Salmo salar (Atlantic salmon): 106608253 Help Entry 106608253         CDS       T04363                                  Name (RefSeq) ryanodine receptor 3-like   KO K04963   ryanodine receptor 3 Organism sasa  Salmo salar (Atlantic salmon) Pathway sasa04020   Calcium signaling pathway sasa04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:sasa00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     106608253    04020 Calcium signaling pathway     106608253  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:sasa04040]     106608253 Ion channels [BR:sasa04040]  Voltage-gated cation channels   Ryanodine receptor    106608253 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 Ins145_P3_rec SPRY MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_8 EF-hand_6 Motif Other DBs NCBI-GeneID:  106608253 NCBI-ProteinID:  XP_014061572 LinkDB All DBs Position ssa06:80093085..80333150 Genome browser AA seq 4850 aa AA seqDB search MAEGGEGEDDIQFLRTDDEVVLQSVATIQKENRKFCLSVEGLGNRLCFLEPTSEAKYVPP DLCICCFILEQSLSVRALQEMLAHTVPNNEGKADHEQWAAQGGGHRTLLYGHAILLRHSF SGMYLTCLKTSRSLTDKLSFDVGLQEDSIGEACWWTIHPASKQRSEGEKVRIGDDLILVS VSTERYLHLSISSGSFQVDASFMQTLWNVQPTCSGSNVAVGFLCGGHVMHLCHGHDESLT IPGSEASEMEQRIVNYEMGKGASRARSLWRLEPLRIGWSGSHIRYGQAFRLRHLSTGQYL ALTEEHGLVLQEREKSDTKSTSFCFRATKEKIESGTKNRDIEGMGVAEIKYGDSACFVMH VATGLWLSYQAPDAKASRIGPLKRRACLHAEGHMDDGLTLQRCQHEEARAVRIIRNTTVL FSHFIKGLDSIGRDKNVEVSLPNFDEVLQTLDDLIEYFKQPDSELEHEEKQTLLRSLIKR QDLFKEEGMLALLVMCIDRLNLYNSAAHFGEHAGEEAGAAWKNILNLLYQLLASLIKGNR NNCTQFSRNLDWLVSKLERLESSSGILEVLHCILIESPEALNIIQKGHIKSIISLLYKHG RNHKILDVLCSLCVCNGVAVRANQNLICDHLLPKRDLLLQTRLVNDVQSMRPNIFLGVAE GSAQYKKWYFELMIDQVNHYVTSEPSHLRVGWASTKGYAPYPGGGEGWGGNGVGDDLYSY SFDGLYLWSGRISRAVASINQHLLNSDDVVSCCLDLGAPSMSFRINGQPVQGMFEDFNTD GFFFPVVSFSAGVKVRFLLGGRHGDFKFLPPAGYSPCYEALLPKEKMRVEAVKEYKRDYG GVRDLLGTTQFLSQASFIPTPVDTSQIVLPPHLDNVRDRLAENIHELWGMNKIELGWCYG KVRDDNKRQHPCLVDFTKLPETERNYNLQMSSETLKTLLALGCHVTQTNVNAEEDLKKVK LPKDYVMSNGYKPTPLDLSEVKLTAGHEVLVDKLAENAHNVWAKERIKQGWTYGIQQDVK SRRNPRLVPYALLDERTKKSNRDSLREAIRTLVGYGYNIDPPDQEPCHIVEKQSIETIRF FRVEQTYAVKTGKWYFEFEALTGGDMRVGWARPGCRSDFDLGMDDQAYVFDGYKGRRMHM GARFFGQSWNEGDVVGCMINMEDKSMVFTLNGELLITNKGSELCFVDFETDDGFIPVCCL AQSEIGRMNLGKDASSFKYYTTCGLQEGFEPFAVNMNREVTMWFSKRLPTFVNIPKDHNH IEVTRIDGTVDNPPCLKVTHKTFGTQQSNSDMLYCRLSMPVELHAPHVSPDESQKLSQPP KEDDYGRITTYYHSVRVFAGQDPASVWVGWVTPDYHYHSKQFSLNKTRTVTVTLGDERGR VHESVRRSNCYMVCAGDVVGSSHSSSRSNIDLEIGCLVDLATGFLSFTANGKELATTYEV ESNTKLFPAVFVRPTSTNLFQFEFVKIKAAMPLSSAIFKSEQRNPVPQCPPRLDVQTIVA VLWSRMPNTFLTVETARVSERHGWVVQCLEPLQMMAVHIPEENRCLDILELSENEGLRKF HYHTLMLYCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLSGMLREGFYNVLMSIHLET