Scleropages formosus (Asian bonytongue): 108919534 Help Entry 108919534         CDS       T04919                                  Symbol ryr3 Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism sfm  Scleropages formosus (Asian bonytongue) Pathway sfm04020   Calcium signaling pathway sfm04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:sfm00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     108919534 (ryr3)    04020 Calcium signaling pathway     108919534 (ryr3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:sfm04040]     108919534 (ryr3) Ion channels [BR:sfm04040]  Voltage-gated cation channels   Ryanodine receptor    108919534 (ryr3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 Ins145_P3_rec MIR SPRY RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_8 EF-hand_5 Motif Other DBs NCBI-GeneID:  108919534 NCBI-ProteinID:  XP_029114125 LinkDB All DBs Position 15:complement(21935281..22135310) Genome browser AA seq 4898 aa AA seqDB search MAEGDGEDEIQFLRTDDEVVLQCVASIQKENRKFCLAAEGLGNRLCYLEPTSEAKYVPPD LCICNFVLEQSLSVRALQEMLAKTGQNSEGPRDLDRWAAQGGGHRTLLYGHAILLRHSFS GMYLTCLKTSRSLTDKLSFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRIGDDLILVSV SSERYLHLSISNGSIQVDASFMQTLWNVHPTCSGSNVEEGYLLGGHVMRLFHGHDECLTI PGSDQSEEQQRIVNYEMGKAGTKARSLWRLEPLRISWSGSHIRWGQPFRLRHLTTGHYLA WTEDKGLVLQDREKSDTTTTAFCFRASKEKVESSPKRDIEGMGVAEIKYGDSICFVMHVA TGLWLSYQAPDVKSARLGPLKRRACLHSEGHMDDGLTLQRCQHEESRAARIIRNTTGLFN HFIRDLDSLSGKNRVTVTLPIEEVLQTLNDLITYFQLPDAELEHEEKQIKLRSLKNRQNL FKQEGMLTLVSSCIDRLSVYNSAAHFGECAGDEAGAAWKEILNLLYELLAALIQGNRNNC TQFSQNLDWLVSKLERLESSSGILEVLHCILIESPEALNIIQRGHIKSIISLLYKHGRNH KILDVLCSLCVCNGVAVRANQNLICDHLLPKRDLLLQTRLVNDVQSMRPNIFLGVSEGSA QYKKWYYELMIDQVDPFLTSEPSHLRVGWANTKGYAPYPGGGEGWGGNGVGDDLYSYGFD GLHLWSGRVPRAVASINQHLLTSDDVVSCCLDLGAPSISFRINGQPVQGMFENFNTDGLF FPVVSFSAGVKVRFLLGGRHGDFKFLPPSGYAPCYEALLPKEKMRVEPVKEYKRDQDGVR DLLGTTQFMSQASFIPTPVETSQIVMPPHLEKVRDKLAENIHELWAMNKIELGWSYGKVR DDNKRQHPCLVDFSKLPETEKNYNLQMSTETLKTLLALGCHVVQVNINAEDDLKKMKLPK NYMMSNGYKPSPLDLSDVKLTPGQEVLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKSKR NPRLVPYALLDERTKKSNRDSLREAIRTLIGYGYNIEPPDQESAGHASERLSIDKIRFFR VEKTYAVKTGKWYFEFEAVTGGDMRVGWARPGCRSDLELGMDDQAFVFDGYRGHRFHMGS RFFGRTWHAGDVVGCMINMEDKSMIFTLNGEILITNKGSELCFADFETEEGFIPVCSLGL SQIGRMNLGKDASTFKYYTMCGLQEGFEPFAVNMNREITMWFSKRLPTFVNVPKDHSHVE VTRIDGTVDSPPCLKVTHKTFGTQNSNVDMLYCRLSMPVEFHATFRSNPSVDINGVHEDE TQKPKHRLTGKALKHHEEGRRIDYSSITTYYHSVRVFAGQDPSSVWVGWVTPDYHYYSNN FNLSKNRTVTVTLGDERGRVHESVKRSNCYMVWGGDIACTSHSSTRSNVDLEIGCLIDLA TGLVSFSANGKELPTSYQVEPNTKLFPAVFVRPTSPSLFQFELTKIKNAMPLSSAIFKSE HKNPVPQCPPRLDVQTIISVLWSRMPNNFLKVETARVSERHGWVVQCLEPLQMLAVHIPE