KEGG   Streptomyces avermitilis: SAVERM_1022
Entry
SAVERM_1022       CDS       T00126                                 
Symbol
crtE
Name
(GenBank) geranylgeranyl diphosphate synthase
  KO
K13787  geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
Organism
sma  Streptomyces avermitilis
Pathway
sma00900  Terpenoid backbone biosynthesis
sma00997  Biosynthesis of various other secondary metabolites
sma01100  Metabolic pathways
sma01110  Biosynthesis of secondary metabolites
Module
sma_M00364  C10-C20 isoprenoid biosynthesis, bacteria
Brite
KEGG Orthology (KO) [BR:sma00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    SAVERM_1022 (crtE)
  09110 Biosynthesis of other secondary metabolites
   00997 Biosynthesis of various other secondary metabolites
    SAVERM_1022 (crtE)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01006 Prenyltransferases [BR:sma01006]
    SAVERM_1022 (crtE)
Enzymes [BR:sma01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.1  dimethylallyltranstransferase
     SAVERM_1022 (crtE)
    2.5.1.10  (2E,6E)-farnesyl diphosphate synthase
     SAVERM_1022 (crtE)
    2.5.1.29  geranylgeranyl diphosphate synthase
     SAVERM_1022 (crtE)
Prenyltransferases [BR:sma01006]
 Terpene biosynthesis
  Prenyl diphosphate synthase
   SAVERM_1022 (crtE)
SSDB
Motif
Pfam: polyprenyl_synt
Other DBs
NCBI-ProteinID: BAC68732
UniProt: Q79ZL1
LinkDB
Position
1289024..1290265
AA seq 413 aa
MRRSKATDHQAAGPSPGPRDAFRPASVDEDVPAAVGRLLDRFLAERVARAAALDPVFAHD
IAERVARFTLDGGKRTRSQFVWWAHRACGGPAAGAEAALRVGAALELIQTCALVHDDVMD
GSRLRRGRPALHTDVSAQYADAVLPAPGTRFGEAAAILAGDLALAWADDVVADTDLAPDP
GRRVREVWSCLRMEMVAGQYLDIQGQATSSHSEARAMRAACLKSALYSVQRPLELGAALA
GADTATTQALCSAGRCVGLAFQLRDDLHDVFEEPRRTGKPSGGDIRAGKPTYLVAVARAR
AEAAGDRGALAVLRRSLGCADLSDADLARVRDVLVTTGARDTVEAEIDRLVAQGLRHMGA
ASLAPEGRRHLDALLRSAAGAPSVRRQAPDASRSENGMPVSLLLTATAEGASR
NT seq 1242 nt   +upstreamnt  +downstreamnt
atgcgccgcagcaaggcgaccgatcaccaggcggccggtccgtcaccgggcccgcgcgac
gcgttccggccggcctccgtcgacgaggacgtaccggccgccgtgggccgacttctcgac
cgcttcctggcggagcgcgtggcgcgggcggcggccctcgacccggtgttcgcccacgac
atcgccgagcgcgtggcgcggttcaccctggacggcggcaagcgcacccggtcccagttc
gtgtggtgggcgcaccgggcgtgcggcggaccggccgccggggcggaggcggccctgcgg
gtcggtgccgccctcgaactcatccagacgtgcgcgctggtgcacgacgacgtgatggac
ggctcccggctgcgccgcggccggcccgcgctgcacacggacgtgagtgcccagtacgcc
gacgccgtcctgcccgccccgggcacacgcttcggtgaggcggccgcgatcctcgccgga
gacctggctctcgcctgggcggacgacgtggtggcggacaccgacctggcaccggacccg
gggcgcagggtgcgcgaggtgtggagctgcctgcggatggaaatggtggccgggcagtac
ctggacatccagggccaggcgacctcgtcgcattccgaggcccgcgcgatgcgcgccgcc
tgcctcaagagcgcgctgtactccgtgcagcggccgctcgaactcggtgccgccctcgcc
ggggcggacaccgccacgactcaggcgttgtgctcggcgggccggtgcgtcggcttggcc
ttccagctccgcgacgacctccacgacgtcttcgaggaaccccggcgcaccggcaagccg
tcgggcggtgacatccgggcgggcaaacccacctacctcgtcgccgtggcgcgggcccgg
gccgaagcggccggcgaccgcggcgccctcgccgtactgcggcgctcgctcggttgcgcc
gatctgtccgacgcggacctcgcccgggtgcgggacgtcctggtcaccaccggcgcgcgt
gacacggtcgaggccgagatcgaccggctggtggcccagggcctgcgccacatgggcgcc
gcctcactcgcccccgagggacgacgccatctggacgcactgctccgttcagcggccggt
