Seriola dumerili (greater amberjack): 111237067 Help Entry 111237067         CDS       T05606                                  Symbol ryr3 Name (RefSeq) ryanodine receptor 3   KO K04963   ryanodine receptor 3 Organism sdu  Seriola dumerili (greater amberjack) Pathway sdu04020   Calcium signaling pathway sdu04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:sdu00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     111237067 (ryr3)    04020 Calcium signaling pathway     111237067 (ryr3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:sdu04040]     111237067 (ryr3) Ion channels [BR:sdu04040]  Voltage-gated cation channels   Ryanodine receptor    111237067 (ryr3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 Motif Other DBs NCBI-GeneID:  111237067 NCBI-ProteinID:  XP_022621746 LinkDB All DBs Position Unknown AA seq 4874 aa AA seqDB search MGGVGLGEGRVKFPLYTWTLVCCDYISEDDEVVLQSVATIQKEHRKFCLAAEGLGNRICY LESTSEAKYVPPDLCICNFVLEQSLSVRALQEMLANTGQSSEGSADHEKWAGQGGGHRTL LYGHAILLRHSFSSMYLTCLKTSRSLTDKLSFDVGLQEDSIGESCWWTIHPASKQRSEGE KVRIGDDLILVSVSTERYLHLSISNGNIQVDASFMQTLWNVQPTCSSGNMAVGYLIGGHV MRLCHGHDESLTIPGADKNEEEQRIVNYEAGKGASRARSLWRLEPLRISWSGSHIRWGQA FRLRHLSTGHYLALTEERGLVLQDREKSDTTATAFCFRASKEKGDSGPKRDIDGMGVPEI KYGDSVCFIMHLATGLWLSYLAPDAKSSRLGPLKRRACLHSEGHMDDGLTLQRCQHEESR AARIIRNTTFLFTNFIKALDSTAEGESTAVAGYVEEVLQTLNDLIQYFKQPDSELEHEEK QCLLRSLIKRQDLFKEEGMLALLSKCIDRMNLYNSAAHFGEMAGEEAGAAWKDILNLLYE LLASLIRGNRNNCTQFSRNLDWLISKLERLESSSGILEVLHCILVESPEALNIIQRGHIK SIISLLYKHGRNHKILDVLCSLCVCNGVAVRANQNLICDNLLPKRDLLLQTRLVNDVQSM RPNIFLGMAEGSAQYKKWYFELVIDQVDHFVTGEPTHLRVGWANTKGYAPYPGGGEGWGG NGVGDDLYSYSFDGLHLWSGRIPRAVASINQHLLNSDDVVSCCLDLGAPSMSFRINGQPV QGMFEDFNTDGFFFPVVSFSAGVKVRFLLGGRHGDFKFLPPAGYSPCYEALLPKEKMHVE PVKEYKRDHEGVRDLLGTTQFLSQASFIPTPVDTTQIVLPPHLDNVRDKLAENIHELWGM NKIELGWTYGKVRDDNKRQHPCLVDFAKLPETERNYNLQMSSETLKTLLALGCHVAQVNV HAEDDLKKIKLPKDYMMSNGYKPAPLDLSDVKLNAGQEVLVDKLAENAHNVWAKDRIKQG WTYGIQQDLKSRRNPRLVPYALLDERTKKSNRDSLREAIRTMVGYGYDIDPPDQEAVHMM DDQSIETIRFFRVEQTYAVKTGKWYFEFESLTGGDMRVGWARPGCRPDVELGVDDQAFVF DGYRGRRMHVGSRYFGHPWKKGDVVGCMINMEDKSMIFTLNGELLITNKGSELCFADFET EDGFIPVCSLGMSQIGRMNLGKDANTFKYYTMCGLQEGFEPFAVNMNREITMWFSKRLPT FVNIPQDHMHVEVTRIDGTVDSPPCLKVTHKTFGTQNSNNDMVYCRLSMPVEFYSADNSG SDANENLIMEEQHHPPKEDGTMDYGSITTYYHSVRVFAGQDPASVWVGWVTPDYHYHSKS FGLSKTRTVTVTLGDERGRVHESVQRSNCYMVCGADAVGPSSSNRSNSDLEIGCLIDLAT GLVSFTANGKELPTTYQVEPNTKLFPSVFVRPTSPNLFQFEFVKIKDAMPLSSAIFKSEH RNPVPQCPPRLDVQTIVAVLWSRMPNTFLTVETARVSERHGWVVQCLEQLQIMAVHIPEE NRCLDILELSEHEDLRKFHYHTLKLYCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLS GMLREGFYNVLISIHLETAKEARLMMNNEFIIPVTDETRSIKLFPDESKRHSLPGVGLST