ENRCVDIMELSEQEDLRKFHYHTLRLYCALCALGNTRVAHALCSHLDQSQLLYTIDNQFL SGMLREGFYDVLISIHLETAKEARLMMNNEFIIPVTDETRSIRLFRDESKLHLPPGVGLS TSLKPRLSFVLPCFITTKREQHLYSPKIPLDTLKEKAISMLTEAVQSGGHHIRDPVGGSV EYQFVPILKLIGTLLIMGVLASEDVHKILLLIDPNVFGEPKEEQPAEAIEKEEVTSNEEK AVEAGEEEAKEPKQPIKGLLEKRLPESVKLQMCELLHYFCDCELKHRIEAIVSFSDSFVS KLQYNQKFRYNELMQALNMSAAVTAKKTKEFRSPPQEQINMLLNFSMGEDCPCPEDIQEE LYEFHNELRLHCGIPIEEEEEEQDTSIKGRLLALWYKIKGPPQKTEEKPKEKELPVPTNL KELISQTMVSWAQECHIQDPQLVRVMFSLLRRQYDSIGELLRAMRKSYTISAASVQDTIN LLASLGQIRSLLSVRMGKEEEQLMIDGLSDIMNNKVFYQHPNLMRVLGMHETVMQVMVNV LGGGKSQEIAFPKMVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASPSMRGST PLDVAASSVMDNNGLALALEEPDLDKVVTYLAGCGLQSCPILLAKGYPDIGWNPIEGERY LSFLRFAVFCNGESVEENSSVVVKLLIRRPECFGPALRGEGGNGLLAAMKEAIKISENPA LDLPGGAQRIRSDTSIEDEEEEEVVHMGNAIMSFYSALIDLLGRCAPEMHLINKGKGEAL RIRAILRSLVPTEDLVGIISIPLKMPVVNKDGTVAEPDMSANFCPDHKAPMVLFLDRVYG IEDQSFLLHLLEVGFLPDLRASASLDTEALSTTETALAMNRYICSAMLPLLTRCASHFVG TEHHATLIDSTLHTIYRLSKGRSLTKAQRDAIEECLLAICKYLRPSMLQQLLRRLVFDVP LLSEYCKMPLKLLTNHYEQSWKYYCLPTGGSSGYGTASEEELLLTKKLFWGIFDSLSQKK YDPELFKMAMPCLSAIAGALPPDYVDASITTTLEKQVSVDAQGNFDPKPISTTNISLPEK LEYVVNKYAEHCHDKWAAEKVTLGWKFGETMDEKAKTHPLLKAYKSLIEKEREVYRWPVK ESLKSMLAMGWNIERTKEGEAMFQQRESEKLRKISQSSQQGNGYSPSPVDMSNVLLSREL QGMVEVIAENYHNIWAKKKKAELGSRGGGTHPLLVPYDTLTAKEKARDREKAQELFRFLQ INGYAITRGLRDMEQDSSSMERRFAYKFLKKLLKYVDSAQEFIAHLEAMATSGKTDKSPH EQEIKFFAKVLLPLIDQYFKNHSLYFLSSPSKNLSSSGYASNKEKEMVTSLFCKLAALVR HRISLFGSDSATMVSCLHILAHTLDTRTVMKSGSELVKAGLRTFFENAAEDLEKTLENLK LGKFTHSRSQMKGVSQNINYTTVALLPILTALFQHITQHHFGVDLLLDDVQASCYRILTS LYSLGTGKNIYVERQLPALGECLATLAGAMPVAFLEPHLNIHNPCSVFNTKTPRERAILG MPDTVEEMCPEIPRLDALMLDVNDMAESGARYTEMPHVIEVVLPMLCNYLSYWWEKGPEN TPEGSGVACCTTVTSEQLSVILGNILKILNSNLGIDEAAWMKRIAVYAQPIISKARADLL KTHFLPTLEKLKKKTVKVVAEEELLKSDSKADTQEAELLILDEFAVLCRDLYAFYPMLIR YVDNNRSRWLKEPDVDSNELFRMVAEIFILWCKSHNFKREEQNFVVQNEINNLSFLTGDS KTKMSKSFLGKSGGQDQERKHKKRRGEFYSIQTSLIVAALKKMLPIGLNMCTPGDQELIS LAKARYALKDTDDEVKEHLRQNLHLQEKSEDPAVQWQLNLYKDVVVKTEEPPDPERTVDR VQNISAALFHLEQVEQPLRSKKCVWQKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFLM GYQKIWIETETYSFEESLVQDLAMCVQKSQKKVDEEEEEEAELRPDPLHQLILHFSHNAL TERSYLEEDSLYIAYADMMAKSCAENEEEEEGAEKEKTFEEKEMEKQKTLYQQARLHDRG AAEMVLQMISASKGRLGPMVTYTLKLGISILNGGNVIVQQKMLDYLKEKRDAGFFKSLSG LMQSCSVLDLNAFERQNKAEGLGMVTEEGSINVSERGSKVLQNDEFTKDLFRFLQLLCEG HNNDFQNFLRTQTGNTTTVNIIISTVDYLLRLQESISDFYWYYSGKDVMDEPGQRNFSKA LAVAKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDSSQIELLK ELLDLQKDMVVMMLSLLEGNVVNGTIGKQMVDTLVESSSNVEMILKFFDMFLKLKDLTTS DSFKEYDPDGKGVISKKEFQKSMENQKQYSQSEIEFLLSCAEADENDMFNYQEFVERFHE PAKDIGFNVAVLLTNLAEHMPHDSRLSTFLDLAESVLSYFEPYLGRIEIMGGAKRIERVY FEISESSRTQWEKPQVKESKRQFIFDVVNEGGESEKMELFVNFCEDTIFEMQLASQISEP