Sander lucioperca (pikeperch): 116066263 Help Entry 116066263         CDS       T07345                                  Symbol ryr3 Name (RefSeq) ryanodine receptor 3 isoform X2   KO K04963   ryanodine receptor 3 Organism sluc  Sander lucioperca (pikeperch) Pathway sluc04020   Calcium signaling pathway sluc04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:sluc00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     116066263 (ryr3)    04020 Calcium signaling pathway     116066263 (ryr3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:sluc04040]     116066263 (ryr3) Ion channels [BR:sluc04040]  Voltage-gated cation channels   Ryanodine receptor    116066263 (ryr3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_8 EF-hand_1 Med16_bridge Motif Other DBs NCBI-GeneID:  116066263 NCBI-ProteinID:  XP_031178089 Ensembl:  ENSSLUG00000001368 LinkDB All DBs Position 19:9297056..9431312 Genome browser AA seq 4887 aa AA seqDB search MAVDELYANIGLRGTASHFCRQSVVASRVCAGSFTAMAEGGEGEDEIQFLRTDDEVVLQC VANIQKEHRKFCLAVEGLGNRVCYLESTSEAKYVPPDLCICNFVLEQSLSVRALQEMLAM TGQNSEGSADHEKWGGQGGGHRTLLYGHAILLRHSFSDMYLTCLKTSRSLTDKLSFDVGL QEDSIGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSTERYLHLSFSNGNINVDASFMQ TLWNVQPTCSSGNVAVGYLTGGHVMRLCHGHDESLTIPGADKSQEEQRIVNYEAGKGASR ARSLWRLEPLRISWSGSHIRWGQSFRLRHLSTGHYLALTEDRGLVLQDRDKCDTTSTAFC FRASKEKGDTGPKRDIEGMGVPEIKYGDSVCFVMHVATGLWLSYLAPDAKSSRLGPLKRR ACLHSEGHMDDGLILQRCQHEESRAARIIRNTTLLFANFIKALDSLAEGESMAVAGYVEE VLQTLNDLIEYFKQPDSELEHEEKQCLLRSLIKRQDLFKEEGMLVLLSICIDRMNLYNSS AHFGEVAGEEAGAAWKDILNLLYELLAALIRGNRNNCTQFSRKLDWLVSKLERLESSSGI LEVLHCILVESPEALNIIQRGHIKSIISLLYKHGRNHKILDVLCSLCVCNGVAVRTNQNL ICDNLLPKRDLLLQTRLVNDVQSMRPNIFLGVAEGSAQYKKWYFEVVTDQVDHFVTGEPT HLRVGWANTKGYAPYPGGGEGWGGNGVGDDLYSYSFDGLHLWSGRVPRAVASINQHLLNS DDVVSCCLDLGAPSMSFRINGQPVQGMFEDFNTDGLFFPVVSFSAGVKARFLLGGRHGDF KFLPPAGYSPCYEALLPKEKMHVEPVKEYKRDHDGVRDLLGTTKFLSQASFIPTPVDTSQ IVLPPHLDNVRDKLAENIHELWGMNKIELGWTYGKVRDDNKRQHPCLVDFSKLPETERNY NVQMSSETLKTLLALGCHVSQVYVNAEDDLKKIKLPKDYMMSNGYKPAPLDLSDVKLTAG QEVLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKSRRNPRLVPYALLDERTKKSNRDSLR EAIRTMVGYGYDIDPPDQEAPHTMEDENVENIRFFRVEQTYAVKTGKWYFEFEALSGGDM RVGWARPGCRPDVELGTDDQAFVFDGYRGRRMHAGSRYFGQTWKKGDVVGCMINMEDKSM IFTLNGELLITSKGSELCFTDFETEDGFIPVCSLGVTEIGHINLGKDASTFKYYTMCGLQ EGFEPFGVNMNREITMWFSKRLPTFVNIPQDHMHIEVTRIDGTVDSPPCLKVTHKTFGTQ NSNSDMVYCRLSMPVEFYSADKLLDESLKLSHPPKEDGTVDYGSITTYYHSVRVFAGQDP ASVWVGWVTPDYHYYSKNFSLAKTRTVTVTLGDERGRVHESVQRSNCYMVCGADAVGPSS SSNSDLEIGCLIDLATGLVSFTANGKELSATYQVEPNTKLFPAVFVLPTSANLFQFEFVK IKDAMPLSSAIFKSEHRNPVPQCPPRLDVQTIVSVLWSRMPNTFLNVETARVSERHGWVV QCLEPLQMIAVHIPEENRCLDIMELSEHEDLRKFHYHTLKLYCALCALGNTRVAHALCSH