AKEARLMMNNEFIIPVTDETRSIKLFPDESKRHSLPGVGLSTSLKPRLIFSPLSFITTKK QQHLHSPQIPLGILKEKAISMLTEAVQGGGSHIRDPVGGSVEYQFVPILKLIGTLLIMGV LTSEEVRLILLLIDPNVFGEPEEEEVEAASAGGGEKEEVSSNEEKAVEAGEEETKDVKPT VKGLLEKTLPESVKRQMCELLHYFCDCELKQRIEAIVSFSDSFVSKLQYNQKFRYNELML ALNMSAAVTAKKTKEFRSPPQEQINILLNFAAGEDCPCPEEIQEDLYKFHDELRLHCGIP VEEEEEEEDTSIKGRLLAMLYKIKGPPKKLEEEPTEEEQAAPTNLKELISQTMASWAQEC SIQDPELVRVMFSLLRRQYDGIGALLRAMKKSYTISAVSVQDCVNLLASLGQIRSLLSVR MGKEEEKLMIDGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGGDKSQEIAFPKMV ASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASPAMRGSTPLDVAASSVMDNNSL ALALEEPDLEKVVTYLAGCGLQSCAMLLAKGYPDIGWNPIEGERYLSFLRFAVFSNGESV EENSNTVVKLLIRRPECFGPALRGEGGNGLLAAMLEAIKISEDPALDLPSTADGEPSGSD EEEEVAHTGNAIMSFYSALIDLLGRCAPEMHLINKGKGEALRIRAILRSLVPTTDLVGII SIPLKMPIVNKDGSVTEPDMSASFCPDHKAPMVLFLDRVYGVEDQSFLLHLLEVGFLPDL RASASLDTDVLSTTETALAMNRYIGSALLPLLTRCADQFSGTEHYAALIDSTLHTIYRLS KGRSLTKAQRDSIEECLLAICKHLRPSMMQQLLRRLVFDVPLLAEYCKMPLRLLTEHYEQ SWMYYCLPSGLGSSGMASEEELLLTKKLFWGIFDSLSTKKFDSDLFKTAMACLSAIAGAL PPDYMDASPGVTLEKQASVDAHGNFDPKPINTANMSLPEKLDYIANKFAEHSHVKWSSEK VTAGWKMGECVDDDAKTHPLLKPYKSLSEKERETYRWPVKESLKSMLAMGWNMERTKEGE AMLIRKQSKISESTQDNDNEFIPEPPLDLNNITLSRELQGMVEVVAENYHNIWAKKKKAE LNSKGGGSHPLLVPYDTLTAKEKYRDREKVQDLFKFLQINGYTITRGLKDMEQDSSSMEK RFAYTFLKRLLKYVDSAQEFIAHLEAMATSGKTDKSPHDQEIKFFAKVLLPLIDMYFKNH SMYFLSSPSKNLSSSGYASNKEKEMITSLFCKMAALVRHRISLFGSDSAIMVSCLHILAH SLDTRTVMKSGSEMVKAGVRTLFENAAEDLEKTLEMLKLGKFSQSRSQMKGLSQNITYAT TALLPILTALFEHVTMHNFGVCLLVDDVQLSCYRIVTCLYSLGTGKHIFMERHLPALGEC LATLVGAMPVAFLEPDLNAHNPLSVFNTKTQRERAILSMPDSVEEMCSDMPRLDRLLKDI NDISESGARYTEMPQVIEVILPMLCNYLSYWWERGTENSAPHTACCTTVCSHHLSIILGN ILKILNNNLGIDDAPWMKRIAVYSQPIICKAAADLLKSHFLPTLEKLRKKTVKVVAEEEL LKADIKGDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRSRWLKRPDAQSNELFTMV AEIFILWCKSHNFKREEQNFVVQNEINNLSFLTGEHKTKMSKSGGDQDRKHKKRRGELYS VQTSLIVAALKKMLPIGLNMCTPGDQELISLAKIRYSLKDTDDEVKDHLRENLHLQDKSD DLAVQWQMNLYKDVVVVGSEEHADPEQTVDRIQSISAAVFHLEQVEQPLRMKKCVFQKLL SKQRKRAVVACFRMAPLYNLPRHRSINLFVLGYVRLWIETEEYSFEERLVQDLAKTPMKI VEEEEEEEVEIQPDPLHQLILHFSHNALTERSFLEEDPLYIAYADMMAKSCAEDEEEEEE EEGKEKTFEEKEMEKQKILYQQARLHARGAAEMVLQMISASKGRLGPMVTCTLKLGISIL NGGNVLVQQKMLDYLKEKRDAGFFKSLSGLMQSCSVLDLNAFERQNKAEGLGMVTDEGSI NSERGSKVLTNDDFTKDLFRFLQLLCEGHNGDFQNFLRTQTGNTLTVNIIISTVDYLLRL QESISDFYWYYSGKDIIDEAGQVNFSKALAVAKQIFNSLTEYIQGPCIGNQQSLAHSRLW DAVVGFLHVFANMQMKLSQDSCQIELLKELMDLQQDMVVMMLSLLEGNVVNGTIGKQMVD TLVESSSNVEMILKFFDMFLKIKDLTTSDNFREYDPDNKGVISKKDFQKSMENQKQYTQS EIEFLLSCAEADENDMFNYEEFVERFHEPAKDIGFNIAVLLTNLSEHMPHDPRLATFLEP AESVLNYFEPYLGRIEIMGGGKRIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGG