Streptomyces mobaraensis: J7W19_03235
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Entry
J7W19_03235 CDS
T07674
Name
(GenBank) alpha/beta fold hydrolase
KO
K24569
avermectin polyketide synthase AveA4
Organism
smob
Streptomyces mobaraensis
Pathway
smob00522
Biosynthesis of 12-, 14- and 16-membered macrolides
smob01052
Type I polyketide structures
smob01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
smob00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01052 Type I polyketide structures
J7W19_03235
00522 Biosynthesis of 12-, 14- and 16-membered macrolides
J7W19_03235
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins [BR:
smob01008
]
J7W19_03235
Polyketide biosynthesis proteins [BR:
smob01008
]
Polyketide synthase (PKS)
Modular type I PKS
cis-AT PKS
Avermectin PKS
J7W19_03235
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ketoacyl-synt
Acyl_transf_1
Ketoacyl-synt_C
KAsynt_C_assoc
Thioesterase
PP-binding
Thiolase_N
PKS_DE
Docking
SAT
Abhydrolase_6
Abhydrolase_1
Abhydrolase_3
Abhydrolase_5
Motif
Other DBs
NCBI-ProteinID:
QTT72582
UniProt:
M3AVJ7
LinkDB
All DBs
Position
complement(850125..857771)
Genome browser
AA seq
2548 aa
AA seq
DB search
MGTEEKTAASGGGAPQRTEDKLRYYLKRVTADLGETRRRLEEMEAVAGEPIAVVGMACRF
PGGVGSPEELWRLVDEGRDAVEPFPADRGWDLDALYHPDPDHPGTCYAREGGFLRGADRF
DAGFFGIGPREALAMDPQQRLLLETSWEALERAGIDPETLRGSRAGVFVGTGHQEYGALL
QRATENFEGYLLSGSAASVLSGRLSYVLGLEGPAVTVDTACSSSLVTLHLACQSLRRGES
TVALAGGAAVMASPGMFVEFSRQRGMAPDGRCKAFAASADGTGWGEGVGMLVLERLSDAR
RNGHPVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIWQALADARLSARDVDAVEAHGTGT
RLGDPIEAQALLATYGQDRPAEQPLLLGSLKSNIGHTQAAAGVAGVIKTVLALRHGVLPR
TLHVDEPTPHVDWSAGAVELLTERREWPDTGRPRRAGVSSFGVSGTNAHVILEQAPEEEP
ATPAEVVEVLPWPLSAKSAGALRAQAERLATHLDSRPDADPAAVGWTLATGRTAFAQRAV
VVGGPGELGAGVRELAASGAAPGLVTGEAAATHDGAVFVFPGQGSQWAGMAVGLLDTSTV
FRESAEACERALKPYVDWSLTDVLRGTPGAPGLERVDVVQPVLWAVMVSLAALWRSMGVE
PVGVVGHSQGEIAAACVAGGLSLEDGARVAALRSRAIGEILSGSGGMVAVTLGADAVAGL
LDGLGDRASVAAVNGPQSTVVSGEPAALEELLARCEAREIRARRVPVDYASHSAQVERVR
ERVLADLAGIRPRTGTVPFHSTLTGGTVDTAGLDADYWYRNLRETVRFAPVVRDLLAQGE
GAFVECSPHPVLTVGIEEAAQDADMPAVAVGSLRRDEGDWRRFLTSVAEAHTRGLAVDWA
PAFPPATRRLADLPTYAFQRRGYWVETRPGDRDPLEERFWTAVADEDHDGLAALLELADP
DELARLDALLPTLSAWWSRRAERAPRVREEEEPDTAASALRRRLEGLPEAERVRVLVDLV
AAHAVAVLGQEVRVEPGRPFNEIGFVSLTAVELRNRLRAATGLPLPATVVFDHPTPEALS