SLKPRVNFSPVGIINTKRHQYLYSPQIPLVILKEKAISMLTEAVQGGGTHIRDPVGGSAE YQFVPILKLIGTLLIMGVLTSEEVRLILLLIDPNVFGEATEGEEGKADEVAEAGEKEEVS KNEEKAVEAGEEETKESKAPAKGLLEKSLPESVKRQMCELLHYFCDCELKHRIESIVSFS DSFVSKLQFNQKFRYNELMQALNMSAAVTAKKTKEFRSPPQEQINILLNFSAGEDCPCPE EIQDELNSFHEELRLHCGIPVEEEEEEQDTSIKGRLLALLYKIKGPPQKTEEEPTETEQA APTNLKELISQTITSWAQESHIQDPELVRVMFSLLRRQYDGIGELLRAMKKSYTISAASV QDAINLLASLGQIRSLLAVRMGKEEEKLMIDGLGDIMNNKVFYQHPNLMRVLGMHETVME VMVNVLGGDKSQEIAFPKMVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASEA MRGSTPLDVAASSVMDNNGLALALEEPDLEKVVTYLAGCGLQSCAILVAKGYPDLGWNPI EGERYLSFLRFAVFCNGESVEENANVVVKLLIRRPECFGPALRGEGGQGLLTAMKEAIKI SEDPALDLPKTSAGVTTASGEEEGEIIHMGNAIMSFYSALIDLLGRCAPEMHLINAGKGE ALRIRAILRSLVPTTDLVGVISIPLKMPVVNKDGTVTEPDMSASFCPDHKAPMVLFLDRV YGIEDQSFLLQMLEVGFLPDLRASASLDTEVLSTTETALAMNRYIGSALLPLLTRCAALF GNTEHYAQLIDSTLQTIYRLSKGRSLTKAQRDAIEECLLAICKHLRPSMMQQLLRRLVFD VPMLTEYCKIPLRLMTNHYEQNWKYYCLPSGMGSFGIASEEELLLTKKLFWGIFDSLSHK KYDAELFKMAKSCLCAIAGALPPDFVDASLGATLEKQASVDAQGNFDPKPTNTANISLPE KLEYIANKYAEHSHDKWSSEKVSAGWKNGDSVDEQAKTHPLLKPYKSLSEKERETYRWPV RESLKSMLAMGWNIERTKEGEVMFQQRESEKQRKISESQVNGFSPAPMDLHNVTLSRELQ GMVEVVAENYHNIWAKKKKTELVSKGGGTHPLLVPYDTLTAKEKYRDREKAQDLFKFLQI SGYAITRGLKEMEQDSSSMEKRFSFKFLKRLLKYIDSAQEFIAHLEAMATSGKTDKSPHD QEIKFFAKVLLPLTDQTFRNHCLYFLSTPSKSFSSCGCASNKEKEMVTSLFCKLAALVRH RISLFGSDSAMMVSCLDILTHSLDTRTVMKSGAELVKAGFKTFFENAAEDLEKLVEMLKL GKFMQSRAQMKSVSQSINYVTVALLPILTALFDHIRTYEFGVDLLLDDVQLSCYRILTCF YCLGTGKNVFVERHLPALGESLATLVGAIPVAFLEPHLNAHNPLSVFNTKTPRERAILSM PDTVEEMCPEMPSLDRLLKDVNDVSESGARYSDMPQVIEVILPMLCNYLSYWWEKGPESS PPGSQCCTMVTSEHLSIILGNILRILNNNLGIDDAPWMKRIAVYSQPIICKAGADLLRTH FLPTLDKLKKKTVKVVAEEELLKADSKGDNQEAELLILDEFAVLCRDLYAFYPMLIRYVD NNRSRWLKEPDADSTELFRMVAEIFILWCKSHNFKREEQNFVVQNEINNLGFLTGEGKAK MSKSGGDQERKHKRRRGEYYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKIRYSLK DTDDEVKEHLRQNLHLQDKSDDPAVQWQLDLYKDVVLKSDLPIDSEHTVVRVQSISAAVF HLEQVEQPLRNKKCVWQKLLSKQRKRAVVACFRMAPLYNLPRHRAINLFIPAYERLWIEA EEYSFEEKLVQDLAKTPMKIVEEEEEEVAEIQPDPLHQLILHFSHNALTERSYLEEDPLY IAYADMMAKSCAEDEEEEEEEGKEKTFEEKEMEKQKILYQQARLHARGAAEMVLQMISAS KGRLGPMVTCTLKLGISILNGGNVQVQQKMLVYLKEKRDAGFFKSLSGLMQSCSVLDLNA FERQNKAEGLGMVTEEGSSKYIFSQGSKVLQNDEFTKDLFRFLQLLCEGHNRDFQNFLRT QTGNTTTVNIIISTVDYLLRLQESISDFYWYYSGKDVIDDTGKINFSKALSVAKQIFNSL TEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDASQIELLKELMDLQKDMVV MLLSLLEGNVVNGTIGKQMVDTLVESSNNVEMILKFFDMFLKLKDLTTSDNFKEYDPEFK GIISKKEFQKSMESQKQYSQSEIDFLLSCAEADENDMFNYKEFVERFHEPAKDIGFNVVV LLTNLSEHMPHDSRLATFLDLAESVLSYFEPYLGRIEIMGSAKRIERVYFDISESSREQW EKPQVKESKRQFIFDVVNEGGESEKMEMFVNFCEDTIFEMQLASQISEPDEVEQPEEEED EDGHSILEELAAEEGGALESASAFSTACCAVKKKVAHVRQIFSIKNVRKQFKKIKKLTIK