Scophthalmus maximus (turbot): 118289762 Help Entry 118289762         CDS       T09850                                  Symbol ryr3 Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism smau  Scophthalmus maximus (turbot) Pathway smau04020   Calcium signaling pathway smau04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:smau00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     118289762 (ryr3)    04020 Calcium signaling pathway     118289762 (ryr3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:smau04040]     118289762 (ryr3) Ion channels [BR:smau04040]  Voltage-gated cation channels   Ryanodine receptor    118289762 (ryr3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_8 YjfB_motility Motif Other DBs NCBI-GeneID:  118289762 NCBI-ProteinID:  XP_035472649 LinkDB All DBs Position 18:14876964..14968527 Genome browser AA seq 4854 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQSVANIQKEHRKFCLAVEGLGNRLCYLESTSEAKSVPP DLCICNFVLEQSLSVRALQEMLANTGQNSEGSADHDKWAGQGGGHRTLLYGHAILLRHSF SGMYLTCLKTSRSLTDKLSFDVGLQEDSIGESCWWTIHPASKQRSEGEKVRIGDDLILVS VSTERYLHLSISNGNIQVDASFMQTLWNVQPTCSSGNMAVGFLVGGHVMRLCHGHDESLT IPGADKSEEEQRIVNYEAGKGASRARSLWRLEPLRISWSGSHIRWGQAFRLRHLSTGHYL ALTEDRGLVLQDREKCDTTATAFCFRASKEKGDSGPKRDIDGMGAPEIKYGDSVCFIMHV ATGLWLSYLAPDAKSSRLGPLKRRACLHSEGHMDDGLTLQRCQHEESRAARIIRNSTFLF TNFIKALDSTADGESMAVGGYVEEVLQTLNDLIEYFKQPDSELEHEEKQCLLRSLIKRQD LFKEEGMLALVSKCIDRMNLYDSAAHFGEMAGEEAGAAWKDILNLLYELLASLIRGNRNN CTQFSRNLDWLVSKLERLESSSGILEVLHCILVESPEALNIIQRGHIKSIISLLYKHGRN HKILDVLCSLCVCNGVAVRANQNLICDNLLPKRDLLLQTRLVNDVQSMRPNIFLGVADGS AQYKKWYFELVIDQVDHFVTGEPTHLRVGWANTKGYAPYPGGGEGWGGNGVGDDLYSYSF DGLHLWSGRIPRAVASINMHLLNSDDVVSCCLDLGAPSMSFRINGQPVQGMFEDFNTDGF FFPVVSFSAGVKVRFLLGGRHGDFKFLPPAGYSPCYEALLPKEKMHVEPVKDYKRDHDGI RNLLGTTKFLSQASFIPTPVDTTQIILPPHLDNVRDKLAENIHELWGMNKIELGWTYGKV RDDNKRQHPCLVDFAKLPETERNYNLQMSSETLKTLLALGCHVAQVNVHAEDDLKKVKLP KDYMMSNGYKPAPLDLSDVKLTAGQEVLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKSR RNPRLVPYALLDERTKKSNRDSLREAIRTVVGYGYDIDPPDQEVVHLVDDQSIDTIRFFR VEQTYAVKTGKWYFEYEALSGGDMRVGWARPACRPDVELGTDDQAFVFDGYKGRRMHAGS RYFGQPWKTGDVVGCMINMEDKSMIFTLNGELLITNKGSELCFTDFETEEGFIPVCSLGM SQVGRMNLGKDASSFKYYTMCGLQEGFEPFAVNMNRDITMWFSKRLPTFVNIPEDHMHIE VTRIDGTVDSPPCLKVTHKTFGTQNSNNDMVYCRMSMPVEFHAADSFLDESLKLSHTPKE DGTVDYGSITTYYHSVRVFAGQDPASVWVGWVTPDYHYYSKNFGLDKTRTVTVTLGDERG RVHESVQRSNCYMVCGADAVGPSASSRNNSDLEIGCLIDLATGLVSFTANGKELPTTYQV EPNTKLFPAVFVRPTSANLFQFEFVKIQDAMPLSSAIFKSEHRNPVPQCPPRLDVQTIVA VLWARMPNIFLSVETARVSERHGWVIQCLEPLQMMAVHIPEENRCLDILELSEHDDLKKF HYHTLKLYCALCALGNTRVAHALCSHMDQSQLLYTIDNQYLSGMLREGFYNVLISIHLET AKEARLMMNNEFIIPVTEETRSIKLFPDESKRHSLPGVGLSTSLTPRVNFSPVGIINTQR