KEGG   Streptomyces goshikiensis: PET44_28360
Entry
PET44_28360       CDS       T09307                                 
Name
(GenBank) SDR family NAD(P)-dependent oxidoreductase
  KO
K24528  protomycinolide IV synthase 1
Organism
sgk  Streptomyces goshikiensis
Pathway
sgk00522  Biosynthesis of 12-, 14- and 16-membered macrolides
sgk01100  Metabolic pathways
sgk01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:sgk00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00522 Biosynthesis of 12-, 14- and 16-membered macrolides
    PET44_28360
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins [BR:sgk01008]
    PET44_28360
Polyketide biosynthesis proteins [BR:sgk01008]
 Polyketide synthase (PKS)
  Modular type I PKS
   cis-AT PKS
    Protomycinolide IV synthase
     PET44_28360
SSDB
Motif
Pfam: ketoacyl-synt Acyl_transf_1 Ketoacyl-synt_C KR KAsynt_C_assoc PP-binding SpnB_Rossmann PKS_DH_N PS-DH Thiolase_N adh_short Epimerase GDP_Man_Dehyd Polysacc_synt_2 CurL-like_PKS_C ACP_syn_III Sacchrp_dh_NADP NmrA RmlD_sub_bind DUF2073 NAD_binding_4
Other DBs
NCBI-ProteinID: WBY23215
LinkDB
Position
6427353..6440504
AA seq 4383 aa
MAPKNGAQRSSDIAVVGMSCRLPGAPGIDEFWELLTSGGSAIERRADGTWRGSLEGAADF
DAAFFDMSPRQAAAADPQQRLMLELGWTALEDAGIVPGSLAGTDTGVFVGIAADDYAALL
HRSETPVSGHTATGLSRGMAANRLSYLLGLRGPSLAVDSAQSSSLVAVHLACESLRRGES
DLAIVGGVSLILAENSTAGMELMGALSPDGRCYTFDARANGYVRGEGGACVVLKPLDRAL
ADGDRVHCVIRGSAVNNDGGGSTLTTPHREAQEAVLRAAYERSGVGPDQVSYVELHGTGT
PAGDPIEAAALGAVLGTARGRSTPLSVGSAKTNVGHLEAAAGLVGFVKAALCVREGVVPP
SLNHATPNPAIPMDRLNLRVPTRLGTWPQPDEQATGRLRLAGVSSFGMGGTNAHVVVEEA
PVPEEGEFVGDAPLAVVPVVVSGRSAGVVAELASRMGGVAGSGRLVDVGWSSVVSRSVFE
HRSVVLAENATELNTGLDALAAGVVSPGVVSGVVSGEGGRSVFVFPGAGAKWSGMAARLW
AESVVFAESMARCEAAFEGLVDWRLADVLCDEAALEREDVAQPASFAVMVSLAELWRSLG
VVPDAVVGHSQGEIAAAVVAGGLSLEDGARAVVFRSRVAEEVLSGGGIASVRLSRAEVEE
RLAGGGGGLSVAVVNAPSSTVVAGELGELERFVAACEAEGVRARRLEFGYASHSVFVEPA
RGRLLEALADVRPVSGEIPFYSTVEAAVIDTASLDAGYWFGNLRRPVRFQETVEQLLADG
FRVFVECGAHPVLTAAVQETAESVGRQVCAVGSLRREEGGLRRFLTSVAEAFVQGVDVTW
PALFDGTGARTVDLPTYPFQRQHYWAPDGSASAALTLDSRPDETAAVPSDTTDLAGRLRR
EVVSLTAIEQVERLLDQVRDGVVTVLGLDAHAEVRAEATFKELGVESLTGVELKNHLRVR
TGLHVPTSLIYDCPTPLAAAHYLRDKLLGQSREQAVIHADNPVDEPIAIVGMGCRLPGGV
SSPEGLWDLVASGVDAVSPFPTDRGWDVAGLFDPEPGVPGRTYVREGGFLHGAGEFDAGF
FGISPREALAMDPQQRLLLETSWEALERAGIDPHSLRGSRTGVYAGVMAQEYGPRLHESA
DGYEGYLLTGSSSSVASGRISYVLGLEGPALTVDTACSSSLVALHLAVRALRSGECDLAL