EIITGFFSFFWMLFTGFFKGIYSLIFGFFHVIWSSMFGGGLVEGAKNIKVTDILGNMPDP TQFGIHGDVIEGEKVEAIESSGNLDIAMAPAGDIAEVDMMLEMLTMPKKEGGKHLEPGLG DVSELSAETSTTDQKKKAAAKPVETPESEPEKADTENQEKEDKPKEEEAKEPVTEEKPKT RLSQAKEPAPAFMSNIFAALDIYLTKMLNYLARNFYNLRFLALFVCFAINFILLFYKVTG ETDEDTDDENQWGEEEEDQDTLFDMDEFVLQESTGYMLPTLRFLAIFHTVISLLCVVGYY CLKVPLVVFKREKEIARKLEFDGLYITEQPSDDDIKGQWDRLVINTPSFPNNYWDKFIKR KVINKYGDMYGAERIAELLGLDKSALDFDPTVETEEREASLVSWLSSIDTKYHIWKMGVV LTDNSFLYLIWYTTMSIFGHFNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGL LAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDELED PAGDPYELYRILFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGI GNDYFDRTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFP TGDCFRKQYEDQLG NT seq 14625 nt NT seq  +upstreamnt  +downstreamnt atgggtggggtcgggttgggagagggcagggtcaagttcccgctgtacacttggacgctg gtttgctgcgattacatctctgaggatgatgaggtggtgctccagagtgtggccaccatc cagaaggagcatcgcaagttctgcctggccgctgagggactaggaaaccgtatatgttac ctggaatccacgtcggaagctaagtatgttcctccggacctgtgtatttgtaactttgtg ttggagcagtccctgtcagtgcgggccctgcaggagatgttggctaacactgggcagagc agcgaagggagtgctgaccatgaaaaatgggcgggtcaggggggcggacatcggaccctg ctctatggtcatgccatcctcctacgccactccttcagtagtatgtacttgacctgtttg aagacatcaaggtctctgacagacaagctgtcgttcgatgtcggactacaagaagattca ataggagaatcctgttggtggaccatccaccctgcgtccaagcagaggtccgagggagag aaagtccgcatcggagatgacctgattcttgtcagtgtgtcaacagagagatacctgcac ctctctatctccaatggcaacatccaggtggatgcctccttcatgcaaactctgtggaac gtccagcctacctgctcctcaggcaacatggctgtagggtatttgattggtggacatgtg atgcgtctttgtcatgggcatgatgagagcttgaccatccctggagcagacaagaatgag gaagagcagaggatcgtcaactatgaggcgggtaagggagcgtctagggctcgctcactg tggagactggagcctctcaggatcagctggagcggtagccacatccggtggggccaggcc ttcaggctacgtcacctctctactggccattacctggccctgaccgaggaacgtggactg gtcctgcaggacagagaaaagtccgacaccacagccactgccttctgctttagggcctcc aaggaaaagggtgactcgggcccaaagagggacattgatggcatgggagtaccagagatc aagtatggagactctgtctgcttcatcatgcatctggcgacaggactatggctgtcttac ctggcacctgatgccaaatcttctcgcctaggacccctgaaaagacgggcctgtctacat tctgagggccacatggacgatgggctgaccctgcagcgctgccagcatgaagagtctcgg gctgcacgcatcatccgtaacaccacatttctcttcaccaacttcatcaaagccttggac agtactgcagagggcgagtctacagcggtggctgggtacgttgaagaggtgctgcagacg ctgaacgatctgatccagtacttcaaacagcccgactcggagttggagcacgaggagaaa cagtgtcttctccgttcgctcatcaaacgccaagacctcttcaaagaggaggggatgctg gccctcttgtccaaatgcattgaccgaatgaacctctacaacagtgctgcccactttgga gagatggctggggaggaggcgggcgctgcctggaaggacattctcaacctcctctatgag ctcctggcctcactgattcgtggtaacaggaacaactgcacccagttttcccgcaacttg gactggttgatcagcaaactggagagactggaatcttcatcaggaatcctggaagtcctc cactgtatcttggtagaaagcccagaggctctgaacatcatccagagagggcacattaaa tccatcatctctttgctctacaagcatggacgcaaccataagattctggatgtgttgtgt