HQYLQSPQIPLGILKEKAISMLTEAVQGGGLHIRDPVGGSVKYQFVPILKLIGTLLIMGV LTSEEVRLILLLIDPNVFGEDKEGEEGKADDVAGEKEEVSKNEEKAVEAGEEETKESKPT AKGLLEKSLPESVKRQMCELLHYFCDCELKHRIEAIASFSDSYVSKLQYNQKFRYNELML AFNMSAAVTAKKTKEFRSPPHEQINILLNFSAGEDCPCPEEIQEELNSFHEELRLHCGIP VEEGEGEQDTSIKGRLLALVYKIKGPPQKTEEEPAETEQAAPTNLKELISQTITSWAQES HIQDPELVRVMFSLLRRQYDGIGELLRAMKKSYTISAASVQDAITLLASLGQIRSLLSVR MGKEEEKLMIDGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGGDKSQEIAFPKMV ASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASEAMRGSTPLDVAASSVMDNNGL ALALEEPDLEKVVTYLAGCGLQSCAMLVAKGYPDLGWNPIEGERYLSFLRFVVFCNGESV EENANVVVKLLIRRPECFGPALRGEGGQGLLAAMKEAIKISDDPALDLPKTPAVVTTGSG EEEGEIIHMGNAIMSFYSALIDLLGRCAPEMHLINAGKGEALRIRAILRSLVPTTDLVGI ISIPLKMPVVNKDGTVTEPDMSACFCPDHKAPMVLFLDRVYGIEDQSFLLQMLEVGFLPD LRASASLDTEVLSTTETALAMNRYIGSALLPLLTRCAALFASTEHYAQLIDSTLQTIYRL SKGRSLTKAQRDAIEDCLLAICKHLRPSMMQQLLRRLVFDVPMLTEYCKIPLRLLTNHYE QNWKYYCLPSGMGIFGTASEEELLLTKKLFWGIFDSLSQKKYDAELFKMAKSCLCAIAGA LPPDFVDVSLGATLEKQASVDAQGNFDPKPINTANISLPEKLEYIANKYAEHSHDKWSSE KVSAGWKHGDIMDEQTKTHPLLKPYKSLSEKERETYRWPVKESLKSMLAMSWDIERTKEG EAMFQQRESEKQQKISETEVNGFCPAPMDLHNATLSRELQGMVEVVAENYHNIWAKKKKT ELISKGGGTHPLLVPYDTLTAKEKYRDREKAQELLKFLQISGYAITRGLKDMEQESSMEK RFSFKFLKRMLKYIDSAQEFIAHLEAMATSGKTDKSPHDQEIKFFAKVLLPLTDQTFKNH CLYFLSTPNQNLSSCGCASNKEKEMVTSLFCKLAALVRHRISLFGSDSAMMVSCLHILTH SLDTRTVMKSGSELVKAGFRTFFENAAEDLEKLLEMLKLGKFMQSRAQMKSVSQSINYVT VALLPILTALFEHITTYEFGLDLLLDDMQLSCYRILTCFYSLGTGKNVFVERHLPALGES LATLVAAMPVAFLEPHLNAHNPLSVFNTKTPRERAILSMPDTVEEMCPEMPRLDRLLKDV NEVSGSGARYSDMPQVIEVILPMLCNYLSYWWEKGLENSPPEAQCCTMVTSEHLSMILGN ILRILNNNLGIDDAPWMKRIAVYSQPIICKAGADLLRTHFLPTLDKLKKKTVKVVAEEEL LKADSKGDNQEAELLILDEFAVLCRDLYAFYPMLIGYVDINRSRWLKEPDAYSTELFRMV AEIFILWCKSHNFKREEQNFVVQNEINNLGFLTGEGKTKMCKSGGDQERKHKRRRGEYYS IQTSLIVAALKKMLPIGLNMCTPGDQELISLAKIRYSLKDTDDEVKEHLRQNLHLQDKSD DPAVQWQLDLYKDVVVKSEEPANPEHTVDRVQSISAAVFHLEQVEQPLRNKKCVWHKLLS KQRKRAVVACFRMAPLYNLPRHRAINFFIPAYQRLWIEAEEYSFEEKLVQDLAKTPMKIV EEEEEEVADIQPDPLHQLILHFSHNALTERSHLEQDPLYIAYADMMAKSCAEDEEEEEEE GKEKTFEEKEMEKQKILYQQARLHARGAAEMVLQMISASKGRLGPMVTCTLKLGISILNG GNVKVQQKMLNYLKEKRDAGFFKSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGSIHT KRGSKVLQNDEFTKDLFRFLQLLCEGHNGDFQNFLRTQTGNTTTVNIIISTVDYLLRLQE SISDFYWYYSGKDVIDETGKINFSKALFVAKQIFNSLTEYIQGPCIGNQQSLAHSRLWDA VVGFLHVFANMQMKLSQDASQIELLKELMDLQKDMVVMLLSLLEGNVVHGTIGKQMVDTL VESSNNVEMILKFFDMFLKLKDLTTSENFREYDPECKGIISKKEFQKSMESQKQYSQSEI DFLLSCAEADENDMFNYKEFVGRFHEPAKDIGFNVAVLLTNLSEHMPHDSRLATFLDLAE SVLSYFEPYLGRIEIMGSAKRIERIYFEISESSREQWEKPQVKESKRQFIFDVVNEGGES EKMEMFVNFCEDTIFEMQLASQISEPDVVEQPEEEDDEDGHSILEELAAEEEGAAESASA FSTACCSVKKKFAQVRQKCSLKNVRKQFRKVMKLSIKEIITGVFSFFWMLFTGFFKGIYS