ESEKMEMFVNFCEDTIFEMQLASQISEPEVVERPEEEEEEVHNLLEELAEQEEERELEAS SAFTMVCVSAKKKISNFREMLTFKSLKKQYKKSKKLSMKEVILGFFSFFWTLFAGFFKGI YSLIFGFFHLIWSSMFGGGLVEGAKNMKVTDILGNMPDPTQFGIHGDVLETEKVEVSDSV SGGTDQAIKPSDKAEQDILMEMINPMPKKGEGLKHVDPGLGDVSENLTAETTATVEKKNA ASEPTESEPEKADTEKKEKEDKVKVEQPKEEMAQDKPVLKSRNGQSKEAPTSFFASFLAG LEVYQAKMLNTLARNFYNMRFLALFVAFAINFILLFYRVTAAEDDEDDSWTSSDDEDEGG EEYFVLEESTGYMAPILCFLAVFHTALSILCLVGYYFLKVPLVVFKREKGIARLLEFEGL YITEQPADDDIMGQWDRLVINTPSFPNNYWDKFIKRKVINKYGDLYGAERIAELLGLDKS ALDFDPTQETVVEAASLVSWLSSIDTKYHIWKMGVVLTDNSFLYLIWYATMSILGHYNNF FFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSE DEDAPDMKCDDMMTCYLFHLYAGVRAGGGIGDELEDPAGDPYELWRILFDITFFFFVIVI LLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTTPHGFETHTLQEHNLAN YLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDLLG NT seq 14553 nt NT seq  +upstreamnt  +downstreamnt atggctgagggcggagaaggagaagatgatatacagttcttgcgaactgatgatgaggtg gtgctgcagagtgttgccaccatccagaaggagaatcgcaagttttgtctgtccgtggag ggactcggaaatcgactatgcttcctagaacctacatctgaggctaagtatgttcctcct gacctttgtatctgttgtttcatcttggagcagtccctgtctgtccgggccctgcaggag atgttggctcatacagtgcctaacaacgaggggaaagcggaccatgagcagtgggcggcc caggggggtggacaccggaccctgctctatggtcacgccatcctcctacgccactccttc agcggaatgtacctgacctgcttgaagacatcaagatcgttgacagacaaactgtcattt gacgtgggattacaagaagattcaataggagaggcatgttggtggaccatccaccctgcg tccaagcagaggtcagagggagagaaggtccgtatcggagacgacctcatcctggtcagc gtgtccacagagaggtacctgcacctgtccatctccagtggtagtttccaggtggatgcc tcctttatgcagactctgtggaacgtccagcctacctgctcaggaagcaacgtggctgta ggattcctgtgtggtggtcacgtgatgcatctttgtcacgggcatgatgagagtctgacc atacctggatcagaggccagcgagatggagcagaggattgtgaactatgagatgggtaaa ggagcatccagggcccgctctctctggaggctggagcccctcaggatcggttggagcggt agccacattcgctatgggcaggcgttccgtctgcgtcacctgtccaccggtcaatacctg gcgctgaccgaagaacatggtctggtcttacaggagagagagaagtctgataccaagtcc acctctttctgcttcagggctaccaaggaaaagatagagtcaggtacaaagaatcgagac atagaaggtatgggagtagcagagatcaagtatggggactccgcctgcttcgtgatgcac gtggctacaggtctgtggctgtcctaccaggcgcctgacgctaaagcctcccgcatagga cccctgaagagaagggcctgtctgcatgctgagggtcatatggacgacggtctgaccctt cagcgttgtcaacacgaggaggcacgggctgtacgcatcatcaggaacactactgtcctc ttcagccacttcatcaagggtcttgacagtataggaagggataagaacgtggaggtgtct ctgcctaactttgacgaggtgttgcagacgctggatgatctgattgagtatttcaaacag cctgactcagaactggaacatgaggagaaacaaactctgctgagatctctcatcaaacga caggacctcttcaaagaggagggcatgctggccctgctggtgatgtgcattgaccgtctc aacctgtacaacagcgctgctcactttggagagcatgctggggaagaggctggggcggct tggaagaacatcctcaacctactctaccaactactggcctctctgatcaaagggaaccgg aacaactgtacccagttctccaggaacctggactggctggtcagcaagctggagagactg gagtcctcatcgggtatcctggaggtgctccattgtatcctgatagagtctccagaggct