gcgccctcggtccgccggcaggcccctgacgcgtcccgctccgagaacgggatgcccgta
tcgctgctgctcaccgccacggccgagggggcctcccgatga

KEGG   Streptomyces avermitilis: SAVERM_1651
Entry
SAVERM_1651       CDS       T00126                                 
Symbol
hopB
Name
(GenBank) farnesyl diphosphate synthase
  KO
K13787  geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
Organism
sma  Streptomyces avermitilis
Pathway
sma00900  Terpenoid backbone biosynthesis
sma00997  Biosynthesis of various other secondary metabolites
sma01100  Metabolic pathways
sma01110  Biosynthesis of secondary metabolites
Module
sma_M00364  C10-C20 isoprenoid biosynthesis, bacteria
Brite
KEGG Orthology (KO) [BR:sma00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    SAVERM_1651 (hopB)
  09110 Biosynthesis of other secondary metabolites
   00997 Biosynthesis of various other secondary metabolites
    SAVERM_1651 (hopB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01006 Prenyltransferases [BR:sma01006]
    SAVERM_1651 (hopB)
Enzymes [BR:sma01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.1  dimethylallyltranstransferase
     SAVERM_1651 (hopB)
    2.5.1.10  (2E,6E)-farnesyl diphosphate synthase
     SAVERM_1651 (hopB)
    2.5.1.29  geranylgeranyl diphosphate synthase
     SAVERM_1651 (hopB)
Prenyltransferases [BR:sma01006]
 Terpene biosynthesis
  Prenyl diphosphate synthase
   SAVERM_1651 (hopB)
SSDB
Motif
Pfam: polyprenyl_synt SCP_3 PEHE
Other DBs
NCBI-ProteinID: BAC69362
UniProt: Q82MK9
LinkDB
Position
complement(2022306..2023436)
AA seq 376 aa
MTPDLHGTGPRTPRTATRGETVPTVPPAEKAADAVDVTALLERGRTLSTPVLRAAVDRLA
PPMDTVAAYHFGWIDAAGNPADGDGGKAVRPALAVLSAQAAGAAPEVGVPGAVAVELVHN
FSLLHDDLMDGDEQRRHRDTVWKVHGPAQAILVGDALFALANEILLELGTVEAGRATRRL
TTASRALIDGQAQDISYEHRERVTVEECLEMEGNKTGALLACACSIGAVLGGADDRTADT
LEKYGYHLGLAFQAVDDLLGIWGDPESTGKQTWSDLRQRKKSLPVVAALAAGGPASRRLG
ELLAEDAKSSDFENFSEEEFAARAALIEEAGGREWTAQEARRQHTIAIEALDTIEMPQQV
RAQLVALADFVVVRKR
NT seq 1131 nt   +upstreamnt  +downstreamnt
gtgacgcccgatctgcacgggactggtccccgcaccccccgtaccgcaacaagaggagag
actgtgcccactgtgcccccggccgagaaggctgccgacgcggtggacgtgaccgcgctc
ctggagcgcggccggaccctgtccaccccggtgctgcgcgcggccgtggaccgcctggca
ccgcccatggacaccgtcgccgcctaccacttcggctggatcgacgccgcgggcaacccc
gcggacggtgacggcggcaaggccgtacgccccgccctcgccgtgctctccgcgcaggcc
gccggtgccgcccccgaggtgggcgtcccgggcgcggtcgccgtcgaactggtgcacaac
ttctcgctgctgcacgacgacctgatggacggcgacgaacagcgccgccaccgcgacacc
gtctggaaggtgcacggccccgcccaggccatcctcgtcggcgacgccctcttcgcgctg
gccaacgagatcctcctggagctcggcacggtcgaggcgggccgcgccacccgccgcctc
accaccgccagccgcgccctgatcgacggccaggcgcaggacatctcctacgagcaccgc
gagcgggtcaccgtcgaggagtgcctggagatggagggcaacaagaccggcgcgctgctc
gcctgcgcctgctccatcggcgcggtcctcggcggcgcggacgaccgcaccgccgacacc
ctggagaagtacggctaccacctcggcctcgccttccaggccgtcgacgacctcctcggc
atctggggcgacccggagtccaccggcaagcagacctggagcgacctgcgccagcgcaag
aagtccctcccggtcgtggcggcgctcgccgcgggcggacccgcctcccggcggctcggc
gaactgctcgccgaggacgccaagagcagcgacttcgagaacttctccgaagaggagttc
gccgcgcgtgccgcgctcatcgaggaggcgggcggtcgcgagtggaccgcccaggaggcg