LIFGFFHVIWSSMFGGGLVEGAKNIKVTDILGNMPDPTQFGIHLDVVEGEKVEAIESSGS LDITMAPVGEIAEVDMMMEILTGPKREGGKHVELGLGDVSELSAETSTADQKKKAADKPF ETPESEPEKADTENQEKEDKPKKEEAAKEPVTEEKPKTRTNQPKEAAPAFMSTVFAALDV FTNKMLNYLARNFYNLRFLALFVCFAINFILLFYKVTGEVDEEVEDESSWTEDEEADDEN TLFDMDEFVLQESSGYMLPALRFLAIFHTVISLVCLVGYYCLKVPLVVFKREKEIARKLE FDGLYITEQPSDEDIKGQWDRLVINTPSFPSNYWDKFIKRKVINKYGDMYGAERIAELLG LDKSALDFDPTVETVEKEASLLSWLSSIDTKYHIWKMGVVLTDNSFLYLIWYATISIFGH FNNFFFAAHLLDIAMGIKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFY NKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDELEDPAGDPYELYRILFDITFFFF VIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDRTPHGFETHTLQEH NLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPTGDCFRKQYEDQLG NT seq 14565 nt NT seq  +upstreamnt  +downstreamnt atggctgagggcggagaaggggaagatgagatccagttcttgagaactgacgatgaggtg gtgctccagagcgtggccaacatccagaaggagcatcgcaagttctgcctggccgtcgag ggacttggaaaccgtctatgttatctggaatccacttcagaagctaagtctgttcctcca gacctgtgcatttgtaactttgtgttggagcagtccctgtcagtgcgggccctgcaggag atgctggctaacactgggcagaacagcgaagggagtgccgaccatgacaaatgggcgggt cagggtggcggtcaccggaccctgctctacggtcatgccatcctcctacgccactccttc agtggtatgtacttgacctgtttgaagacgtcaaggtctctgacagacaagctgtcgttt gatgtcgggctacaagaagattcaataggagaatcctgttggtggaccatccaccctgcg tccaagcagagatccgagggagagaaagtccgcatcggagacgacctgattcttgtcagc gtgtcaacggagagatacctgcacctctctatctccaatggcaatatccaggttgatgcc tccttcatgcaaactctgtggaacgtccagcccacctgctcgtccggcaacatggccgta ggttttttggtcggtggacacgtgatgcgtctttgtcacgggcatgacgagagcttgacc atccctggagcagacaaaagtgaggaggagcagaggatagtcaactatgaggcgggtaag ggagcgtcgagggcccgctcactgtggagactggagcctctcaggatcagctggagcggc agccacattcggtggggccaggccttcaggctacgtcacctctccactggccattacctg gccctgaccgaggaccgtggactggtcctgcaggacagggagaagtgcgacaccacggcc accgccttctgcttcagggcctccaaggaaaagggtgactctggcccaaagagggacatt gacggcatgggagcgccagagatcaagtacggagactctgtctgcttcatcatgcatgtg gcgacgggtctgtggctgtcttacctggcgcctgatgccaaatcgtctcgcctaggaccc ctgaaaagacgggcctgcctacattctgagggccacatggacgatgggctgaccctgcag cgctgtcaacacgaggagtcccgtgccgcacgcatcatccgcaacagcacgtttctcttt accaacttcatcaaggctttggacagcactgcggacggcgagtccatggcggtaggcggg tacgtcgaagaggtgctgcagacgctgaacgacctgatcgagtacttcaaacaacccgac tcggagttggagcacgaggagaaacagtgtcttctccggtcgctcatcaagcgtcaagat ctcttcaaagaggagggtatgcttgccctcgtgtccaaatgcatcgacagaatgaacctg tatgacagcgctgcccactttggagagatggctggcgaggaggcgggcgccgcatggaag gacatcctcaaccttctttatgagctcttggcctcactgattcgtgggaacaggaacaac tgcacccagttttcccgtaacttggactggttggtcagcaaactggagcgactggaatct tcatcagggatcctggaagtcctccactgcattttggtagaaagcccggaggctctgaac atcatccagagagggcacattaaatccatcatctctttgctgtataaacatggacgcaac