ctgaacatcatccagaaaggacacatcaagtccatcatctccctgctctacaaacacgga cgcaaccacaagatcctggacgttctgtgctctctgtgtgtgtgtaacggggtggcagtg agagccaatcagaacctcatctgtgatcacctgcttccgaagagagacctgctcctccag acacgattggtcaatgacgttcagagtatgaggcctaacatcttcctaggagtggcagag ggttcagcccagtataagaagtggtactttgagttgatgatcgaccaggtgaaccactat gtgaccagcgagccgtcccacctgcgtgtgggctgggcctccactaagggttatgccccc tacccggggggtggagagggatgggggggcaatggagtgggtgacgacctttactcatac agctttgacggactctacctgtggtcaggccgtatctcccgggcggtagcttcgatcaac cagcacttgttgaacagtgatgacgtggtgagctgttgtctggacctgggcgctccctcc atgtccttcaggatcaatggccagccagtacagggcatgtttgaagacttcaacaccgat ggattcttcttcccagtagtcagcttctctgcgggggtcaaggtgcgtttcctgctgggt ggtcgccatggagactttaagttcctgcccccggcgggttactccccgtgttacgaggcc cttctccccaaggagaagatgagggtggaggctgtaaaggagtacaagagagactatgga ggggtcagggacctactggggacaacacagttcctctcccaggcctcattcatccccaca cctgtagacaccagccagattgttctacctcctcacctggacaacgtgcgtgacagacta gcagagaacatccatgaactttggggcatgaacaagattgaactgggatggtgctatggc aaggttcgagatgacaacaagaggcagcacccttgcctggtggatttcaccaagctgcct gaaactgagaggaactataacctgcagatgtctagtgaaactctcaagaccctgttggca ttgggatgtcatgtgacacagaccaacgttaacgctgaggaagatctgaagaaagtcaaa ctgcccaaagactatgtgatgtctaatgggtacaagccaacgccgctggatctttcggag gtgaaactgacagctggtcatgaggttctggtagataaactggcggagaatgctcacaac gtttgggccaaggagaggatcaaacaaggatggacctacggcatacagcaggatgtgaag agcaggcgaaaccctcgtctggtgccgtatgctttactagacgagagaaccaagaagtct aacagagacagtctgagagaggccatcaggaccctggtgggatatggctacaacatcgac cccccagaccaggaaccctgtcatattgtggagaagcagagcattgagacgatcaggttc ttccgcgtagagcagacgtatgcagtgaagacagggaagtggtactttgagtttgaggcc ctgaccggaggggacatgagggttggctgggctagaccaggctgtaggtcagactttgac ctgggcatggacgaccaggcctacgtcttcgatggatacaagggtcgtcgaatgcacatg ggggcgcgtttcttcggccagtcatggaacgagggagacgtggtgggctgcatgatcaac atggaggacaagtctatggtcttcaccctcaatggagagctactcatcactaacaaggga tccgagctctgcttcgttgacttcgagacagatgatggcttcatcccagtgtgttgtctg gcccagtctgagattggccgtatgaacctggggaaggacgccagcagctttaagtactac accacgtgtggcctgcaggagggcttcgaacccttcgctgtcaacatgaacagagaggtc accatgtggttcagcaaacgcctgcctaccttcgtcaacatccccaaggaccacaaccac atcgaggtgacgaggatagatgggacagtggacaaccctccgtgcctgaaggtgacccac aagacatttgggacccagcagagcaacagtgacatgctgtactgcagactgagcatgcct gtagagctccacgctcctcatgtcagtcctgacgagtctcagaaactcagtcagcctcca aaggaagatgattatggcagaattacaacgtattatcactcagtgagggtgtttgctggc caggacccagcatcggtgtgggttggctgggtaacccctgactaccattatcatagcaaa caattcagccttaacaagacacgcacggttactgtaaccctgggagacgagagaggacgc gtccacgagagtgttcggaggagtaactgctacatggtgtgtgctggagatgttgtcggc tcctcccactcctcatcccggtctaacatcgacctggagattggctgtctcgttgacctg gcaacaggctttctctccttcacagccaatggcaaggagctggcgaccacctatgaggtg gagtccaacactaagctgttccctgctgtgtttgtgcgtcccaccagcaccaacctcttc cagtttgagtttgtcaagatcaaggccgccatgcccctgtcgtcagccatctttaagagt gagcagcgtaaccctgtgccccagtgtccaccacgtctggacgttcagaccatcgtagcg gtgctgtggagccgtatgccaaacaccttcctcaccgtggagaccgccagggtctcagag agacacggctgggtggtgcagtgtctggagccactgcagatgatggctgttcatatacct gaggaaaacaggtgtctggacatcctggagctatcggagaacgagggtctgaggaagttc cactaccacaccctgatgctctactgtgccctctgcgcattgggcaacacccgcgtggca cacgccctctgctcccacctcgaccaatcacagctgctctacaccatcgacaaccaatac ctgtccggcatgctgagagagggattctataatgttcttatgagcatccacctggagaca gcaaaagaggctcgtctgatgatgaacaatgagtttatcatccctgtgaccgatgagacg cgctccatcaagctgttccctgacgagtccaagagacactctctacccggggtaggcctc agcacctctctgaaaccacgcctcatcttctcccctctctccttcatcaccaccaagaaa cagcagcacctccacagtccccagatccccctgggtatcctgaaggagaaggccatcagt atgctgactgaggcggtgcagggaggaggcagtcacatcagagacccagtaggaggcagt gtggagtaccagtttgtccccatcctcaagctgatcgggaccttgctgatcatgggggta ctcaccagcgaggaggtgaggctgatcctgctcctcattgaccctaatgtgttcggggag ccagaggaggaggaggtggaggcagcatcagcaggaggaggagagaaggaggaggtgagc agcaacgaggagaaggctgtggaggctggtgaggaggagaccaaggacgtcaaaccgacc gtgaagggactgctggagaagacactgcctgagtctgtcaaacgacagatgtgtgagctg ctgcactacttttgtgactgtgagttgaagcagcgtatcgaggccatcgtgtccttctca gacagctttgtgtccaagctgcagtacaaccagaagttcaggtacaacgagttgatgtta gccctcaacatgtctgctgccgtcactgccaagaagaccaaggagttcagatcccctcca caggaacagatcaacatcctgttaaactttgctgctggggaggactgtccctgtcctgaa gagattcaggaggacctctacaaatttcatgatgagctgagactgcactgcggcatccca gtggaggaggaggaggaggaggaagacacgtctataaagggtcgtctgctggccatgctc tataagatcaagggaccgcccaagaaactagaggaggaacctactgaagaggaacaggct gctcctaccaacctgaaggagttgatcagccagaccatggctagctgggctcaggagtgc agcatccaggacccagagctggttcgtgtgatgttcagcctgctgagacgtcagtacgac ggcattggagcgctgctcagggccatgaagaagagttacaccatctctgctgtgtcagta caggactgtgtcaacctcctggcctctctgggccagatcagatcactgctgtctgtacgc atggggaaagaagaggagaaactcatgatcgacggactgggtgacataatgaacaacaag gtgttctaccagcaccccaacctaatgagagtcctggggatgcatgagactgtcatggag gtgatggtcaacgtgctgggaggagacaagtcacaggagatagcgttccccaagatggtc gccagctgctgtcggttcctgtgttacttttgtcgtatcagtcgacagaaccagaaggcc atgtttgaccacctcagctacctactggagaacagctctgtcggactggcctccccagcc atgaggggatctactcccctggacgtagcagcgtcttcagtgatggacaacaacagcctg gccctcgctctggaggagcctgaccttgagaaggtggtaacctacctggcaggctgtggt ctgcagagctgtgccatgctcctggctaaaggataccctgacattggctggaaccccata gagggagagagatacctgtccttcctccgcttcgctgtcttcagcaatggtgagagtgta gaggagaactctaacacagtggtgaagctgctgatcaggcgtccggagtgttttggtccc gctctgagaggagaggggggcaacggcctgctggcggccatgctggaagccattaagata tccgaggaccctgctctggacctgccctctacagccgatggggaaccttctgggtctgat gaggaggaggaggttgcccacacaggaaacgccatcatgtccttttactctgcccttatt