Salmo salar (Atlantic salmon): 106610839 Help Entry 106610839         CDS       T04363                                  Name (RefSeq) ryanodine receptor 3-like   KO K04963   ryanodine receptor 3 Organism sasa  Salmo salar (Atlantic salmon) Pathway sasa04020   Calcium signaling pathway sasa04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:sasa00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     106610839    04020 Calcium signaling pathway     106610839  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:sasa04040]     106610839 Ion channels [BR:sasa04040]  Voltage-gated cation channels   Ryanodine receptor    106610839 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 MIR SPRY Ins145_P3_rec RIH_assoc Ion_trans EF-hand_7 EF-hand_1 Motif Other DBs NCBI-GeneID:  106610839 NCBI-ProteinID:  XP_014065927 LinkDB All DBs Position ssa09:20227392..20389726 Genome browser AA seq 4910 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQCVACIHKENRKFCLTAEGLGNRLCYLEPTSEAKYVPP DLCICNFVLEQSLSVRALQEMLAKTGQNSEGPRGKDRWAAQGGGHRTLLYGHAILLRHSF SAMYLTCLKTSRSQTDKLSFDVGLQQDSTGEACWWTIHPASKQRSEGEKVRIGDDLILVS VSSERYLHLSISNGNIQVDASFMQTLWNVHPTCSGSNVEEGYLLGGHVLRLFHGHDEVLT IPGSDQSDQQQRIVNYETGNAGAKARSLWRLEPLRISWSGSHIRWGQPFRLRHLTTGHYL SLTEERGVVLQDREKSDTSSTAFCFRASKEKLESSPKRDIEGMGMAEIKYGDSICFVMHV ATGLWLSYQAPDVKSSRLGPLKRRACLHSEGHMDDGLTLQRCQHEESRAARIIRNTTRLF SHFIRDLDCLGGKNRASVALPIEEVLQTLNDLITYFQVPNAELEHEEKQIMLRSLKNRQN LFKQEGMLTLVSCCIDRLNVYNSAAHFGECAGAEAGASWKDILNLLYELLAALIRGNRNN CTQFSNNLDWLVSKLERLESSSGILEVLHCILIESPEALNIIQRGHIKSIISLLYKHGRN HKILDVLCSLCVCNGVAVRANQNLICDHLLPKRDLLLQTRLVNDVQSMRPNIYLGMSEGS AQYKKWYYELMIDQVDHFLTSDPSHLRVGWATNKGYAPYPGGGEGWGGNGVGDDLYSYGF DGLHLWSGRISRAVASINQHILTSEDVVSCCLDLGAPSISFRINGQPVQGMFENFNIDGL FFPVVSFSAGVKVRFLMGGRHGDFKFLPPSGYAPCYEALLPKEKMKVEPVKEYKRDMEGV RDLLGTTQFISQASFIPTPVETSQVTGIVMPPYLEKVRDRLAENIHELWAMNKIELGWSY GKRIRDDNKRQHPCLVDFPRLPETEKNYNLQMSTETLKTLLALSCHVVQVNANAEEDLKK IKLPKNYMMSNGYKPTPLELSDVKLTPGQELLVDKLAENAHNVWAKDRIKQGWTYGIQQD VKSKRNPRLVPYSLLDERTKKSNRDSLREAIRTLIGYGYNIEPPDQEGAGHAGDRLSIDK IRFFRVERTYAVMTGKWYFEFDVVTGGDMRVGWARPGCRPDVELGTDELAFVFDGYKGQR LNMGSRFFGRCWHAGDVVGCMINMEDKSMIFTLNGEILITNKGSELCFADFETEDGFIPV CSLGLSQVGRMNLGKDASTFKYYTMCGLQEGFEPFAVNMNREVTMWFSKRLPTFVNVPKN HNHIMVTRIDGTIDSPPCLKVSHRTFGTQNSNGDMVYCRLSMPVEFHSFFKTSPVMDMNG VHEDHESLKLKHRHPLKSMRHSHDGIRGTDYSNISTYHYSVRVFAGQDPSCVWVGWVTPD YHYYSNHFNLSKNRTVTVTLGDQRGRVHESVRRSNCYMVWGGDVTSSGHSSSRSNVDLEI GCLIDLATGLVTFTGNGKELATSYQVEPNTKLFPAVFVRPTSPNLFQFELSKIKNAMPLS AAIFKSEHKNPVPQCPPRLDIQTINSVLWSRMPNTFLKVETARVSERHGWVVQCLEPLQM LAVHIPEENRCVDIMELSEQEDLRKFHYHTLKLYCALCALGNTRVAHALCSHLDQSQLLY TIDNQYLSGMLREGFYNILISIHLETAKEARLMMNNEFIIPITTETRSIRLFSDASKHHS