cacaagatcctggatgtcttgtgttccctctgtgtttgtaatggagtggcagtgagagcc aatcagaatctgatctgtgacaaccttcttcccaaaagggacctgctgcttcagactcga ctggtcaatgatgttcagagtatgagaccaaatatcttccttggcgtggccgacggctca gctcagtacaagaagtggtatttcgagctggtgatcgaccaggttgaccactttgtcact ggagagccgacccacctgagggtgggctgggccaacactaaaggctacgctccgtatcct ggtggaggagagggatggggaggcaacggcgtcggggatgacctgtactcctacagcttt gatggacttcatctttggtcaggccgaatcccgagggctgtggcctccatcaacatgcac ctgctgaactcggacgatgtggtcagctgctgtctggatctgggcgcccccagcatgtcc ttcaggatcaacgggcagcccgtccagggcatgttcgaggacttcaatacagatggattc ttcttccctgtcgtcagcttctctgcaggtgtcaaggtgcgtttcttgttgggcggacgc cacggagatttcaagttcctgccacccgctggttactctccgtgctacgaggcgctgttg ccaaaagagaaaatgcatgtggagcctgtgaaggattacaaaagggaccacgatgggatc cgtaatctgctgggaaccaccaagttcctctctcaggcctccttcatccccactcctgtg gacaccacccagattattcttccccctcacctggacaacgtccgggacaagctggcagaa aacatccacgagctgtgggggatgaacaagattgaactgggctggacctatggcaaggtc cgtgatgacaacaagaggcagcacccttgcctcgtggattttgccaagctgcctgaaacg gaaagaaactacaacctgcagatgtccagtgaaacgctcaagacccttttggcactggga tgccacgttgcccaggtcaatgttcacgctgaggacgatctgaagaaagtgaaacttcca aaagactacatgatgtctaatggatacaagcctgcgccactggacctctctgatgtgaaa ctgactgcaggtcaggaggttctagttgataaactggccgagaacgcacacaacgtgtgg gccaaagacagaattaaacaaggatggacctatggcatccagcaggatttgaagagcagg cgtaatcctcgcctggtgccgtatgctttactggatgaacgcacaaagaaatcaaacaga gacagtctgagagaggccatcaggaccgtggttggatacggttatgacatcgacccccca gaccaggaggttgtccacttggtggatgatcagagcatcgacaccattcgcttcttccgt gtggagcagacatacgcagtgaaaaccgggaagtggtactttgagtatgaggccctgagc ggaggtgatatgagggttggctgggcccgaccggcctgcagacccgacgtggagctggga acagacgaccaagcctttgttttcgatggatacaagggtcgtcgtatgcacgcaggcagc cgctactttggacaaccctggaaaacgggcgacgtggtcggttgcatgatcaacatggag gacaaatccatgattttcacgctgaacggagagctcctgatcaccaacaagggctctgaa ctttgcttcactgactttgaaacggaggagggtttcatccctgtgtgcagcctgggaatg tcacaggtcggccgtatgaacctgggcaaggacgccagcagttttaagtactacaccatg tgtggtctccaggaaggctttgagccctttgccgtcaatatgaacagagacatcaccatg tggttcagcaagcgcctgcccacctttgtcaacatacctgaggaccacatgcatattgag gtgacgaggatcgacggaacggtggacagtcccccctgcctcaaggtcacccacaagacg ttcggcacacagaacagcaacaacgacatggtgtactgtagaatgagcatgcctgtcgag ttccatgctgcagactcgtttctggatgaatcgctgaaactcagccacactccaaaagaa gacggaactgttgactatggaagcatcacaacttactaccactcagtgagagtgtttgct ggacaggaccctgcctcagtgtgggtgggctgggtcacaccagactatcactactacagc aagaacttcggcctcgacaagacgcgaacagtcaccgtcaccctgggagatgagaggggc cgagtccacgaaagtgtccagaggagtaactgctacatggtgtgcggagcagacgctgtc ggcccgtcggcctccagccgcaacaactctgacctggagatcggctgtctgattgacctg gccactggccttgtctccttcactgccaacggaaaggagctgcccacaacatatcaggtg