gacctgctgggacgctgcgcccctgagatgcacttgatcaacaagggtaaaggcgaggca ttgcgtatccgtgccatcctgcgctccctggttcctaccacagacctagtgggcatcatc agtataccactcaagatgcccatcgtcaataaagacggtagtgtgacagagccagacatg tcagctagtttctgtccggaccacaaggcccccatggtgttgtttctggaccgcgtgtac ggcgtggaggaccagagctttctgctacacctgttggaggtgggcttcctgcctgacctc cgcgcctccgcctccctggacacggatgtgctgagcaccacagagaccgctctggccatg aacaggtacattggttcagccctgcttcccctgctgaccaggtgtgctgaccagttctcg ggcacggagcactacgcagcgctcatcgactctacgctccacactatctatcggctgtcc aagggacgctccctcaccaaggcccagagagactctatcgaggagtgtttgctcgcaatc tgcaaacacctgcgtccctccatgatgcagcagctgctgagacgtctggtgtttgatgtt cccctgctggcagagtactgcaagatgccactcaggctgctaactgaacactatgagcag agctggatgtactactgtcttccctcggggctggggagctccggcatggcctcagaggaa gaactgctgctcaccaaaaaactattctggggaatattcgactcgctctcaacaaagaag tttgactctgacctgttcaagactgccatggcctgtctgagtgccattgctggggcatta ccacctgactatatggatgccagccccggtgtcaccctggagaagcaggcgtctgtggat gcacacggcaacttcgaccccaaacccatcaacactgccaatatgtcccttccagagaaa ctggactacatcgccaacaagtttgcagagcattcccacgtcaaatggtcctcagagaag gtgacagcgggatggaaaatgggagagtgcgtagatgatgatgccaaaactcaccctctg ctgaagccttacaagtcactcagtgagaaggagagggagacgtaccgctggccagtgaag gagtctctaaagagtatgttagctatgggctggaacatggagaggaccaaagagggagag gccatgttaatcaggaaacaaagcaagatctcagagtccactcaggataatgataacgaa ttcatcccggaaccaccattggatctgaacaatattactctatccagagagttgcagggg atggtggaggtagtagcagagaactaccacaacatctgggccaagaagaagaaggctgag ctgaacagtaaaggaggagggagccacccattgctggtgccctatgacactctgacagcc aaggagaaatacagagacagagagaaggtccaggatctctttaaatttcttcagatcaat ggatacactatcaccagaggtctgaaggacatggagcaagactcatcgtccatggagaag aggtttgcttacacgtttctcaagaggttgctgaagtatgtggactcggctcaggagttc atcgcccacctagaggccatggccaccagcggaaagacagacaaatcgcctcacgatcag gaaatcaagttcttcgccaaggtgctgctaccactcatagacatgtactttaagaaccac agcatgtacttcctgtcctcgcccagtaagaacctgagcagcagtggctacgcctctaac aaggagaaggagatgatcaccagcctgttctgtaagatggcagctcttgtcagacacagg atttccctctttgggagcgactcggctattatggtgagctgtctacacatcctggctcat tccctcgacacaaggacggtgatgaagtcaggctcagagatggtgaaggctggggtcagg acattatttgagaatgcagcagaggacctagagaagaccctggagatgctgaagctgggg aagttcagccagtcccggagccagatgaagggcttgtcccagaacatcacctacgccacc accgctctactgcccatcctcacagccctgttcgaacatgtcaccatgcacaactttgga gtctgcctgcttgtggatgatgtccagctgtcgtgctatcgcattgtgacgtgtctctac tcattgggcacggggaaacacatcttcatggagaggcacctaccagccctaggagagtgt ctggccaccctggtaggagccatgcctgtagctttcctggagcctgatctcaatgctcac aaccccctgtctgtcttcaacaccaagacacagcgagagagggccatcttgagtatgcct gactctgtggaggagatgtgttcagacatgcctcgtctggatcgcctgctgaaggacatc aacgacatctcagagtctggagcacgctacacagagatgccacaggtgattgaggtgatc ctgcccatgttgtgtaactacttgtcctattggtgggagagaggaacagagaactctgct