RRILAELLGEDARDVPPAALTTAPDDDPIAVVGMACRFPGGVAGPEDLWRLVADGRDAIT
PFPENRGWDLEAVYDPDPAHPGTTYTREGGFIEDADRFDAALFGISPREALAMDPQQRLL
LETAWEAFERAGIDPTSLRGSRTGVFTGSSGQDYTALAAGAAEGLEGYVLTGNAASVISG
RLAYAFGLEGPAVTVDTACSSSLVALHLACQSLRSGESTLALAGGVTVLSTPQAFVGFSR
QRGLAPDGRCKAFSAAADGTAWGEGAGLLLVERLSDARRNGHPVLALVRGTATNQDGASN
GLAAPNGPSQQRVITQALANAGLSPADVDAVDAHGTGTPLGDPIEAQALIAAYGKDRPAG
RPLWLGSVKSNIGHTAAAAGLAGVIKMIKAMEHGVLPRTLHADEPTPHVDWSSGAVSLLT
EQRDWPEPGRPRRAAVSSFGISGTNAHVILEQGAGEALPEPARDAVAPAVGETASGEDGL
VLADGGSVPAEDVSAPVGDVPAPAVGEARPAERGPASAAGARVSVEDGSPSAQGGSVRDV
SAPVVSESAPADGGASAHAASAPARSEAADAGAPGSTPALVPCVLSARGEQALRAQAERL
RAHVAERPGLTPLDVGYSLATTRGALEHRAAVLAADRDGLLAGLAALAGGTPAPHVVRDV
AAGGRTAFLFPGQGSQRPGAGRALYAAFPAYAEALDEVCGHLDAHLEHPLRDVLFAEEGT
PAAALLDDTAYTQPALFATGVALARLLEGWDVVPDRLGGHSIGELTAAHVAGVLSLEDAC
ALVAARGRLMAASSPDGIMVAVEAAEDEVAAALADDDRVGIAAVNGPRATVMSGPCEAVE
RVADLLAARGRRTKRLRVTRGFHSPLMDEVLDAFRSVAAGLDYRAPRVTLVSNVTGEILE
AEEVCTPDYWVRHIRRPVRFHDGVRRLAADGVTTFLELGPGGVLSALVRDALADADGDGR
GAAAVPLLRRGQDEETSLITALARARTRGAAGPGWARFHAERGARRVALPTYAFQRRRYW
PDVVAPAMPGTPVTGGPAPAAAEPVTEGPSLRDRLLPLSGGERERLVTELAATHIAAVLG
HPTTEAVEASVGLPELGFDSLAAAELRTALQAATGLTLSTSLVFDHPTLKALAAHLLAAL
EATAEEEADGGTLAALALRAGELGEFAAFQELLRTASRYRPVFGAGERPAVSPEPVRLSR
GPAGTRLLCFPSFAGRSGAHQYARLAAAAHDTAELWALPAPGFTPGEALPDSLEALARHH
AEDVRRCAPDGPFALLGHSAGGWIAHAVAARLEALGTPADAVVLLDSYVPGSPALSAIQE
EIGRRLRAGGGSLGPGDDRWDDTCLTAMGGYDRLFTGWRPEPLAATPVVHLRAAEPLAAF
ADVPDLSDPSDLPGSPGVGWRAAWPAADTTGEVPGDHFGLAGEHAPGTLRTVLDRLAGRD
GEGQDGTGDGTGPDGTGPGAATEPPHRR
NT seq
7647 nt
NT seq
+upstream
nt +downstream
nt
atggggaccgaggagaagaccgccgcgagcggcggaggcgcgccgcagcgcaccgaggac
aaactgcgctactacctcaagcgcgtcaccgccgacctgggcgagacccggcgccggctg
gaggagatggaggccgtcgcgggcgagccgatcgccgtcgtcggcatggcctgccgcttc
ccgggcggcgtcggcagccccgaggagctgtggcggctggtcgacgagggacgggacgcc
gtcgagccgttccccgccgaccgcggctgggacctcgacgcgctctaccacccggacccc
gaccacccgggcacctgctacgcccgcgagggcggcttcctgcgcggcgccgaccgcttc
gacgccgggttcttcggcatcggcccgcgcgaggcgctggccatggacccgcagcagcgg
ctgctgctggagacctcgtgggaggcgctggaacgggccgggatcgacccggagacgctg
cgcggcagccgcgccggagtcttcgtcggcaccggccaccaggagtacggcgccctcctc
cagcgcgccaccgagaacttcgagggctacctgctctccggcagcgcggccagcgtcctc
tccggccggctgtcgtacgtcctcggcctggagggccccgccgtcaccgtcgacaccgcc
tgctcctcgtcgctggtgaccctgcacctggcctgccagtcgctgcggcgcggcgagtcc
acggtggcgctggccggcggcgcggcggtcatggcgtcgccgggcatgttcgtcgagttc
