KEGG   Shigella flexneri 2457T (serotype 2a): S2889
Entry
S2889             CDS       T00128                                 
Symbol
nrdE
Name
(GenBank) ribonucleoside-diphosphate reductase 2, alpha subunit
  KO
K00525  ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
Organism
sfx  Shigella flexneri 2457T (serotype 2a)
Pathway
sfx00230  Purine metabolism
sfx00240  Pyrimidine metabolism
sfx01100  Metabolic pathways
sfx01232  Nucleotide metabolism
Module
sfx_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
sfx_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:sfx00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    S2889 (nrdE)
   00240 Pyrimidine metabolism
    S2889 (nrdE)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:sfx03400]
    S2889 (nrdE)
Enzymes [BR:sfx01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1  ribonucleoside-diphosphate reductase
     S2889 (nrdE)
DNA repair and recombination proteins [BR:sfx03400]
 Prokaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    S2889 (nrdE)
SSDB
Motif
Pfam: Ribonuc_red_lgC RNR_N Ribonuc_red_lgN
Other DBs
NCBI-ProteinID: AAP18023
UniProt: A0A0H2V1A5
LinkDB
Position
2769917..2772022
AA seq 701 aa
MDYHALNAMLNLYDSAGRIQFDKDRQAVDAFIATHVRPNSVTFSSQQQRLNWLVNEGYYD
ESVLNRYSRDFVITLFAHAHTSGFRFQTFLGAWKFYTSYTLKTFDGKRYLEDFADRVTMV
ALTLAQGDETLALQLTDEMLSGRFQPATPTFLNCGKQQRGELVSCFLLRIEDNMESIGRA
VNSALQLSKRGGGVAFLLSNLREAGAPIKRIENQSSGVIPVMKMLEDAFSYANQLGARQG
AGAVYLHAHHPDILRFLDTKRENADEKIRIKTLSLGVVIPDITFHLAKENAQMALFSPYD
VERVYGKPFADIAISEHYDELVADERIRKKYLNARDFFQRLAEIQFESGYPYIMYEDTVN
RANPIAGRINMSNLCSEILQVNSASEYDENLDYARTGHDISCNLGSLNIAHTMDSPDFSR
TVETAVRGLTAVSDMSHIRSVPSIEAGNAASHAIGLGQMNLHGYLAREGIAYGSPEALDF
TNLYFYTITWHALRTSMLLARERGETFAGFKQSRYASGEYFSQYLQGNWQPKTAKVGELF
ARSCITLPTREMWAQLRDDVMRYGIYNQNLQAVPPTGSISYINHATSSIHPIVAKVEIRK
EGKTGRVYYPAPFMTNENLALYQDAYEIGAEKIIDTYAEATRHVDQGLSLTLFFPDTATT
RDINKAQIYAWRKGIKTLYYIRLRQMALEGTEIEGCVSCAL
NT seq 2106 nt   +upstreamnt  +downstreamnt
atggattaccacgcgctgaatgcgatgcttaatctttacgatagcgcaggtcgcattcag
ttcgataaagaccgccaggccgttgacgcctttattgcgacgcatgtgcgtccgaacagt
gtgaccttcagtagccagcagcagcgcctgaactggctggtcaacgaaggttactatgat
gaaagcgttcttaatcgctactctcgcgactttgtcattacgctgtttgcccacgcacac
accagcggttttcgtttccagacattcctcggggcatggaagttttacaccagctatacg
ttgaagacattcgacggtaaacgttatctggaagattttgccgatcgagtcacgatggtg
gcgctgacgctggcacaaggcgatgagacgctggcgttgcaactgaccgatgaaatgctg
tcaggacgctttcagccagccacgccaacattcctcaactgcggtaagcagcagcgcggc
gaactggtttcctgttttttgctgcgtattgaagacaatatggagtcgattggtcgggcg
gtaaattccgcactgcagctgtcgaaacgcggcggcggcgtagcatttttgctgtcgaat
ctgcgggaagcgggcgcgccaattaaacgtattgaaaatcaatcttctggcgtaattccg
gtgatgaaaatgttggaagacgcattttcctatgccaaccaactcggcgcgcgtcagggg
gcaggtgcagtctatttacatgctcatcatcccgatattctgcgttttctcgacacgaaa
cgggaaaatgccgacgaaaaaatccgcattaaaacactgtcgctgggcgtggtgatcccg
gatatcactttccatctggcaaaagagaatgcgcagatggcgctgttttcgccctatgac
gttgagcgagtttatggcaagccgtttgccgatatcgccattagcgaacactatgacgaa
ctggttgccgatgaacgcatccgcaaaaaatacctcaacgcccgtgatttcttccagcga
ctggcagaaatccagtttgagtccggctatccctacatcatgtatgaagacacagtaaac
cgtgctaaccctatcgccgggcgcataaatatgagtaatctctgctcagaaattttgcag
gttaacagcgcctcagagtatgacgagaatctcgactatgcccgcacaggccatgatatt
tcctgcaatttaggttcgttgaatattgcgcacaccatggattcccccgatttttcccgc
acggtagagactgccgtgcgcggtttaacggcggtgtcagatatgagtcatatccgcagc
gtgccgtccatcgaagccggaaatgccgcctcgcacgccatcggactggggcagatgaat
ttacatggttatctggcgagggaaggcatcgcttatggttcgccggaagccctggatttc
accaatctctatttctataccatcacctggcacgcactgcgtacctcgatgttgctggcg
cgcgaacgcggtgaaaccttcgccgggttcaaacagtcacgctatgccagtggtgaatat
ttcagccaatatctgcaaggtaactggcagccgaaaacggcgaaagttggcgaactgttt
gcccgcagctgtattacgttacctacccgtgagatgtgggcgcaactgcgcgacgacgtg
atgcgctacggcatatacaaccagaatctccaggcggtgccgccaaccgggtctatctct
tatatcaaccatgctacgtcgagtattcatccgattgtggcgaaagtagagatacgcaaa
gagggcaaaacaggacgcgtttactaccctgccccgtttatgactaacgaaaatctggcg
ctgtatcaggacgcttacgaaattggcgcagaaaagatcatcgacacctacgcggaagcg
actcgccatgtcgatcaggggctgtcgctgacgctgtttttccccgataccgccaccact
cgcgatatcaacaaagcgcagatttacgcctggcgcaaaggtatcaaaacgctctattac
atccgcctgcgtcagatggcgctggaaggcactgaaattgaaggctgcgtctcctgtgca
ctttaa

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