KEGG   Shigella flexneri 301 (serotype 2a): SF0045
Entry
SF0045            CDS       T00097                                 
Symbol
folA
Name
(RefSeq) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
sfl  Shigella flexneri 301 (serotype 2a)
Pathway
sfl00670  One carbon pool by folate
sfl00790  Folate biosynthesis
sfl01100  Metabolic pathways
sfl01240  Biosynthesis of cofactors
sfl04981  Folate transport and metabolism
Module
sfl_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:sfl00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    SF0045 (folA)
   00670 One carbon pool by folate
    SF0045 (folA)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    SF0045 (folA)
Enzymes [BR:sfl01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     SF0045 (folA)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 1024577
NCBI-ProteinID: NP_706004
UniProt: P0ABQ6 A0AB36P891
LinkDB
Position
49141..49620
AA seq 159 aa
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNI
ILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVE
GDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
NT seq 480 nt   +upstreamnt  +downstreamnt
atgatcagtctgattgcggcgttagcggtagatcgcgttatcggcatggaaaacgccatg
ccgtggaacctgcctgccgatctcgcctggtttaaacgcaacaccttaaataaacccgtg
attatgggccgccatacttgggaatcaatcggtcgtccgttgccaggacgcaaaaatatt
atcctcagcagtcaaccgggtacggacgatcgcgtaacgtgggtgaaatcggtggatgaa
gccattgcggcgtgtggtgacgtaccagaaatcatggtgattggcggcggtcgcgtttat
gagcagttcctgccaaaagcgcaaaaactgtatctgacgcatatcgacgcagaagtggaa
ggcgacacccatttcccggattacgagccggatgactgggaatcggtattcagcgaattc
cacgacgccgatgcgcagaactctcacagctattgctttgagattctggagcggcggtaa

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