ccacacacagcctgctgcaccaccgtgtgctcccaccacctcagcatcatcttggggaac atcctcaagatcctcaacaacaacctgggcatcgatgatgctccctggatgaagaggatc gcagtctactcccagccaatcatctgtaaggctgcagcggacctcctgaagagtcacttc ctgcccactctggagaaactcaggaaaaagacagtcaaggtggtagcagaggaggagctg ctgaaggctgacattaaaggagacactcaggaagctgagcttctcattctggatgagttt gctgtcctctgtagagacctgtacgccttctacccaatgctcatccgctatgtggacaac aacaggtccagatggttgaagaggcctgatgctcagtccaacgagctcttcaccatggtg gcggagatcttcattctgtggtgcaaatcacacaacttcaaaagggaagagcagaacttt gtggttcagaatgaaatcaacaacctgtctttcttgactggggaacataagaccaagatg tccaagtcaggtggtgaccaggataggaagcacaagaagcggcgtggagagttatactct gtccagacctctctgatcgtagccgcactgaagaagatgctgcccatcggactcaacatg tgcaccccaggagaccaggagctcatctcactggccaagataagatacagtctgaaagac acagacgatgaggtgaaggatcacttgcgtgagaacctacatcttcaggacaagtctgat gacctggcagtgcagtggcagatgaacctgtataaggatgtggtggtggtggggagtgag gaacatgcagacccagaacaaactgtggacagaatacaaagcatctctgctgcagtcttc cacctggagcaggtggagcagcctctgaggatgaagaagtgtgtgttccagaagctgctg tccaaacagcgtaaacgtgccgtggtggcctgcttccgcatggctcctctctacaacctc cccaggcatcgttctattaatctcttcgtgttgggctatgtgagactatggatagagaca gaggagtactcctttgaggagaggctagtgcaggacctagcaaaaaccccaatgaagatc gtggaggaggaggaagaggaggaggttgagattcagccagaccctcttcatcagcttatc cttcactttagccacaacgccctcacagagagaagtttcttggaagaagatccgttatat attgcgtatgcagacatgatggcaaagagttgtgcagaggatgaagaggaggaagaagag gaagaggggaaagagaagacatttgaggagaaagagatggagaaacagaagatcttgtac cagcaggccaggctccacgcccgcggggctgctgagatggtgctacagatgatcagtgcc agtaaaggtcgactaggtcctatggtgacctgcaccctcaaactgggcatctccatcctc aacggaggcaacgtgctggtccagcagaaaatgctggattatctgaaagagaaaagagat gcaggctttttcaagagtttgtcaggcctcatgcagtcctgcagtgtcctggacttaaat gcctttgagagacagaacaaagcggaaggtctggggatggtgacagatgaaggatccatc aacagtgagcggggttccaaagtgctgacgaatgatgacttcactaaagatctgttcagg tttttacaactgctctgtgaggggcacaacggggatttccaaaacttcctgagaacacaa acaggaaacacgttgacagtcaacattatcatcagcacagtggactacctgctacgcctt caggaatctatcagtgacttctactggtattattctgggaaagacattatcgatgaggca ggacaggtcaacttctccaaagccttagctgtcgcaaagcagatctttaactcactcact gagtacatccagggcccatgtattgggaaccagcagagtctggcccacagcagactgtgg gatgcagtggtgggattcctgcatgtgtttgccaacatgcagatgaagctgtcccaggac tcgtgtcagattgagctgctgaaggagttgatggatcttcagcaggacatggtggtgatg atgctgtcactgctggagggcaatgtggtgaatggaacgattggaaagcagatggtggac actctggtggagtcctccagcaacgtagagatgatcctcaagttctttgacatgttcctc aagatcaaggacctgaccacctctgacaacttcagggagtatgaccctgataacaagggg gtcatctccaaaaaagatttccagaagtccatggagaaccagaagcagtacacccagtcg gagattgagttcctgctctcctgtgccgaggccgatgagaacgacatgttcaactacgag gagtttgtggagcggttccacgagccagccaaagacattggcttcaacatagccgtgctg ctcactaacctctctgagcacatgcctcacgacccccgtctggccaccttcctggaaccg