Sorex araneus (European shrew): 101539340 Help Entry 101539340         CDS       T07854                                  Symbol CASP3 Name (RefSeq) caspase-3   KO K02187   caspase 3 [EC:3.4.22.56] Organism sara  Sorex araneus (European shrew) Pathway sara01524   Platinum drug resistance sara04010   MAPK signaling pathway sara04115   p53 signaling pathway sara04148   Efferocytosis sara04210   Apoptosis sara04215   Apoptosis - multiple species sara04623   Cytosolic DNA-sensing pathway sara04650   Natural killer cell mediated cytotoxicity sara04657   IL-17 signaling pathway sara04668   TNF signaling pathway sara04726   Serotonergic synapse sara04932   Non-alcoholic fatty liver disease sara04933   AGE-RAGE signaling pathway in diabetic complications sara04936   Alcoholic liver disease sara05010   Alzheimer disease sara05012   Parkinson disease sara05014   Amyotrophic lateral sclerosis sara05016   Huntington disease sara05020   Prion disease sara05022   Pathways of neurodegeneration - multiple diseases sara05132   Salmonella infection sara05133   Pertussis sara05134   Legionellosis sara05145   Toxoplasmosis sara05146   Amoebiasis sara05152   Tuberculosis sara05160   Hepatitis C sara05161   Hepatitis B sara05162   Measles sara05163   Human cytomegalovirus infection sara05164   Influenza A sara05165   Human papillomavirus infection sara05167   Kaposi sarcoma-associated herpesvirus infection sara05168   Herpes simplex virus 1 infection sara05169   Epstein-Barr virus infection sara05170   Human immunodeficiency virus 1 infection sara05200   Pathways in cancer sara05203   Viral carcinogenesis sara05205   Proteoglycans in cancer sara05206   MicroRNAs in cancer sara05210   Colorectal cancer sara05222   Small cell lung cancer sara05416   Viral myocarditis sara05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:sara00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     101539340 (CASP3)    04668 TNF signaling pathway     101539340 (CASP3)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     101539340 (CASP3)   09143 Cell growth and death    04210 Apoptosis     101539340 (CASP3)    04215 Apoptosis - multiple species     101539340 (CASP3)    04115 p53 signaling pathway     101539340 (CASP3)  09150 Organismal Systems   09151 Immune system    04623 Cytosolic DNA-sensing pathway     101539340 (CASP3)    04650 Natural killer cell mediated cytotoxicity     101539340 (CASP3)    04657 IL-17 signaling pathway     101539340 (CASP3)   09156 Nervous system    04726 Serotonergic synapse     101539340 (CASP3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101539340 (CASP3)    05206 MicroRNAs in cancer     101539340 (CASP3)    05205 Proteoglycans in cancer     101539340 (CASP3)    05203 Viral carcinogenesis     101539340 (CASP3)   09162 Cancer: specific types    05210 Colorectal cancer     101539340 (CASP3)    05222 Small cell lung cancer     101539340 (CASP3)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     101539340 (CASP3)    05161 Hepatitis B     101539340 (CASP3)    05160 Hepatitis C     101539340 (CASP3)    05164 Influenza A     101539340 (CASP3)    05162 Measles     101539340 (CASP3)    05168 Herpes simplex virus 1 infection     101539340 (CASP3)    05163 Human cytomegalovirus infection     101539340 (CASP3)    05167 Kaposi sarcoma-associated herpesvirus infection     101539340 (CASP3)    05169 Epstein-Barr virus infection     101539340 (CASP3)    05165 Human papillomavirus infection     101539340 (CASP3)   09171 Infectious disease: bacterial    05132 Salmonella infection     101539340 (CASP3)    05133 Pertussis     101539340 (CASP3)    05134 Legionellosis     101539340 (CASP3)    05152 Tuberculosis     101539340 (CASP3)   09174 Infectious disease: parasitic    05146 Amoebiasis     101539340 (CASP3)    05145 Toxoplasmosis     101539340 (CASP3)   09164 Neurodegenerative disease    05010 Alzheimer disease     101539340 (CASP3)    05012 Parkinson disease     101539340 (CASP3)    05014 Amyotrophic lateral sclerosis     101539340 (CASP3)    05016 Huntington disease     101539340 (CASP3)    05020 Prion disease     101539340 (CASP3)    05022 Pathways of neurodegeneration - multiple diseases     101539340 (CASP3)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     101539340 (CASP3)    05416 Viral myocarditis     101539340 (CASP3)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     101539340 (CASP3)    04932 Non-alcoholic fatty liver disease     101539340 (CASP3)    04933 AGE-RAGE signaling pathway in diabetic complications     101539340 (CASP3)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     101539340 (CASP3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:sara01002]     101539340 (CASP3) Enzymes [BR:sara01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.56  caspase-3      101539340 (CASP3) Peptidases and inhibitors [BR:sara01002]  Cysteine peptidases   Family C14: caspase family    101539340 (CASP3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 Erf4 Motif Other DBs NCBI-GeneID:  101539340 NCBI-ProteinID:  XP_004610417 LinkDB All DBs Position Unknown AA seq 276 aa AA seqDB search MENSEISVDAKSVKNSEVKVIHGSKSVDSGIALDNSYKMDYPEMGVCLIINNKNFKGQGM STRTGTDVDAARLKETFTNLKYEVRIKNDLTCEEIMKLLHSASLEDHSKRSSFICVFLSH GEEGTIFGTDKPIELKILAGFFRGDCCRTLTGKPKIFIIQACRGTELDCGIETDSGSESD MTCQKIPVEADFLYAYSTAPGYYSWRNSKEGSWFIQSLCDILKQYADKLEFMHILTRVNQ KVATEFESYSLDITFHAKKQIPCIMSMLTKELYFYH NT seq 831 nt NT seq  +upstreamnt  +downstreamnt atggagaactctgaaatctcagtggatgcgaaatccgtaaagaattcagaagtgaaggtc attcatggcagcaagtcggtggactctggaatagccttggacaacagttacaaaatggac tatcctgaaatgggcgtgtgtttaataattaataataagaactttaaaggccaaggaatg tcgactcggactggtacagatgtagatgcagcaagactcaaggaaacatttactaacttg aaatacgaagtcaggatcaaaaatgatcttacctgtgaggaaattatgaaattgctgcac agcgcttctttagaagatcatagcaaaaggagcagttttatttgtgtgtttttaagccat ggtgaagaaggaactatttttggaacagataaacctattgagctgaagatcttagcaggt tttttcagaggagattgttgcagaactctaactggaaaaccgaaaattttcattattcag gcctgccgaggtacagaactcgactgtggaatagagactgacagtggttctgagagtgac atgacgtgtcagaagattccggtggaagctgacttcttgtatgcgtattctacagcacct ggttactattcttggcgaaattcaaaggaaggatcctggttcattcagtcactttgtgat atattgaagcagtacgctgacaaacttgagttcatgcacattcttactcgggtcaaccaa aaggtagcaacagaatttgagtcctattctctggatataactttccacgcgaagaagcag attccatgtattatgtctatgctcacaaaagaactgtatttttatcactga

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