cggcgccagcacacgatcgccatcgaggccctggacacgatcgagatgccccagcaggtg
cgggcccagctcgtggcgctcgccgacttcgtcgtcgtacggaagagatga

KEGG   Streptomyces avermitilis: SAVERM_2997
Entry
SAVERM_2997       CDS       T00126                                 
Symbol
ptlB
Name
(GenBank) farnesyl diphosphate synthase
  KO
K13787  geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
Organism
sma  Streptomyces avermitilis
Pathway
sma00900  Terpenoid backbone biosynthesis
sma00997  Biosynthesis of various other secondary metabolites
sma01100  Metabolic pathways
sma01110  Biosynthesis of secondary metabolites
Module
sma_M00364  C10-C20 isoprenoid biosynthesis, bacteria
Brite
KEGG Orthology (KO) [BR:sma00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    SAVERM_2997 (ptlB)
  09110 Biosynthesis of other secondary metabolites
   00997 Biosynthesis of various other secondary metabolites
    SAVERM_2997 (ptlB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01006 Prenyltransferases [BR:sma01006]
    SAVERM_2997 (ptlB)
Enzymes [BR:sma01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.1  dimethylallyltranstransferase
     SAVERM_2997 (ptlB)
    2.5.1.10  (2E,6E)-farnesyl diphosphate synthase
     SAVERM_2997 (ptlB)
    2.5.1.29  geranylgeranyl diphosphate synthase
     SAVERM_2997 (ptlB)
Prenyltransferases [BR:sma01006]
 Terpene biosynthesis
  Prenyl diphosphate synthase
   SAVERM_2997 (ptlB)
SSDB
Motif
Pfam: polyprenyl_synt
Other DBs
NCBI-ProteinID: BAC70708
UniProt: Q82IY5
LinkDB
Position
3753107..3754120
AA seq 337 aa
MTVTPESLHRSRDAITPALRTALHLLDEETRHQAAYHLGWIEADGTPADGGGGKAVRPAL
ALLSAQAAGAPAETGLPGAVAVELVHNFSLLHDDLMDGDEERRHRRTVWTLWGASGAILT
GDALLALAQEVLLDCGLPTGAAAARLLARTTRDLIRGQVQDVAFERRAHVPIEECVDMAA
GKTGALLSASAAIGAVLAGAPVTTVDALALYGQQVGLAFQLTDDVLGIWGDPAVTGKSVH
SDLRARKKSLPVTYALNQGGTVSVELATWLSAPGEPDEAELRRAADLVAAAGGRDWATAE
AARRMALGEAALRGVDLDAAARDELIALGHFVVDREV
NT seq 1014 nt   +upstreamnt  +downstreamnt
atgaccgtgaccccggaaagtctgcaccgcagccgcgacgcgatcacaccggcgttgcgc
accgcgctccacctgctcgacgaggagacccgccatcaggcggcgtaccacctcggctgg
atcgaggccgacggcaccccggcggacggcggcggaggcaaggccgtacggcccgcgctc
gcgctgctgtcggcgcaggcggccggcgcaccggcggaaaccggcctgcccggtgcggtg
gccgtcgaactggtgcacaacttctcgttgctgcacgacgacctgatggacggcgacgag
gagcgtcggcatcgacgtacggtctggacgctgtggggcgcctcgggcgcgatcctcacc
ggtgacgcgctgctggcgctcgcgcaggaggtgctgctcgactgcgggctgcccacgggg
gcggccgcggcgcggctgctcgcccgcaccacccgcgacctcatccgcgggcaggtgcag
gacgtggcgttcgagcggcgggcccatgtgccgatcgaggagtgcgtcgacatggcggcc
ggcaagaccggcgcgctgctgtcggccagcgccgcgatcggtgccgtactggccggcgcg
ccggtgaccaccgtcgacgccctggcgctctacgggcagcaggtgggcctcgccttccag
ctgaccgacgacgtcctcggcatctggggcgacccggctgtcaccggcaagtcggtccac
tccgacctgcgggcccgcaagaagtcgctgccggtcacgtacgcgctcaaccagggcggg
accgtgagtgtcgagctggccacctggctctccgcaccaggcgagcccgacgaggcagag
ctgcgccgggcggccgacctggtggcggcggccggcggccgcgactgggccaccgccgag
gcggcccggcgcatggcgctcggggaggccgcgctgcgcggcgtcgacctggacgccgcg
gcgcgcgacgagctcatcgccctcggacacttcgtcgtcgaccgggaggtgtga

KEGG   Streptomyces avermitilis: SAVERM_3006
Entry
SAVERM_3006       CDS       T00126                                 