LDQSQLLYTIDNQYLSGMLREGFYNVLISIHLETAKEARLMMNNEFIIPVTDETRSIKLF PDESKRHSLPGVSLSTSLKPRVNFSAVGIINTKRQQFLYSPQIPLGILKEKAISMLTEAV QGGGTHIRDPVGGSVEYQFVPILKLIGTLLIMGVLTSDEVRLILLLIDPNVFGEAKEGQE AKGDEVAVVGVKEEVSKNEEKAVEAGEEETKESKPQVKGLLEKSLPESVKRQMCELLHYF CDCELKHRIEAIVSFSDSFVSKLQFNQKFRYDELMLAFNMSAAVTAKKTKEFRSPPHEQI NILLNFSAGEDCPCPEEIQNELNSFHEELRLHCGIPVEEEEEEQDTSIKGRLLALLYKIK GQPQKTEEEPTEKEQAAPTNLKELISQTITSWAQESHIQDPELVRVIFSLLRRQYDGIGE LLRAMKKSYTISAASVQDAINLLVSLGQIRSLLSVRMGKEEEKLMIDGLGDIMNNKVFYQ HPNLMRVLGMHETVMEVMVNVLGGDKSQEIAFPKMVASCCRFLCYFCRISRQNQKAMFDH LSYLLENSSVGLASEAMRGSTPLDVAASSVMDNNGLALALEEPDLEKVVTYLAGCGLQSC AMLVAKGYPDLGWNPIEGERYLSFLRFVVFCNGESVEENANVVVKLLIRRPECFGPALRG EGGQGLLAAMKEAIKISDDPALDLPNIPTVVTTGSGEEEGEVIHMGNAIMSFYSALIDLL GRCAPEMHLINAGKGEALRIRAILRSLVPTSDLVGIISIPLKMPVLNKDGTVTEPDMSAC FCPDHKAPMVLFLERVYGIEDQSFLLHMLEVGFLPDLQASASLDTEVLSTTETALAMNRY IGSALLPLLTRCAALFSSTEHYAQLVDSTLQTIYRLSKGRSLTKAQRDAIEECLLAICKH LRPSMMQQLLRRLVFDVPMLTEYCRIPLRLLTNHYEQNWKYYSLPSGMGSFGIASEEELL LTKKLFWGIFDSLSQKKYDADLFKIAMPCLCAIAGALPPDFVDASLGATLEKQASMDAQG NFDPKPINTANISLPEKLEYIANKYAEHSHDKWSSEKVSAGWKHGDSLNEQAKTHPLLKP YKALSEKERETYRWPVRESLKSMLAMGWNIERTKEGDAMLQQQQQSEKQRKISDSQINEF SPAPMDLHNVNLSRELQGMVEVVAENYHTIWAKKKKTELVSKGGGTHPLLVPYDTLTAKE KYRDREKAQELFKFLQISGYAVIRGLKDIEQDSSSMEKRFAYKFLKRLLKYIDSAQEFIA HLEAMATSGKTDKSPHDQEIKFFAKVLLPLTDQTLKNHCLYFLSTPSKNLSSCGCASNKE KEMVTSLFCKLAALVRHRISLFGSDSAMMVSCLHILTHSLDTRTVMKSGSELVKAGFRNF FENAAEDLDKLLEMLKLGKFMQSRAQMKSVTQSINYVTVALLPILTALFEHITTYGFGVD LLLDDVQLSCYRILNCFYSLGTGKNVFVERHLPALGESLATLVGAMPVAFLEPQLNAHNP LSVFNTKTPRERAILSMPDTVEEMSPEMPRLDRLLKDVSDVSESGARYSDMPQVIEVILP MLCNYLSYWWEKGPENSPPGANCCTMVTSEHLSIILGNILKILNNNLGIDDAPWMKRIAV YSQPIICKAGADLLRTHFLPTLDKLRKKTVKVVGEEELLKADGKGDNQEAELLILDEFAV LCRDLYAFYPMLIRYVDNNRCRWLKEPDADSTELFRMVAEIFILWCKSHNFKREEQNFVV QNEINNLGFLTGEGKAKMSKSGGDQERKHKRRRGEYYSIQTSLIVAALKKLLPVGLNMCT PGDQELISLAKIRYSLKDTDDEVKEHLRQNYHLLDKSDDPAVQWQLNLYKDVVVKSEEPA NLEHTVDRVQSISAAVFHLDQVELPLRNKKCVMHKLLSKQRKRAVVACFRMAPLYNLPRH RAINFFIPAYQRLWIEAEEYSFEEKLVQDLAKTPMKIVEEEEEEVAEIQPDPLHQLILHF SHNALTERSHLEEDPLYIAYADMMAKSCAEDEEEEEVEGKEKTFEEKEMEKQKILYQQAR LHARGAAEMVLQMIGSSKGRLGPMVSCTLKLGISILNGGNVQVQQKMLDYLKEKRDAGFF KSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGSIHTQQGSKVLQNDEFTKDLFRFLQL LCEGHNGDFQNFLRTQTGNTTTVNIIISTVDYLLRLQESISDFYWYYSGKDVIDETGKLN FSKALYVAKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDASQI ELLKELMDLQKDMVVMLLSLLEGNVVNGTIGKQMVDTLVESSNNVEVILKFFDIFLKLKD LTSSDSFREYDPECKGIISKKEFQKSMESQMQYSQSEIEFLLSCAEADENDMFSYKEFVE RFHEPAKDIGFNIAVLLTNLSEHMPHDSRLATFLDLAESVLSYFEPYLGRIEIMGSAKRI ERVYFEISESSREQWEKPQVKESKRQFIFDVVNEGTESEKMEMFVNFCEDTIFEMQLASQ ISEPDVGEQPEEEEEEDAHSVMDEAAGEEEGTLESASAFTTACRSVKKKIGHVRQIFTVK NVRKQFKKIKKLSIKEIITSFFSFFWMLFTGFFKGIYGLIFGFFHVIWSSMFGGGLVEGA KNIKVTDILGNMPDPTQFGIHGDVIEGEKVEAIESTGSLDDAISPAGDLAEVDAMLEMLS NPKREGGKHIELGLGDVSELSAETSTTDQKKAAAKPVVTPENEPEKADTENQEKEDKPKD EAKEPVAEEKPKTKSSQPKGATPAFMMSIVAGLDVLMTKIVNYLARNFYTLRFLALFVCF AINFILLFYKVTEPDEEIDEESTWDGEDEDDVDTLFDMDEFSLQESTGYMLPTLRFLAIF HTVISLVCLVGYYCLKVPLVVFKREKEIARKLEFDGLYITEQPSDDDIKGQWDRLVINTP SFPSNYWDKFIKRKVINKYGDLYGAERIAELLGLDKSALDFDPTVETVEKEASLLSWLSS IDTKYHIWKMGVVLTDNYFLYLIWYATMSVFGHFNNFFFAAHLLDIAMGFKTLRTILSSV THNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVG VRAGGGIGDELEDPAGDPYELYRILFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQV KEDMETKCFICGIGNDYFDRTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYV WKMYQERCWDFFPTGDCFRKQYEDQLG NT seq 14664 nt NT seq  +upstreamnt  +downstreamnt atggctgtggatgagctgtatgctaatatcggcttgagaggcacagcatcacatttctgc cggcagtcagtggtggcttccagagtctgtgcaggctccttcacagccatggctgagggc ggagaaggggaagacgaaatccagttcttgagaactgatgacgaggtggtgctccagtgt gtggccaacatccagaaggagcatcgcaagttctgcttggccgttgaaggactgggaaac cgtgtgtgttacctggaatccacatctgaagctaagtatgttcctccagacttgtgtatt tgtaactttgtgttggagcagtccctgtcggtgcgggccctgcaggagatgctggctatg actgggcagaacagcgaagggagtgctgaccatgaaaaatggggaggtcaggggggtgga caccggaccctgctctacggtcatgccatcctccttcgccactccttcagtgatatgtac ctgacctgtttgaagacatcaaggtctctgacagacaagctgtcatttgatgtcggacta caagaagattctataggagaggcttgctggtggaccatccaccctgcgtccaagcagaga tccgagggagagaaagtccgcattggagacgacctgatcctagtcagcgtgtcgacagag agatacctgcacctctccttctccaatggcaacatcaatgtggacgcctccttcatgcag accctgtggaacgtccagcctacctgctcttcaggcaacgtggctgtaggctatctaact ggtggacatgtgatgcgtctttgtcatgggcatgatgagagcttgaccatccctggagcc gacaagagtcaggaggagcagaggatagtcaactatgaagctggtaagggagcgtcaagg gcccgctcactctggagactggagcctctccggatcagctggagcggtagccacatccgc tggggtcagtccttccgactacgccacctctctactggccattacctggccctgactgag gaccgcggactggtcctgcaggacagggacaagtgcgacaccacgtccactgctttctgc ttcagggcctccaaggaaaagggtgacacaggcccaaagagggacatcgaaggcatggga gtaccagagatcaagtacggagactccgtctgcttcgtcatgcatgtggcgacgggactg tggctttcttacctggcgcctgatgccaaatcatctcgcctaggacccctgaaaagaagg gcgtgcctgcattctgagggccacatggacgatgggcttatcctgcagcgctgtcagcat gaggagtctcgggctgctcgcatcatccgcaacaccacgctcctctttgccaactttatc aaagctttggacagccttgcggagggtgagtccatggcggtagccggttatgttgaagag gtgctgcagacattgaacgacctgatcgagtactttaaacagcccgattcagagctggag cacgaggagaaacagtgtcttcttcgttccctcatcaaacgtcaagacctcttcaaagag gagggcatgctggtcctcctgtccatatgcatcgaccggatgaacctgtacaacagttct gcccattttggagaagttgctggggaggaggcgggcgcagcatggaaggacattctcaat ctcctctatgaactcttggccgcactgattcgtgggaacagaaacaactgcacccagttt tcccgcaaattggactggttggtcagcaaactggagagactggaatcttcatcagggatc