Spirosoma aureum: G8759_06350
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Entry
G8759_06350 CDS
T06520
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
spib
Spirosoma aureum
Pathway
spib00260
Glycine, serine and threonine metabolism
spib00261
Monobactam biosynthesis
spib00270
Cysteine and methionine metabolism
spib00300
Lysine biosynthesis
spib01100
Metabolic pathways
spib01110
Biosynthesis of secondary metabolites
spib01120
Microbial metabolism in diverse environments
spib01230
Biosynthesis of amino acids
Module
spib_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
spib_M00527
Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
Brite
KEGG Orthology (KO) [BR:
spib00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
G8759_06350 (thrA)
00270 Cysteine and methionine metabolism
G8759_06350 (thrA)
00300 Lysine biosynthesis
G8759_06350 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
G8759_06350 (thrA)
Enzymes [BR:
spib01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
G8759_06350 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
G8759_06350 (thrA)
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GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_7
ACT
NAD_binding_3
Motif
Other DBs
NCBI-ProteinID:
QIP12273
UniProt:
A0A6G9AJB6
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All DBs
Position
1555438..1557909
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AA seq
823 aa
AA seq
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MQVLKFGGTSVGTVESIKQVIQIIDNHRQNGDQITVVFSAMGGITNQLIEIGRMATTGET
DYMELVRRIEDRHFNVIKALIPVKEQSKVFAHIRGIINELEDLLRGVSLIRELTLRTHDL
ITSFGERLSTTVITECVKSRGIPAQFCDARTIIKTNAQFGQAEVNYNLTNQLIQEHFAKT
NDRAGAPVQMVTGFIGSTEKNETTTLGRGGSDYTASILGAALNADIIDIWTDVDGMMTAD
PRKVPNAFNIPTITYAEAMELSHFGAKVIYPPSLQPAFARNIPIRVLNTFNPTHSGTVVS
RTAERRQYTITGISSIDDIALVNVQGSGMIGVAGVSAKLFGVLAAHKISVILISQASSEH
SICFAIDPRGAENVKTILDDEFATEISHGHIDNIVIERDLSVIATVGEGMKKSSGIAGKL
FSVLGKNGVNIVAVAQGSSEINISVVINKNNLSKALNSLHNIFFQSEARVLNLYLVGTGL
IGKTLLKQIFNQFEFLRTEKLLKVCVVGMTNTKKMLLDPKGIALDEWRERLLTEGVTTSL
PAFVEKIQDYNLPNSVFIDCTSDKDIVQFYESLLDANISVVTPNKVANSGSYAEYRRLQR
TALNRGVKFLYETNVGAGLPIINTVQGLMTAGDRFLKIEAILSGTLSFIFNTFRPGISFA
DVVREAKEKGYTEPDPRDDLSGLDVARKILILAREAGFPLEPEDVTITNLLPQSCLDAPT
ISAFFEELERNNAYFENLLVEAESKSEKLRFVASFENNKATIGLRPVGVDHPFYQLTGAD
NIVSFTTERYKERPLVIKGPGAGAEVTASGVFADVVSIGSYLA
NT seq
2472 nt
NT seq
+upstream
nt +downstream
nt
atgcaggttctgaaatttggcggtacgtcggttggcactgtcgaaagtatcaaacaggtt
atccagattattgacaatcaccgacagaatggcgatcagataacagttgtgttttcggca
atggggggtataacaaaccagctcattgaaattggccggatggctaccaccggtgaaacc
gattatatggaattagttcggcggattgaagaccggcacttcaatgtcattaaagcgctg
attcctgtaaaagaacagagtaaagtttttgcccatattcggggcattattaatgaactg
gaagatttactccggggagtgtcgcttatccgcgaactgacgcttcgtactcatgacctc
atcaccagttttggcgaacgcttatccacaacggtcattaccgaatgtgtaaaaagccgg
ggtattccagcgcagttttgcgatgcccgtacaattattaaaaccaatgcacaatttggg
caggcggaagtaaactataaccttacgaatcaactgattcaggagcatttcgccaaaacg
aatgaccgagccggcgctccggtgcaaatggtaacggggtttattggctcgaccgaaaag
aacgaaacaacaaccctcggccggggtggctccgactacaccgccagcatccttggagca
gccctgaacgccgacatcatcgacatctggaccgatgtcgacgggatgatgacggccgat
ccgaggaaggtgcccaatgcattcaatattccgacaattacgtatgccgaagcgatggag
ttgtcgcattttggggcgaaggtcatttatccgcccagcctgcaacccgcttttgcccgt
aacatcccaattcgggtcctgaacacctttaatccaacgcacagcggcacggtagttagc
cgtactgccgaacggcggcaatataccattaccggcatttcgagtatcgacgacatcgcc
ctggtgaacgtgcagggatcgggcatgattggtgttgcgggtgtatcggcgaagttgttt
ggggtgctggcagcgcataaaatcagcgtaattctgatctcacaggcttcatcggaacac
tcaatctgtttcgccatcgatccacgcggtgccgaaaatgtgaaaacgatcctcgacgac
gagtttgctaccgaaatttcgcatggccatatcgacaatatcgttattgagcgcgaccta
tcggtaattgctaccgtgggtgaaggcatgaagaaaagctctgggattgccgggaaactg
ttttcggtactgggcaaaaacggggtcaacattgtggccgttgcgcagggttcgtcggag
atcaatatttcggtcgttattaacaaaaataacctctcgaaagcgcttaactccctgcat
aacatcttctttcagtctgaagcacgggtgctgaatttgtatctggtcggtacgggcctg
atcggtaaaaccctgctgaaacagattttcaaccagttcgaatttctgcgtaccgaaaaa
ctcctgaaggtgtgtgttgtgggcatgaccaataccaaaaaaatgctcctcgatcccaaa
ggcattgctctcgacgaatggcgcgaacggctattgaccgaaggtgtaaccacctcgcta
cccgcttttgtggagaaaattcaagattataacctgcctaactcggtgtttatcgactgc
acgtcggataaagatatcgtacagttttatgagtcgttgttagatgccaacatttcggtt
gtaacgcccaacaaagtggccaattccggctcgtatgccgaataccgacgattgcagcga
acggccctcaaccggggtgtcaagtttctctatgagactaatgtcggggccggattgcca
atcatcaataccgtgcagggcctgatgacagcgggcgaccgtttcctgaaaatcgaagcc
attctgtccggtacgttatcattcattttcaatacgttccggcccggtatttcctttgct
gatgtagtccgggaagccaaagaaaaaggttataccgagcccgatccccgcgatgacctg
agcggactggatgtagcccgaaaaattctcattctggcccgtgaggctggttttccgctc
gaacctgaggatgtaacaatcacgaatctgcttccacagtcgtgtctcgatgcgcctact
atttccgcctttttcgaggagttggaacgcaacaacgcttactttgagaacttgcttgta
gaagctgaatcaaaaagcgaaaaactccggtttgttgccagttttgagaataacaaagca
accattgggctgcggccggtaggagtcgatcacccgttctatcagttaaccggggccgat
aatattgtgtcgttcacaacggaacgctacaaagagcgcccgctggtaataaaaggacct
ggtgctggtgctgaagtaacggcttcgggggtgttcgccgatgtggtcagtatcgggagt
tatttggcgtaa
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