agccggcaacgggggatggcccccgacggccggtgcaaggcgttcgccgcctcggccgac
ggcaccggctggggcgagggcgtcggcatgctcgtcctcgaacggctctccgacgcgcgc
cgcaacgggcatccggtgctcgccgtcgtccgcgggtccgccgtcaaccaggacggcgcc
tccaacgggctcaccgcgcccaacggcccgtcccagcagcgggtcatctggcaggcgctc
gccgacgcccggctctccgcccgcgacgtggacgccgtcgaggcgcacgggacgggcacc
cggctcggcgaccccatcgaggcgcaggcgctcctggccacgtacgggcaggaccgtcct
gccgaacagccgctgctgctcggctcgttgaagtccaacatcggccacacgcaggccgcg
gcgggcgtcgccggcgtcatcaagaccgtgctggcgctgcgacacggcgtcctcccgcgc
accctgcacgtcgacgagccgaccccgcacgtcgactggtcggccggcgccgtcgagctg
ctcaccgagcggcgggagtggccggacaccggccgcccccggcgggccggcgtatcctcc
ttcggcgtcagcggcaccaacgcccacgtcatcctcgaacaggcgccggaggaggagccg
gccacgcccgccgaggtcgtggaggtgctgccctggccgctgtccgccaagagcgcgggc
gccctgcgcgcccaggccgaacgcctcgccacgcacctcgactcccggccggacgccgac
ccggcggccgtcggctggacgctcgccaccgggcggaccgccttcgcccagcgggccgtc
gtcgtcggcggacccggcgaactcggcgcaggcgtacgggaactggcggcctccggtgcc
gcgcccggcctggtcaccggcgaggccgccgccacccacgacggcgcggtcttcgtcttc
cccggccagggctcccagtgggccggcatggccgtcggcctcctcgacaccagcacggtc
ttccgggagagcgccgaggcgtgcgagcgggccctgaaaccgtacgtggactggtcgttg
accgacgtcctgcgcggcacgcccggcgcccccgggctggagcgcgtcgacgtcgtccag
ccggtgctgtgggccgtgatggtgtcgctcgcggcgctgtggcggtcgatgggcgtggag
cccgtcggcgtcgtcgggcactcgcagggcgagatcgccgccgcctgcgtcgcgggcggc
ctgtcgctggaggacggcgcccgggtggccgcgctgcgctcccgggccatcggcgagatc
ctgtccggcagcggcggcatggtggccgtcaccctcggcgcggacgccgtcgccggactg
ctggacggcctcggcgaccgggcgtccgtcgccgccgtcaacgggccgcagtccaccgtc
gtgtccggtgaacccgccgccctggaggagctgctggcccgctgcgaggcgcgggagatc
cgcgcccggcgcgttcccgtcgactacgcctcccactccgcccaggtggagcgcgtccgc
gagcgcgtcctcgccgacctggccggcatccggccgcgcaccgggaccgtccccttccac
tccacgctcaccggcgggacggtcgacaccgccgggctggacgccgactactggtaccgc
aacctccgcgagaccgtccgcttcgcgcccgtcgtccgcgacctgctcgcccagggcgag
ggcgcgttcgtcgagtgcagcccgcaccccgtcctcaccgtcggcatcgaggaggccgcg
caggacgcggacatgcccgccgtcgccgtcggctcgctccgccgcgacgagggcgactgg
cgccgcttcctcacctccgtggccgaggcgcacacccgcggcctcgccgtggactgggcc
ccggccttcccgcccgccacccgccgcctcgccgacctgcccacctacgccttccagcgg
cgcggctactgggtcgagacccgacccggcgaccgggacccgctggaggagcggttctgg
acggccgtcgccgacgaggaccacgacgggctcgcggccctcctcgaactggccgacccc
gacgaactcgcccggctggacgccctgttgccgaccctgtcggcctggtggtcccggcgc
gccgaacgcgctccccgggtacgggaagaggaggagcccgacacggccgcgtccgcgctg
cgccggcggctggagggactgcccgaggccgaacgggtccgggtgctggtcgacttggtg
gccgcgcacgccgtcgccgtgctcgggcaggaggtacgggtcgagcccggaaggccgttc