gagccaaatacaaagctcttcccagctgtgttcgtacgccccaccagtgcaaacctcttc cagtttgaatttgtcaagatccaggatgccatgccactgtcatccgccatattcaagagt gagcacaggaacccggtgccccagtgcccgccgcggctggatgtgcagaccatcgtggcc gtgctgtgggcgcggatgccaaacatcttcctcagtgtggagacggcccgggtcagcgag aggcacggctgggtgatccagtgtctggagccactgcagatgatggctgttcacatcccc gaggagaacaggtgtctggacatcctggagttgtctgagcatgatgacctgaagaagttc cattaccacacgctgaagctgtactgtgccctctgtgccctcggaaacacccgtgtggct cacgccctctgcagccacatggatcagtcacagctcctctacaccatcgacaaccagtac ctctctggcatgttgagagagggattctataacgtcctcatcagcatccatcttgagaca gcgaaggaggctcgcctaatgatgaataacgagttcatcatccctgtgacggaggagaca cgctccatcaaactgttcccagatgagtctaagcggcactcgctgcccggcgtgggcctg agcacctccctcacgcctcgggtcaacttctccccagtcggcatcatcaacacacaacgc caccagtacctccaaagcccccagatccctcttggcatcctgaaagagaaggccatcagc atgctcaccgaggctgtgcagggcggcggcctacacatccgagacccagtgggtggaagc gtcaagtaccagttcgtcccgatcctgaagctgattggaacgctgttaatcatgggagtc ctaaccagcgaggaagtgaggctgattctcctcctgattgaccccaacgtgtttggagag gacaaggagggtgaggaggggaaggcagacgatgtggcaggggagaaggaggaagtgagc aagaatgaggagaaggccgtggaggcgggagaagaggagaccaaggagagtaaaccaacg gctaaaggtctgctggagaagtcactgcccgagtctgtcaaacgccagatgtgtgagctg ctgcactacttctgtgactgcgagctgaagcaccgcatcgaggccattgcctcgttctcc gacagctacgtgtcgaagctgcagtacaatcagaagttccgttacaatgagctgatgctg gcgttcaacatgtccgctgccgtcaccgccaagaagaccaaagagttccgctctccgcca catgagcagatcaacattctgttgaatttcagtgcaggtgaggactgcccctgtcccgaa gagatccaggaagaactcaactccttccatgaagaattgcgactgcactgtggaattcca gtggaggagggagagggagagcaggacacgtcgataaaaggccgtctccttgctctggtt tacaagatcaagggtccacctcagaagacagaggaggaaccggcagagacggaacaggct gctcccaccaacctgaaggagctcatctcacagaccataaccagctgggcccaggagtct cacatccaggacccagagctggtcagagtgatgttcagcctgctgaggcggcagtatgac ggcatcggggaattgctccgggccatgaagaaatcctacaccatcagtgctgcatccgtg caggatgccatcaccctgttggcatctttgggtcaaatcaggtctctgctgtcagtgcgt atgggcaaagaggaggaaaaactcatgattgatggactcggcgacatcatgaacaacaag gttttctaccaacaccccaacctgatgagagtgctgggcatgcatgagactgtcatggag gtcatggtcaatgtgctgggaggagacaagtcacaggagattgccttccccaagatggtg gccagctgttgccgtttcttgtgctacttctgtcgcatcagtcgccaaaaccagaaagcc atgttcgaccacctgagctacctgctggagaacagcagcgttggactggcctctgaagct atgcggggctccactccgctggatgtcgcagcgtcttcagtgatggataacaacggcctg gctctggccctggaggagcccgatctggagaaggtggtgacatacctggcaggttgtggt cttcagagctgtgctatgttggttgccaagggatacccagacctcggctggaaccccata gagggcgagcgttacctgtccttcctgaggttcgttgtcttctgcaacggtgaaagtgtg gaggaaaatgccaatgtggtggtaaagctgctgatcagacgcccggagtgtttcggcccc gccctgaggggagagggaggccagggtctgctggctgccatgaaggaggccattaagatc tctgatgatcctgccctggacctgccaaagacccctgctgtagtcactactgggtctggt gaagaagaaggagaaattatccacatgggcaacgccatcatgtccttctactcggctctt