Staphylococcus aureus subsp. aureus Mu3 (MRSA/hetero-VISA): SAHV_2067
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Entry
SAHV_2067 CDS
T00588
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
saw
Staphylococcus aureus subsp. aureus Mu3 (MRSA/hetero-VISA)
Pathway
saw00300
Lysine biosynthesis
saw00550
Peptidoglycan biosynthesis
saw01100
Metabolic pathways
saw01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
saw00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SAHV_2067 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SAHV_2067 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SAHV_2067 (murF)
Enzymes [BR:
saw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SAHV_2067 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BAF78950
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Position
complement(2216009..2217367)
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AA seq
452 aa
AA seq
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MINVTLKQIQSWIPCEIEDQFLNQEINGVTIDSRAISKNMLFIPFKGENVDGHRFVSKAL
QDGAGAAFYQRGTPIDENVSGPIIWVEDTLTALQQLAQAYLRHVNPKVIAVTGSNGKTTT
KDMIESVLHTEFKVKKTQGNYNNEIGLPLTILELDNDTEISILEMGMSGFHEIEFLSNLA
QPDIAVITNIGESHMQDLGSREGIAKAKSEITIGLKDNGTFIYDGDEPLLKPHVKEVENA
KCISIGVATDNALVCSVDDRDTTGISFTINNKEHYDLPILGKHNMKNATIAIAVGHELGL
TYNTIYQNLKNVSLTGMRMEQHTLENDITVINDAYNASPTSMRAAIDTLGTLTGRRILIL
GDVLELGENSKEMHIGVGNYLEEKHIDVLYTFGNEAKYIYDSGQQHVEKAQHFNSKDDMI
EVLTSDLKAHDRVLVKGSRGMKLEEVVNALIS
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattaatgttacattaaagcaaattcaatcatggattccttgtgaaattgaagatcaa
tttttaaatcaagagataaatggagtcacaattgattcacgagcaatttctaaaaatatg
ttatttataccatttaaaggtgaaaatgttgacggtcatcgctttgtctctaaagcatta
caagatggtgctggggctgctttttatcaaagagggacacctatagatgaaaatgtaagc
gggcctattatatgggttgaagacacattaacggcattacaacaattggcacaagcttac
ttgagacatgtaaaccctaaagtaattgccgtcacagggtctaatggtaaaacaacgact
aaagatatgattgaaagtgtattgcataccgaatttaaagttaagaaaacgcaaggtaat
tacaataatgaaattggtttacctttaactattttggaattagataatgatactgaaata
tcaatattggagatggggatgtcaggtttccatgaaattgaatttctgtcaaacctcgct
caaccagatattgcagttataactaatattggtgagtcacatatgcaagatttaggttcg
cgcgaggggattgctaaagctaaatctgaaattacaataggtctaaaagataatggtacg
tttatatatgatggcgatgaaccattattgaaaccacatgttaaagaagttgaaaatgca
aaatgtattagtattggtgttgctactgataatgcattagtttgttctgttgatgataga
gatactacaggtatttcatttacgattaataataaagaacattacgatctgccaatatta
ggaaagcataatatgaaaaatgcgacgattgccattgcggttggtcatgaattaggtttg
acatataacacaatctatcaaaatttaaaaaatgtcagcttaactggtatgcgtatggag
caacatacattagaaaatgatattactgtgataaatgatgcctataatgcaagtcctaca
agtatgagagcagctattgatacactgggtactttgacagggcgtcgcattctaatttta
ggagatgttttagaattaggtgaaaatagcaaagaaatgcatatcggtgtaggtaattat
ttagaagaaaagcatatagatgtgttgtatacgtttggtaatgaagcgaagtatatttat
gattcgggccagcaacatgtcgaaaaagcacaacacttcaattctaaagacgatatgata
gaagttttaacaagcgatttaaaagcgcatgaccgtgtattagttaaaggatcacgtggt
atgaagttagaagaagttgtaaatgctttaatttcatag
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