tccctctgtgtttgtaatggcgtggcagtgagagccaatcagaatctgatctgtgacaac cttcttcccaaaagggacctgctgcttcagactcgactggtcaatgatgttcagagtatg agaccaaacatcttcctgggcatggctgaaggttcagctcagtacaagaagtggtatttt gagctggtgatcgaccaggtggatcactttgtcactggagagccgacccacctgagggtg ggttgggccaacactaaaggctacgctccataccctggtggaggagagggatggggaggc aatggtgtcggggatgacctgtactcctacagctttgatggacttcacctgtggtcaggt cgaatcccgagggccgtggcctccattaaccagcacctgctgaactcagatgatgtggtc agctgctgtctggatttgggcgctcccagcatgtccttcaggatcaacgggcagcctgtc cagggcatgttcgaggacttcaatacagacggattcttcttccccgtcgtcagcttctct gcaggtgtcaaagtccgtttcctgttgggtgggcgccatggagatttcaagttcctgccg cccgctggttactctccatgctatgaggcgctgttgcccaaagagaagatgcatgtggag cctgtgaaggagtacaagagagaccacgagggggtccgtgatctgctgggaaccacccag ttcctctctcaggcttccttcatccccactcctgttgataccacccagattgttcttccc cctcacctggacaacgtccgggacaagctggcagaaaacattcatgaactgtgggggatg aacaagattgaactgggctggacctacggcaaggttcgtgatgacaacaagaggcagcac ccttgccttgtggattttgccaagctgcctgaaactgaaaggaactacaacctgcagatg tccagtgaaacacttaagaccctcttggcactgggatgccatgttgcccaggtcaatgtt cacgctgaggacgatctgaagaaaatcaaactacccaaagactacatgatgtctaatgga tataagcctgcgccactggacctctctgatgtgaaactgaatgcaggtcaggaggttcta gttgataaactggccgagaatgcacacaacgtgtgggccaaagacagaattaaacaagga tggacctatggcatccagcaggatttgaagagcagacgtaaccctcgcttggtgccatat gctttattggacgaacgtactaagaaatctaacagagacagtctgagagaggccatcagg accatggttggatatggatatgacatcgaccccccagaccaggaggccgtccatatgatg gatgatcagagcatcgagaccattcgcttcttccgcgtggagcagacatatgcagtgaaa acagggaagtggtactttgagtttgagtccctgactggaggtgatatgagggttggctgg gccagaccgggctgcagacctgacgtggaactgggagtggatgaccaagcctttgttttt gatggatacaggggtcgacgtatgcatgtaggcagccgctactttggacatccttggaaa aagggcgacgtggttggttgcatgatcaacatggaggacaaatccatgattttcaccctg aacggagagctcctgatcaccaacaagggctctgagctttgctttgctgactttgagaca gaggacggtttcatccctgtctgcagtctggggatgtctcagatcggccggatgaacctg ggcaaggatgccaatactttcaagtactacaccatgtgtggtctgcaggaaggctttgag ccctttgctgtcaacatgaacagagagatcaccatgtggttcagcaagcgcctccccacc tttgtcaacataccccaggaccacatgcatgttgaggtgacaaggatcgatggaacggtg gacagccctccctgcctcaaggtcacccacaagacgtttggcacccagaacagcaacaac gacatggtgtactgtagactgagcatgcctgtagagttctactctgcagacaacagtggg agtgatgcaaatgaaaatttaattatggaggaacagcaccatcctccaaaagaagatgga actatggactatggaagcatcacaacttactaccactcagttagagtgtttgctggacag gaccctgcctcggtgtgggtgggctgggtcacaccagactatcactaccacagcaagagc ttcggcctcagcaagacgcgaacagtcactgtcaccctgggagatgagaggggccgagtc catgagagtgtccagaggagtaactgctacatggtgtgtggagcagacgccgttggcccg tcttcctccaaccgctccaactctgacctggagatcggctgtttgattgaccttgccacc ggccttgtctccttcactgccaatggaaaagagctacccacaacgtatcaggtggaacca