DTVERPEDDEEDLHSLLEELEEDVEEHALESSSAFSIACASMKKNLSSFRQMLTFKSMRK QYKKFRKMSIKEMITGFFSFFWMIFTGIFRFIYSLIWGFFHILWTFMFGGGLVEGAKNMK VTDILGNMPDPTQFGIHGDVLEAEKMETSDSSSAVDLVQMVKGDKVEADLMTELLNIQPK KEGGKHGPEPGLGDVSEIVGSDAPSLASAVRQKKAQKEAAGKEVAEMDQKAEPEKADTED GEKKDKAKEEVSSELPVKEEKKVHKKRHGQKKEEPEAFMASFFSGLDIYQAKMLNYLARN FYNLRLLALFVAFAINFILLFYKVTGDDSDEEDSDPWNGDDEDEDEDGMEYFVLQESTGY MAPTLRFLAVLHTIISFLCVVGYYYLKVPLVVFKREKEIARKLEFDGLYITEQPSDDDIK GQWDRLVINTPSFPNNYWDKFVKRKVIKKYGDLYGAERIAELLGLDKSALDFNPTEEAVA KEASLVSWLSSIDTKYHIWKMGVVFTDNPFLYLVWYTTMSILGHYNNFFFAAHLLDIAMG FKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDM MTCYLFHMYVGVRAGGGIGDEIEDPAGDPYELYRILFDITFFFFVIVILLAIIQGLIIDA FGELRDQQEQVKEDMETKCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYIINKD ETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLG NT seq 14697 nt NT seq  +upstreamnt  +downstreamnt atggccgaaggagacggggaggacgagatccagttcttgagaactgatgatgaagtggtg ctgcagtgtgtcgccagcatccagaaggagaaccgcaagttctgcctggctgcagaggga ctcggcaatcggctgtgctacttggagcccacgtcggaagccaagtatgtcccaccagac ctgtgcatctgtaactttgtgctggagcagtcgctgtcagtgcgggccctacaggaaatg ctggctaaaacaggccagaacagtgaaggaccacgcgacctggaccgatgggcagcacaa ggcggggggcaccgcacccttctgtatggtcatgccatcctcctgcggcactccttcagc ggaatgtacctaacctgtttgaagacatctaggtccttgacagataagttgtcgtttgat gtcggacttcaagaagattcaacaggtgaggcctgttggtggactatccaccctgcctcg aagcagaggtcagagggtgaaaaggtgcgcatcggtgatgacctcatccttgtcagcgtg tcttcagaacgctacctgcacctgtccatctccaatggcagcatccaggtcgatgcctcc tttatgcagacactgtggaatgtccaccctacttgctctgggagcaacgttgaagaaggg tatttgctgggtggacatgtgatgcgtctgtttcatgggcatgacgagtgcctcaccatt ccagggtcagaccaaagtgaagaacaacagcgaattgtgaactatgagatgggcaaagca ggtactaaggccaggtcattatggaggctagagcctctccgtatcagctggagtgggagt catatccgctggggacagcctttccgcttgcgccacctcaccacgggccactacctggca tggaccgaagacaaggggctggtgttgcaggatagggaaaagtctgacacaaccaccact gccttctgcttcagagcctctaaggaaaaggtggagtccagtcccaaacgggatattgag ggtatgggggtggcggagattaagtatggcgactcgatctgcttcgtcatgcacgtggcc acagggctgtggctgtcctaccaggcacctgatgtaaaatctgctcggctgggccctctg aagagaagggcctgtctccactcggagggccacatggatgacgggctgacactgcagcgc tgccagcatgaggaatcacgggcagcgcgtatcatccgcaacaccaccgggctcttcaac cacttcatcagagaccttgacagtctgagtgggaagaaccgtgtgacggtcaccctgcca attgaggaggtcttgcagactctgaatgacctcatcacctacttccagctccctgatgct gagctggagcatgaggagaagcagatcaagctacgctcgctcaagaaccgccagaacctc ttcaaacaggaaggcatgctgaccctggtgtccagctgtatcgaccgcctgagtgtgtac aacagtgcagcccactttggggagtgcgctggagatgaggctggtgctgcctggaaggag atactcaaccttctgtacgagcttctggctgccctgatccaggggaaccgcaacaactgc acccagttctcccaaaacctggactggctggtcagcaagctggagagactggagtcgtcc tcaggaatccttgaggttctccactgcatcttaattgagagtccagaagccctgaatatc