PPGVGLSTSLKPRLSFYPPCFISTRREQHLYSPQIPLDALKEKAITMLTEAVQGGGHHIR DPVGGSVEYQFVPILRLIGTLLTMGVLGSQDVHKILLLIDPNVFVEHSEEAVAVVMEATE KEGLTGTEEKAVEAGEEEAAKEAKLPMKGLLEKRLPEPVKRQMCELLHYFCDCELKHRIE AIVSFSDSFVSKLQYNQKFRYNELMLALNMSAAVTAKKTKEFRSPPQEQINMLLNFSTGE DCPCPEDIQEELYAFHNELRLHCGIPMEEEEDEQDTSIKGRLLALVYKIKGQPLKTEEEP TEQEQQAPSNLKELISQTMVSWAQECHVQDPELVRVMFSLLRRQYDSIGELLRAMRKSYT ISAASIQDTINLLASLGQIRSLLSVRMGKEEEKLMIDGLGDIMNNKIFYQHPNLMRVLGM HETVMEVMVNVLGGGKSQEIAFPKMVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSV GLASPAMRGSTPLDVAASSVMDNNGLALALEEPDLDKVVTYLAGCGLQSCPMLLDKGYPD IGWNPIEGERYLSFLRFAVFVNGESVEENSSVVVKLLIRRPECFGPALRGEGGNGLLAAM KEAIKISEDLALDLPSSAQGVSSDVSAEDDEEEEVVHMGNAIMSFYSALIDLLGRCAPEM HLINKGKGEALRIRAILRSLVPTEDLVGIISIALKMPVIHKDGTVTEPDMAASFCPDHKA PMVLFLDRVYGIEDQSFLLHLLEVGFLPDLRASASLDTEVLSTTETALAMNRYIGSAMLP LLTRCAPHFAGTEHYATLIDSTLHTIYRLSKGRSLTKAQRDAIEECLLAVCRYLRPSMLQ QLLRRLVFDVPLLTEYCKMPLRLLTNHYEQSWKYYCLPSGWGSYGMASDEELLLTKKIFW GVLDSLSQRKYDADLFKMAMPCLSAISGALPPDYIDSTISTTLEKPASVDAQGNFDPKPI STANISLPEKLENVANKYAEHSHDKWSAEKVMLGWKYGDCIDEKAKTHPQLRTYKGLTEK EKEIHRLPVRETLKSMLAMGWNIDRTKDGETMSLRESEKMRKISQSSSQGNSFNPTPIDT SNVVLSRQLQGMMEVVAENYHNIWAKKKKNDLGIRGGATHPLLVPYDTLTAKEKARDKEK AQDMFRFLQINGYAITRGLKDMEQDSSSMEKRFAYKFLKKLLKYVNSAQEFIAHLEAMAT SGKTDKSPHEQEIKFFAKVLLPLIDQYFKNHCLYFLSSPSKNLSSSGYASNKEKEMVTSL FCKLAALVRHRISLFGSDSTTMVSCLHILAHTLDTRTVMKSGSELVKAGLRTFFENAAED LEKTLENLKLGKFTHSRSQMKGVSQNINYTTVALLPILTALFEHITQHHFGVDLLLDDVQ VSCYRILTSLYALGTGKNIYVERQLPALGECLATLAGAMPVAFLEPLLNKHNPCSVFNTK TARERAILGMPDAVEEMCPEMPRLDVLMKDINDMSESGARYTEMPHVIEVVLPMLCNYLS YWWEKGPENQASPHSGGSVCSTTVTSEHLSLILGNILKILNSNLGIDEASWMKRIAVYAQ PIISKARAVLLKSHFLPTLEKLKKKTVKVVSEEELLKADSKGDTQEAELLILDEFAVLCR DLYAFYPMLIHYVDNNRSRWLKEPDADSNELFRMVAEIFILWCKSHNFKREEQNFVVQNE INNLSFLTGDSKTKMSKSGGQDQERKHKRKRGEFYSIQTSLIVAALKKMLPMGLNMCTPG DQELISLAKTRYLLKDTDDEVKEHVRQNLHLQEKSDDPAVRWQLNLYKDVMVKNEGPPDP ERTVFRVQSISAAVFHLEQVEQPLRSKKCVWQKLLSKQRKRAVVACFRMAPLYNLPRHRS INLFLLGYQRIWIETEMYSFEEKLVQDLAKTQLKVEEEEEEEAEMQPDPLHQLILHFSHN ALTERSSLEEDPLYIAYADMMAKSCAEDEEEEDEEGKEKTFEEKEMEKQKTLYQQARLHD RGAAEMVLQMISASKGTLGPMVTFTLKLGISILNGGNILVQQKMLDYLKEKGDAGFFKSL SGLMQSCSVLDLNAFERQNKAEGLGMVTEEGSINVSERGSKVLQNDEFTKDLFRFLQLLC EGHNNDFQNFLRTQTGNTTTVNIIISTVDYLLRLQESISDFYWYYSGKDIMDEAGQRNFS KALAVAKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDSSQIEL LKELLDLQKDMIVMMLSLLEGNVVNGTIGKQMVDTLVESSSNVEMILKFFDMFLKLKDLT TSDNFKEYDPESKGVISKKEFQKSMENQKQYSQSEIEFLLSCAEADENDMFNYEEFVKRF HEPAKDIGFNVAVLLTNLSEHMPHDARLATFLDLAESVISYFEPYLGRIEIMGGAKRIER VYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGESEKMELFVNFCEDTIFEMQLASQIS EPDAVERPEEDDEDSQSVTEEPEEEEEESMMESHSAFTNSCVSMRKNLSSFRQLLTFKSM