctctgatcgtggcggcgctgaagaagatgctgcccatcggtctgaac atgtgcacgccgggagaccaggagctcatcctgctggccaagatgcgatacggcctgaag gaaacagatgaagaggtgaaggagcacatcagacagaacctgcacctgcaggagaagtct gcagatccagccgttcagtggcagctcaacctctataaggatgtgatgacgaagacggag gacactctggacccggagcggagcatcgagagaatccagagcatctcagccgccgtattc cacctcgagcaggtagagcagcccttgcgctctaagaagtgtgtttggcagaagttgttg tctaagcagcgcaagcgagccgttgtggcgtgtttcagaatggcgccgctctacaacctg cccaggcatcgctctattaacctgttcctcacgggctaccagcggctctggatcgaggca gagatgtactcgtttgaggagaagctagtgcaggatctggctaagacgcagccgaagact gatgaagaggaggaggagatcacagacactcagccggaccctcttcatcaactcatcctg cacttcagtcacaacgcactgacagaacgcagctctctagaggaggatcagctgtacatc gcatacgcagacatgatggcaaagagctgtgctgaaaatgaggaagaggatgaggaagga aaagagaaaacatttgaggagaaagagatggagaagcagaagactctgtaccaacaggcc cgactccatgacagaggagcagcagagatggtcttacagatgatcagcgctagtaaaggt cgtttgggtccgatggtcacgttcacgctgaagctcggcatctccattctcaacggcgga aacatcacagtccagcagaaaatgctggactatctgaaggagaagcgagatgtgggtttc ttcaagagtctgtcaggactgatgcagtcgtgcagtgttttggatctgaacgcgttcgag cgtcagaataaggccgagggtttgggtatggtgactgaggaaggttccatcaacgtgagg gagcgcggctctaaagttcttcagaatgacgagttcaccaaagatctgttcaggttcctg cagctcctgtgtgagggacacaataacgacttccagaactttctcaggacgcagacagga aacacgaccacagtcaatataatcatcagcaccgtggactatctgctcagactgcaggag tcaatcagtgacttttactggtattactctggtaaagacgtgatggacgaggcgggccag cggaatttctccaaagctctcgctgtagccaaacagatcttcaactcgctcactgagtac atacagggtccgtgtatcgggaaccagcagagtttggctcacagcagactttgggacgcc gtcgtcggatttctgcacgtcttcgccaacatgcagatgaagctgtcacaggactccagt cagatcgagctgctgaaggagctgatggatctgcagaaggacatgatagtcatgatgctg tcactgctggaaggaaacgtggtgaacgggaccatcggcaagcagatggtggacactctg gtggagtcctccagcaacgtggagatgattctcaaattcttcgacatgttcctcaagctg aaagatctgacgacctcagagaacttcaaggagcacgaccccgaccgtaaaggcgtgatc tccaagaaggagttccagaagtccatggagaaccagaagcagtactctcagtccgagatc gagttcctgctgtcctgcgccgaggccgacgagaatgacatgttcaactacgaagagttc gtcaagcgcttccacgaacccgccaaggacatcggcttcaatgtggcggttctgctcacc aatctgtcggagcacatgcctcacgattcccgactgtccaccttcctgaacctggctgag agcgttgtgaactacttcgagccctacctgggccgcatcgagatcatgggcggcggcaag agaattgagagggtttacttcgagatcagcgagtccagccgaacgcagtgggagaaaccg caggtcaaagagtccaagcggcagtttatcttcgatgtcgtcaacaagggtggagaatcc gagaagatggagctgttcgtgaacttctgcgaggacaccatcttcgagatgcagctggca tctctgatctccgagccggatgctgctgagagacaagaggaggatgatgatgaagatgat actcggagcgtggatctagacgaggacgatgaagatagcgcacaggagtcttcctcagcg ttcgctctggcctgcgtctccatgaggaagagtctctccaacctgcggcagctgctgacc ttcaggagcatgaggagacagtaccgcaagctgaggaagatgagcgtccgggagatgatc