AGGVTVMAEPGMFVEFSRQRGLAADGRCKAFSDSADGTGWAEGAGVLLVERLSDAVRHGH
RVLAVVRGSAVNQDGASNGLTAPSGRAQSRLIRRALADARLGVGDVDVVEAHGTGTRLGD
PIEAQALLATYGQRDAGRPLWLGSLKSNVGHTQAAAGVAGVIKMVMAMRHGVLPKTLHVD
EPTAEVDWSAGTVALLTEQVPWPRSERVRRAGVSSFGVSGTNAHVVLEEAPVPEEGQFVG
DAPLAVVPVVVSGRSAGVVAELAGQMGGVAGSGRLVDVGLSSVVSRSVFEHRSVVLAEDS
VELNTGLDAVAAGVPSSGVVSGVVSVEGGRSVFVFPGQGTQWVGMAVRLWAESGVFAESM
ARCEAAFEGLVDWRLADVLGDEVALERVEVVQPVAFAVMVSLAELWRSLGVVPDAVVGHS
QGEIAAAVVAGGLSLEDGARVVVLRAGLIGRELAGHGGMASVALPVGVVEERLARWAGRL
GVAVVNGPSATVVAGDTDAVAEFVTTCETEGVRARRLPVDYASHSAHVETLAAELEEILS
DVRPVSGEIPFYSTVEAGLVDTASLDAGYWFGNLRRPVRFQETVERLLADGFPVFVEASA
HPVLTAAVQETAESMGRQVCAVGSLRREEGGLGRFLTSVAEAFVQGVEVSWPALFEGTGA
RTIDLPTYPFQHQRYWLESRPSAAVVPSGTQDGLSYEVTWKSLSLPESVRLDGRWLLVVP
EHLDADGTRVAHDIQHALTTHGATVSHLTVDVTATDRTDLSARLTTTAAEEQEPLGGILS
LLGWAEGAQVDRPTVPIAIATSLALVQAVGDAGFGVPVWAVTRGAVSVVPGEVPETAGAQ
LWALGRVAALELPDRWGGLIDLPANADARTAGLAVRALAAGIADGEDQLAVRPSGAYGRR
VVQAGHRKPKGAKPEWRPRGTVLVTGGMGAIGTRVARWLARNGAEHLVLTGRRGAGTPGA
DELAGELRASGVQVTLAACDVSDRAALAALIDAHPPTAVFHTAGVLNDGTVDTLTPGRLD
GVLGPKATAAVHLHELTAHLDLDAFVLFASVTGVWGNGGQAAYAMANAALDALAEQRRAG
GLAATSISWGLWGGGGMAEGNGEVSLNRRGIRALEPATGIEALQRTLDQDATCRTVVDVD
WSEFAPRTAALRRGRLFADLPEARRALGSEGAAQEGAGAAESAATFAERIASLPEPEQRR
ILVELVRAEAAAVLRHDTTELLAPRRSFKDAGFDSLTALELRNRLSTASGVVLPVTVVFD
HPNPGALADFLYGEALGLSAQHVAGSDQADTARPAIAPEEPIAIVGMACRYPGEAHSPEE
LWKLLMDERDVIGPMPTDRGWDVAGLFDPEPGVPGRTYVREGGFLYEAGEFDAGFFGISP
REALAMDPQQRLLLETSWEALERAGIDPNSLRGSRTGVYAGMFHQEYAARLHEAPAEFEG
HLLTGTSGSVASGRISYVLGLEGPAVTVDTACSSSLVALHLAVRALRSGECDLALACGVT
VMAEPGVFVEFSRQRGLASDGRCKAFAAAADGTGWAEGAGVLLVERLSDAVRHGHRVLAV
VRGSAANQDGASNGLTAPNGPSQQRVIRQALADARLGVGDVDVVEAHGTGTRLGDPIEAQ
ALLATYGQRDAGRPLRLGSLKSNVGHTQAAAGVAGVIKMVMAMRHGVLPKTLHVDEPSAE
VDWSAGAVSLLTEQVPWPRGERVRRAGVSAFGVSGTNAHVVLEEAPDVRESVEPSGEGLL
PVVPVVVSGRSAGVVAELASRMGEVAGSGRLVDVGWSSVVSRSVFEHRSVVLAENATELN
TGLDALAAGVVSPGVVSGVVSVEGARSVFVFPGAGAKWSGMAARLWAESVVFAESMARCE
AAFEGLVDWRLSDVIAQVPGAVSLEREDVAQPASFAVMVSLAELWRSLGVVPDAVVGHSQ
GEIAAAVVAGGLSLEDGARAVVFRSRVAEEVLSGGGIASVRLSRAEVEERLAGGGGGLSV
AVVNAPSSTVVAGELGELERFVAACEAEGVRARRLEFGYASHSVFVEPARGRLLEALADV
RPVSGEIPFYSTVEAAVIDTASLDAGYWFGNLRRPVRFQETVEQLLADGFRVFVECGAHP
VLTAAVQETAESVGRQVCAVGSLRREEGGLRRFLTSVAEAFVQGVEVSWPALFDGTGART
VDLPTYPFQRQHYWAQASPAGSGSSAAARFGMTWEEHPLLSGALPLAESGELLLVGRISP
ASHSWIADHTVAGTALLPGTAFVGMALHAAAVVGCAGVEELSIEAPLPVHGGIRLQVVID
EPDSSDRRRVSVFARPEAEDGHTGRWTRHATGVLTPAAAPDPGRPQWSREAWPPSGSVRA