attgatctgctgggacgttgcgctccagagatgcatcttatcaatgctggtaaaggtgag gcgctgcgtatcagagccatcctgcgttctctggttcccactacagacctggtgggcatc atcagcatccccctcaaaatgcctgtggttaataaagatggcacagtgacagagccagac atgtcggcctgtttctgtccggaccacaaggcccccatggtgctcttcctcgaccgagtg tacggcatcgaggaccagagcttcctgctccagatgttggaggttggcttcctgcctgac ctgcgagcctcagcatctctggatacggaggtgttgagcaccactgagacagcgttggcc atgaacagatacatcggctcggctctgctgcctctgctgacccgctgcgccgcgctcttt gccagcacagagcactacgctcagctgatcgactccacgctgcagaccatctaccggctg tccaaaggccgctcgctcaccaaagcccaaagggacgccatcgaggactgtctgctggcc atctgcaagcacctgcgtccctccatgatgcagcagctgcttagacggctggtgtttgat gttcccatgctcactgaatactgcaagatacctctgcggctgctgaccaaccactatgag cagaactggaagtactactgcctgccgtctggtatgggcatctttggcacagcctctgag gaggagctgctcctcaccaagaaactattctggggaatctttgactccctttctcagaag aaatatgatgctgaacttttcaaaatggccaagtcatgcctgtgtgccatcgccggagcc ctgcctcctgactttgtggatgtcagtcttggggcaacactggagaaacaggcatcagtg gatgcacaaggcaactttgaccccaaacccatcaacactgccaacatctcccttcctgaa aaacttgagtacattgccaacaaatatgcagagcattcccatgacaagtggtcttcggag aaggtatcagcgggctggaaacatggagacattatggacgagcagactaaaacacatcca ctgctgaaaccttacaaatcactgagtgagaaggagagagaaacataccgctggccagtg aaggagtcgttgaagagcatgttggctatgagctgggacattgagaggaccaaggaggga gaagccatgttccagcaacgagagagcgaaaaacaacaaaagatctcagagactgaggtt aatggattctgtcctgctccgatggacctgcataatgccactttgtctagagagttacag ggcatggtggaggtggttgcggaaaattaccacaacatctgggccaagaagaagaaaact gagctcattagcaaaggaggagggacccatcccctgctggttccctatgacaccctgaca gctaaagagaagtacagagatcgagagaaggcccaggagctcctcaagtttcttcagatc agtggatatgctatcacaagaggtctgaaggatatggagcaggagtcgtccatggagaaa cgcttttccttcaagttcctcaagaggatgctaaaatatatcgactctgcccaggaattt attgctcacctggaggcgatggccaccagtgggaagacagacaaatcacctcatgaccag gagattaaattctttgccaaggttttgcttcctctgacagatcaaacctttaagaaccac tgcctctacttcctgtccacacccaaccagaacctgagcagctgtggctgtgcctccaac aaagagaaggagatggtcaccagcctgttctgtaagctggcagcccttgtcagacatagg atttctctctttggcagtgactcagcaatgatggtgagctgtctgcacatcctcactcac tcactcgacaccagaacagtgatgaaatctggctcggagctggtcaaagccgggttccgg actttcttcgagaacgcagcagaggacctggagaagctgctggagatgctgaaactgggg aagttcatgcagtcccgtgcccagatgaagagcgtcagccagagcatcaactacgtgact gtggcactgctgcccatcctcactgcccttttcgaacacatcaccacatacgagtttgga ctggacctgctgttggatgacatgcagctgtcctgctacagaatcctgacgtgtttctac tctctgggaacaggaaagaacgtctttgtggagaggcatcttcctgcactgggggagagt ctggcaaccttggtggcagccatgcctgtagctttcctggagccccaccttaacgcccac aaccctctctctgtcttcaacaccaagacaccccgagagagagccattctcagtatgccg gacacagtggaggagatgtgtccagagatgcctcgtcttgatagactcctgaaagatgtc aatgaggtctccgggtctggtgctcgatacagcgacatgccacaggtcattgaggtgatc ctccccatgctgtgtaactacctctcctactggtgggagaaaggtctggagaactctcct