RRQYRRFRKMSVREMVQGFFSFFWMIIMGLFRFLYNLVWGFFHILWSSMFGGGLVEGAKN MKVTDILGNMPDPTQFGIHGDVLETEKMEASEASSVAEMGHMGQGDKAEADLMAELLNIQ TKSQGGKHAPEPGLGDMGEVVGVDAPSLASAVKQKKAKDSMCFLKEAATKEPTNGDHKAE PEKADPEDGEKKDQDKVKEEAPPEPLPEEKKAPKKRPGLKKESPEEFMASFFSSLDIYQT KMLNYLARNFYNLRFLALFVAFAINFILLFYKVTGDDRDDDDPDPWNGGGATDEEEDEGG MEYFVLQESTGYMAPTLRFLAILHTVISFLCVVGYYYLKVPLVVFKREKEIARKLEFDGL YITEQPSDDDIKGQWDRLVINTPSFPNNYWDKFVKRKVINKYGDLYGAERIAELLGLDKS ALDFNPTEETVVKEASLVSWLSSIDTKYQCWKMGVVFTDNSFLYLVWYTTMSILGHYNNF FFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSE DDNQPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDPYELYRILFDITFFFFVIVI LLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTTPHGFETHTLQEHNLAN YLFFLMYLINKDETEHTGQESYVWKMYQERLWDFFPAGDCFRKQYEDQLG NT seq 14733 nt NT seq  +upstreamnt  +downstreamnt atggctgaaggtggtgaaggggaagatgaaattcagttcttgagaactgatgatgaagtg gtgctccagtgtgtcgcctgcatccacaaggagaatcgcaagttctgcctgacagcagag gggctcggcaatcgactgtgctaccttgaacccacatcagaggcaaagtatgtccctcca gacctatgcatctgcaactttgtgctggagcagtctctttctgtgcgggccctgcaggag atgctggctaagactggccagaacagtgaagggcctcgaggaaaggaccgatgggcggct cagggcggtggacacagaacacttctgtatggacacgccatcctcctgaggcactccttt agcgctatgtatctgacctgtttgaagacttcaaggtcacagacggataagttgtcattt gatgtggggctgcagcaggactcaacaggtgaagcctgttggtggaccatccatcctgct tccaaacagaggtcagagggcgagaaggtacgcatcggagatgacctcatccttgtcagc gtgtcatcagaacgataccttcacctgtccatctccaatggcaacatccaggtggacgcg tccttcatgcagactctgtggaacgtccaccccacctgctccggcagcaacgtggaggag ggttacctgctgggtggccatgtgttgcgtctgttccacggtcatgatgaggttttgacc atcccagggtctgaccagagtgatcagcaacagaggatagtgaactatgagacggggaat gcaggagccaaggccaggtctctgtggaggctggagcctctcagaatcagctggagcggg agtcacattcgctggggtcagcccttccgtctccgccacctcaccacggggcactacctg tccctgacggaggagaggggggtggtactgcaggaccgggagaagtctgacacttcctcc accgccttctgcttcagagcctccaaggaaaagctggagtcgagcccaaagcgggacatc gagggcatggggatggcagagattaagtatggggactcaatctgcttcgtcatgcatgtg gccacaggactctggctgtcctaccaggcgcctgatgtaaaatcatctcgcctgggccct ctcaagagacgggcctgcctccactctgagggtcatatggatgatgggctgaccttgcag cggtgtcagcacgaagagtcccgtgctgctcgcatcatccgtaacaccacccgcctcttc agtcacttcatcagagacctggactgtctggggggaaagaaccgtgcgtcagtagccctg cccatcgaggaggtcctccagaccctcaatgacctcatcacctacttccaggtgcctaat gctgagctggagcacgaggagaaacagatcatgctgcgctctctcaagaaccgacagaac ctcttcaaacaggaaggcatgctgactctggtgtcctgctgcatcgaccgtctcaatgtg tacaacagtgcagcccactttggggagtgtgccggggcagaggctggggcttcctggaag gacatcctcaacctgctctatgagctgctagcggcgctgatccgaggcaacaggaacaac tgcacccagttctccaacaacctggactggctggtcagcaagctggagagactggagtcc tcctcaggcatactggaggttctccactgcattctaattgagagcccggaggctctaaat atcatccagagaggacatatcaagtccatcatctccctgctctacaaacatggacgcaac