Candidatus Karelsulcia muelleri SMDSEM: SMDSEM_149
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Entry
SMDSEM_149 CDS
T00958
Symbol
thrA
Name
(GenBank) aspartokinase/homoserine dehydrogenase
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
sms
Candidatus Karelsulcia muelleri SMDSEM
Pathway
sms00260
Glycine, serine and threonine metabolism
sms00261
Monobactam biosynthesis
sms00270
Cysteine and methionine metabolism
sms00300
Lysine biosynthesis
sms01100
Metabolic pathways
sms01110
Biosynthesis of secondary metabolites
sms01120
Microbial metabolism in diverse environments
sms01230
Biosynthesis of amino acids
Module
sms_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
sms_M00527
Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
Brite
KEGG Orthology (KO) [BR:
sms00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
SMDSEM_149 (thrA)
00270 Cysteine and methionine metabolism
SMDSEM_149 (thrA)
00300 Lysine biosynthesis
SMDSEM_149 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
SMDSEM_149 (thrA)
Enzymes [BR:
sms01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
SMDSEM_149 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
SMDSEM_149 (thrA)
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SSDB
Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_7
ACT
NAD_binding_3
Motif
Other DBs
NCBI-ProteinID:
ACU52860
UniProt:
C7LK98
LinkDB
All DBs
Position
complement(162836..165295)
Genome browser
AA seq
819 aa
AA seq
DB search
MVKVLHFRSSSLVDSESLKKICTFLKKNPKTKNKNIKYVIIISAFYHITDDLIKCGKLAS
KKKKDYKKILKLIEYKHINIINELFNFKKKSCLISNLKKNINKLENICDGIFQVEKLSIF
SLENLISFGVLNSSYLIAEKIKEFDLKVKFKDSRKLILTDYESGCSKIDLKKSYYNLINF
FKKEKSQYIIFPGIIAFSSEITPLERGGADYIAGIVASSLKADLLEICTNVNGIMTANPK
LVSQAYTIRNISYEEAMEFSHFGAKIISPTTIQPVIEKNIPIKIKSLFEKKKKETYIERR
NFFKKKPVTGISGIKQISLITLEGSGMVGIPGFSKRLFKKLSEEKINVIFITQSSSEYSI
AVGIHEKDVLKAKLVIDNEFYIEISNKKIKPLSIERDLCIIALVGEKMKNMHGTSGKIFS
ALGKNRINIRAIAQGSTEKNISVVINKTDFKKAINILHEEFFEKKNKQINLFIIGLGKVG
RNLLDQIYKQKNYLKKEFKLKLRVIGLANSKKMIFKKDGIDIKKYKYYLDKMSYEMDLKK
FMEIMYEINFRNSLFVDNTANINIAMIYENFLKKGIGVITCNKIACSSTYDYYKKLKELS
INFNAPFLFETNVGASLPVISTLNDLINSGDKIYKIEAVLSGSLNFIFNKFLEKKNFLEV
VKEAQNYGYTEPDPRIDLSGIDVMRKILILARECGSNLELENIYKKNFLPEECLNSTSID
HFYNLLKKYNNYFNEIREKTVKKGKKLRFIAKYENGNAYVGLQSIKVDHPFFNLEGKDNM
VLYNTQRYSEQPLIIKGAGAGAEVTASGVLSDIIKASKS
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atggtaaaagtcctacactttagaagtagttcattagttgatagtgaatcattaaaaaaa
atatgtacatttttaaaaaaaaatccaaagacaaagaataagaatataaaatatgttata
attatatctgctttctatcatattacagatgatttaatcaaatgtggcaaattagcttct
aaaaaaaagaaagattataaaaaaatattaaaattaatagaatataaacatattaatata
attaatgaattatttaatttcaaaaaaaaaagttgtctaattagtaatttaaaaaaaaat
ataaataaattagaaaatatctgtgatggaatttttcaagtagaaaagttatcaatattt
tcattagaaaatctaataagttttggagttttaaattcgtcttatttaatagcagaaaaa
attaaagaatttgatttaaaagtaaaatttaaagatagtagaaaattaattttaacagat
tatgaatctggatgttccaaaattgatttaaaaaaaagttattataacttaataaatttt
tttaaaaaagaaaaatcacaatatattatttttccaggaataatagctttttcatcagaa
ataactccattagaaagagggggagcagattatatagcaggtattgttgcctcgtcatta
aaagcagatttattagaaatatgtactaatgtaaatggaataatgactgccaatcctaaa
ttagtctcacaagcttatactataagaaatatatcttatgaagaagcaatggaattctct
cattttggagcaaaaataatatctcctactactatacaaccagtgatagaaaaaaatatt
cctataaaaattaaaagtctttttgaaaaaaaaaaaaaagaaacttatatagaaagaaga
aatttttttaaaaaaaaacctgtaacaggaatttctggaattaaacaaatatcattaata
acattagaaggaagtggaatggtaggaattcctggtttttctaaaagacttttcaaaaaa
ctttcagaagaaaaaataaatgtaatatttattacccaaagttcctcagaatattctatt
gctgtaggaattcatgaaaaagatgttttaaaagctaaattagttatagataatgaattt
tacatagaaatatctaataagaagataaaacctctttcgatagaaagagatttatgtatt
atagcacttgttggagaaaaaatgaaaaatatgcatggaacaagtggaaaaatttttagt
gctttaggaaaaaataggattaatatcagagcaatagctcaaggttccactgaaaaaaat
atttcagttgttataaacaaaacagattttaaaaaagcaataaatattttacatgaagaa
ttttttgaaaaaaaaaataaacaaataaatttgtttataataggattaggaaaagttgga
aggaatcttttagatcagatctataagcaaaaaaattatttaaaaaaagaatttaaattg
aaattaagagtaattgggttagcaaatagtaaaaaaatgatctttaaaaaagatggaatc
gatataaaaaaatataaatattatcttgataagatgtcatatgaaatggatttaaaaaaa
tttatggaaataatgtatgaaattaattttagaaatagtctttttgttgataatacagcc
aatataaatattgctatgatctatgaaaattttttaaaaaaaggaataggtgttattaca
tgtaataaaatagcatgttcatcaacttatgattattataaaaaacttaaagaattatca
ataaattttaatgctccatttttgtttgaaactaatgtaggagctagtttacctgtaatt
agtacactgaatgatttaataaatagtggtgataaaatatataaaatagaagcagtactt
tctgggagtttaaattttatttttaataaatttcttgaaaaaaaaaattttttggaagtg
gtaaaagaagcacaaaattatggatatacagaaccagatccacggatagatcttagtgga
atagatgtaatgaggaaaatattaattttagcacgtgaatgtggatctaatctagaatta
gaaaatatatataaaaaaaatttcttacctgaagaatgtttaaattctacatcaatagat
catttttataatctattaaaaaaatataataattattttaatgaaatacgtgaaaaaact
gtgaaaaaaggaaaaaaattacgttttatagctaaatatgaaaatggaaatgcatatgta
gggttacaatcaataaaagtggatcatccattttttaacctggaaggaaaagataatatg
gtattatataatacccaaagatatagtgaacaacctttaattataaaaggtgcaggtgca
ggtgcagaagttactgcatctggagtattatcagatataattaaagctagtaaatcttaa
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