ctggaagtcctccactgtatcttggtagaaagtccggaggctctgaacatcattcagaga ggtcacattaaatccatcatctctctactctacaagcatggacgcaaccataagattctg gatgtcctgtgttctctctgtgtttgcaacggggtggcagtgagaaccaatcagaatctg atctgtgacaacctgcttccaaagagggacctgctgcttcagactcgactggtcaatgat gttcagagtatgaggccgaacatcttcttgggcgtggctgaaggttcagctcagtataag aagtggtattttgaggtggtgactgaccaggtggaccactttgtaaccggagagccgacc cacctgagggtaggctgggccaacactaaaggctacgctccgtaccccggtggaggagag ggatggggtggcaacggtgtcggggatgacctctactcttacagctttgatggacttcat ctctggtcaggccgagtcccaagggccgtggcctccattaaccagcacctgctgaactca gacgatgtggtcagctgctgtctagatttgggcgctcccagtatgtccttcaggatcaac gggcagcctgtccagggcatgttcgaggacttcaacaccgatggattattcttccccgtc gtcagcttctctgccggtgtcaaggcccgtttcctgttgggtggacgccacggagatttt aagttcctgccacccgctggttactctccatgctacgaggcgctgttgcccaaagagaag atgcatgtagagcctgtgaaggagtacaagagggaccatgatggggtccgtgacctgctg ggaaccaccaagttcctctctcaggcctccttcatccccactcctgttgacaccagccag attgttcttccccctcacctggacaacgtccgggacaagctggcagaaaacatccacgaa ctgtgggggatgaacaagattgaactgggctggacctatggcaaggttcgtgatgacaac aagaggcagcacccttgccttgtggatttcagcaagctgcctgaaactgaaaggaactac aacgtgcagatgtctagtgaaacacttaagaccctgttggctcttggatgccatgtttcc caggtctatgttaacgctgaggacgatctgaagaaaataaaacttcccaaagactacatg atgtctaatggttataagcctgcgccactggacctctctgacgtgaaactgacagcaggt caggaggttctagttgataaactggccgagaatgcacacaacgtgtgggccaaagacaga attaaacaaggatggacctatggcatccagcaggatttgaagagcaggcgtaatcctcgc ctggtgccatacgctttactagacgagcgcacaaagaaatctaacagagacagtctgaga gaggccatcaggaccatggttggatatggatatgacatcgaccccccagaccaggaggcc ccccatacgatggaagatgagaacgttgagaacatccgcttcttccgtgtggagcagaca tatgcagtgaagacgggaaagtggtactttgagtttgaggccctgagcggaggcgatatg agggttggctgggccagaccaggctgcaggcccgatgtcgaactgggaacggatgaccag gccttcgtcttcgatggatacaggggtcgacgtatgcacgcaggcagccgctactttgga caaacttggaaaaagggtgacgtggttggttgtatgattaacatggaggacaaatccatg attttcaccctaaatggagagctcctgatcaccagcaagggctctgagctttgcttcact gactttgagacagaggacggtttcatccccgtgtgcagtctgggtgtgactgagattgga catataaacctgggcaaggacgccagcactttcaagtactacaccatgtgtggtctccag gaagggtttgagcccttcggtgtcaacatgaacagagagatcaccatgtggttcagcaag cgccttcccacctttgtcaacataccccaagaccacatgcatatcgaggtgacgaggatc gacggaacggtagacagccctccctgcctcaaggtcacccacaagacttttggcacgcag aacagcaacagtgacatggtctactgtaggctgagcatgcctgtggagttctactcggca gacaagttactggacgaatcactgaagctcagccatcctccaaaagaagatggaactgtt gactatggaagcatcacaacttactaccactcagtgagagtgtttgctggacaggaccct gcgtcagtgtgggtgggttgggtcacaccagactatcattactatagcaaaaacttcagc ctcgccaagacacgaacagtcaccgtcaccctgggagacgagaggggccgggtccatgag agtgtccagaggagtaactgctacatggtgtgtggagcggatgcagtcggcccgtcttcc tccagcaactctgacctggagatcggctgtctgatcgacctggccactggcctggtgtct