Symbol
idsB
Name
(GenBank) putative polyprenyl diphosphate synthase
  KO
K13787  geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
Organism
sma  Streptomyces avermitilis
Pathway
sma00900  Terpenoid backbone biosynthesis
sma00997  Biosynthesis of various other secondary metabolites
sma01100  Metabolic pathways
sma01110  Biosynthesis of secondary metabolites
Module
sma_M00364  C10-C20 isoprenoid biosynthesis, bacteria
Brite
KEGG Orthology (KO) [BR:sma00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    SAVERM_3006 (idsB)
  09110 Biosynthesis of other secondary metabolites
   00997 Biosynthesis of various other secondary metabolites
    SAVERM_3006 (idsB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01006 Prenyltransferases [BR:sma01006]
    SAVERM_3006 (idsB)
Enzymes [BR:sma01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.1  dimethylallyltranstransferase
     SAVERM_3006 (idsB)
    2.5.1.10  (2E,6E)-farnesyl diphosphate synthase
     SAVERM_3006 (idsB)
    2.5.1.29  geranylgeranyl diphosphate synthase
     SAVERM_3006 (idsB)
Prenyltransferases [BR:sma01006]
 Terpene biosynthesis
  Prenyl diphosphate synthase
   SAVERM_3006 (idsB)
SSDB
Motif
Pfam: polyprenyl_synt
Other DBs
NCBI-ProteinID: BAC70717
UniProt: Q82IX6
LinkDB
Position
complement(3760742..3761926)
AA seq 394 aa
MGEFLTEAKQSPAEVLERRSPAGPAGRRGPLPAPSTGRQAPAASPPTDPQGPAAQLDGQE
AAGILERARASVDPELRRAVDSLPGSMRRIALHHFGWEHADGTPAAGNAGKAIRPALVLA
AVRALGGPQSSAVRAAAAVELIHNFTLLHDDVMDRDTTRRHRPTAWTVFGDADAILAGDA
LQALAHRLLAEDPHPASAAAAARLAACVIELCAGQHADTAMERRGPGEVTLDECLAMAEA
KTGALLGCACALGALYAGAEEEDVEALDAFGREAGLAFQLIDDVIGIWGDPSRTGKPAGA
DLMARKKSLPVVAALAAGTPAAAELAELYAVPHQEGELERTVLAVERAGGRDWAQQQAAD
RMARAMHELSRAIPDPEAAGGLLALAEFVTRRSN
NT seq 1185 nt   +upstreamnt  +downstreamnt
atgggtgagttcctgacggaggcgaagcagagcccggccgaggtgctcgaaaggcggagc
cccgcgggccccgccggccggcgaggcccgctcccggctccgtccaccgggcggcaggcg
ccggccgcgagtccgcccaccgatccgcagggcccggcggcccagctcgacgggcaggaa
gccgcggggatcctggagcgtgcccgggcctcggtcgaccccgagctgcgccgggccgtc
gactcgctgccggggtccatgcgccggatcgcgctccaccacttcggctgggagcacgcg
gacggcaccccggcggcaggcaacgcgggcaaggcgatccgccccgcgctcgtgctggcc
gcggtccgggcgctcggcggaccgcagtcctccgccgttcgggccgccgcggcggtggag
ctgatccacaacttcaccctgctgcacgacgacgtcatggaccgggacaccacccgcagg
caccgccccaccgcgtggaccgtgttcggcgacgccgacgcgatcctcgccggggacgca
cttcaggccctggcccaccggctgctcgccgaggacccgcacccggcgtccgcggcggcc
gccgcccggctcgcggcctgtgtcatcgaactgtgcgcggggcagcacgcggacacggcg
atggagcggcgcggcccgggtgaggtcaccctcgacgagtgcctcgccatggccgaggcc
aagacgggcgcgctgctcggctgcgcctgtgcgctgggggcgttgtacgcgggggcggag
gaggaggacgtcgaggcgctggacgcgttcggccgggaggccgggctcgccttccagctc
atcgacgacgtgatcgggatctggggggacccgagccgaaccggcaagccggccggggcg
gacctgatggcccgcaagaagtccctgcccgtggtggccgcgctcgccgcgggcactccg
gcggcggcggaactcgccgagctgtacgcggttccgcaccaggaaggggagctggagcgc
acggtcctggccgtcgagcgggccggcggccgcgactgggcccagcagcaggccgccgac
cggatggcccgggcgatgcacgagctgtcccgggcgattccggacccggaggcggcgggc
ggcctgctcgccctcgccgagttcgtgacccggcgcagcaactga

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