aataccaagctcttcccatctgtgtttgtacgccccaccagtccgaacctcttccagttt gaatttgtcaagatcaaggatgccatgccactctcatcagccatattcaagagcgagcac aggaacccggtgccacagtgcccgcctcgactggatgtgcagacaatcgtggccgtgctg tggagccgaatgccaaacaccttcctcactgtagagacagctcgggtcagcgagaggcat ggctgggtggtccagtgtctggagcagctgcagatcatggctgttcatatacctgaggag aacaggtgtttggatatcctggagttatcggagcatgaagacctgaggaagttccactac cacacgctgaagctgtactgcgccctctgtgccctgggaaacactcgtgtagctcacgcc ctctgcagccacttggaccaatcacagctcctctacaccatcgacaaccagtacctctct ggcatgctcagagagggcttctacaatgttctcatcagcatccatcttgagactgcaaag gaggctcgcctaatgatgaacaacgagttcatcatccctgtgacggatgagacgcgctcc atcaagctgttcccagacgagtccaagcggcactcactgcctggtgtgggactgagcact tccctcaaacctcgggtcaacttctcccctgtcggcatcatcaacaccaaacgccaccag tacctctacagccctcagatccctctggtcatcctgaaagagaaagccatcagcatgctc actgaggctgtgcagggcggaggcacgcacatccgagacccagtaggtggaagcgccgag taccagttcgtccccattctgaagctgatcggaacgctgttaattatgggcgtcctaacc agcgaggaggtaaggctgattctcctcctgattgaccccaacgtgttcggagaagccacg gagggtgaggaagggaaggcggatgaggtggccgaggcgggggagaaggaggaggtgagc aagaacgaagagaaggccgtggaggcgggagaagaggagaccaaggagagtaaagcgcca gctaaaggtctgctggagaagtcactgcccgagtctgtcaaacgccagatgtgtgagctg ctgcactacttctgtgactgtgagctgaagcaccgcatcgagtccatcgtctcgttctcc gacagctttgtgtccaagctgcaattcaaccagaagttccgttacaatgagctgatgcag gcgctcaacatgtctgccgccgtcactgccaagaagaccaaagagtttcgttcccccccg caggagcagatcaacatactgttgaatttcagtgcaggggaggactgcccctgtcccgag gagatccaggatgaactcaactccttccatgaagaattgcgactgcactgtggaattcca gttgaggaggaagaggaagagcaggacacttcgataaaaggccgtctccttgctctactc tacaagatcaagggtccacctcagaagacagaggaggagcccacagagaccgaacaggct gctcctaccaacctgaaagagctgatctcccagaccataaccagctgggcccaggagtct cacatccaggacccagagctggtcagggtgatgttcagcctgctgaggagacagtatgat ggcatcggggagctgctccgggccatgaagaaatcctacaccatcagtgctgcatctgtg caggatgctattaacctattggcatccctgggtcaaatcaggtctctgctggcagtgcgt atgggcaaagaggaggagaaactcatgattgatggactcggtgacatcatgaacaacaag gttttctaccaacatcccaacctgatgagagtgctgggcatgcacgagactgtcatggag gtcatggttaatgtgttgggaggagacaagtcacaggagattgccttccccaagatggtg gctagctgttgtcgtttcttgtgctacttctgtcgtattagccggcagaaccagaaagcc atgtttgaccacctgagctacctgctggagaacagcagcgttggactggcctctgaagct atgcggggctccactccgctggatgtcgcagcgtcctcagtgatggacaacaatggcctg gctctggccctggaggagcctgatctggagaaggtggtgacatacctggcaggttgtggt ctccagagctgtgccatactggttgctaagggttacccagaccttggctggaaccccatc gagggagagcgttacctgtccttcctgaggttcgcagtcttctgcaatggggagagtgtg gaggaaaatgccaatgtggtggtgaagctgctgatcagacgcccagaatgtttcggcccc gccctgaggggagagggaggccagggtctgctgactgctatgaaggaggccatcaagatc tctgaggatcctgccctggacctgccaaaaacctcggctggagtcactactgcgtctggt gaggaagaaggagagattatccacatgggcaacgccatcatgtccttctactcagctctc