cacaagattttggatgtgctctgttccctctgtgtgtgtaatggggtggcagtacgagcc aatcagaacctcatctgcgatcacctgctccccaaaagagatctgcttctccagacccga ttggtcaatgacgtccaaagcatgaggcccaacatttacctgggaatgagtgagggctcg gcccagtataagaagtggtactacgagttgatgattgatcaggtggaccacttcttgacc agcgacccctctcacctgcgtgtgggctgggccaccaacaagggttacgccccttaccca ggtggaggggagggttgggggggcaacggggtgggggatgacctctactcttacggcttt gacggacttcatctctggtcaggtcgtatctcccgggcggtggcttctattaaccaacac atcctgacctctgaggatgtggtgagctgttgtctggacctgggagcccccagcatctcc tttaggatcaatggacagcccgtacagggcatgttcgagaacttcaacatcgatggactc ttcttccctgttgtcagcttttccgctggggtcaaggtgcgtttcctgatgggcggtcgt catggtgacttcaagttcctgcctccgtcgggctatgctccgtgttacgaagccctactc cccaaggagaagatgaaggtggagccggtgaaggagtacaaaagggacatggagggggtc cgagacctgctggggaccacacagttcatatctcaggcctccttcatacccacccctgtg gagaccagccaggtaacagggatcgtcatgccgccatacctggagaaggtccgggacaga ctggctgagaatatccacgagctgtgggccatgaacaagatagaactgggctggtcttat gggaagaggataagggacgataataagcggcagcacccctgccttgtggattttcccaga ctgcctgaaacggaaaagaattacaacctacagatgtcaacggaaaccttgaagactctg ctggcattaagctgccatgttgtccaggtcaacgccaacgctgaagaggacctgaagaag atcaaactcccaaagaactacatgatgtcgaatggttacaagcccacaccactggagctg tctgatgtgaagctgaccccaggccaggaacttctggtggataaactggcggagaacgcc cacaacgtgtgggccaaggacaggatcaaacaaggatggacctatggcattcagcaggat gtgaagagcaagcggaaccctcgcctggtgccatattctttattagacgagcgcactaag aagtccaacagggacagcctccgtgaggccatccgcactctgattggatacggatacaat atcgaacctccagatcaggagggcgcaggccatgcgggggacagactgagcatcgacaag atccgtttcttccgtgtggagaggacgtacgcggtgatgacggggaagtggtactttgag tttgacgtggtgacagggggagacatgcgtgtgggctgggccagacctggatgtaggcct gatgtagagctgggcactgatgagctggcctttgtcttcgacggatacaagggtcaacgt ctgaacatgggcagtcgtttctttgggcggtgttggcacgcgggggacgtggtgggctgt atgatcaacatggaggacaagtctatgatcttcaccctcaacggagagatcctcatcacc aacaagggctctgagctctgctttgccgacttcgagacggaggacggttttatcccagtg tgtagtctgggcctgtcccaggtgggtcgtatgaacctggggaaggacgccagtaccttt aagtactacaccatgtgtggcctgcaggagggcttcgaacccttcgccgtcaacatgaac cgtgaggtcaccatgtggttcagcaaacgcctccccacctttgtcaatgtgccaaagaac cacaaccacataatggtgaccagaatagatggcaccatcgacagccctccatgtctgaag gtgagccacaggacgtttgggacccagaacagtaacggtgacatggtgtactgtcgactg agcatgcccgtggagttccactccttcttcaagaccagccctgtcatggacatgaacgga gtgcatgaagatcacgagtccctcaaactgaaacacagacatccattgaagtctatgaga cacagtcatgatggaatacgaggaacagattacagcaacatcagcacgtaccactactct gtcagggtgttcgctggtcaggatccatcctgtgtgtgggtgggctgggtcacccccgac taccattactatagcaaccacttcaacctcagtaagaaccggacggtgacggttaccctg ggagaccagcgtgggcgggtccatgagagtgtgaggaggagtaactgctacatggtgtgg ggtggggacgtcaccagctcaggtcactcgtccagtcgcagtaatgtggacctggagata ggctgtctcattgacctggccactggcctggtgaccttcactggcaacggcaaggagctg gccacctcctaccaggtggaaccaaacacaaagctgtttcctgctgtgtttgtgcgaccg