gccgagagcgtgctgaactactttgagccatacctgggccgcattgagatcatgggtgga gggaagcgcatcgagagggtctactttgagatcagcgagtccagccgcacacagtgggag aagccacaggtcaaagagtccaagagacagttcatctttgacgtggtcaacgagggtgga gagagcgagaagatggagatgtttgtgaacttctgcgaagacacgatctttgagatgcag ctagcatctcagatctcggagccagaagtggtggagcgcccggaggaggaagaggaggag gtgcacaaccttctagaagagctggctgagcaagaagaggagagagagctggaggcttcc tcggctttcaccatggtctgcgtctccgctaagaagaagatctccaacttcagagagatg ctgaccttcaagagcctcaagaagcagtacaagaagtccaagaagctgagcatgaaggag gtgatccttgggttcttctccttcttctggacactctttgcagggttcttcaaggggatc tacagcctcatcttcggattcttccacctcatctggtcatccatgttcggaggaggcctc gtcgaaggagccaagaacatgaaggtgacagacatcttgggcaatatgcccgatcccacc cagttcggtatccacggcgacgtgttggagacagagaaggtggaggtgagtgactcggtg tcgggcggaacagaccaggccatcaaaccatcggacaaggcagagcaggacatcttaatg gagatgattaatccgatgccaaagaaaggggaagggttaaaacatgttgatcctggactg ggagacgtctctgagaatctgaccgctgagaccaccgccactgtggagaagaagaatgct gcttctgaaccaacggagtcggaaccagagaaagcagacacagagaagaaggaaaaggaa gacaaggtcaaggtggagcagcctaaagaggaaatggctcaggataagcccgttctcaag tccagaaacggccaatcaaaggaggctcctacttccttctttgccagcttcttggctggg ctggaggtctaccaggccaagatgctgaacacgctggctcgaaacttctacaacatgcgt ttcctggctctgtttgtggcgtttgccatcaacttcattctactgttctacagggtgact gctgctgaggatgatgaggatgactcctggactagttctgatgatgaagatgaaggtggt gaggagtactttgtcctggaggagagtacaggctacatggcccctattctgtgtttcctg gctgtgttccacactgccctctctatcctctgtttggttggctactactttctcaaggtg cctctggtggtgtttaagagagagaaggggatcgccaggctgttggagtttgaaggtctc tacatcacagagcagccggcagacgatgacatcatgggacagtgggaccgcctcgtcatc aacaccccatccttccccaataactactgggacaagtttatcaaacggaaggtcattaat aagtatggagacctgtatggagctgagcggatagctgagctgttgggtctggataagagc gccctggacttcgaccctactcaggagaccgtggtggaggcggcttctcttgtatcctgg ttgagctctatcgacaccaagtaccacatctggaaaatgggagtggtgctgactgataac tcgttcctgtacctgatctggtacgccaccatgtccatcctggggcactacaacaacttc ttcttcgctgcccatctgctggacatcgccatgggcttcaagaccctccggaccatcctg tcctccgtcactcacaacggaaaacagttggtgctgactgtagggctgttggcggtggtg gtgtatctgtacactgtggtggccttcaacttcttcaggaagttctacaacaagagcgag gatgaggacgcacctgacatgaagtgtgacgacatgatgacttgctatctgttccacctg tacgccggggtgagggccggcggtggtattggtgatgagctcgaggacccggcaggagac ccctacgagctgtggcgtatcctctttgacatcaccttcttcttcttcgtcatcgtcatc ctcctggccatcattcagggtttgattattgatgcgtttggggaactgagagaccagcag gagcaggtgaaggaggatatggagactaaatgcttcatctgtggaattggaaacgattac tttgacacgacaccccacggctttgagacccacaccttacaagagcacaacctggccaac tacctcttcttcctgatgtacctcatcaacaaggacgagactgaacacactggtcaggag tcatatgtgtggaagatgtaccaggagagatgctgggacttcttccctgctggggactgt ttcaggaagcagtatgaggacctgcttgggtag

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