attgacctgctgggacgctgcgctccagagatgcatctgatcaatgcgggtaaaggtgag gcgctgcgtatccgagccatcctgcgctctctggttcctactacggacctggtgggtgtc atcagcatccccctcaagatgcctgtagttaataaagatggcacagtgacagagcccgac atgtcagccagtttctgtccggaccacaaggcccccatggtgctcttcctggaccgagtg tatggcatcgaggaccagagcttcctgctccagatgttggaggttggcttcttgcctgac ctccgagcctcagcgtctctcgatacggaggtgttaagcaccactgagacggcgttggcc atgaacaggtacatcggctcagccctgctgcccctgctgacccgctgtgccgctctcttc ggcaacacagagcactacgcacagttgatcgactccacgctgcagaccatctaccgactg tccaaaggccgctcgctcaccaaagcccagagggacgccattgaggagtgtctgctggct atctgcaagcatctgcgtccctccatgatgcagcagctgcttagacggctggtctttgac gttcccatgctcactgaatactgcaagatacctctacggctgatgaccaaccactatgag cagaactggaagtactattgcctgccatctggtatgggcagctttggcatagcctccgag gaggagcttctcctcactaagaagctattctggggaatctttgactccctttctcacaag aagtatgatgctgaacttttcaaaatggccaagtcatgcctgtgtgccatcgctggagcc ctccctcctgactttgtggatgccagtcttggcgcaacactggagaaacaggcttcagtg gatgcacagggtaactttgaccccaaaccaaccaacactgccaatatctcccttcctgaa aaacttgagtacattgccaacaaatatgcagagcattcccatgacaagtggtcctcagag aaggtgtcagctggctggaaaaatggagacagtgtggatgagcaggcgaaaacccatcca ctgctgaaaccttacaaatctctgagtgagaaggaacgagaaacataccgttggccagtg agggagtcgttgaagagcatgttagctatgggctggaacattgagaggaccaaggaggga gaagtcatgttccaacaacgagaaagtgaaaaacaacgaaagatctccgagtctcaggtt aatggattcagtcctgctccgatggacctgcataatgtcactttatctagagagttacag ggcatggtggaggtggttgcagaaaattaccacaacatctgggccaagaagaagaaaact gaacttgttagcaaaggaggagggacccacccactgctggtgccctatgataccctgaca gctaaagagaagtacagagacagagagaaggcccaggatctcttcaagtttctgcagatc agtggctatgccatcacaagaggtctgaaggaaatggagcaggactcatcatcgatggag aagcgtttctccttcaagttcctcaagaggctgctaaaatatattgactctgcccaggag tttattgctcaccttgaggccatggccaccagtgggaagacggacaaatcacctcatgac caggaaattaagttctttgccaaggtgttgcttcctctgacagatcaaacctttaggaac cactgtctctacttcctgtccacacccagcaagagctttagcagctgcggttgtgcctcc aacaaagagaaggagatggtcaccagcctgttctgtaagctggcagctcttgtcagacac aggatttctctctttgggagtgactcagcaatgatggtgagctgtctggacatcctcact cactcacttgacaccagaacggtgatgaaatctggcgccgagctggtcaaagccgggttt aagactttctttgagaatgcagcggaggacttggagaagctggtggagatgctgaaactg gggaagttcatgcagtcccgtgcccagatgaagagtgtcagtcagagcatcaattatgtg actgtggctctgctgcccatcctcactgccctgtttgaccacataaggacgtatgagttt ggagtggacctgctgttggatgacgtgcagctgtcctgctacagaatcctaacatgtttc tattgtctgggaacaggaaagaacgtctttgtggaaaggcatcttcctgcactgggggag agcctggccaccttggtgggagccatacctgtggcgttcctggagccccaccttaacgcc cacaacccactctctgtcttcaacaccaagacccctcgagagagagcaatcctcagtatg ccagacacagtggaggagatgtgtccagagatgccgagtcttgacagactcctgaaagac gtgaatgatgtctcagagtctggtgctcgctacagtgacatgccacaggtcattgaggtg atccttcccatgctgtgcaactatctgtcctactggtgggagaaaggtccggagagctca