EGAELYDRFSALGYEYGEVFAGVEAVWLREGEVFAEVRLPAGAAPDAERFGVHPGLLDAA
LQPWLLGDFLSRPDDGSVLLPFAWRGITLYATGADALRVRLGPAGEGAMSLEAVDLAGAP
VLSMDALVLRPLAQDRLVELVGGTTSAPLYRVDWQRSPIANTAPSATGLFGSFPSGATRR
WVVVGQGGAAARYATADPGTGCVGVFPDLDALRTALDSGAERPDIVLADFGARPGTAAPH
GTALADGVRDTARRGLALVQGWLSDERFAAARLAVLTEHAVATEADERQVDLAGSALWGL
MRSAQTEHPDRFVLVEHDGQDASYQALPAALDSGIPQLALRSGKVRTPGLAVLPTPGDGL
TATGTGFDPEGTVLVTGATGTLGSLLARHLVTAHGVRHLLLLSRSGRDAGRAAELERELT
GLGAEFQLLSCDATDRVALQEALATVPAAHPLTAVIHTAGVLDDGVVEALTPERLDRVLR
PKADAALNLHELTAGMPLKAFVLYSGSVGLLGGAGQANYAAANAFLDGLAQYRHAQGLPA
VSLAWGLWSAASTFTGHLGEVDLRRMERSGIAPLTNEQGLELLDRALGAAAGADAPQICA
MRLDTAALRRQAAEHGPASVPLLLRTLAAPAVRRGAARTGRGARAASAVTDVPSRAQDLR
ERLAGLDAAGRRDELLAVAQAQLADVLGFTDKTAVDPVRSFREIGLDSLTAVELRNRLDA
VTGLRLPSALVFDHPNLDALAGHLAELLMAEGKDDAGAAALSGIDALDRAVRGMAADDTR
RDAVRRRLTELLAVVGHAPRDGDRSTRTAAGTGSHGVQAGPDLLGQLDSASDDDLFAFIE
DQL
NT seq 13152 nt   +upstreamnt  +downstreamnt
atggcccccaagaatggtgcgcagcgttcgagcgacatagccgtcgtcggcatgtcctgc
cgccttccgggggcgcctggcatcgatgagttctgggaactgctgacctccggaggcagc
gcgatcgagcgtcgcgccgacggcacctggcgaggctccctggagggggccgccgacttc
gacgccgccttcttcgacatgtccccccgccaggccgccgccgcagatccgcagcagcgg
ctcatgctggaactcggctggaccgccctggaggacgccgggatcgtcccgggcagcctc
gccggcacggacaccggcgtcttcgtgggtatcgccgccgacgactacgcggcactcctg
caccggtccgagacccccgtcagcggccacaccgcgaccggcctgagccggggtatggcc
gccaaccgcctctcctacctcctgggcctgcgcggtcccagcctcgcggtggacagcgcg
cagtcctcctcgctggtcgcggtccacctggcctgcgagagcctgcgccgcggcgagtcc
gacctcgcgatcgtcggcggcgtcagcctgatcctcgccgagaacagcacggcaggcatg
gagctcatgggcgcgctctcgccggacggccgctgctacaccttcgacgctcgcgccaac
ggctacgtacggggtgagggcggagcctgcgtcgtcctcaagcctctggaccgggcactg
gccgacggggaccgcgtccactgtgtcatccgaggcagcgcagtcaacaacgacggcggc
ggctccaccctgaccacaccccaccgcgaggcccaggaagccgtgctgcgcgcggcgtac
gaacggtccggggtcggcccggaccaggtgtcctacgtcgaactgcacggcacgggaacg
cctgccggcgaccccatcgaggcggcggctctcggcgcggtgctcggcacggcccggggc
cggagcacaccgctgtccgtggggtcggccaagacgaacgtcggccacctggaagcggct
gcgggtctcgtgggattcgtgaaggccgccctgtgcgtccgcgagggcgtggtaccgccg
agcctgaaccacgcgacgcccaaccccgccatccccatggaccggctcaacctgcgcgta
cccactcgactgggcacctggccgcagccggacgagcaggcaaccggccggctgcgactg
gccggcgtctcgtccttcggcatgggtgggacgaatgcgcatgtggtggtggaggaggcg
cctgttccggaggagggggagttcgtcggggatgccccgttggctgtggtgccggtggtg
gtgtcgggtcgttcggcgggtgtggtggctgagctggcgtcccgtatggggggtgtggct
gggtctggtcggttggtggatgtggggtggtcgtcggtggtgtcgcggtcggtgttcgag
caccggtccgtggtcctggcggagaacgcaacggagttgaacaccggtctggacgccctg