ttcactgccaacggcaaggagctgtctgcaacatatcaggtggagccaaataccaagctg ttcccagctgtgtttgtcctccccaccagtgcaaaccttttccagtttgaatttgtgaag atcaaggatgcgatgccgctctcgtctgccatatttaagagtgagcacaggaacccagtg ccgcagtgcccgccacgtctggatgtgcagaccatcgtgtccgtgctgtggagccggatg ccaaacaccttcctcaacgtggagactgctcgggtcagcgagaggcacggctgggtggtc cagtgtctggaaccgcttcagatgatagccgtacatatacctgaggagaataggtgtttg gacatcatggagttatctgagcatgaagacctgagaaagttccactaccacacactgaag ctgtactgtgccctgtgtgccctgggaaacacccgagttgctcacgccctctgcagccac ttggaccaatcccaactcctctacaccattgacaaccagtacctctctggcatgctgaga gagggcttctacaatgtccttatcagcatccatcttgagactgcaaaggaggctcgcctg atgatgaacaacgagttcatcatccctgtgacggatgagacccgctccatcaagctgttc cctgatgagtccaagcggcactcgctgcctggcgtgagcctgagcacctccctcaaacct cgggtcaacttctccgccgtcggcatcatcaacacaaagcgccagcagttcctctacagc ccccagattcctctgggcattctgaaagagaaagccatcagcatgctcactgaggccgtg cagggcggaggaacacacatccgagacccggtaggcggtagcgtggagtaccagttcgtt cccatcctgaagctgattggaacgctcttaataatgggagtcctaaccagtgacgaggtg aggctgattctcctcctgattgaccccaacgtgttcggagaggccaaggagggtcaggaa gccaagggggatgaggtggctgtggtgggggtgaaggaggaagtgagcaagaacgaggag aaggctgtggaggcgggagaggaggagacaaaggagagtaaaccgcaagttaaaggtttg ctggagaagtcgctgcccgagtctgtcaaacgccagatgtgtgagctgctgcactacttc tgcgactgtgagctgaagcaccgtatcgaggccatcgtctccttctccgacagcttcgtg tccaagctgcagttcaaccagaagttccgctacgatgagctgatgctggcgtttaacatg tccgccgctgtcactgccaagaagactaaagagtttcgttcacccccacatgagcagatc aacatcctgttgaatttcagtgcaggggaggactgcccctgccccgaggagatccagaat gaactcaactccttccatgaagaattgcgactgcactgtggaattcccgtggaggaggaa gaggaagagcaggacacttctataaaaggccgtctcctcgctttactctacaagatcaaa ggtcaacctcagaaaacagaggaggaacccacagagaaggaacaggcagctcccaccaac ctgaaggagctgatctcccagaccataacaagctgggctcaggagtctcacatccaggac ccagagctggtcagagtgatattcagcctgctaaggaggcagtatgatggcatcggggag cttctccgggccatgaagaaatcctacaccatcagtgctgcgtctgtgcaggatgccatc aacctgttggtatcgctaggtcaaatcaggtcacttctgtcagtacgcatgggcaaagag gaggagaaattgatgattgatggactcggcgacatcatgaacaacaaggttttctaccaa catcccaacttaatgagagtgctgggcatgcacgagactgtcatggaggtcatggtcaac gtgctgggaggagacaagtcacaggagatcgccttccccaagatggtggccagctgttgt cgtttcttgtgctacttctgtcgtatcagccgccagaaccagaaagccatgtttgaccac ctgagctacctgctggagaacagcagtgtggggctggcctctgaagcaatgcggggctcc actccgctggatgttgcagcatcttcagtgatggacaacaacggcctggctttggccctg gaggagcctgatttggagaaggtggttacatacctggcaggctgtggtcttcagagttgt gccatgctggttgctaagggttaccccgacctcggctggaaccctatagagggagagcgc tacctgtccttcctgaggttcgtcgtcttctgcaatggtgagagtgtggaggaaaatgcc aacgtggtggtgaagctgctgatcaggcgtccagagtgtttcggccccgccctgagggga gaggggggtcaaggtctgctggctgccatgaaggaagccattaagatctctgatgatcct gccctggacctgcccaatatccccactgtggtcactactgggtctggtgaggaagaaggt