KEGG   Sorex fumeus (smoky shrew): 130028691
Entry
130028691         CDS       T10594                                 
Symbol
PRKACA
Name
(RefSeq) cAMP-dependent protein kinase catalytic subunit alpha
  KO
K04345  protein kinase A [EC:2.7.11.11]
Organism
sfum  Sorex fumeus (smoky shrew)
Pathway
sfum01522  Endocrine resistance
sfum04010  MAPK signaling pathway
sfum04014  Ras signaling pathway
sfum04020  Calcium signaling pathway
sfum04024  cAMP signaling pathway
sfum04062  Chemokine signaling pathway
sfum04081  Hormone signaling
sfum04082  Neuroactive ligand signaling
sfum04114  Oocyte meiosis
sfum04140  Autophagy - animal
sfum04211  Longevity regulating pathway
sfum04213  Longevity regulating pathway - multiple species
sfum04261  Adrenergic signaling in cardiomyocytes
sfum04270  Vascular smooth muscle contraction
sfum04310  Wnt signaling pathway
sfum04340  Hedgehog signaling pathway
sfum04371  Apelin signaling pathway
sfum04530  Tight junction
sfum04540  Gap junction
sfum04611  Platelet activation
sfum04713  Circadian entrainment
sfum04714  Thermogenesis
sfum04720  Long-term potentiation
sfum04723  Retrograde endocannabinoid signaling
sfum04724  Glutamatergic synapse
sfum04725  Cholinergic synapse
sfum04726  Serotonergic synapse
sfum04727  GABAergic synapse
sfum04728  Dopaminergic synapse
sfum04740  Olfactory transduction
sfum04742  Taste transduction
sfum04750  Inflammatory mediator regulation of TRP channels
sfum04910  Insulin signaling pathway
sfum04911  Insulin secretion
sfum04912  GnRH signaling pathway
sfum04913  Ovarian steroidogenesis
sfum04914  Progesterone-mediated oocyte maturation
sfum04915  Estrogen signaling pathway
sfum04916  Melanogenesis
sfum04918  Thyroid hormone synthesis
sfum04919  Thyroid hormone signaling pathway
sfum04921  Oxytocin signaling pathway
sfum04922  Glucagon signaling pathway
sfum04923  Regulation of lipolysis in adipocytes
sfum04924  Renin secretion
sfum04925  Aldosterone synthesis and secretion
sfum04926  Relaxin signaling pathway
sfum04927  Cortisol synthesis and secretion
sfum04928  Parathyroid hormone synthesis, secretion and action
sfum04934  Cushing syndrome
sfum04935  Growth hormone synthesis, secretion and action
sfum04961  Endocrine and other factor-regulated calcium reabsorption
sfum04962  Vasopressin-regulated water reabsorption
sfum04970  Salivary secretion
sfum04971  Gastric acid secretion
sfum04976  Bile secretion
sfum05012  Parkinson disease
sfum05020  Prion disease
sfum05030  Cocaine addiction
sfum05031  Amphetamine addiction
sfum05032  Morphine addiction
sfum05034  Alcoholism
sfum05146  Amoebiasis
sfum05163  Human cytomegalovirus infection
sfum05165  Human papillomavirus infection
sfum05166  Human T-cell leukemia virus 1 infection
sfum05200  Pathways in cancer
sfum05203  Viral carcinogenesis
sfum05205  Proteoglycans in cancer
sfum05207  Chemical carcinogenesis - receptor activation
sfum05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:sfum00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    130028691 (PRKACA)
   04014 Ras signaling pathway
    130028691 (PRKACA)
   04310 Wnt signaling pathway
    130028691 (PRKACA)
   04340 Hedgehog signaling pathway
    130028691 (PRKACA)
   04371 Apelin signaling pathway
    130028691 (PRKACA)
   04020 Calcium signaling pathway
    130028691 (PRKACA)
   04024 cAMP signaling pathway
    130028691 (PRKACA)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    130028691 (PRKACA)
   04081 Hormone signaling
    130028691 (PRKACA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    130028691 (PRKACA)
  09143 Cell growth and death
   04114 Oocyte meiosis
    130028691 (PRKACA)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    130028691 (PRKACA)
   04540 Gap junction
    130028691 (PRKACA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    130028691 (PRKACA)
   04062 Chemokine signaling pathway
    130028691 (PRKACA)
  09152 Endocrine system
   04911 Insulin secretion
    130028691 (PRKACA)
   04910 Insulin signaling pathway
    130028691 (PRKACA)
   04922 Glucagon signaling pathway
    130028691 (PRKACA)
   04923 Regulation of lipolysis in adipocytes
    130028691 (PRKACA)
   04912 GnRH signaling pathway
    130028691 (PRKACA)
   04913 Ovarian steroidogenesis
    130028691 (PRKACA)
   04915 Estrogen signaling pathway
    130028691 (PRKACA)
   04914 Progesterone-mediated oocyte maturation
    130028691 (PRKACA)
   04921 Oxytocin signaling pathway
    130028691 (PRKACA)
   04926 Relaxin signaling pathway
    130028691 (PRKACA)
   04935 Growth hormone synthesis, secretion and action
    130028691 (PRKACA)
   04918 Thyroid hormone synthesis
    130028691 (PRKACA)
   04919 Thyroid hormone signaling pathway
    130028691 (PRKACA)
   04928 Parathyroid hormone synthesis, secretion and action
    130028691 (PRKACA)
   04916 Melanogenesis
    130028691 (PRKACA)
   04924 Renin secretion
    130028691 (PRKACA)
   04925 Aldosterone synthesis and secretion
    130028691 (PRKACA)