accagccccaacctcttccagtttgagctgtccaagataaagaatgccatgcccctgtca gctgccatctttaagagtgagcataagaacccagtaccccagtgccctccgaggctggac atccagaccatcaactcagtgctgtggagtcgcatgcccaacaccttcctgaaggtggag acggccagggtcagtgagagacacggctgggtggtgcagtgtctggagcccctgcagatg ctggctgtgcacatacctgaggagaacaggtgtgttgacatcatggagctgtctgagcag gaggacttgaggaagttccactaccacaccctgaagctgtactgtgccctgtgtgccctg ggaaacactcgcgtggcacacgccctctgcagccacctggaccaatcccagctgctctac accatcgacaaccagtatctgtcgggcatgctgcgcgagggcttctacaacatcctgatc agcattcacctggagacggccaaggaggcccgcctcatgatgaacaacgagtttatcatc cccatcaccaccgaaacgcgcagcatccgcctgttctccgatgcctccaagcaccactct cctcccggggtgggcctcagtacctccctgaagccccggctcagcttctaccccccctgc ttcatcagcaccaggagggagcagcacctgtacagcccccagatccccctggatgccctg aaggagaaggccatcaccatgctgaccgaggccgtgcagggcggtgggcatcacatcagg gaccctgtagggggcagcgtggagtaccagtttgtgcccatcctgaggctgattggtaca ctgctcaccatgggcgtgctgggcagtcaggatgttcataagatcctgctcctcatcgac cccaacgtgtttgtggagcatagcgaggaggccgtcgccgtggtgatggaggccacagag aaggaggggctgacgggcaccgaggagaaggcggtggaggccggggaggaggaggcggcc aaagaggccaagctgccaatgaaaggtctgctggagaagaggctgcctgagccagtgaaa cgacagatgtgtgagctgctgcactacttctgtgactgtgagctgaagcatcgcatcgag gccatcgtgtccttctcagacagctttgtctccaagctgcagtacaaccagaagttcagg tacaacgagctgatgctggccctcaacatgtctgctgccgtcaccgccaagaagaccaag gagttccgctcccctccccaagaacagattaacatgctgttgaacttcagtacgggggag gactgcccgtgtccagaggacattcaggaggagctctatgccttccacaacgagctgcgg cttcattgtggaatccctatggaggaagaggaagatgagcaggacacgtctattaaaggt cgtctgctggccctggtctacaaaatcaaaggtcaacctctgaagactgaagaggagccc acggagcaggaacagcaagctccctccaaccttaaagagctgattagccagaccatggtg agctgggctcaggagtgccacgtccaggaccccgagctggtcagagtgatgttcagcctg ctgaggagacagtacgacagcattggagagctgctccgggccatgaggaagagctacact atcagtgctgcctctatacaggacaccatcaacctgctggcttctctgggtcagatcaga tcactgctgtccgtacgcatgggcaaggaggaagagaaactcatgatcgacggtctgggt gacatcatgaacaacaagatattctaccagcaccccaacctgatgcgcgtgctgggcatg catgagacggtgatggaggtgatggtcaacgtgctgggaggaggcaagtcccaggagata gcgttccccaagatggtggccagctgctgtcgcttcctgtgttacttctgcaggatcagt cgtcagaaccagaaggccatgtttgaccacctcagctacctcttggaaaacagcagcgtg ggcctagcgtccccggccatgaggggctctactcctctagacgtggctgcctcctctgta atggacaacaacggcctggccttggccctggaggaacccgacctggataaggtggtgacg tacctagcaggctgtgggctccagagctgtcccatgctgctggacaaaggttaccctgac atcggttggaaccccatagagggcgagcgctacctctccttcctgcgctttgctgtcttt gttaatggtgagagtgtggaggagaactccagtgtggtggtgaagctactgatcaggcgt ccagagtgttttggtccggccctgagaggagaggggggtaacgggctgctagcagccatg aaggaggccatcaagatctctgaggaccttgctctggacctgccctcctctgcccagggg gtcagctctgacgtgtctgctgaggatgatgaggaggaagaggtggttcacatgggaaat gccatcatgtccttctactctgccctcatcgacctattgggacgctgtgccccagagatg