ccagaggcccagtgctgcaccatggtgacctctgaacacctcagcatgatcctgggaaat atcctcaggattctcaacaacaacctgggcattgacgacgcgccctggatgaagaggatt gcagtctactctcagccaatcatctgcaaggctggagcagatctgctgagaacccacttc ctgcccacactggacaaattaaagaagaagacggtgaaggtcgtggctgaggaggagctg ctgaaggccgacagtaaaggtgacaaccaggaggccgagctgctcatcctggatgagttt gctgtgctctgcagggacctctacgccttctaccccatgctcatcggctacgtggatatc aacaggtctcggtggttgaaagagcctgacgcctactccactgagctcttcaggatggtg gctgagatctttatcctctggtgcaagtcccataactttaagcgtgaggagcaaaacttt gtggttcagaatgagatcaacaatttgggcttcctgactggagaaggcaagacgaagatg tgcaagtcaggtggggaccaggagaggaaacacaagcgtcgtcgtggtgaatactactcc atccagacctcactgatcgtcgctgccttgaagaagatgctgcccatcggcctcaacatg tgcaccccgggcgaccaggagctcatctctttggccaagatacgctacagcctgaaagac acagatgacgaggtgaaggagcacttgcgtcagaatctccatctccaggacaagtctgac gacccagcggtccagtggcagttggatctgtacaaggacgtggtggtgaagagcgaggaa ccagcaaacccagaacacacggtggaccgagtccagagcatctctgctgccgttttccac ctggagcaggtcgagcagcctctgaggaacaagaagtgtgtgtggcacaagctgctgtcc aaacagcgtaaacgtgctgtggtggcttgtttccgtatggctccactgtataatctaccc aggcatcgcgctatcaacttcttcatcccggcctatcagagactttggatagaggcagag gagtactcctttgaggagaagctagttcaggatctggcaaaaacccccatgaagattgtg gaggaggaggaagaggaggtggctgacatccagcccgaccctcttcatcagctcattctc cacttcagccacaacgcactgacagagagaagtcacttggaacaagatcctttgtatatt gcatatgcagacatgatggcaaagagctgtgcggaggacgaggaggaggaagaggaggaa gggaaagaaaagacatttgaggaaaaggagatggagaagcagaagatcctgtatcagcag gcgaggctgcatgcgcgtggggcagcggagatggtgttgcagatgatcagcgccagtaaa ggtcgtcttggccccatggtgacctgcaccctcaaactgggaatctccatcctaaatgga ggcaacgtgaaagttcagcagaaaatgctcaattacctgaaagagaaaagagatgcagga tttttcaagagtctctcaggattgatgcagtcatgcagtgtcctggacttgaatgcattt gagaggcagaacaaagcagaaggtcttggcatggtgacagaggaagggtcaatccacact aagcggggctccaaggtgcttcagaatgatgagtttactaaagatctgttccggtttttg caacttctgtgtgaggggcacaatggagatttccagaacttccttcgaacccaaactgga aacacaaccacagtcaacatcattatcagcactgtggactatctgctccgtcttcaggaa tccatcagtgacttctactggtactactccggcaaagatgtcatcgatgagacgggaaaa atcaacttctccaaggctttgtttgtagccaagcagatattcaactctctgactgagtat attcagggcccgtgtattgggaaccagcagagtcttgctcacagcagactgtgggatgcc gtcgtgggcttcttgcatgtatttgccaacatgcagatgaagctttctcaggatgccagt caaattgagctgttgaaggagctgatggatttacagaaggacatggtcgtcatgttgctg tctctgctggagggtaatgtggtgcatggtacaattggaaagcagatggtcgacactctg gtggagtcgtccaacaatgtggagatgatcctcaagttcttcgacatgttcctcaaactg aaggatctgacgacctccgaaaacttcagggagtacgaccccgagtgcaaaggcatcatt tcaaagaaggagttccagaagtccatggagagtcagaaacagtacagccagtctgagatc gacttcctgctctcgtgcgcagaggccgatgagaacgatatgtttaattacaaggagttc gtggggcgattccatgagccggccaaagatatcggcttcaatgtggcagtgctgctgacc aacctgtcggagcacatgccccacgactctcgactcgccaccttcttggatctggcagag