aacgagatcggcttcgtgtcgctcaccgccgtggagctccgcaaccggctgcgcgcggcg
acgggcctgccgctcccggcgacggtggtcttcgaccacccgaccccggaggcgctgagc
cgccggatcctcgccgaactcctcggcgaggacgcgcgggacgtcccgcccgccgccctg
accacggcgcccgacgacgatccgatcgccgtcgtcggcatggcctgccgcttcccgggc
ggcgtcgccggccccgaggacctctggcgtctggtggccgacgggcgcgacgcgatcacc
ccgttccccgagaaccggggctgggacctggaagccgtctacgatcccgaccccgcccac
cccggcaccacctacacccgcgagggcggcttcatcgaggacgccgaccggttcgacgcc
gcgctgttcggcatcagcccccgcgaggcgctggccatggacccgcagcagcggctgctg
ctggagaccgcctgggaggcgttcgaacgcgccggcatcgacccgacgtcactgcgcggc
agccgcaccggcgtgttcaccggctccagcggccaggactacaccgcgctggccgccggc
gcggcggagggcctggaggggtacgtcctcacgggcaacgccgccagtgtcatctccggc
cgcctcgcctacgcgttcggcctggaaggcccggccgtcacggtggacaccgcctgctcc
tcctccctggtggccctgcacctggcctgccagtcgctgcgttcgggcgagtcgacgctc
gccctcgcgggcggggtgaccgtgctgtccacgccgcaggcgttcgtcgggttctcccgg
cagcgcgggctggcgccggacgggcgctgcaaggcgttctcggccgccgccgacggcacg
gcctggggcgagggcgccggactgctcctcgtcgagcggctgtccgacgcgcgccgcaac
ggccaccccgtcctcgccctggtccggggcaccgccaccaaccaggacggcgccagcaac
ggcctcgccgcccccaacggcccgtcccagcagcgcgtcatcacccaggccctggccaac
gccggactgtccccggcggacgtggacgccgtcgacgcccacggcaccggcaccccgctc
ggcgaccccatcgaggcccaggcgctgatcgccgcctacggcaaggaccgccccgccggc
cgtccgctgtggctgggctcggtgaagtccaacatcggccacacggccgccgcggcgggc
ctggccggcgtcatcaagatgatcaaggccatggaacacggcgtcctgccccggaccctg
cacgccgacgaacccaccccgcacgtcgactggtcgtccggcgcggtgtccctgctgacg
gagcaacgggactggccggagcccggccgcccgcgccgggcggcggtctcgtcgttcggc
atcagcggcaccaacgcgcacgtcatcctggaacagggggcgggggaggcccttcccgag
cccgcgcgggacgcggtcgcgccggcggtgggggagacggcgtccggggaggacggcctt
gtgctcgcggacggcggttcggtgccggccgaggacgtgtcggcccccgtgggggacgta
ccggcaccggcggtgggtgaggcgcggcccgcagagcgcgggccggcgtccgcggcgggc
gcgcgggtatccgtggaggacggttcgccgtcggcccagggcgggtccgtccgggacgtg
tccgcgccggtggtgtccgagtcggcaccggccgacggcggcgcgtccgcacacgcggcc
tccgctcccgcgcggagtgaagcggcggacgccggagcccccgggagcacgcccgcgctc
gtcccctgtgtcctctccgcccggggcgagcaggccctgcgcgcccaggccgagcggctg
cgcgcccacgtcgccgagcggcccggtctgacgccgctggacgtcggctactccctcgcc
accacgcgcggagcgctggagcaccgggccgccgtcctcgcggccgaccgcgacggcctg
ctcgccgggctggccgcgctggccggcggcacaccggcgccgcacgtcgtccgcgacgtc
gccgccggcggccggacggccttcctcttccccgggcagggcagccagcgcccgggcgcc
ggccgcgcgctgtacgcggcgttcccggcctacgcggaggcgctggacgaggtctgcggc
cacctggacgcgcacctcgaacacccgctcagggacgtgctgttcgccgaggaggggacg