gaagttattcacatgggcaacgccatcatgtccttctactcagctcttattgacctgctg ggccgctgcgctcccgagatgcatcttatcaatgcgggtaaaggtgaggcgctgcgtatc cgagcaatcttgcgctctctggttcccacgtcagacctggtgggaatcatcagcatcccg ctcaaaatgcctgtgcttaataaagatggcacagtgacagaacccgacatgtcagcctgt ttctgtccggaccacaaggcccccatggtgctcttcctggaacgagtgtacggtatcgag gaccagagcttcctgctccatatgttggaggtcggcttcctgcctgacctccaagcctct gcgtctttggacacggaagtgttgagcaccactgaaacggcgttggccatgaataggtac atcggctcggccctgctgcctctgctcacccgctgtgccgctctctttagcagcacagag cactacgcacagctggttgactcaacgctgcagactatctaccggctgtccaaaggacgc tcactcaccaaagcccaaagggacgccatcgaggagtgtctgctggctatctgcaagcac ctgcgtccctccatgatgcagcagctgctcaggcggttggtgttcgacgttcccatgctc actgaatactgccggatacctctcaggcttctgaccaaccactatgagcagaactggaag tactactccctgccttctggtatgggcagctttggcatagcctccgaggaggagctcctc ctaaccaagaaactcttctggggaatctttgactccctttcccagaagaagtatgatgct gaccttttcaaaatagccatgccatgcctgtgtgccatcgctggagccttgcctccggac tttgtggatgcaagtcttggagcaacactggagaaacaggcatcaatggatgcacagggc aactttgatcccaaacccatcaacactgccaatatctcccttcctgaaaaacttgagtac attgccaacaaatatgcagagcattcccatgacaagtggtcctcagagaaggtgtcagca ggctggaaacatggagacagcttgaatgagcaggccaaaacccatccactgctgaagcct tacaaagcgctgagtgagaaggaaagagaaacataccgctggccagtgagggagtcattg aagagcatgctggctatgggctggaacattgagaggaccaaagaaggagacgccatgtta caacaacaacaacagagcgaaaaacagcgaaagatctctgactctcagatcaatgaattc agtcctgctccgatggacttgcacaatgtcaatttgtctcgtgagttacagggcatggtg gaggtggttgcagaaaactaccacaccatctgggccaagaagaagaaaactgaactcgtt agcaaaggaggagggacccacccactgttggtaccctatgacaccctgacggctaaagag aagtacagagacagagagaaggcccaggagctcttcaagtttctgcagatcagtggctat gccgtcataagaggtctgaaggacatagagcaggattcatcatccatggagaagcgtttt gcctacaagtttctcaaaaggctgctgaaatacattgactcggcccaggagttcattgct catcttgaggctatggccaccagtgggaagacggacaaatcacctcatgaccaggaaatc aagttctttgccaaggtgttgcttcctctgacagatcaaactttaaagaaccactgtctc tacttcctgtccacacccagcaagaacctgagcagctgtggctgcgcctctaacaaagag aaggagatggtcactagcctgttctgtaagctggcagctcttgtcagacacaggatttct ctctttggaagtgactctgcaatgatggtgagctgtctgcacatccttactcactcactt gacaccagaacggtgatgaagtctggctcagagctggtcaaagccgggtttcggaatttc tttgagaacgcggcagaggacctggataagctgctggagatgctaaaactggggaagttc atgcagtcccgtgcccagatgaagagcgtcacccagagcatcaactatgtgactgtggcg ctgctgcccatcctcactgccctgtttgagcacatcacgacatacgggtttggagtggac ctgctgttggatgatgtgcagctgtcctgttaccgaatcttgaactgtttctactctctg ggaactggaaagaacgtctttgtggagaggcatcttccagcgctgggggagagcctggca accctggtgggagccatgcctgtggcgttcctagagccccaattaaatgcccacaacccg ctgtctgtctttaacaccaagaccccccgagagagagccatcctgagtatgccggacacg gtagaggagatgtctccagagatgcctcgtcttgacagactgctgaaagatgtcagcgat gtctcagagtctggtgctcgctacagtgacatgccacaggtcattgaagtgatccttccc