KEGG   Streptomyces coelicolor: SCO5354
Entry
SCO5354           CDS       T00085                                 
Symbol
thrA
Name
(GenBank) homoserine dehydrogenase
  KO
K00003  homoserine dehydrogenase [EC:1.1.1.3]
Organism
sco  Streptomyces coelicolor
Pathway
sco00260  Glycine, serine and threonine metabolism
sco00270  Cysteine and methionine metabolism
sco00300  Lysine biosynthesis
sco01100  Metabolic pathways
sco01110  Biosynthesis of secondary metabolites
sco01120  Microbial metabolism in diverse environments
sco01230  Biosynthesis of amino acids
Module
sco_M00018  Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:sco00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    SCO5354 (thrA)
   00270 Cysteine and methionine metabolism
    SCO5354 (thrA)
   00300 Lysine biosynthesis
    SCO5354 (thrA)
Enzymes [BR:sco01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.3  homoserine dehydrogenase
     SCO5354 (thrA)
SSDB
Motif
Pfam: Homoserine_dh NAD_binding_3 ACT ACT_AHAS_ss ACT_6 ACT_4 ACT_9 DUF7217 DUF4684 Sacchrp_dh_NADP TTHA0829-like_ACT DUF4349 Usp
Other DBs
NCBI-ProteinID: CAC33918
Kitasato: SCO5354
UniProt: Q9ADB4
LinkDB
Position
5822215..5823504
AA seq 429 aa
MRTRPLKVALLGCGVVGSKVARIMTTHAADLAARIGAPVELAGVAVRRPDKVREGIDPAL
VTTDATALVKRGDIDVVVEVIGGIEPARTLITTAFAHGASVVSANKALIAQDGAALHAAA
DEHGKDLYYEAAVAGAIPLIRPLRESLAGDKVNRVLGIVNGTTNFILDAMDSTGAGYQEA
LDEATALGYAEADPTADVEGFDAAAKAAILAGIAFHTRVRLDDVYREGMTEVTAADFASA
KEMGCTIKLLAICERAADGGSVTARVHPAMIPLSHPLANVREAYNAVFVESDAAGQLMFY
GPGAGGSPTASAVLGDLVAVCRNRLGGATGPGESAYAALPVSPMGDVVTRYHISLDVADK
PGVLAQVATVFAEHGVSIDTVRQSGKDGEASLVVVTHRASDAALGGTVEALRKLDTVRGV
ASIMRVEGE
NT seq 1290 nt   +upstreamnt  +downstreamnt
atgcgtacgcgtccgctgaaggtggcgctgctgggctgtggagtggtcggctcaaaggtg
gcgcgcatcatgacgacgcacgccgccgacctcgccgcccggatcggggccccggtggag
ctcgcgggcgtcgccgtacggcggcccgacaaggtgcgggaggggatcgacccggccctc
gtcaccaccgacgccaccgcgctcgtcaagcgcggggacatcgacgtcgtcgtcgaggtc
atcggggggatcgagcccgcgcggacgctcatcaccaccgccttcgcgcacggcgcctcc
gtggtctccgccaacaaggcgctcatcgcccaggacggcgccgccctgcacgccgccgcc
gacgagcacggcaaggacctgtactacgaggccgccgtcgccggtgccatcccgctgatc
cggccgctgcgcgagtccctcgccggcgacaaggtcaaccgggtgctcggcatcgtcaac
gggaccaccaacttcatcctcgacgccatggactcgaccggggccggctatcaggaagcg
ctcgacgaggccacggccctcgggtacgccgaggccgacccgaccgccgacgtcgagggc
ttcgacgccgcagccaaggccgccatcctcgccgggatcgccttccacacgcgcgtacgc
ctcgacgacgtctaccgcgagggcatgaccgaggtcaccgccgccgacttcgcctccgcc
aaggagatgggctgcaccatcaagctgctcgccatctgcgagcgggcggcggacggaggg
tcggtcaccgcacgcgtgcatcccgcgatgatcccgctcagccatccgctggccaacgtg
cgcgaggcgtacaacgccgtgttcgtggagtccgacgccgccggtcagctcatgttctac
gggcccggcgccggcggttcgccgaccgcgtccgccgtgctcggcgacctggtggccgtg
tgccgcaaccggctgggcggagcgaccggacccggtgagtccgcgtacgccgccctgccc
gtctccccgatgggcgacgtcgtcacgcgctaccacatcagcctcgacgtggccgacaaa
ccgggcgtgctcgcccaggtcgcgaccgtgttcgcggagcacggtgtctccatcgacacc
gtgcggcagtccggcaaggacggcgaggcatccctcgtcgtcgtcacccatcgcgcgtcc
gacgccgccctcggcggtacggtcgaggcgctgcgcaagctcgacaccgtgcggggtgtc
gccagcatcatgcgggttgaaggagagtaa

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