cacttgattaacaaggggaaaggggaagccctgcgcatccgtgccatcctgcgctcccta gtgcccactgaagacctggtgggcatcatcagcatagccctcaagatgcctgtcattcac aaagacggcactgtgacagagcctgatatggcggccagtttctgcccggaccacaaggcc cccatggtgctattcctggaccgggtctatggtatcgaggaccaaagcttcctacttcac ctgctggaagtgggcttcctgccagacctgcgagcctctgcttctctggacacggaggta ctcagcaccacagagacagctctggccatgaacaggtacattggctccgccatgcttccc ctgctcacccgctgtgccccccacttcgctggcacagagcactacgccacactaatcgac tccacgctacacaccatctacaggctgtccaagggccgctcgctcaccaaggcccagaga gatgctattgaggaatgtctgctggctgtctgcaggtacctccgcccctccatgctgcag cagctcctgcgccgcctggtctttgacgtgcccttgctgacagagtactgcaagatgcct ctcaggctcttgaccaaccactacgagcagagctggaagtactactgtctgccgtcaggc tggggcagctacggcatggcctcagacgaggaactgctcctcacaaagaagatcttctgg ggtgtcttggattcgctctcacagaggaagtacgatgcagatctctttaagatggccatg ccctgtctgagtgccatatctggggccttaccgcctgactacatagactccaccatcagc accaccctggagaagcctgcgtctgtggacgcgcagggcaacttcgaccccaaacccatc agcacagccaacatatctcttccagagaaactggaaaatgttgccaacaaatatgctgag cattcccatgacaaatggtcagcagagaaggtgatgttgggatggaagtacggagactgt atagatgagaaggccaagactcaccctcagctcaggacctacaaaggcctcacagagaag gagaaggagatccacaggttgccggtgagggagactctgaagagcatgctggctatgggc tggaacattgacaggaccaaggatggagagaccatgtccctacgggagagtgagaagatg cggaagatctcccagtcctcctctcagggtaacagtttcaacccaacaccaatagacacc agcaatgtggttctgtctagacagttacagggcatgatggaggttgtggctgagaattat cacaacatctgggctaagaagaagaagaatgaccttggaattagaggtggggcaactcac cctctgctagtgccctatgacaccctgactgccaaagagaaggcccgggacaaagagaag gcccaggacatgttccgcttcctgcagatcaacggctacgccatcaccagaggtctgaag gatatggagcaggactcttcctccatggagaagaggtttgcctacaagttcctcaagaag ctcctcaagtatgtgaactcagcccaggagttcatcgcccaccttgaggccatggctacc agtggtaagacagacaagtcacctcatgagcaagaaatcaagtttttcgccaaagtcctc ctccctctgatagaccagtacttcaagaaccactgtctctacttcctgtcttctcccagt aagaacctgagcagcagcggctatgcatctaataaggagaaggagatggtcaccagcctg ttctgtaaactggcagctcttgtcagacacaggatttccctctttgggagtgactccacc accatggtgagctgtctccacatcctggcccacacactggacaccaggacggtgatgaag tctggctcagagctggtgaaggcggggttaaggacgttcttcgagaacgcagcggaggac ctggagaagacccttgagaacctgaagttggggaagttcacccactcccgctcacagatg aagggcgtgtcccagaacattaactacaccacggtggcactactgcccatcctcactgcc ctgtttgaacacatcacccagcaccactttggagtggacctgctcttggatgatgtccaa gtgtcatgctatcgtatcttgaccagcctctatgcactcgggactggaaaaaacatctat gtggaaaggcagctgccggccctgggggagtgtctggccaccctggcaggcgccatgcct gtggccttcctggagccactgctcaacaaacacaacccctgctctgtgttcaacaccaag actgcccgcgaacgtgccatcctaggcatgccagacgcagtggaggagatgtgtccggag atgcctcgtctagacgtcctgatgaaggacatcaacgacatgtctgagtctggggcgcgc tacacagagatgccccatgtcatcgaggtggtgctgcccatgctgtgtaactacctgtcc tactggtgggagaagggcccagagaaccaggcgtctccgcacagtgggggcagtgtgtgt