KEGG   Streptomyces kanamyceticus: CP970_29370
Entry
CP970_29370       CDS       T06849                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
ska  Streptomyces kanamyceticus
Pathway
ska00290  Valine, leucine and isoleucine biosynthesis
ska00620  Pyruvate metabolism
ska01100  Metabolic pathways
ska01110  Biosynthesis of secondary metabolites
ska01210  2-Oxocarboxylic acid metabolism
ska01230  Biosynthesis of amino acids
Module
ska_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:ska00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    CP970_29370 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    CP970_29370 (leuA)
Enzymes [BR:ska01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     CP970_29370 (leuA)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer
Other DBs
NCBI-ProteinID: QEU94464
UniProt: A0A5J6GIZ6
LinkDB
Position
6785594..6787315
AA seq 573 aa
MPNFQRPTSMPVHKYGRYEQVDITDRTWPNNRITVAPRWLSTDLRDGNQALIDPMSPARK
RAMFDLLVRMGYKEIEVGFPSSGQTDFDFVRSIIEDENAIPEDVTISVLTQAREELIERT
VESLKGARRATVHLYNATAPVWRDVVFRGSRDAVKQIAVDGTRLVMEYADKLLDDRTTFG
YQYSPEIFTDTELDFALEVCEGVMDVWQPDAEREIILNLPATVERSTPSTHADRFEWMSR
NLSRREFVCLSIHPHNDRGTAVAAAELAVMAGGDRVEGCLFGQGERTGNVDLVTLGMNLF
SQGVDPQIDFSDIDEIRRTAEYCNQMEIHPRHPYAGDLVYTAFSGSHQDAIKKGFDAMET
RAAGQGKTIDDIEWAVPYLPIDPKDVGRSYEAVIRVNSQSGKGGIAYVLQNDHKLDLPRR
MQIEFSRIIQAKTDAEGGEVTPGAIWSVFQDEYLPNPDNPWGRIQVKNGQTTTDTDGVDT
LTVEATLDGADTVLTGTGNGPISAFFGALQGIGIDVRLLDYQEHTMSEGASAQAASYIEC
AIGDKVLWGIGIDANTTRASLKAVVSAVNRAAR
NT seq 1722 nt   +upstreamnt  +downstreamnt
atgccgaacttccagcgccccacatccatgccggtccacaagtacggcaggtacgagcag
gtcgacatcaccgaccgcacctggccgaacaaccggatcacggtcgcgccccgctggctc
tccaccgacctgcgcgacggcaaccaggccctgatcgacccgatgtccccggcccgcaag
cgcgccatgttcgacctgctcgtacgcatgggctacaaggagatcgaggtcggcttcccc
tcgtcgggccagaccgacttcgatttcgtacgctcgatcatcgaggacgagaacgcgatc
cccgaggacgtgacgatctccgtcctgacccaggcgcgcgaagagctgatcgagcgcacg
gtcgagtccctgaagggcgccaggcgcgccaccgtgcacctgtacaacgcgaccgcgccc
gtctggcgcgacgtcgtcttccggggttcgcgcgacgccgtgaagcagatcgccgtggac
ggcacccggctggtcatggagtacgccgacaagctgctcgacgaccgtacgaccttcggg
taccaatacagccccgagatcttcacggacaccgagctggacttcgccctggaggtctgc
gagggcgtcatggacgtctggcagcccgacgccgagcgcgagatcatcctcaacctgccc
gccacggtggagcgttccacgccctccacgcacgcggaccgcttcgagtggatgtcgcgc
aacctgtcccgccgcgagttcgtctgcctctccatccacccgcacaacgaccgcggcacc
gccgtcgccgccgccgagctggccgtgatggcgggcggcgaccgcgtcgagggctgcctg
ttcggccagggcgagcgcaccggcaacgtcgacctggtgacgctgggcatgaacctcttc
agccagggcgtcgacccgcagatcgacttctcggacatcgacgagatccgtcgtacggcc
gagtactgcaaccagatggagatccacccgcgccacccctacgcgggcgacctcgtctac
accgccttctccggctcccaccaggacgccatcaagaagggcttcgacgcgatggagacc
cgggccgcgggccagggcaagaccatcgacgacatcgagtgggccgtgccgtacctgccc
atcgaccccaaggacgtcggccgctcgtacgaggccgtcatccgcgtcaactcccagtcc
ggcaagggcggcatcgcgtacgtcctgcagaacgaccacaagctggacctgccgcgccgc
atgcagatcgagttctcgcggatcatccaggcgaagaccgacgccgagggcggcgaggtc
acgccgggtgcgatctggagcgtcttccaggacgagtacctgcccaacccggacaacccc
tggggtcggattcaggtcaagaacggccagacgaccaccgacacggacggcgtcgacacg
ctcaccgtcgaggccaccctcgacggcgccgacaccgttctgaccggtacgggcaacgga
ccgatctccgcgttcttcggcgcgctgcagggcatcggcatcgacgtacgcctgctcgac
taccaggagcacacgatgagcgagggagcgtccgcgcaggccgcctcgtacatcgagtgc
gcgatcggcgacaaggtcctgtggggcatcggcatcgacgcgaatacgacacgtgcgtcg
ctcaaggccgtggtctccgccgtgaaccgggccgcgcgctga

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