atccagagaggccacatcaagtccatcatctcactgttgtataaacacggccgcaaccac aagattctggacgtgctctgttccctctgtgtttgcaatggcgtggctgtgcgggccaac caaaacctgatctgtgatcacctgctccccaagagagacctgcttctccaaacacggctg gtcaatgatgtccagagcatgaggcccaatatcttcctgggtgtgagcgagggttcagcc cagtacaaaaagtggtactacgagctgatgattgaccaggtggaccccttcctgaccagt gagccttcccaccttcgcgtgggttgggccaacaccaaggggtatgccccttacccaggg ggtggagagggctgggggggtaacggtgttggggatgacctctactcatatggctttgat ggcctgcacctgtggtctgggcgtgtcccacgggcggtggcctccatcaaccaacacctg ctgacctcggatgatgtggtgagttgctgcctggacttaggtgctcccagcatctccttc cgcatcaatggacagcccgtgcagggcatgtttgagaacttcaacaccgatggcctcttc ttccccgttgtcagcttctctgccggagtcaaggtgcgttttctgttgggtggtcgccat ggcgacttcaaattcctgcccccttcgggctatgcgccatgctatgaggccctgctgccc aaggagaaaatgcgggtggagccggtgaaggagtacaagcgtgaccaggatggagtcagg gacctgctgggcactacccagttcatgtcccaggcctccttcatccctacacctgtggaa accagtcagattgttatgcctccacacctggagaaagtccgagacaaactagctgagaac attcatgagctctgggctatgaacaaaatcgagcttggctggtcgtatggcaaggtgcga gatgataacaagaggcagcacccttgcctggtggatttctccaagctacctgaaactgaa aagaattataacctgcagatgtctacagaaaccctaaagacgttgctggcactgggatgc catgttgtccaggtcaacatcaatgcagaagatgatctaaaaaaaatgaaacttcctaag aactacatgatgtcgaatggttataaaccctcaccactggatctttctgacgtgaaattg acacctggtcaggaagttctggttgataaactggctgagaacgctcacaacgtctgggcc aaggatagaatcaagcaaggatggacctatggcattcagcaggatttgaagagcaagcgc aacccacgactggtgccatatgctttattagatgagcgcactaagaagtcgaacagagac agcctccgtgaggctattcgcacactaattgggtatggatacaacattgaacctccagac caagagagcgctggccatgcaagtgagaggctgagcatcgacaagatccgtttcttccgt gtagagaaaacgtacgctgtgaaaacagggaaatggtactttgagtttgaagcagttaca ggaggagacatgcgtgtcggttgggctcgaccaggatgcagatccgacctggaactgggc atggacgaccaagcctttgtgtttgatgggtataggggtcaccgcttccacatgggcagc cgcttctttggccgtacctggcatgccggtgatgtggtgggctgcatgatcaacatggag gacaagtccatgattttcactttgaatggggagatccttatcaccaacaagggctccgaa ctctgcttcgctgactttgagacagaggaaggatttatcccagtgtgtagcttgggcctc tcacagattggccgcatgaaccttggaaaggatgccagcacattcaagtactacactatg tgtggtcttcaggagggctttgagccctttgctgttaacatgaatcgagaaatcaccatg tggttcagtaaacgtctaccaacctttgtcaatgtcccaaaagaccacagccatgttgag gtgaccagaattgatggaacagttgacagtccaccatgccttaaagtgactcataagacg tttggaacccagaacagcaacgttgacatgttgtactgccgtctaagcatgcctgtggag tttcatgcaaccttcaggagcaacccttcagttgacataaatggagtgcatgaggacgag acccagaagccaaaacacagacttaccggaaaggctctgaaacaccatgaagaaggaagg aggatagattacagcagcatcaccacgtactatcactcggtgagggtgtttgcaggtcag gacccctcctctgtgtgggtgggctgggtcaccccagactaccattactacagcaacaac ttcaacctcagcaaaaatcgaactgtcacggttacgctgggagatgaacggggacgagtg catgagagtgtcaagaggagcaactgctacatggtgtggggtggggacattgcttgcacc tcgcactcttctacccgcagcaatgtggacctggaaattggctgtctcattgacctggcc acaggtcttgtttctttctctgctaatggaaaggagttgcccacctcataccaggttgag