agtgtgctgagctactttgaaccttacctgggtcgcattgaaatcatgggcagtgcgaag cgcatagagaggatttactttgagatcagcgagtcgagccgcgagcagtgggagaagccg caggtcaaagagtccaagcgtcagttcatctttgacgtggtcaatgagggcggagagagc gagaagatggaaatgtttgtgaatttctgtgaggacaccatctttgagatgcagctggcc tcgcagatctctgagccggacgtggtcgaacaacccgaggaggaagacgatgaggacgga cacagcatcctggaagagctggccgcagaggaggaaggcgccgcggagtcggcctccgcc ttctccaccgcctgttgctcagtcaagaagaagtttgcgcaggtccgccaaaaatgttcc ttaaaaaacgtacgcaagcagttcaggaaagtcatgaaactgagcatcaaggagataatc acaggcgtattctccttcttctggatgctcttcactggcttcttcaaaggaatctacagc ctcatctttggtttcttccacgtcatctggtcctccatgtttggcggtggcctggtggag ggtgccaagaacattaaggtgacggacatcctcggaaacatgcccgacccgacccaattc ggcatccacctcgacgtggtcgaaggagagaaagtggaggccatagagtcatcggggagt ttggatatcaccatggcaccggtaggggagatagcagaggtggacatgatgatggagatt ctgacggggcctaaaagggaaggagggaaacacgtggagctcggcctgggtgacgtgtct gagctgagtgccgaaacatccactgccgatcaaaaaaagaaagctgctgacaagcccttc gaaacccccgagagtgaacccgaaaaagcagacacagagaaccaggagaaggaggacaag ccgaagaaggaggaggcggctaaggaaccggtgactgaggagaagcccaagaccagaacc aaccagcctaaagaggccgcgcccgccttcatgtccactgtctttgcggctctggacgtc ttcacgaacaagatgctgaactacctggctcgcaacttctacaacctgcgtttcctggct ctgttcgtgtgctttgccatcaatttcattctgctcttctacaaggtcactggtgaagtt gacgaagaagtcgaggatgaaagcagctggactgaggacgaagaggcggacgatgagaac acactttttgacatggatgagtttgtgcttcaggagagcagtggttacatgttaccagcg ctgcgctttttggctatattccacaccgtcatctccctcgtgtgcttggtcgggtactat tgtctgaaggttcctctggtggtgttcaagagggagaaggagatcgccaggaagcttgaa tttgacggtctctacattactgagcagccgtctgacgaggacatcaagggccagtgggat cgactcgtcatcaacaccccgtctttccccagcaactactgggacaagttcatcaagcgc aaggtgatcaacaaatacggtgacatgtacggagctgaacgcatcgctgagctcctgggc ctggacaagagcgctctcgactttgaccccacagtggagactgtggagaaggaagcctcc ctgctctcctggctgagctccatcgataccaagtaccacatctggaaaatgggcgtggtt ttgaccgacaactccttcctctatctgatctggtacgccaccatctccatttttggacac ttcaacaacttcttctttgctgctcatttgctggacatcgccatgggcatcaagaccctt cgcaccatcctgtcttctgtcactcacaacgggaagcagcttgtgctgaccgtgggtctg ctcgccgtggtcgtctatctctacaccgtggtggccttcaacttcttcaggaagttctac aacaagagcgaggacgaggacgagccggacatgaagtgcgacgacatgatgacgtgctac ttgttccacatgtacgtcggcgtgagagctggaggaggcatcggagacgagctggaggac ccagctggagacccctacgagctctaccgcatcctgttcgacatcaccttcttcttcttc gtcatcgtcatcctgctggccatcattcaaggtttgatcatcgatgcctttggtgagctg agagaccagcaggagcaggtgaaggaggacatggagaccaaatgcttcatctgtggaatc ggcaacgactactttgaccggactcctcacgggttcgagactcacaccttacaagagcac aacctggcaaactacctgttcttcctcatgtacctgatcaacaaggacgagaccgaacac acgggtcaggagtcgtacgtgtggaagatgtaccaggagagatgctgggacttcttcccg accggagactgcttccgtaagcaatatgaggaccagttgggttag

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