Staphylococcus aureus subsp. aureus Mu50 (MRSA/VISA): SAV1427
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Entry
SAV1427 CDS
T00052
Symbol
thyA
Name
(GenBank) thymidylate synthase
KO
K00560
thymidylate synthase [EC:
2.1.1.45
]
Organism
sav
Staphylococcus aureus subsp. aureus Mu50 (MRSA/VISA)
Pathway
sav00240
Pyrimidine metabolism
sav00670
One carbon pool by folate
sav01100
Metabolic pathways
sav01232
Nucleotide metabolism
sav04981
Folate transport and metabolism
Module
sav_M00938
Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:
sav00001
]
09100 Metabolism
09104 Nucleotide metabolism
00240 Pyrimidine metabolism
SAV1427 (thyA)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
SAV1427 (thyA)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
SAV1427 (thyA)
Enzymes [BR:
sav01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.45 thymidylate synthase
SAV1427 (thyA)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Thymidylat_synt
LIAS_N
ASD1
Motif
Other DBs
NCBI-ProteinID:
BAB57589
UniProt:
P67046
Structure
PDB
PDBj
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All DBs
Position
complement(1508996..1509952)
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AA seq
318 aa
AA seq
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MLNSFDAAYHSLCEEVLEIGNTRNDRTNTGTISKFGHQLRFDLSKGFPLLTTKKVSFKLV
ATELLWFIKGDTNIQYLLKYNNNIWNEWAFENYIKSDEYNGPDMTDFGHRALSDPEFNEQ
YKEQMKQFKQRILEDDTFAKQFGDLGNVYGKQWRDWVDKDGNHFDQLKTVIEQIKHNPDS
RRHIVSAWNPTEIDTMALPPCHTMFQFYVQDGKLSCQLYQRSADIFLGVPFNIASYALLT
HLIAKECGLEVGEFVHTFGDAHIYSNHIDAIQTQLARESFNPPTLKINSDKSIFDINYED
LEIVDYESHPAIKAPIAV
NT seq
957 nt
NT seq
+upstream
nt +downstream
nt
atgttgaattcatttgatgcagcatatcacagtctttgtgaagaggttttagaaatagga
aatacacgaaatgatcgcacaaatacaggtacgatttcgaaatttggtcatcaacttcgc
tttgacttatctaaaggatttccactattaacgacaaagaaagtttcttttaaattagta
gcaaccgaattattatggttcattaaaggagatacaaacatccaatacttattaaaatat
aataataatatttggaacgaatgggcttttgaaaattatataaaatcagacgagtataac
ggtccagatatgacagatttcgggcatcgtgcattgagtgatcctgaatttaacgaacaa
tataaagaacaaatgaaacaatttaagcaacgtattcttgaagatgatacttttgcgaag
caattcggtgatttaggaaatgtttatggtaaacaatggcgagattgggttgataaagat
ggtaatcattttgatcaacttaaaacagtaattgaacaaattaagcataatccagattca
agacgacacatcgtatctgcatggaatccaacagaaattgatacaatggcacttccgcct
tgtcataccatgttccagttttatgtccaagatggtaagttaagttgccagttataccaa
cgtagcgcagatatctttttaggtgtgccatttaatatcgcaagctacgctttattgaca
caccttattgccaaagaatgtggacttgaagtaggagaatttgtgcatacatttggagat
gcacatatttattcaaatcatattgatgcgattcaaacacaattagcacgtgaaagcttc
aatcctccaacattaaaaattaacagtgacaagtctattttcgacataaattatgaagat
ttggaaattgttgactatgaatcacatccagcaataaaagctccaatagcagtgtag
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