cccaacacaaaactcttcccagcagtgtttgttcgacccactagtcccagcctcttccag tttgagctgacaaagatcaagaacgccatgccgctgtcatctgccatctttaagagtgag cacaagaacccggtgccgcagtgcccacctcggctggatgtgcagaccatcatctcagtg ctgtggagccgcatgccaaacaacttcttgaaggtggagacagctcgagttagcgagcgt catggctgggtggtgcagtgtctggaaccactgcagatgctagctgtgcacatccccgag gagaacaggtgtgtagacataatggaactttcagaacaggaggacctaaggaagttccac taccacaccttgaggctctactgtgctctctgcgccctgggcaacacccgtgtggctcat gccctctgcagccatctagatcagtcccaactgctgtacaccattgacaaccagttcttg tcaggcatgttgcgtgaggggttctatgatgtgctcatcagcatccacctggagacggct aaggaggcacgtctcatgatgaataatgagttcatcatcccagtgacggacgagacacgc agcatccggctcttccgagatgaatccaagttgcacttgcctccgggcgtgggattgagc acgtcactcaaaccacggctcagttttgtgctgccctgtttcatcactaccaagcgagag cagcacctctacagccccaaaatcccacttgacactctcaaggagaaggctatcagcatg ctgaccgaggctgtacagagtggggggcaccacatccgagacccagtgggcggcagtgtg gaataccagtttgtgcccatccttaaactcattggcacactccttattatgggtgtgctg gcaagcgaggatgtacacaagattctgctgctcattgaccctaatgtctttggtgagcct aaggaggaacagcctgcagaggccattgaaaaggaagaggtgaccagcaatgaggaaaag gcagtagaggcaggagaggaggaggctaaggagccaaagcagcctattaagggtctcctg gagaaacgtttgcccgagtcggtcaaattgcagatgtgtgaactcctacattatttctgt gactgtgagctgaaacatcgcatcgaggccatcgtgtccttctcggacagctttgtgtcc aaactgcagtacaaccagaagttccgctacaatgaactgatgcaggccctcaatatgtct gccgccgtcactgccaagaaaaccaaggagtttcgatcccctccccaggaacaaatcaac atgctgctgaactttagcatgggagaggactgcccctgccctgaagacatccaggaagag ctgtacgaattccacaatgagctgcgcctgcactgcggaatccccattgaggaggaggaa gaagagcaggacacctccatcaagggccgcctgcttgctctttggtacaagatcaagggg cccccacagaaaacggaggagaagcccaaggagaaagagcttcctgttcccacaaacctt aaggagctaatatctcagaccatggtgagctgggcgcaggagtgtcatattcaggaccct cagttggtgcgcgtcatgttcagcctgctacggcggcagtacgacagcatcggcgagctt ctgcgtgccatgcgaaagagctacacgatcagcgctgcctcggtgcaagacaccatcaac ctgctggcttcactgggccagatccgctcgctgctcagtgtccgcatgggcaaagaggaa gagcagctgatgattgatggtttgagtgacatcatgaacaacaaagtgttctaccagcat cccaacctgatgcgtgtcctgggtatgcatgagactgtgatgcaagtgatggtcaatgtt ctaggtggaggaaagtcccaggagattgcgttcccaaaaatggtggccagctgctgtcgc tttttgtgttatttctgccgcatcagcaggcagaatcagaaggccatgtttgaccatctg agctacctcttggaaaatagcagcgtaggactcgcctctccttccatgaggggctccact ccgctggacgtggcggcttcgtcagtgatggataacaatgggctggcactggcactggag gagcctgacctggacaaggtggtcacatacttggctggctgcgggctccagagctgcccc atactcctagcaaagggttaccccgacatcggctggaaccctatcgaaggagagcgctac ctgtccttcctccgctttgccgttttctgtaatggtgaaagtgtagaggagaactcaagc gtcgtggtgaagctgctgatccgacggcctgagtgttttggcccagcactccggggtgag ggaggcaatggcctcctggctgccatgaaggaggccatcaagatttctgagaacccagcg ctggatttgcctggtggtgcccagaggatcaggtctgatacctctattgaggatgaagag gaggaagaggtggttcacatgggtaatgccatcatgtccttctactctgccctcattgac