cctccaggttcccagtgttgcaccatggtgacctctgaacacctcagcatcatcctggga aatatcctcaggatcctcaacaacaacctgggcattgatgacgcaccctggatgaagagg attgcagtctactctcagccaatcatctgcaaggctggagcagatctgctgagaacccac ttcctgccaacactggacaaactaaagaagaagacagtgaaggttgtggctgaagaggag ctgctgaaggccgacagcaaaggtgacaaccaggaggcagagctgctcatcctggatgag tttgctgtgctctgcagggacctctacgctttctaccccatgcttatccgttatgtggat aacaacaggtcaaggtggttgaaggagcctgatgcagactccactgagctcttcaggatg gtggctgagatctttatcctctggtgcaagtcccataactttaagcgtgaggagcaaaac tttgtggttcagaatgagatcaacaatttgggcttcctgactggagaaggcaaggcaaag atgtccaagtcaggtggagaccaggagaggaaacacaagcgtcgccgtggtgaatactac tccatccagacctctctgattgtcgctgccttgaagaagatgctgcccattggtctcaac atgtgcaccccaggtgaccaggagctcatctctttggccaagatacgctacagtctgaaa gacacagatgatgaggtgaaggagcacttgcgtcagaatctccatctccaggacaagtcc gatgacccagcagtccagtggcagttggacctatacaaggatgtggtgctgaagagcgac ctacctatagactcggaacacacagtggtccgtgtccagagcatctctgctgcagttttc catctggagcaggtggagcagcctctgaggaataagaagtgtgtgtggcagaagctgctg tccaagcagcgtaagcgcgctgtcgtggcttgtttccgcatggctccactctacaatcta cccaggcatcgcgctatcaacctcttcatcccggcctatgagagactttggatagaggca gaggagtactcctttgaggagaagctagttcaggatctggcaaaaacccccatgaagatt gtggaggaggaggaagaggaggtggctgagatccagcccgaccctctccatcaactcatc ctccacttcagccacaacgctctgacagagagaagttacttggaggaagatcctttgtat attgcatatgcagacatgatggcaaagagctgtgcagaggatgaagaggaagaagaggaa gaagggaaagaaaagacatttgaggaaaaggagatggaaaagcagaagatcctgtatcag caggcaaggctgcacgcccgtggggctgctgagatggtgctacagatgatcagcgccagt aaaggtcgtctaggccccatggtgacctgcaccctcaaactgggaatttccatcctaaat ggaggcaatgtgcaagttcagcagaaaatgcttgtttacctgaaagagaaaagagatgca gggtttttcaagagtctctcaggcctgatgcagtcttgcagtgtcctggacttgaatgca tttgagaggcagaacaaagcagaaggtcttggcatggtgacagaggaaggttcaagtaaa tatattttctcccaaggctccaaggtgctacagaatgatgagtttactaaagacttgttc cggtttttgcaacttctgtgcgaggggcacaatagagatttccagaacttcctgagaacc caaactggaaacacaaccacagtcaacatcattatcagcactgttgactatctgctccgt cttcaggaatctatcagtgacttctactggtactactctggcaaagatgtcattgatgat acaggaaaaatcaacttctccaaagctttatctgtagccaagcagatattcaactcactg actgagtatattcagggcccatgtattgggaaccagcagagtctggctcacagcagactg tgggatgcagtagtgggcttcttgcatgtatttgccaacatgcagatgaagctatctcag gatgccagtcagattgagctgttgaaggagctgatggacttacagaaggacatggtggtc atgctgttgtctctgctagagggtaatgtggtgaatggaacaattggaaaacagatggtt gacacactggtggagtcttctaacaatgttgagatgatcctcaaattctttgatatgttc ctcaaactgaaggatctaacaacctctgacaacttcaaggagtacgaccccgagtttaaa ggcattatttcaaagaaggagttccagaagtccatggagagtcagaagcagtacagccag tctgagattgatttcctgctctcgtgtgcagaggcagatgagaacgatatgtttaattac aaggagtttgtggagcgattccatgagccagccaaagacatcggcttcaacgtggtagtc ctgctgaccaacctgtctgaacacatgccacacgactctcgactcgccaccttcttggat