gccgccggtgtggtgtcgcctggtgtggtgtcgggtgtggtgtcgggggagggtggccgg
tcggtgttcgtgttcccgggtgcgggggcgaagtggtcggggatggcggcgcggctgtgg
gctgagtcggttgtgttcgcggagtcgatggcgcggtgtgaggcggcgttcgagggcttg
gtggactggcgtctggcagatgtgctgtgcgatgaggctgcgttggagcgtgaggatgtg
gcgcagccggcctcgtttgcggtgatggtgtcgttggcggagttgtggcggtcgttgggt
gtggtgccggatgcggtggtggggcattcgcagggggagattgctgcggcggtggtggcg
ggtggtctgtcgttggaggacggggcgcgggcggtggtgttccggtcgcgggtggcggag
gaggttttgtcgggtggggggattgcttcggtgcgtctttcgcgggccgaggtggaggag
cggttggcgggtgggggtggtgggctgagcgtggcggtggtgaatgcgccgtcgtcgacg
gtggtggctggtgagctgggagagttggagcggttcgttgccgcgtgtgaggcggagggg
gtgcgtgcgcgtcggctggagttcgggtatgcgtcgcattcggtgttcgtggagccggcg
cgtgggcggttgctggaggcgctggccgacgtccgtccggtgagcggcgagatcccgttc
tactcgacggtggaagccgcggtgatcgacacggcgtcgttggacgcggggtactggttc
gggaatctgcgtcggccggtgcggttccaggagacggtcgagcagctgctcgcggacggt
ttccgggtgttcgtggagtgtggtgcgcatccggtgctgacggctgcggtgcaggagacg
gcggagtccgtgggccggcaggtgtgtgcggtcggttcgctgcgtcgtgaggaggggggt
ctgcgtcgtttcctgacctcggtggcggaggcgttcgtccagggcgtggacgtcacctgg
cccgccctcttcgacggcaccggcgcccggaccgtcgacctgcccacctaccccttccaa
cgccagcactactgggcacccgatggctccgcatcggcagcgctcacgctggacagccga
ccggacgaaaccgccgcagttccatcggacacgacggatctcgctggacgactccgccgg
gaagtcgtgtcgttgaccgccatcgagcaggtcgagcggttgctcgaccaggtacgcgac
ggtgtcgtcaccgtcctcggactggacgcccacgccgaagtgcgcgcggaggcgacgttc
aaggaactgggcgtcgaatcgctgaccggtgtcgagctgaagaaccacctccgtgtccgg
accggactgcacgtcccgacctcgctgatctacgactgcccgactcccctcgccgccgct
cactacctccgcgacaagctcttgggccaatctcgggaacaggctgtcatccacgccgac
aaccctgtcgacgagccgatcgcgatcgtggggatggggtgccggctcccgggtggggtg
tcgtcgccggaggggttgtgggatctggtggcgtcgggggtggacgcggtttccccgttc
cctaccgatcggggttgggatgtggcgggtctgtttgatccggagcctggtgtgcctggg
cgtacgtacgtgcgtgagggtgggttcctgcatggggcgggggagttcgacgcggggttc
ttcggtatttcgccgcgtgaggcgttggcgatggatccgcagcagcggttgttgctggag
acgtcgtgggaggcgttggagcgggcgggtattgatccgcattcgctgcgcggctcacgg
accggcgtctacgccggagtgatggcccaggagtacggcccccgactccacgaaagcgct
gacggatacgagggctatctgctgaccggatcctccagcagtgtcgcttcgggtcgtatc
tcgtatgtgctgggtctggaggggccggcgctgacggtggacacggcgtgttcgtcgtcg
ttggtcgcgctgcatctggcggtgcgggcgctgcgcagcggtgaatgtgacctggctctt
gcgggtggggtgacggtcatggccgaaccgggcatgttcgtggagttctcgcggcagcgg
ggtctggccgccgatgggcggtgcaaggcgttctcggactcggccgacggcacgggctgg
gccgagggtgcgggcgtgttgctcgtcgagcggttgtcggatgcggtgcgtcatggacat
cgggtgctggcggtggtgcgtggctcggcggtgaatcaggacggtgcgagcaacggactg