ctactgggacggtgtgccccagagatgcatctcattaacaagggcaaaggggaggctttg cggattcgtgccattctgcgctcccttgtacccacagaagacctggtgggcatcatcagc atacccctcaaaatgcctgtggtgaataaagatggcactgtggcggagccagacatgtca gccaacttctgtccagaccacaaggcccccatggtactgttcctggaccgtgtctatggt atcgaggaccaaagcttcctgctgcacctgctggaggtgggcttcctgcccgacctgcgt gcctctgcctctctggacacggaggcgctgagcaccacagagacagccctggccatgaac agatacatttgctcagcaatgcttcccctgctgacccgctgcgcctcacactttgtgggc acagagcaccacgccacattaattgactcaacgctgcataccatctaccggctttccaag ggccgctccctcaccaaagcacagcgggatgccattgaggagtgcctactcgccatctgc aagtacttgcgcccttctatgctgcagcagctcctgcgccgccttgtcttcgacgtgccc ttactgtcagagtattgcaaaatgcctctgaagctcctgaccaatcactatgagcagagc tggaagtactactgcctgcccactggtggcagtagtggctacggcacagcatccgaggag gagcttctgcttaccaagaaactcttctggggcatctttgactctctctcgcagaagaaa tatgaccccgagctcttcaagatggccatgccctgcctgagtgccattgcaggggcactg cctccagactatgttgacgcctccatcacaaccaccctggaaaagcaggtctctgtggat gcacagggcaatttcgatcccaagcccatcagcaccacaaacatttcactacccgagaag ctcgagtatgttgtcaacaagtacgcagaacattgccatgacaaatgggcggcagaaaag gtgaccctgggctggaagtttggggagacaatggatgagaaggcaaagacacatcctctg ctgaaagcctacaaatccctcattgagaaggagagggaggtctaccgctggcctgtgaag gagtccttgaaaagcatgctcgccatgggttggaacattgagaggacgaaggagggggaa gccatgttccagcagcgtgagagtgagaagctgcgcaagatttcccagtcctcccagcag ggcaatggctacagccccagtccggtagacatgagcaatgtgcttctgtcacgggagtta cagggcatggtggaggtaatcgctgagaactaccacaatatttgggcaaagaagaagaaa gcagaacttggaagtcgaggaggcgggacacatcccttgctggtcccctacgatacactg actgccaaggagaaggcccgggaccgagagaaagcccaggagctgttccgtttcctgcag ataaacggctatgctatcacaagaggtctgagagacatggagcaggactcgtcctctatg gaaaggcgctttgcatacaaattcctgaagaagctactgaaatatgtagactctgcacag gaattcattgctcacctagaggccatggctaccagtgggaagactgacaagtctccacat gagcaagaaatcaagttctttgccaaggtgttgctcccactcatagaccagtacttcaag aaccatagcctctacttcctgtcctctcccagcaagaacctgagcagcagcggctatgcg tccaacaaagagaaggagatggttaccagtcttttctgtaaactggcagctcttgtcaga cacaggatttccctctttgggagcgattcggccaccatggtgagctgtctccatatcctg gctcacactcttgacaccaggacagtgatgaagtctggctcagagctagtgaaggcgggc ctgcgcaccttctttgagaatgctgccgaggacctggagaagacacttgagaacctgaag ctagggaagttcacgcattcgcgcagccagatgaagggggtttcacagaacatcaattat acgacagtggctctgctgcccatcctgactgccctgtttcagcacatcacccagcaccac tttggggtggatttgctactagacgatgttcaggcgtcctgctaccgtattctaaccagc ctgtactcactgggaacaggaaagaacatctacgttgagaggcagcttcctgccctgggg gagtgtctagccacattggcaggagcaatgcctgttgccttcctggagccccacctcaac attcacaacccctgctccgtgttcaacacaaagacaccccgcgagcgtgccatcctaggc atgccagacacagtggaggagatgtgtccggagattccccgactagatgccctgatgttg gacgtcaatgacatggctgaatctggggcacgctacacagagatgccacatgtcattgag gtggtcctgcctatgctgtgcaactacctgtcctactggtgggagaaggggccggagaac