Saccharomyces cerevisiae (budding yeast): YIR034C
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Entry
YIR034C CDS
T00005
Symbol
LYS1
Name
(RefSeq) saccharopine dehydrogenase (NAD+, L-lysine-forming)
KO
K00290
saccharopine dehydrogenase (NAD+, L-lysine forming) [EC:
1.5.1.7
]
Organism
sce
Saccharomyces cerevisiae (budding yeast)
Pathway
sce00300
Lysine biosynthesis
sce00310
Lysine degradation
sce01100
Metabolic pathways
sce01110
Biosynthesis of secondary metabolites
sce01230
Biosynthesis of amino acids
Module
sce_M00030
Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
Brite
KEGG Orthology (KO) [BR:
sce00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
YIR034C (LYS1)
00310 Lysine degradation
YIR034C (LYS1)
Enzymes [BR:
sce01000
]
1. Oxidoreductases
1.5 Acting on the CH-NH group of donors
1.5.1 With NAD+ or NADP+ as acceptor
1.5.1.7 saccharopine dehydrogenase (NAD+, L-lysine-forming)
YIR034C (LYS1)
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Motif
Pfam:
AlaDh_PNT_N
AlaDh_PNT_C
Motif
Other DBs
NCBI-GeneID:
854852
NCBI-ProteinID:
NP_012300
SGD:
S000001473
UniProt:
P38998
Structure
PDB
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All DBs
Position
IX:complement(419615..420736)
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AA seq
373 aa
AA seq
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MAAVTLHLRAETKPLEARAALTPTTVKKLIAKGFKIYVEDSPQSTFNINEYRQAGAIIVP
AGSWKTAPRDRIIIGLKEMPETDTFPLVHEHIQFAHCYKDQAGWQNVLMRFIKGHGTLYD
LEFLENDQGRRVAAFGFYAGFAGAALGVRDWAFKQTHSDDEDLPAVSPYPNEKALVKDVT
KDYKEALATGARKPTVLIIGALGRCGSGAIDLLHKVGIPDANILKWDIKETSRGGPFDEI
PQADIFINCIYLSKPIAPFTNMEKLNNPNRRLRTVVDVSADTTNPHNPIPIYTVATVFNK
PTVLVPTTAGPKLSVISIDHLPSLLPREASEFFSHDLLPSLELLPQRKTAPVWVRAKKLF
DRHCARVKRSSRL
NT seq
1122 nt
NT seq
+upstream
nt +downstream
nt
atggctgccgtcacattacatctaagagctgaaactaaacccctagaggcacgtgctgcc
ttaacacctaccacggttaaaaaactgatagctaagggcttcaaaatatatgtagaggac
agtccacaatctactttcaatattaacgaatatcgtcaagcaggtgccattatagtgcct
gcaggttcatggaaaaccgctccacgcgacagaatcattataggtttgaaggaaatgcct
gaaaccgatactttccctctagtccacgaacacatccagtttgctcactgctacaaagac
caagctgggtggcaaaatgtccttatgagatttattaagggacacggtactctatatgat
ttggaatttttggaaaatgaccaaggtagaagagttgctgcctttggattttacgctggg
ttcgcaggtgcagcccttggtgtaagagactgggcattcaagcaaacgcattctgacgat
gaagacttgcctgcagtgtcgccttaccccaatgaaaaggcattggttaaagatgttacc
aaagattataaagaagccttagccaccggagccagaaagccaaccgtgttaatcattggt
gcgctaggaagatgtggttccggtgccatcgatctgttgcacaaagttggtattccagat
gctaacatattaaaatgggatatcaaagaaacttcccgtggtggtccctttgacgaaatt
ccacaagctgatatttttatcaattgtatatatctatcgaagccaattgctcctttcact
aacatggagaaactgaataatcctaacagaagactaaggaccgtggtggacgtatcagca
gacactaccaaccctcacaaccccatcccaatatacactgtggctactgtgtttaacaaa
cctaccgttctggtacctaccactgccgggcctaaattatctgtcatctctattgatcac
ttgccttctttgctgccaagagaagcttcagaatttttctctcatgatctcttaccatct
ttagagctcctacctcaaagaaaaactgctcctgtctgggttagagccaagaaattgttc
gatagacattgcgctcgtgttaaaagatcttcaagattgtag
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