Staphylococcus aureus subsp. aureus MRSA252 (MRSA): SAR0353
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Entry
SAR0353 CDS
T00182
Symbol
metE
Name
(GenBank) 5-methyltetrahydropteroyltriglutamate--homocyst eine methyltransferase
KO
K00549
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:
2.1.1.14
]
Organism
sar
Staphylococcus aureus subsp. aureus MRSA252 (MRSA)
Pathway
sar00270
Cysteine and methionine metabolism
sar00450
Selenocompound metabolism
sar01100
Metabolic pathways
sar01110
Biosynthesis of secondary metabolites
sar01230
Biosynthesis of amino acids
Module
sar_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
sar00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
SAR0353 (metE)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
SAR0353 (metE)
Enzymes [BR:
sar01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.14 5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
SAR0353 (metE)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Meth_synt_2
Meth_synt_1
Motif
Other DBs
NCBI-ProteinID:
CAG39376
UniProt:
Q6GJW2
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All DBs
Position
complement(397296..399524)
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AA seq
742 aa
AA seq
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MTTIKTSNLGFPRLGRKREWKKAIESYWAKKISKEELDQTLTDLHKENLLLQKYYHLDSI
PVGDFSLYDHILDTSLLFNIIPERFQGRTIDDDLLFDIARGNKDHVASALIKWFNTNYHY
IVPEWDNVEPKVSRNVLLDRFKYAQSLNVNAHPVIVGPITFVKLSKGGHQTFEEKVKTLL
PLYKEVFESLIDAGAEYIQVDEPILVTDDSESYENITREAYDYFEKAGVAKKLVIQTYFE
RAHLKFLSSLPVGGLGLDFVHDNGYNLKQIEAGDFDKSKTLYAGIIDGRNVWASDIEAKK
VLIDKLLAHTNELVIQPSSSLLHVPVSLDDETLDTSVGEGLSFATEKLDELDALRRLFNQ
NDSVKYDKLKARYERFQNQSFKNLDYDFESVRTSRQSPFAQRIEQQQKRLNLPDLPTTTI
GSFPQSREVRKYRADWKNKRITDEAYETFLKNEIARWIKIQEDIGLDVLVHGEFERNDMV
EFFGEKLQGFLVTKFGWVQSYGSRAVKPPIIYGDVKWTAPLTVDETVYAQSLTDKPVKGM
LTGPVTILNWSFERVDLPRKVVQDQIALAINEEVLALEAAGIKVIQVDEPALREGLPLRS
EYHEQYLKDAVLSFKLATSSVRDETQIHTHMCYSQFGQIIHAIHDLDADVISIETSRSHG
DLIKDFEDINYDLGIGLGVYDIHSPRIPTKEEITTAINRSLQQIDRSLFWVNPDCGLKTR
KEEEVKDALTVLVNAVKAKRQE
NT seq
2229 nt
NT seq
+upstream
nt +downstream
nt
atgacaacaattaaaacatcaaacttaggattcccaagattaggtagaaaaagagaatgg
aaaaaagccatcgaaagttattgggcaaagaagatttctaaagaagaattagatcaaaca
ttaactgatctacataaagaaaatttattattacaaaagtactatcacttagatagcatc
ccagttggtgatttctctttatatgaccacattttagatacgtcattattattcaacatc
atcccagaacgtttccaaggaagaactatcgatgatgacttattatttgatatagctcgc
ggtaataaagaccatgttgcaagtgcacttataaaatggtttaacactaactatcattac
atcgtacctgaatgggacaatgttgagcctaaagtgagtcgcaatgtattattagatcgc
tttaaatacgcgcaatctttaaatgttaatgctcaccctgttattgttggtccgattact
tttgttaaattatcaaaaggcggtcaccaaacttttgaagaaaaagttaaaacgttatta
ccactttataaagaagtgtttgaatcattaattgatgcaggtgctgagtacattcaagtt
gatgagccaatcttagttacagacgacagtgaaagctatgaaaatattacacgtgaagct
tatgactatttcgaaaaagctggtgttgctaaaaaattagtcattcaaacatacttcgaa
cgtgcacatcttaaattcttaagttctttacctgttggtggtttaggattagactttgtc
catgataatggctataaccttaaacaaattgaagctggagattttgataaatcaaaaaca
ttatatgctggaattattgatggtcgtaatgtatgggcaagtgacattgaagctaaaaaa
gtcttaatcgataaattgttagcacacactaatgaacttgtcattcaaccatcatcttca
ttattacatgttccagtatctttagatgatgaaacattagatacaagtgttggcgaaggc
ttaagctttgcaactgaaaaattagacgaattagatgcattgcgtcgcctatttaatcaa
aacgatagtgttaaatatgataaattaaaagcacgttatgagcgtttccaaaatcaatca
ttcaaaaacttagattatgatttcgaaagcgtgcgtacttcaagacaatcaccattcgcg
caacgtattgaacaacaacaaaaacgtttgaacttaccggatttaccaacaacaactatt
ggatcattcccacaaagccgagaagttcgaaaataccgtgcagattggaaaaacaaacgc
attacagacgaagcatatgaaacattcttaaaaaatgaaattgctcgatggattaaaatt
caagaagacatcggcttagatgtattagttcacggtgaatttgaacgtaatgacatggtt
gaattcttcggagaaaaattacaaggtttcctagtaactaaattcggttgggtgcaatca
tatggttcacgtgccgtaaaaccaccaatcatttatggtgatgtaaaatggacagcgcct
ttaactgttgatgaaacagtttatgcacaaagcttaacagataaaccagttaaaggtatg
ttaactggacctgtaacaattctaaactggtcatttgaacgtgttgatttaccacgtaaa
gttgttcaagatcaaattgctttagcaatcaacgaagaagtattagcacttgaagctgca
ggaatcaaagttatccaagttgacgaacctgcattacgtgaaggcttaccattacgctct
gaatatcacgaacaatatcttaaagatgctgttttatcatttaaacttgcaacgtcttca
gttcgtgatgaaactcaaatccatacacatatgtgttattctcaattcggtcaaatcatt
catgctattcatgacttagatgctgatgttatttcaattgaaacatctcgtagccatggt
gatttaattaaagactttgaagatattaattatgatttaggtattggtctaggtgtatat
gatattcatagtccacgtattccaacaaaagaagaaattactacagcaatcaatcgttca
ctacaacaaatcgaccgctcattattctgggtaaaccctgactgtggtttgaaaacgcga
aaagaagaagaagttaaagatgcattgactgtgcttgtgaatgctgttaaagctaaacgc
caagaataa
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