acacctgagggcagcggggtggcctgctgcaccactgtcacttccgagcagctcagcgtc attctagggaacatcctcaagatcctcaacagcaacctgggcatcgatgaggctgcttgg atgaagaggattgctgtctatgcccagcccatcatcagcaaggcacgggcagacctgctg aagacccacttcctgcccacattggagaagctgaagaagaagaccgtgaaggtcgtggcc gaggaggagctgttaaagtctgacagcaaggctgacacccaggaggctgagctgctcatc ctggacgagtttgctgtgctctgccgggacctctatgctttctaccccatgctgatacgc tacgtggacaacaacaggtccaggtggttgaaggagccggacgtggactcaaatgagctt ttccgaatggtggctgagatcttcattttgtggtgcaaatcacataacttcaaaagggaa gagcagaactttgtggtccagaatgaaatcaacaacttgtccttccttactggagacagc aagaccaagatgtccaagtcatttctgggaaagtcaggaggccaggaccaggagaggaag cacaagaagcgccgtggtgagttctactccatccagacttctctcatcgtcgcagccctg aagaagatgctgcccattggcctcaacatgtgtacccctggcgaccaggagctcatttcc ctggccaaggctcgctatgccctgaaagacacagatgatgaggtcaaagagcacttacgg cagaatctgcacctacaggagaagtcagaggaccctgctgtgcagtggcagctcaacctc tacaaggatgtggtggttaaaactgaggagccccctgaccctgagagaactgtggaccgt gtgcaaaacatctctgctgctctgttccacctggagcaggtagagcagcccctgcggtca aaaaagtgcgtttggcagaaactgctttcaaaacagcgcaaacgtgcagtggttgcttgt ttccgtatggccccactctacaacttacccaggcatcgctctattaacctcttcctcatg ggctatcagaaaatttggatagagacagagacgtattcatttgaggagagcctagttcag gacctggcaatgtgtgtgcagaagtcacagaagaaggtggatgaggaagaggaggaagaa gcagagctgcgtcctgatcctcttcatcagcttattctacatttcagtcacaatgctctc acagaacgaagttacctggaggaggactccttgtacattgcatatgctgacatgatggcg aagagctgtgcggaaaatgaggaggaggaagagggcgcagagaaagaaaagacctttgag gagaaggaaatggagaaacagaagacattgtaccagcaggccaggttgcatgaccgagga gcagctgagatggtcctgcaaatgatcagcgccagcaaaggccgactgggacccatggtg acctacacactgaagttgggcatctccattctcaacggtggcaatgttattgtccagcag aaaatgttggattacctgaaggagaaaagagatgctggctttttcaagagcttgtctgga ctaatgcagtcctgcagtgtcttggacttaaatgcatttgaaaggcagaacaaagcagaa ggtcttggaatggtgactgaagaaggttcaatcaacgtgagtgagcggggttccaaggtg ctgcaaaacgatgagttcacaaaagatctctttaggttcttgcagctgctctgtgaaggt cacaacaatgacttccagaacttcttgcgtacgcagacaggaaataccaccactgtgaac atcatcatcagcactgtggattacctgctccgactgcaggaatccatcagtgatttctac tggtactactctgggaaggatgtgatggacgaacctggccagcgtaacttctccaaagcc cttgctgtagccaagcagatctttaattcactgactgagtatatccagggtccctgtatt gggaaccagcagagtctggcccacagcaggttgtgggatgccgtggtgggcttcctccat gtatttgccaacatgcagatgaagctgtcacaggactcaagtcagattgagctgctgaag gagctgctggatttgcagaaggatatggttgtcatgatgctctccttgctggaaggaaat gtggtgaatggaacaattggtaagcaaatggtcgataccctggtagagtcctcaagcaac gtggagatgatcctcaagttttttgatatgtttctcaagctgaaggatttaaccacctca gacagcttcaaagaatatgaccctgatggaaaaggggtaatttccaagaaagagtttcag aagtccatggagaaccaaaagcaatactcacagtcagagattgagtttctcctttcatgt gcggaagctgacgagaatgacatgttcaactatcaagagtttgtggaacgcttccacgag cctgctaaggacataggcttcaatgtggctgtgctcctcaccaacttggcagaacacatg cctcatgactctcgtcttagcaccttcctagacctggctgagagtgtcctcagctacttt