Streptomyces hundungensis: DWB77_05643
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Entry
DWB77_05643 CDS
T07388
Symbol
murF_1
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
shun
Streptomyces hundungensis
Pathway
shun00300
Lysine biosynthesis
shun00550
Peptidoglycan biosynthesis
shun01100
Metabolic pathways
shun01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
shun00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
DWB77_05643 (murF_1)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
DWB77_05643 (murF_1)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
DWB77_05643 (murF_1)
Enzymes [BR:
shun01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
DWB77_05643 (murF_1)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
Motif
Other DBs
NCBI-ProteinID:
AYG83447
UniProt:
A0A387HRB6
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All DBs
Position
6306308..6307714
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AA seq
468 aa
AA seq
DB search
MIALSLAEIAAIVGGQPHDIPDPSVTVTGPVVIDSRQVAAGSLFVAFAGEHVDGHDYAQR
AFEAGAVAVLAARPVGVPAIVVDDVQGALGALARDVVRRLGTDVVALTGSSGKTSTKDLI
AQVLQRHAPTVFTPGSLNNEIGLPLTALTAGPETRHLVLEMGARGVGHIRYLTGLTPPTI
GLVLNVGSAHIGEFGGREQIALAKGELVESLPEGGCAVLNADDPLVRAMASRTKARVLLF
GEAEDADVRAENVRLTAAGQPSFSLHTPSGCGDVTLRLYGEHHVSNALAAAAVAHELGMS
ADEIARALSEAGTLSRWRMEVTERPDGVTVVNDAYNANPESMRAALRALVAMGKGRRTWA
VLGPMAELGDESLTEHDAVGRLAVRLNVSKLVAVGGREASWLQLGAYNEGSWGEESVHVS
DAQAAVDLLRSELRPGDVVLVKASRSIGLERVAFALLDGAAEGEVAAR
NT seq
1407 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctccctcgccgagatcgccgcaatcgtcggcgggcagccgcacgacata
ccggatccgtccgtcacggtcaccggacccgtcgtcatcgactcccgccaggtggcggcc
ggttcgctcttcgtggccttcgccggcgaacacgtcgacggccacgactacgcgcagcgc
gccttcgaggcgggcgcggtggcggtcctggcggcccgcccggtcggcgtgcccgcgatc
gtcgtcgacgacgtgcagggcgccctcggggcgctggcccgcgatgtcgtacgccggctc
ggcaccgatgtcgtcgcgctgaccggctcgtccggcaagacgtccaccaaggacctgatc
gcgcaggtgctccagcgccacgcgcccaccgtcttcacgccgggctccctcaacaacgag
atcgggctgccgctgaccgcgctcacggccggcccggaaacccggcacctggtcctggag
atgggcgcgcgtggcgtcggccacatccgctatctgacgggtctgaccccgccgaccatc
ggtctcgtcctgaacgtcgggagcgcccacatcggcgagttcggcggccgggagcaaatc
gccctcgccaagggcgagttggtggagtccctgcccgagggcggatgcgccgtcctgaac
gcggacgacccgctggtacgcgccatggcgtcccgcaccaaggcgcgggtgctgctcttc
ggcgaggccgaggacgccgacgtacgggccgagaacgtgcggctcacagcggccggacag
ccctccttcagccttcacacaccctccgggtgcggcgatgtgacgttgcgcctgtacggt
gagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagctgggcatgtcc
gcagacgagatcgcccgcgcgctctccgaggcgggcaccctctcccgctggcgtatggag
gtcaccgagcgtccggacggtgtgacggtcgtcaacgacgcctacaacgcgaaccccgaa
tccatgcgagccgctcttcgcgcgctcgtggccatgggcaaggggcgccggacgtgggcg
gtgctcggtccgatggccgagctcggcgacgagtcgctcaccgagcacgacgcggtcgga
cggctcgccgtccggctcaacgtcagcaagctcgtggcagtcgggggccgggaggcgtcc
tggctgcaactgggcgcatataacgagggttcgtggggtgaggagtcggtgcacgtgtcc
gacgcacaggcggccgtcgacctgctgcgcagtgaactgcgcccgggtgacgtcgtgctg
gtgaaggcatccaggtcgatcggtctggagcgggtggcgttcgcgctgctcgatggcgcc
gccgagggtgaggtcgccgcccgatga
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