acggcgcccagtgggcgggcccagtcgcgtttgattcgccgggcgttggcggatgcgcgg
ttgggtgtgggtgatgtggatgtggtggaggcgcatgggacggggacgcgtctgggtgat
ccgatcgaggcgcaggcgttgctggcgacgtatgggcagcgggacgcggggcgtcctttg
tggcttggttcgctgaagtcgaatgtcggtcatacgcaggctgccgctggtgtggctggt
gtgatcaagatggtcatggcgatgcggcacggagtcctgccgaagacgcttcatgtggat
gagccgacggcggaggtggactggtcggcgggaaccgtcgcactgctgacggagcaggtg
ccgtggccgcgaagcgagcgtgtgcggcgagctggtgtctcctcgttcggtgtgagtggg
acgaatgcgcatgtggtgttggaggaggcgcctgttccggaggaggggcagttcgtcggg
gatgccccgttggctgtggtgccggtggtggtgtcgggtcgttcggcgggtgtggtggct
gagctggcgggccagatggggggtgtggctgggtctggtcggttggtggatgtggggttg
tcgtcggtggtgtcgcggtcggtgttcgagcaccggtccgtggtcctggccgaggactct
gtggagctgaataccggtctggatgctgtggcggccggtgtgccgtcgtctggtgtggtg
tcgggtgtggtgtcggtcgagggtggccggtcggtgttcgtgttccctggtcaggggacg
cagtgggtggggatggcggtccggttgtgggctgagtcgggtgtgttcgcggagtcgatg
gcgcggtgtgaggcggcgtttgagggcttggtggactggcggctggcagatgtgctgggt
gatgaggttgcgttggagcgggtggaggtggtgcagccggtcgcgtttgcggtgatggtg
tcgttggcggagttgtggcgttcgttgggtgtggtgccggatgcggtggtggggcattcg
cagggggagatcgctgcggcggtggtggcggggggtctgtcgttggaggacggggcccgt
gtggtggtgttgcgtgcggggttgatcgggcgtgagctggcgggccatggcgggatggcg
tcggttgcgctgccggtgggtgtggtggaggagcgtctggcgcggtgggcggggcgtctg
ggggtggcggtggtgaacggtccctcggccacggtggtcgccggtgacacggacgcggtg
gcggagttcgtgaccacatgtgagacggagggtgtgagggctcgccgtctgccggtggac
tatgcctcgcactcggcgcatgtggagacgctggcagctgagctggaagagatcctgtcg
gacgtccgtccggtgagcggtgagattccgttctactcgacggtagaggctggcctcgtg
gacacggcgtcgttggatgcggggtactggttcgggaatctgcgtcggccggtgcggttc
caggagacggtcgagcgtctcctcgcggatggtttcccggtgttcgtggaggccagcgcg
catccggtgctgacagctgcggtccaggagacggcggaatccatgggccggcaggtgtgc
gcggtcggttccctgcgtcgtgaggaggggggtctgggtcgtttcctgacctcggtggcg
gaagccttcgtccagggcgtggaggtgtcctggccggcactgttcgagggcaccggcgcc
cgcaccatcgacctgcccacttatcccttccagcaccagcgttactggcttgagtcgcgt
ccttctgcggcggttgttccgtcggggacgcaggacggtctgtcgtacgaggtgacgtgg
aagagtctgtcgttgccggagtcggtgcgtcttgacggccggtggctgctcgtcgtaccc
gagcacctggacgcggacggcacacgtgtcgcccacgacattcagcacgccctcaccacc
cacggcgccacggtctcccacctcacggtcgacgtgacggcgacggaccgcaccgacctg
tcggcgcggctcaccaccaccgcggccgaagagcaggaaccccttgggggaatcctgtcc
ctcctggggtgggccgagggtgcacaggtcgaccgcccgaccgtaccgattgccatcgcc
acctcactggcactggtgcaggccgttggcgacgcagggttcggtgttccggtgtgggcg
gtgacgcgaggtgcggtgtccgtggtgcctggtgaggtgccggagacggcgggtgcgcaa
ctgtgggcgctcggccgggttgccgctctcgaactccccgaccgctggggtggtctgatc