gagccatacctgggccgtattgagattatgggaggtgccaagaggattgagagggtttac tttgagattagtgaatctagcaggacccagtgggaaaaaccgcaggtgaaggagtccaag cgacagttcatcttcgatgtggtcaatgagggtggagagagtgaaaagatggagctcttt gttaacttctgtgaagacaccatttttgagatgcagctggcttcccagatctcagaacca gatacagtggagagaccagaggatgatgaggaagatctgcacagcctgcttgaagaactg gaagaggatgttgaagagcatgctctcgagtcatcctctgccttctctatcgcctgtgcc tccatgaagaagaacctctccagctttcgtcagatgctcacttttaagagcatgcgaaag caatacaagaagttcaggaagatgagcatcaaagagatgatcacaggtttcttttctttc ttctggatgatcttcactggcatttttcgtttcatatacagcctgatttggggctttttc cacattttatggaccttcatgtttggtggaggtctagtagagggggctaaaaacatgaaa gtaacagacatcttgggcaacatgcctgaccccacccagtttggcatccatggggatgtg cttgaagcagaaaaaatggagaccagtgactcatcttctgcagttgaccttgtgcagatg gttaaaggagacaaggtggaagctgatcttatgacagaattattaaacatccaacccaag aaagaaggaggcaaacatggtccagagcctggcttaggtgatgtctccgagattgttggg tccgacgccccctcactagcaagtgctgtacgccagaaaaaagctcagaaggaagctgca ggcaaagaggttgctgagatggatcagaaggcagagccagagaaagctgacacagaggat ggtgagaagaaagacaaagccaaagaggaggtatcatctgaactccctgtgaaagaagaa aagaaggtccacaagaaaagacatggccagaagaaggaggaacccgaggctttcatggcc agcttcttctctggtctggacatctaccaggccaagatgcttaactacctggccaggaat ttctacaatcttcgcttactggctctgtttgtcgcctttgctatcaatttcattctgcta ttctacaaggtgactggtgatgactctgatgaagaggactcagacccctggaatggtgat gatgaagatgaagatgaggatggtatggaatactttgtgctgcaggagagcacgggatat atggcgcctactctacgcttcctggctgtgctacacacaataatttctttcctctgcgtg gtgggatactattacctaaaggtgcctcttgtggtgtttaagcgtgaaaaggagatagcc aggaagctggagtttgatggcctgtacatcaccgagcagccctcagatgatgatatcaag ggccagtgggatcggctcgtcatcaacacaccatctttccctaataactactgggacaaa tttgtaaagcgcaaggtgatcaaaaagtacggtgacctgtatggcgcggagcggattgct gagctgctgggtctggacaagagcgccctggacttcaacccaacagaggaggcagtggcg aaggaggcatctctagtgtcgtggctgagctccattgacacaaaatatcacatctggaaa atgggcgtggtgttcacagacaatcctttcctgtacttggtctggtacactaccatgtcc attttgggacactacaacaacttcttctttgctgctcacttactggacattgccatgggc ttcaagactctgagaacaatcttgtcctctgtcactcacaacggtaaacagctggttttg actgtggggctgctggctgtggtagtgtacctctacactgtagtggccttcaacttcttt cgcaagttctataataagagcgaggatgaagatgagcccgacatgaagtgtgatgacatg atgacttgttacctgttccacatgtatgtgggcgtgagagccggtggtgggattggagat gaaattgaggacccagcaggcgacccttatgagctttaccgtatactctttgacatcacc ttcttcttctttgtcatcgtcatcctgctggctatcatccagggtttgatcattgatgcg tttggagaactgagagaccaacaggagcaagtgaaagaagacatggagaccaaatgcttc atctgtgggattggaaatgactactttgacacaacgccgcatggcttcgagacacatacc ttacaagagcacaacttggccaactacctgttcttcttgatgtacattatcaacaaagat gaaacggagcacacgggtcaggagtcatacgtatggaaaatgtaccaagagaggtgctgg gatttcttccctgcgggtgactgtttccgcaagcagtacgaggaccagctagggtag

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