atgctgtgtaactatttgtcctactggtgggagaaaggtcctgagaactcacctccaggt gccaattgctgcactatggtgacctctgaacacctcagcatcatcctgggaaacatcctc aagatccttaacaacaacctgggcatcgatgacgccccctggatgaagaggattgcggtc tactctcagccaatcatctgcaaggctggagcagatctgctgagaacccacttcctgccc acactggacaaactgaggaagaagacagtgaaggttgtgggtgaagaggagctgctgaag gctgacggtaaaggtgacaaccaggaggccgagctgctcatcctggatgagtttgctgtg ctctgcagagacctctacgccttctaccccatgctcatccgttatgtggacaacaacagg tgcaggtggctgaaggagccagatgcagactccactgagctcttcaggatggtggcagag atcttcatcctctggtgcaagtcccataactttaagcgtgaagagcaaaactttgtggtt cagaatgagatcaacaatttgggcttcctgactggagagggcaaggcaaagatgtccaag tcagggggggaccaggagaggaaacacaagcgccgccgaggcgagtactactccatccag acctccctgatcgtggctgccctgaagaagctgctgccagtcggcctaaacatgtgcacc ccaggagaccaggagctcatctcccttgccaagatacgctacagtctgaaagacacagat gatgaggtgaaggagcacttgcgtcagaattaccatctcctggacaagtctgatgaccca gcagtccagtggcagctgaacctgtacaaggacgtggtggtaaagagcgaggagcctgca aacttagaacacacagtggaccgagtgcagagcatctcagctgcagtcttccacctggat caggtggagctgcctctgagaaataagaagtgtgtgatgcataagctgctgtccaaacag cgtaagcgtgctgtggtggcttgtttccgcatggctccactctacaatctacccaggcat cgcgctatcaacttcttcatcccggcctatcagagactttggatagaggcagaggagtac tcctttgaggagaagctagttcaggatctggcaaaaaccccaatgaaaattgtggaggag gaggaagaggaggtggctgagatccagccagaccctctccaccaacttatcctccacttc agccacaacgctctgacagagagaagtcacttggaagaagatcctttgtatattgcgtat gcagacatgatggcaaagagctgtgcagaggatgaggaggaagaagaggtggaagggaaa gaaaagacttttgaggaaaaagagatggaaaagcagaagatcctgtatcagcaggcgagg ctgcacgcccgtggggccgcagagatggtgctgcagatgatcggctccagtaaaggtcgt ctgggccccatggtgtcctgcaccctcaaactgggaatctccatattaaatggaggcaat gtgcaagttcagcagaaaatgcttgattacctgaaagagaaaagagatgcaggctttttc aagagtctctcaggactgatgcagtcttgcagtgtcttggacttgaatgcatttgagagg cagaacaaagcagaaggacttggcatggtgacagaggagggttcaatccacactcagcag ggttccaaggtgctacagaatgatgagtttactaaagatctgttccggtttttgcaactt ctgtgtgaggggcacaatggagattttcaaaactttctgagaactcaaactggaaacaca accacagtcaacatcattatcagcactgtggactatctgctccgtcttcaggagtctatc agtgacttctactggtactactctggcaaagatgtcattgatgagactggaaaattaaac ttctctaaagcattatatgttgccaagcagatattcaactcactgactgagtatattcag ggcccgtgtattgggaaccagcagagtttagctcacagcagactgtgggatgcagttgtg ggcttcttgcatgtatttgccaacatgcaaatgaagctgtctcaggacgccagtcagatt gagctgttgaaggagctgatggatttacagaaggacatggttgtcatgttgttgtctctg ctagagggtaatgtggtgaacggaacaattggaaagcagatggttgacactctggtggag tcttctaacaatgtggaggtgatccttaagttcttcgatattttccttaaactgaaggac ctgacgtcctctgacagcttcagagagtatgaccctgagtgtaaaggcattatttcaaag aaggagttccagaagtcaatggaaagccagatgcagtacagccagtctgagattgaattc ctgctctcgtgtgcagaggccgatgaaaatgacatgttcagttacaaagagtttgtggag cggttccacgagccggctaaagatattggcttcaacatagcagtgctgttgaccaacctg