cccgccgccgcgctgctcgacgacaccgcgtacacccagcccgccctgttcgcgacgggc
gtcgcgctcgcccgcctgctggagggctgggacgtcgtcccggaccggctcggcgggcac
tcgatcggcgagctgaccgccgcccacgtggcgggcgtgctctccctggaggacgcctgt
gccctggtcgccgcccgcggccggctgatggcggcctcctcacccgacgggatcatggtc
gccgtcgaggccgccgaggacgaggtggccgccgccctggccgatgacgaccgggtgggg
atcgcggccgtcaacggcccccgcgcgacggtgatgtccggcccgtgcgaggccgtcgaa
cgggtggccgatctcctcgccgcccggggccgccgcaccaagcggctgcgcgtgacgcgc
ggtttccactcgccgctgatggacgaggtgctggacgccttccggtccgtcgcggccggg
ctcgactaccgcgcccctcgcgtcaccctggtgtccaacgtgaccggagagatcctggag
gcggaggaggtgtgcaccccggactactgggtgcggcacatccgccgcccggtgcgcttc
cacgacggcgtccggcggctggccgccgacggcgtgacgacgttcctcgaactcggcccg
ggcggtgtcctctcggcgctggtccgggacgcgctggcggacgcggacggggacgggcgc
ggcgccgccgccgtaccgctgctccggcgcgggcaggacgaggagacgagcctgatcacc
gccctcgcccgggcccggacacgcggcgcggcgggccccggctgggcacgcttccacgcc
gaacgcggcgcccggcgcgtcgcgttgcccacctacgccttccaacggcggcgctactgg
cccgacgtcgtcgcccccgccatgccgggaacccccgtcaccggcggcccggctccggcg
gccgccgaacccgtcaccgaaggaccgtcgctgcgcgaccgcctcctgccgctctccggc
ggcgaacgggagcgcctcgtgaccgagttggcggcgacgcacatcgccgccgtgctcggc
caccccacgacggaggccgtggaggcgagcgtcggcctgcccgagctgggcttcgactcg
ctcgccgccgccgagctccgcaccgccctccaggcggccaccggcctcaccctgtccacc
tcgctggtcttcgaccaccccaccctcaaggcgctcgccgcccacctgctggccgccctg
gaggccaccgccgaggaggaggcggacggcggcaccctcgccgcgctcgccctgcgggcc
ggggaactcggcgagttcgccgccttccaggaactgctgcggaccgcctcccgctaccgt
ccggtcttcggcgcgggcgagcgcccggcggtgagcccggagcccgtccggctctcccgg
ggcccggcaggcacccgcctgctctgcttcccgtcgttcgccggccgctccggggcccac
cagtacgcccggctcgccgcggcggcccacgacacggccgagctgtgggccctgcccgcc
cccggcttcaccccgggcgaggccctccccgacagcctggaggcgctcgcccgccaccac
gccgaggacgtccggcgctgcgcccccgacggcccgttcgccctcctcgggcactccgcg
ggcggctggatcgcccacgccgtcgccgcccggctggaagcgctcggcaccccggccgac
gccgtcgtcctgctcgacagctacgtccccggcagcccggcgctgtccgcgatccaggag
gagatcggccggcggctgcgcgccggcggcggctccctcggccccggcgacgaccgctgg
gacgacacctgcctgaccgccatgggcggctacgaccggctgttcaccggctggcggccg
gagccgctggccgccaccccggtcgtccacctgcgggcggccgaaccgctggccgcgttc
gcggacgtcccggacctctcggacccgtcggacctcccgggctccccgggcgtcggctgg
cgggccgcctggcccgcggcggacaccaccggcgaggtgcccggcgaccacttcggcctg
gccggagagcacgccccgggcaccctgcgcaccgtcctggaccggctcgcgggccgggac
ggcgaggggcaggacggtaccggagacggcacgggaccggacggcaccggcccgggcgcc
gccaccgagccaccccaccgccgctga
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