tccaccaccgtcacctcagaacatctcagcctcatcctgggaaacatcctgaagatcctc aacagcaacctgggcatcgacgaggcctcctggatgaagaggatcgcagtgtacgcccag cccatcatcagtaaggccagggctgttctgttgaagagtcacttcctgcctacgctggag aagctgaagaagaagaccgtgaaggtggtgtcggaggaggagctactgaaggctgacagt aagggagacacccaggaggctgagctcctcatcctggatgagttcgctgtgctctgcaga gacctctacgccttctacccgatgctcatccattacgtagacaataacaggtccaggtgg ctgaaagaaccagacgctgactccaatgaactcttcagaatggtggctgagatcttcatt ctctggtgcaaatcacataacttcaaaagggaagagcagaactttgtggttcagaatgaa atcaacaacctgtctttcctgactggtgatagcaagacgaagatgtcaaagtcagggggt caggaccaggagaggaagcataagaggaagcgaggagagttctactccatccagacctcc ctgatcgttgctgccctgaagaagatgctgcccatgggactcaacatgtgcacccccggg gaccaggagctcatctccctggccaagacacgttacctcctgaaggacacagatgatgaa gtgaaggaacatgtgcggcaaaatttgcaccttcaagaaaagtcagacgaccctgcagtg aggtggcagctgaacctgtataaggatgtgatggtgaagaacgaggggcctccagaccct gagaggacagtgttcagagtccagagcatatcagctgcagtctttcatctggagcaggtg gaacagccgttgaggtctaagaagtgtgtgtggcagaagctgctgtccaagcagagaaag cgtgcggtggtggcctgcttccgcatggctcctctctacaacctgcccaggcatcgctct attaacctcttcctcctgggctatcagagaatatggatagaaacagagatgtactctttt gaagagaagctagtgcaggacctggcaaagacccaactgaaggtggaagaggaggaagag gaggaggcagagatgcagccagaccctcttcatcagctcatcctgcatttcagtcacaat gcgctcactgagcggagttctttggaagaggatcctttgtatattgcgtatgcagacatg atggcaaagagttgtgcagaagatgaagaagaagaagatgaagaaggaaaagagaaaacg tttgaggaaaaagagatggagaaacagaagactctgtaccagcaggccaggctgcatgac agaggagctgctgagatggtgttacagatgatcagcgccagcaaaggtacgcttgggccc atggtgacctttaccttgaagctgggcatctctatactcaacggaggcaacatactggtt cagcagaaaatgcttgactatctgaaggaaaaaggagatgctggctttttcaaaagtttg tcaggactcatgcagtcttgcagtgtcctggatttgaatgcattcgaaaggcaaaacaaa gcggaaggtcttgggatggtgactgaggaaggatcaatcaacgtgagtgagcggggttcc aaagtactgcaaaacgatgagttcactaaggatctctttaggtttctgcaactgctctgt gagggacacaacaacgacttccaaaacttcctgcggactcaaacagggaacacgaccacc gtaaatatcatcatcagcactgtggactacctgcttcgactgcaggaatccatcagtgat ttctactggtactactctgggaaagacatcatggatgaggctggccagcggaacttctcc aaagccctggctgtggccaagcagattttcaactctctcactgagtacatacagggcccg tgtattgggaaccagcagagtctggcacacagcaggctatgggatgcagtggtgggattc ctgcatgtgtttgccaatatgcagatgaagctgtcacaggattcaagtcagattgagtta ttgaaggagctgctggacctgcagaaggacatgatcgtgatgatgctctcccttctggaa ggaaacgttgtcaacggaaccatcgggaaacagatggtggacaccctggtggagtcctcc agcaatgtggagatgatcctcaagttcttcgacatgttcctcaaactcaaagacctgacc acctcggacaacttcaaggagtatgacccagagagcaagggagtgatctccaagaaggag ttccagaagtccatggagaatcagaagcagtactcccagtcggagatcgagttcttgctc tcctgcgccgaggctgacgagaacgacatgttcaactacgaggagtttgtgaagcgcttt catgagccggccaaggacattggctttaacgtggcggtcctgctcaccaacctgtcagaa cacatgcctcacgatgcccgtctggccaccttcctggacctggctgagagcgtgataagc