tctgaacacatgccacatgactccagactcgccacctttttagacctggcagagagtgta cttagctacttcgagccttatctgggtcgtatcgaaatcatgggcagcgcaaaacgcatt gagagggtgtactttgagatcagcgagtcaagccgtgagcagtgggagaagccgcaggtg aaagagtccaagcgtcagttcatctttgatgtggtcaacgagggcacggagagcgagaag atggagatgtttgtgaatttctgcgaggacacaatttttgagatgcagctagcctcacag atctctgagccagatgtgggtgaacaacctgaggaggaggaagaggaagatgcacacagt gtcatggacgaggcggctggagaggaagagggcaccctggagtcggcctcagccttcacc accgcatgccgctcagtcaagaagaagattggccatgtccgccaaatctttacggttaaa aatgtgcgcaagcagttcaagaaaatcaagaagctgagcatcaaggagattatcaccagc tttttctccttcttctggatgcttttcaccggcttcttcaagggaatctacggcctcatc tttgggttcttccacgtcatctggtcctccatgtttggtggtggcctggttgagggagcc aagaacataaaggtgacggacatcctgggaaacatgcctgacccaactcagttcggtatc cacggagatgtgatcgaaggagagaaagtggaggccatagagtcaacaggaagcttagat gatgccatatcaccagcaggcgacctggcagaggtggacgcaatgttggagatgctgtcc aatcccaagagggaaggaggaaaacatattgagcttggcctgggtgatgtttccgagttg agtgcagagacgtccactactgatcaaaagaaagccgctgccaagcctgttgtaaccccc gagaacgaaccagagaaagcagacacagagaaccaggagaaggaggacaagccaaaggac gaggccaaggagccagtggcggaggagaagcccaagaccaaatcgagtcagcctaaaggg gcgacacccgccttcatgatgagtatcgttgctggtctggacgtcttaatgaccaagatt gtgaactacctggctcgtaacttctacaccctgcgtttcctggctctgtttgtgtgtttt gccatcaacttcattcttctcttctacaaggtcactgaacctgatgaagaaatcgatgag gaaagcacctgggatggggaagacgaggatgatgtggacacactcttcgacatggatgaa tttagcctgcaggagagcactggctacatgttaccaacgctgcgcttcctggctatattt cacactgtcatctcactcgtctgtctggttgggtactactgtctgaaggttcctttagtg gtgttcaagagagagaaggagattgccaggaagcttgaatttgacggtctctacatcacc gaacagccgtctgacgatgacatcaagggccagtgggatcgcctcgtcatcaacaccccg tctttccccagcaactactgggacaagtttatcaagcgcaaggtgatcaacaaatacggt gacctgtatggagctgaacgcatcgctgagctcttaggtctggataagagcgctctggac tttgacccaacagtggagactgtagagaaggaagcttccctgctctcctggctaagctcc attgatacaaagtaccacatctggaaaatgggcgtggttctgactgacaattactttctg tatctgatctggtacgccaccatgtccgtttttggacacttcaacaacttcttctttgct gcccatctgctggacatcgccatgggcttcaagacccttcgcactatcctgtcttctgtc actcacaacggcaagcagctcgtgctgactgtgggtctgctggccgtggtcgtctatctc tacaccgtggtggccttcaacttcttcagaaagttctacaataagagcgaggatgaagac gagcctgacatgaagtgtgacgatatgatgacgtgctatttgttccacatgtacgtgggt gtgagagctggaggtggtattggagacgagttggaggacccagctggagacccctatgag ctctaccgcatcctgtttgacatcactttcttcttctttgtcattgtcatcctgctggcc atcattcagggtttgatcattgatgcctttggtgagctgagagaccaacaggagcaggtg aaggaggacatggagaccaaatgcttcatctgtggcattgggaatgactactttgaccgg acgcctcacgggtttgaaacccacaccttacaagagcacaacctagctaactatctgttt ttccttatgtacctgattaacaaggacgagactgaacacacgggtcaggagtcgtatgtg tggaagatgtaccaggagagatgctgggacttcttccctactggagactgcttccgtaaa caatatgaggaccagttgggttaa

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