gacctcccggcgaacgccgatgcacgtacggcgggcctggcggtacgggcactggccgcc
gggatcgcggacggtgaggaccagttggcggtacggccctcgggtgcctacggccggcgc
gtcgttcaggcaggccaccggaagcccaagggcgcgaagccggaatggcgaccgcgcggc
accgtgctcgtcaccgggggaatgggcgccatcggaacccgggtggcccgctggctggcc
cggaacggagccgagcacctggtgctgaccggccgccgtggtgccgggacacccggcgcc
gacgagctggcgggagagctgagggcgtcgggcgttcaggtcacgctcgcggcctgcgac
gtgtccgatcgtgccgcgctggccgcgctgatcgacgcgcatccgccgaccgccgtcttc
cacaccgccggtgtgctgaacgacgggacggtcgacacgctcacccccggacgtctggac
ggggtcctgggccccaaggcgacggccgccgttcacctgcacgagctcaccgcacacctg
gaccttgacgccttcgtcctcttcgcctccgtcaccggcgtatggggtaacggcggccag
gccgcgtacgccatggccaacgcggctctggacgcgctcgccgagcagcgccgtgccggc
ggacttgcggcgacctccataagctggggcctctggggtggcggcggcatggccgagggc
aacggagaggtgagcctcaaccgtcgtggcatccgcgcgcttgagcccgccaccggcatc
gaggcgctgcaacggacgctcgaccaggacgcgacctgccgcaccgtcgtcgacgtggac
tggtctgagttcgctccgcgcacggccgcgctgcggcgcggacggcttttcgcggacctg
cccgaggcgcgacgtgcgctggggtcggaaggggccgcgcaggagggtgccggggccgcc
gagtcggccgccacatttgccgagcgcatcgcgtcgctgccggagcccgaacagcgtcgg
atactcgtcgagttggtccgagccgaggcggctgccgtcctgcggcacgacacgacggaa
ctcctggcgccgcgtaggtccttcaaggacgctgggttcgactcgctgaccgcgctggag
ctccgcaaccggctgagcaccgcgagcggtgtcgtccttcccgtcaccgtcgtcttcgac
cacccgaaccccggcgccctggcggacttcttgtacggcgaggccctgggcctgtccgcg
cagcacgtcgccgggagcgaccaggccgatacggcacggccggccatcgcccccgaagag
ccgatcgcgatcgtcggtatggcctgccgttacccgggcgaggcccactctcctgaggaa
ctgtggaagttgctcatggacgaacgggacgtcatcggccccatgcccactgatcggggt
tgggatgtggcgggtctgtttgatccggagccgggtgtgcctgggcgtacgtatgtgcgt
gagggtgggttcctgtatgaggcgggggagttcgacgcggggtttttcggtatttcgccg
cgtgaggcgttggcgatggatccgcagcagcggttgttgctggagacgtcgtgggaggcg
ttggagcgggcgggtatcgatccgaactcgctgcgcggctcacggacgggcgtctacgcg
ggcatgttccaccaggagtacgcggcccggctgcacgaagcgcccgcggagttcgaaggt
catctgctgacgggaacgtccggcagtgtcgcttcggggcgtatctcgtatgtgctgggt
ctggaagggccggcggtgacggtggacacggcgtgttcgtcatcgctggtcgcgctgcat
ctggcggtgcgggctttgcgcagtggtgagtgtgatctcgcgctggcgtgcggggtgacg
gtcatggcggagccgggtgtgttcgtggagttctcgcggcagcgggggctggcgtcggat
gggcggtgcaaggcgtttgcggctgctgctgatggcacgggctgggctgagggtgcgggc
gtactgctcgtcgagcgcttgtcggacgccgtgcgtcatggacatcgggtgttggcggtg
gtgcgtggttcggcggcgaatcaggacggtgcgagtaatgggttgacggcgccgaatggt
ccgtcgcagcagcgggtgatccggcaggcgttggcggatgcgcggttgggtgtgggtgat
gtggatgtggtggaggcgcatgggacggggacgcgtctgggtgatccgatcgaggcgcag
gcgttgctggcgacgtatggacagcgggacgcggggcggcctttgcggcttggttcgctg