tacttcgagccctacctgggccgcatagaaattatgggcggagccaagcgcatcgagagg gtctactttgagatcagcgagtctagtcgtacacagtgggagaagccccaagtcaaagag tctaagagacagtttatctttgacgtggtgaatgagggtggagagagcgagaagatggag ctgtttgtcaacttctgtgaggacaccatatttgagatgcagctggcctcacagatctct gagcctgacgcagtggagcgtcccgaggaggacgacgaggacagccagagtgtgacggag gagccagaggaggaagaggaggagagcatgatggagtctcactccgccttcaccaactcc tgcgtctccatgaggaagaacctgtccagcttccgccagctgctgaccttcaaaagcatg aggcggcagtacaggaggttcaggaagatgagtgtgagggagatggtccaaggcttcttc tcattcttctggatgattatcatgggcctcttccgcttcctttacaacctggtgtggggc ttcttccatatcctgtggtcctccatgtttggcgggggcctggtggagggggccaagaac atgaaggtcacagacatcctggggaacatgcccgaccccacacagtttggtatccatggt gacgtgctggagacagagaagatggaggcgagtgaggcgtcatctgtggcagagatgggc cacatgggccagggggacaaggcagaggcagatctgatggctgagctgcttaacatccaa accaagagccaggggggaaagcatgcgcccgagccaggtctgggggacatgggtgaggtg gtgggggtcgacgccccctctttagccagtgccgtcaagcagaagaaggccaaggattcc atgtgtttcttgaaggaggctgcgactaaggagcctaccaacggagatcacaaagccgag ccagagaaagcagacccagaggatggggagaagaaggaccaggacaaagtcaaagaggag gctcccccagagcccttaccggaggagaagaaggcccccaagaagagaccgggactgaag aaagagtctccagaggagttcatggccagcttcttctctagcctggacatctaccagacc aagatgctgaactatctggccagaaacttctacaacctgcgtttcttggcattgtttgtt gcatttgccataaactttattctgctcttctacaaagtgactggagatgacagggatgac gatgatccagatccctggaatggaggtggagctactgatgaagaggaggatgaaggtggg atggagtattttgtcctgcaggagagcacaggctacatggcacctacactgcgcttcttg gccatactacacacagtcatctctttcctgtgtgtggtgggatactactacctaaaggta cctctggtggtgttcaagagagaaaaggagatcgccaggaagttggagtttgacggcctc tacatcacagagcagccgtcagacgatgacatcaaaggacagtgggaccgcctcgtcatc aacaccccttccttccctaataactactgggacaagtttgtgaaacgcaaggtgatcaat aagtacggagatctgtatggagccgagaggatagcagagctgctggggctggataagagt gctctggacttcaaccccacagaggagacggtggtgaaggaggcatcgctggtgtcctgg ttgagctctattgacaccaagtaccaatgctggaaaatgggtgtggtgtttacagacaat tcgttcctgtacctggtgtggtacaccaccatgtccatcctgggtcactacaacaacttc ttcttcgctgcccatctgttggacatcgccatgggcttcaagaccctccggaccatcctg tcctcggtcacccacaatggcaaacagctggttctgactgtaggtctcctggcggtggtg gtctatctgtacactgtggtggccttcaacttcttccgcaagttctacaacaagagtgag gatgacaaccagcccgatatgaagtgtgacgacatgatgacttgctacctgttccacatg tatgttggtgtgagggcaggtggtggaatcggggatgagatcgaggaccctgcgggcgac ccgtacgagctctaccgcatcctcttcgacatcaccttcttcttctttgtcatcgtcatc ctgctggccatcatacagggtctgatcattgatgcttttggagagctgagagaccaacag gagcaagtgaaagaggatatggagaccaaatgtttcatctgtggcatcggtaatgactac tttgacacgacgcctcacggctttgaaacacacaccttacaagagcacaacttggccaac tacctgtttttcctgatgtaccttatcaacaaagatgagacggaacacacaggtcaggag tcatacgtgtggaagatgtaccaggagaggctctgggactttttccctgctggagactgt ttcagaaagcagtatgaggaccagcttggatag

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