KEGG   Staphylococcus aureus subsp. aureus Mu50 (MRSA/VISA): SAV0731
Entry
SAV0731           CDS       T00052                                 
Symbol
nrdE
Name
(GenBank) ribonuceloside diphosphate reductase major subunit
  KO
K00525  ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
Organism
sav  Staphylococcus aureus subsp. aureus Mu50 (MRSA/VISA)
Pathway
sav00230  Purine metabolism
sav00240  Pyrimidine metabolism
sav01100  Metabolic pathways
sav01232  Nucleotide metabolism
Module
sav_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
sav_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:sav00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    SAV0731 (nrdE)
   00240 Pyrimidine metabolism
    SAV0731 (nrdE)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:sav03400]
    SAV0731 (nrdE)
Enzymes [BR:sav01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1  ribonucleoside-diphosphate reductase
     SAV0731 (nrdE)
DNA repair and recombination proteins [BR:sav03400]
 Prokaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    SAV0731 (nrdE)
SSDB
Motif
Pfam: Ribonuc_red_lgC RNR_N Ribonuc_red_lgN UvrB_inter RNR-II_ins_dom Caud_tail_N InlK_D3
Other DBs
NCBI-ProteinID: BAB56893
UniProt: A0A0H3JU13
LinkDB
Position
807613..809769
AA seq 718 aa
MEKTKTLLNLRTRWVILMKTMEEKKYNHIELNNEVTKRREDGFFSLEKDQEALVAYLEEV
KDKTIFFDTEIERLRYLVDNDFYFNVFDIYSEADLIEITDYAKSISFNFASYMSASKFFK
DYALKTNDKSQYLEDYNQHVAIVALYLANGNKAQAKQFISAMVEQRYQPATPTFLNAGRA
RRGELVSCFLLEVDDSLNSINFIDSTAKQLSKIGGGVAINLSKLRARGEAIKGIKGVAKG
VLPIAKSLEGGFSYADQLGQRPGAGAVYLNIFHYDVEEFLDTKKVNADEDLRLSTISTGL
IVPSKFFDLAKEGKDFYMFAPHTVKEEYGVTLDDIDLEKYYDDMVANPNVEKKKKNAREM
LNLIAQTQLQSGYPYLMFKDNANRVHPNSNIGQIKMSNLCTEIFQLQETSIINDYGIEDE
IKRDISCNLGSLNIVNVMESGKFRDSVHSGMDALTVVSDVANIQNAPGVRKANSELHSVG
LGVMNLHGYLAKNKIGYESEEAKDFANIFFMMMNFYSIERSMEIAKERGIKYQDFEKSDY
ANGKYFEFYTTQEFEPQFEKVRELFDGMAIPTSEDWKKLQQDVEQYGLYHAYRLAIAPTQ
SISYVQNATSSVMPIVDQIERRTYGNAETFYPMPFLSPQTMWYYKSAFNTDQMKLIDLIA
TIQTHIDQGISTILYVNSEISTRELARLYVYAHYKGLKSLYYTRNKLLSVEECTSCSI
NT seq 2157 nt   +upstreamnt  +downstreamnt
atggaaaaaacaaagacgttattgaatttaagaacaaggtgggtaattttaatgaaaacc
atggaagagaaaaagtacaatcatattgaattaaataatgaggtcactaaacgaagagaa
gatggattctttagtttagaaaaagaccaagaagctttagtagcttatttagaagaagta
aaagacaaaacaatcttcttcgatactgaaatcgagcgtttacgttatttagtagacaac
gatttttatttcaatgtgtttgatatttatagtgaagcggatctaattgaaatcactgat
tatgcaaaatcaatctcgtttaattttgcaagttatatgtcagctagtaaatttttcaaa
gattacgctttgaaaacaaatgataaaagtcaatacttagaagactataatcaacacgtt
gccattgttgctttatacctagcaaatggtaataaagcacaagctaaacaatttatttct
gctatggttgaacaaagatatcaaccagcgacaccaacatttttaaacgcaggccgtgcg
cgtcgtggtgagctagtgtcatgtttcttattagaagtggatgacagcttaaattcaatt
aactttattgattcaactgcaaaacaattaagtaaaattgggggcggcgttgcaattaac
ttatctaaattgcgtgcacgtggtgaagcaattaaaggaattaaaggcgtagcgaaaggc
gttttacctattgctaagtcacttgaaggtggctttagctatgcagatcaacttggtcaa
cgccctggtgctggtgctgtgtacttaaatatcttccattatgatgtagaagaattttta
gatactaaaaaagtaaatgcggatgaagatttacgtttatctacaatatcaactggttta
attgttccatctaaattcttcgatttagctaaagaaggtaaggacttttatatgtttgca
cctcatacagttaaagaagaatatggtgtgacattagacgatatcgatttagaaaaatat
tatgatgacatggttgcaaacccaaatgttgagaaaaagaaaaagaatgcgcgtgaaatg
ttgaatttaattgcgcaaacacaattacaatcaggttatccatatttaatgtttaaagat
aatgctaacagagtgcatccgaattcaaacattggacaaattaaaatgagtaacttatgt
acggaaattttccaactacaagaaacttcaattattaatgactatggtattgaagacgaa
attaaacgtgatatttcttgtaacttgggctcattaaatattgttaatgtaatggaaagc
ggaaaattcagagattcagttcactctggtatggacgcattaactgttgtgagtgatgta
gcaaatattcaaaatgcaccaggagttagaaaagctaacagtgaattacattcagttggt
cttggtgtgatgaatttacacggttacctagcaaaaaataaaattggttatgagtcagaa
gaagcaaaagattttgcaaatatcttctttatgatgatgaatttctactcaatcgaacgt
tcaatggaaatcgctaaagagcgtggtatcaaatatcaagactttgaaaagtctgattat
gctaatggcaaatatttcgagttctatacaactcaagaatttgaacctcaattcgaaaaa
gtacgtgaattattcgatggtatggctattcctacttctgaggattggaagaaactacaa
caagatgttgaacaatatggtttatatcatgcatatagattagcaattgctccaacacaa
agtatttcttatgttcaaaatgcaacaagttctgtaatgccaatcgttgaccaaattgaa
cgtcgtacttatggtaatgcggaaacattttaccctatgccattcttatcaccacaaaca
atgtggtactacaaatcagcattcaatactgatcagatgaaattaatcgatttaattgcg
acaattcaaacgcatattgaccaaggtatctcaacgatcctttatgttaattctgaaatt
tctacacgtgagttagcaagattatatgtatatgcgcactataaaggattaaaatcactt
tactatactagaaataaattattaagtgtagaagaatgtacaagttgttctatctaa

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