cgaggattcttcttcttcttttggatgatcttcactggcatgttccgcttcctctacggc ctcgtctggggcttcttccacatcctatggtccacgctgttcggcggcggtctcgtggaa ggagccaagaacatgaaggtgacggacattctggggaacatgccggatcccacacagttc gggatccacggagacgttctggagctggagaagctggagtactgcgacgtgtcgtcggtg gcggagctcgggcgcatggcggcgggagatcaggcggagatggacctgatgacggagctg atgtacatgcagcccaggagggaaggaggcaagcatggcatggagccggggctgggagac atgtccgaggtgatcggagtggacgctccgtctttagccagcgccgtccatcagaagaaa gctcaggaagccgccagtaagcagtccgctgaatccgagaccaaatcagagtctgagaag gccgatgtggaggacggagagaagaaagaccagcacaagggcaaagaggagagcgtgtca gacgagaagaagccgctgaagaagagacgcggtcagaggaagcagcaggccgaggccttc atggcagcatttttagccggtctggacatccatcagaccaaaaccctgaattatctggcc agaaacttctacaacctgcgattcctggctctgtttgtggcgttcgccatcaacttcatc ctgctcttctacaaggtgaccggtgaggattcagatgatctggacccgtggacgcggcga gaggaagaggaggaggatgaaggtgtactggagtattttgttcttcaggagagcacgggt tacatggctccgaccctgcgcttcctcgccgtcatgcacaccgtcatctccttcctctgt gtgctgggatattactatctgaaggtgccgctggtggtgttcaagcgtgagaaggagatc gcacgcaagctggagttcgacgggctctacatcaccgagcagccgtctgatgatgatatt aaaggccagtgggacagactagtcatcaacacgccgtcttttccaaacaactactgggac aaatttgtcaaacggaaggttattaataagtacggcgatctttacggagccgagcggatc gcggagctgctgggtttggataaaagtgctttagacttcaatcccactgaagagacggtc attaaagacgcctcgctgctgtcctggttgagctccattgacaccaagtatcacgtgtgg aagatgggcgtcgtgttcactgataactcgttcctgtatctggtctggtacaccaccatg tccatcctgggacattataataatttcttcttcgccgctcacctgctggacatcgccatg ggcttcaaaacgctgaggaccatcctgtcctccgtcacacacaacggcaaacagctggtg ctgacagtcgggctgctcgctgtggtcgtgtatctctacaccgtcgtagcgttcaacttc ttccgcaagttctacaacaagagcgcagatgaggatgagcccgatatgaagtgtgatgac atgatgacgtgttatctgttccacatgtacgtgggtgtccgagctggcggcgggatcggt gacgagatcgaggaccccgcgggcgacccgtacgagctctaccggatcctgttcgacatt accttcttcttcttcgtcattgtgatcctgctggccatcatacaaggtctgatcatcgat gcgtttggagagctgagagaccagcaggagcaggtcaaagaggacatggagaccaaatgc ttcatctgtggaatcgggaacgactatttcgacacaacgccacacggctttgagactcac acgttacaagagcacaacctcgccaactacctatttttcttgatgtacctgatcaacaag gatgaaaccgagcacactggtcagcgtttggacagcatgatgccaaaagcacgcgtgttt gtgcgtgtgttcacactccctcggatcccctgcctgcttgcccgtagagaactcaaacct tcgtcaagtgccttacctccatcacatctgagctatgcaacacctgcgtttcctcccgat gtcgtggaggtcgactgtaacgtcgaacacggatcctcacagcagagattcacaaacttc tgtcagctgaaaccctttgagattttgagtttcaataacttagcatcacattcacatgtt tacggttctctgataaaatggagacaatctgggtgttcttcagttcagactgaaaggagc caacaaaaagaacaaagactacagaaaggcctgaacgacacaatggagaaactcaacgcc attcctgatgcatcagcagcagtgatcagaggagaagctgctgaaggtctcactggtgtt ttattgtgctga

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