aagtcgaatgtgggtcatacgcaggctgccgctggtgtggctggtgtgatcaagatggtc
atggcgatgcggcacggtgtgctgccgaagacgcttcatgtggatgagccgtcggcggag
gtggactggtcggcgggggcggtgtccttgctgacggagcaggtgccgtggccgcggggc
gagcgtgtgcggcgggctggtgtctccgcgttcggtgtgagtgggacgaacgcgcatgtg
gtgttggaggaggcgccggatgtgcgggagtcggtggagccgagtggtgaggggcttctt
ccggtggtgccggtggtggtgtcgggtcgttctgcgggtgtggtggctgagctggcgtcc
cgtatgggggaggtggcggggtctggtcggttggtggatgtggggtggtcgtcggtggtg
tcgcggtcggtgttcgagcaccggtccgtggtactggcggagaacgcaacggagttgaac
accggtctggacgccctggccgccggtgtggtgtcgcctggcgtggtgtcgggtgtggtg
tcggtcgagggtgcccggtcggtgttcgtcttcccgggtgcgggggcgaagtggtcgggg
atggcggcgcggctgtgggctgagtcggttgtgttcgcggagtcgatggcgcggtgtgag
gcggcgttcgagggcttggtggactggcggttgtcggatgtgatcgctcaggtgccgggt
gctgtgtcgttggagcgtgaggatgtggcgcagccggcctcgtttgcggtgatggtgtcg
ttggcggagttgtggcggtcgttgggtgtggtgccggatgcggtggtggggcattcgcag
ggggagatcgctgcggcggtggtggcgggtggtctgtcgttggaggacggggcgcgggcg
gtggtgttccggtcgcgggtggcggaggaggttttgtcgggtggggggattgcttcggtg
cgtctttcgcgggccgaggtggaggagcggttggcgggtgggggtggtgggctgagcgtg
gcggtggtgaatgcgccgtcgtcgacggtggtggctggtgagctgggagagttggagcgg
ttcgttgccgcgtgtgaggcggagggggtgcgtgcgcgtcggctggagttcgggtatgcg
tcgcattcggtgttcgtggagccggcgcgtgggcggttgctggaggcgctggccgacgtc
cgtccggtgagcggcgagatcccgttctactcgacggtggaagccgcggtgatcgacacg
gcgtcgttggacgcggggtactggttcgggaatctgcgtcggccggtgcggttccaggag
acggtcgagcagctgctcgcggacggtttccgggtgttcgtggagtgtggtgcgcatccg
gtgctgacggctgcggtgcaggagacggcggagtccgtgggccggcaggtgtgtgcggtc
ggttcgctgcgccgtgaggaggggggtctgcggcgtttcctgacctcggtggcggaggcg
ttcgtccagggcgtggaggtgtcctggccggcactgttcgacggcaccggcgcccggacc
gtcgacctgcccacctaccccttccaacgccagcactactgggcacaggcctcacccgcc
ggcagcggcagttccgctgcggcccgcttcggcatgacctgggaggagcacccgctcctc
agcggcgcgctgccgctcgcggagtccggtgagctgctgctcgtcgggcggatctccccg
gcctctcactcctggatcgccgaccacaccgtggccggcaccgccctgctgcccgggacc
gccttcgtcggcatggcgctgcatgccgccgcggtcgtgggctgcgcgggcgtggaggag
ctgagcatcgaggccccgctgccggtgcacggcggcatccggctccaggtggtgatcgac
gagcccgactcctccgaccggcgccgcgtgagcgtgttcgcgcggccggaggcggaagac
gggcacaccggtcggtggacccgacacgccaccggcgtactgacccctgccgccgccccc
gacccgggccggccgcagtggagccgcgaggcctggccgccgagcggttccgtccgcgcg
gagggggcggagctctacgaccggttctccgcgctgggatacgagtacggcgaggtgttc
gccggggtcgaggccgtctggctgcgcgagggcgaggtgttcgccgaggtccgcctgccc
gcgggcgcggcgccggacgccgagcggttcggggtgcaccccggcctcctcgacgcggct
ctgcaaccctggctgctgggcgacttcctgtcgcggcccgacgacggatccgtgctgctg