ttggcagagagcgtgctcagctactttgaaccttacctgggtcgtattgaaatcatgggc agtgcaaagcgcattgagagggtatactttgacatcagcgagtcgagccgtgaacaatgg gagaagccacaggtcaaagagtccaagcgtcagttcatctttgatgtggtcaatgagggc ggagagagtgagaagatggagatgtttgtgaatttctgtgaggacaccatctttgagatg cagcttgcttcacagatctctgagccggatgaggttgaacaacctgaggaggaggaagat gaggatggacacagcatcctggaggagctggctgcagaggaaggaggtgccctggagtct gcctcagccttctccactgcatgttgcgcagtgaagaagaaggttgcgcatgtccgccaa atattttctattaaaaacgtacgcaagcagttcaagaaaatcaagaaactgaccatcaag gagattatcacaggcttcttctccttcttctggatgctcttcactggcttctttaaggga atctacagtctcatctttggtttcttccacgtcatctggtcctccatgtttggtggtggc ctggtagagggtgccaagaacataaaggtgacggacatccttgggaacatgcctgaccca acccaatttggtatccatggagatgtgatagaaggagagaaagtggaggctatagagtca tcaggaaacttagatatagccatggcaccagcaggggacatagcagaggtggacatgatg ctggagatgctgacgatgcctaagaaggaaggagggaaacatctggagcctggcctgggt gacgtttctgagctgagtgcagagacgtccactactgatcaaaaaaagaaagctgctgcc aagcctgttgaaactcctgagagcgaaccagaaaaagcagacacagagaaccaggagaag gaggataagccaaaggaggaggaagctaaggaaccggtgacagaggagaagcccaagacc agattgagccaggctaaagagccggcgcctgccttcatgtccaatatctttgctgctctg gacatctacctgaccaagatgctgaactacctggctcgtaacttctacaacctgcgtttc ctggctctgtttgtgtgttttgccatcaacttcattctgctcttctacaaggtcactggt gaaactgatgaggacactgatgatgaaaaccaatggggtgaggaggaggaagatcaggac acactttttgacatggatgagtttgtgcttcaggagagcactggctacatgttaccaacg ctgcgcttcctggctatattccacactgtcatctcgctcctctgtgtggtcgggtactac tgtctgaaggttcctttggtggtgttcaagagagagaaggagattgccaggaaacttgaa tttgatggtctctacattactgagcagccgtctgatgatgacatcaagggccagtgggat cgactcgtcatcaacaccccttctttccccaacaactactgggacaagtttatcaagcgc aaggtgatcaacaaatatggtgacatgtatggagctgaacgcatcgctgagctcttaggc ctggataagagtgctctcgactttgaccccacagtggagactgaagagagggaagcctcc ttggtctcctggctgagctccattgatacaaagtaccacatctggaagatgggtgtggtt ttgactgacaactccttcctgtatctgatctggtacaccaccatgtccatctttggacac ttcaacaacttcttctttgctgctcacttgctggacatcgccatgggcttcaagaccctt cgcaccatcctgtcttctgtcactcacaacgggaagcagcttgtgctgactgtgggtctg ctggctgtggtcgtctatctctacactgttgtggccttcaacttcttcaggaagttctac aataagagcgaggatgaagacgagcctgacatgaagtgtgacgacatgatgacgtgctat ttgttccacatgtatgtcggtgtgagagctggaggaggtattggagatgagctggaggac ccagctggagacccttatgagctctaccgcatcctgtttgacatcaccttcttcttcttt gtcatcgtcatcctgctggccatcattcagggtttgatcattgatgcctttggtgagctg agagaccagcaggagcaggtgaaggaggacatggagaccaaatgcttcatctgtggcatc ggcaacgactactttgatcggacgcctcacgggtttgaaacccacaccttacaagagcac aacctcgccaactacctgttcttcttgatgtacctgattaacaaggacgagactgaacat acgggtcaggagtcatatgtgtggaagatgtaccaggagagatgctgggacttcttccct actggggactgcttccgtaagcaatatgaggaccagttgggttag

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