   04927 Cortisol synthesis and secretion
    130028691 (PRKACA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    130028691 (PRKACA)
   04270 Vascular smooth muscle contraction
    130028691 (PRKACA)
  09154 Digestive system
   04970 Salivary secretion
    130028691 (PRKACA)
   04971 Gastric acid secretion
    130028691 (PRKACA)
   04976 Bile secretion
    130028691 (PRKACA)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    130028691 (PRKACA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    130028691 (PRKACA)
  09156 Nervous system
   04724 Glutamatergic synapse
    130028691 (PRKACA)
   04727 GABAergic synapse
    130028691 (PRKACA)
   04725 Cholinergic synapse
    130028691 (PRKACA)
   04728 Dopaminergic synapse
    130028691 (PRKACA)
   04726 Serotonergic synapse
    130028691 (PRKACA)
   04720 Long-term potentiation
    130028691 (PRKACA)
   04723 Retrograde endocannabinoid signaling
    130028691 (PRKACA)
  09157 Sensory system
   04740 Olfactory transduction
    130028691 (PRKACA)
   04742 Taste transduction
    130028691 (PRKACA)
   04750 Inflammatory mediator regulation of TRP channels
    130028691 (PRKACA)
  09149 Aging
   04211 Longevity regulating pathway
    130028691 (PRKACA)
   04213 Longevity regulating pathway - multiple species
    130028691 (PRKACA)
  09159 Environmental adaptation
   04713 Circadian entrainment
    130028691 (PRKACA)
   04714 Thermogenesis
    130028691 (PRKACA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    130028691 (PRKACA)
   05205 Proteoglycans in cancer
    130028691 (PRKACA)
   05207 Chemical carcinogenesis - receptor activation
    130028691 (PRKACA)
   05203 Viral carcinogenesis
    130028691 (PRKACA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    130028691 (PRKACA)
   05163 Human cytomegalovirus infection
    130028691 (PRKACA)
   05165 Human papillomavirus infection
    130028691 (PRKACA)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    130028691 (PRKACA)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    130028691 (PRKACA)
   05020 Prion disease
    130028691 (PRKACA)
  09165 Substance dependence
   05030 Cocaine addiction
    130028691 (PRKACA)
   05031 Amphetamine addiction
    130028691 (PRKACA)
   05032 Morphine addiction
    130028691 (PRKACA)
   05034 Alcoholism
    130028691 (PRKACA)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    130028691 (PRKACA)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    130028691 (PRKACA)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    130028691 (PRKACA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:sfum01001]
    130028691 (PRKACA)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:sfum03019]
    130028691 (PRKACA)
   03036 Chromosome and associated proteins [BR:sfum03036]
    130028691 (PRKACA)
Enzymes [BR:sfum01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     130028691 (PRKACA)
Protein kinases [BR:sfum01001]
 Serine/threonine kinases: AGC group
  PKA family
   130028691 (PRKACA)
Messenger RNA biogenesis [BR:sfum03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     130028691 (PRKACA)
Chromosome and associated proteins [BR:sfum03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    130028691 (PRKACA)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_C
Other DBs
NCBI-GeneID: 130028691
NCBI-ProteinID: XP_055975491
LinkDB
Position
Unknown
AA seq 351 aa
MGNAAAAKKGSEQESVKEFLAKAKEDFIKKWENPSQNTAQLDHFERIKTLGTGSFGRVML
VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVTFPFLVKLEFCFKDNSNLYMV
MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY
IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF
ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLRNGVSDIKGHKWFAT
TDWIAIYQRKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF
NT seq 1056 nt   +upstreamnt  +downstreamnt
atgggcaacgccgccgccgccaagaagggcagcgagcaggagagcgtgaaagagttctta
gccaaagccaaagaagattttattaaaaaatgggaaaacccttctcagaacacagcccag
ttggaccactttgaacgcatcaagaccctcggcacgggctccttcgggcgggtgatgctg
gtaaagcacaaagagacggggaaccactacgccatgaagatcctggacaaacagaaggtg
gtgaagctgaagcagattgaacacacgctgaacgagaaacgcatcctgcaggccgtcacc
ttccctttcctcgtcaagctcgagttctgcttcaaggacaactcaaacctctacatggtg
atggaatacgtgcccggcggggaaatgttctcgcacctgcgacgcatcgggaggttcagc
gagccccacgcccgcttctacgcggcccagatcgtgctgaccttcgagtacctgcactcc
ctcgacctcatctaccgggacctgaagcccgagaacctgctcatcgatcagcagggctac
atccaggtcacggacttcggcttcgccaagcgcgtgaaaggccgcacctggactttgtgt
gggacccctgagtacctggcccccgagatcatcctcagcaaaggctacaacaaggcggtg
gattggtgggctctgggggtgctcatctacgagatggctgcgggctacccccctttcttc
gctgaccagcccatccagatctacgagaagatcgtctctggaaaggtccggttcccgtcc
cacttcagctccgacctgaaggacctgctgaggaacctgctgcaggtggacctgaccaag
cgcttcggcaacctccggaacggggtcagcgacatcaagggccacaagtggttcgccacc
accgactggatcgccatctaccagcgcaaggtggaggcccccttcataccaaagtgcaaa
gggcctggggacacgagtaacttcgacgactacgaggaggaggagatccgggtctccatc
aatgagaagtgtggcaaggagttctcggagttctag

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