ccgttcgcgtggcgcggcatcacgctgtacgcgaccggtgccgatgcgctgcgggtccgc
ctgggcccggccggagaaggggccatgtcgctcgaagccgtcgacctcgccggtgccccg
gtgctgtcgatggacgcgctggtgctgcgtccgctcgcgcaggaccggctggtggaactg
gtcggcggcacgacgtccgcgccgctgtaccgcgtggactggcagcggagcccgatcgcg
aacacggcgccgtcggccacggggctcttcggctccttcccgtccggtgccacgcgccgg
tgggtggtcgtcgggcagggcggtgccgccgcacggtacgcgacggcggaccccggcacg
gggtgcgtcggggtcttccccgacctggacgcactgcgtacggcgctggactccggagcg
gaacgccccgacatcgtcctcgccgacttcggggcccggcccggcaccgccgccccgcac
gggacggctctggccgacggggtacgggacacggctcggcgggggctcgccctcgtccag
ggctggctgtccgacgagcgcttcgccgccgcacgcctcgccgtgctcaccgagcacgcc
gtcgccaccgaggcggacgagcggcaggtagacctcgccggatcggcgctgtgggggctg
atgcgttcggcgcagaccgagcaccccgaccgcttcgtcctcgtcgaacacgacgggcag
gacgcctcgtaccaggcgctgcccgccgctctcgacagcggaattccccaactggccctt
cgctcgggcaaggtccgcacgcccgggctggccgtcctgcccaccccgggagacgggctc
accgcgacgggcacggggttcgatcccgagggcaccgtgctcgtcaccggcgccaccggc
accctcggcagcctgctggcccggcacctggtcaccgcacacggcgtacggcatctgctg
ctgctcagccgcagcgggcgcgacgccggcagggccgccgaactggagcgtgaactcacc
ggtctcggcgccgagttccagctcctctcctgtgatgcgacggaccgggtagcgctgcag
gaggccctcgccaccgtccctgccgcacacccgctgaccgcggtgatccacacggccggc
gtcctggacgacggcgtcgtcgaggcgctgacccccgaacggctggaccgcgtgctgcgc
cccaaggcggacgccgcactgaacctgcacgagctgaccgcgggaatgccgctgaaggcg
ttcgtcctgtactccgggtcggtcggcctgctggggggggccggacaggccaactacgcg
gcggccaacgcgttcctggacggcctggctcagtaccggcacgcgcaggggctgcccgcg
gtgtccctggcatggggactgtggagcgccgccagcacgttcaccggccatctcggcgag
gtggatctgcgccgcatggagcggtccggcatcgcgccgctcacgaatgagcagggtctc
gaactgctcgaccgggcacttggtgccgccgcgggcgcggacgcgccgcagatctgtgcg
atgcggctggacacggcggcactgcgtcggcaggccgccgaacacgggcccgcttcggtg
cccctgctgctgcgtacgctggcggcgcccgccgtacggcgcggcgcggcgcgaacgggc
cgtggcgcacgggcggcgtccgcggtcacggacgtaccgagccgggcgcaagatttgcgc
gaacgactggccgggctggacgcggcgggaaggcgggacgaactcctggccgtggcccag
gcgcagttggccgacgtgctgggcttcaccgacaagaccgcggtcgaccccgttcgctcc
ttccgcgagatcggtctggactcgctgaccgccgtcgagctgcgcaacaggctcgatgcc
gtcaccggactgcggctgccgtcggcgctggtcttcgaccaccccaacctcgacgcgctc
gccggccacttggcggagctcctcatggcggagggcaaggacgacgcgggcgctgcggcg
ctgtcgggcatcgatgccctggaccgggcggtccggggcatggcggccgacgacacgcgg
cgtgacgccgtccgccgacgtctcacagaactgctggcggtggtcggccacgccccacgg
gacggcgaccgcagcacacgaacggccgccggcacaggaagccacggcgtgcaggcgggc
cccgacctgctggggcagctggactccgcctccgacgacgacctgttcgccttcatcgaa
gaccagttgtga

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