Sardina pilchardus (sardine): 134098549 Help Entry 134098549         CDS       T10667                                  Symbol ryr3 Name (RefSeq) ryanodine receptor 3   KO K04963   ryanodine receptor 3 Organism spil  Sardina pilchardus (sardine) Pathway spil04020   Calcium signaling pathway spil04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:spil00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     134098549 (ryr3)    04020 Calcium signaling pathway     134098549 (ryr3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:spil04040]     134098549 (ryr3) Ion channels [BR:spil04040]  Voltage-gated cation channels   Ryanodine receptor    134098549 (ryr3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_1 EF-hand_7 EF-hand_6 EF-hand_8 Motif Other DBs NCBI-GeneID:  134098549 NCBI-ProteinID:  XP_062407606 LinkDB All DBs Position 12:15862035..15960344 Genome browser AA seq 4844 aa AA seqDB search MAEGGEGEDEIQFLRTEDEVVVQCVAAIQKENRKFCLAAEGLGNRICFLEPTSEAKYVPP DLCICSFVLEQSLSVRALQEMLAKCGPNGEGAVQGGGHRTLLYGHAILLKHSFSGMYLTC LKTSKSQTDKLSFDVGLQEGSVGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERYL HLSMANGNIAVDASFMQTLWNVQPTCSGSNIAVGFVQGGHVMRLFHGHDESLTIPGADKK EDQQRIVNYEAGKGGSRARSLWRLEPLRISWSGGNLRWGQPFRLRHLSTGHYLGQTEDRG LVLLDRENSNTAATSFCFRASKEKVESGPKRDIEGMGVAEIKYGDSVCFVMHVATGLWLS YQAPDAKSSRLGPLKRRAFLYPEGHMDDGLILQLCQHEESRAARIIRNTTVLFSQFIKAL DSLQEEKSNEVSLPVGEVRESLNDLIVYFQQPDSELEHEEKQRQLRSLIKRQDLFKEEGM LTLLVKCINCLNVYNSAAHFEEFAGVEAGEAWKSILNLLYELLAALIRGNRANCTQFSRN LDWLVSKLERLESSSGILEVLHCILVESPEALNIIQKAHIKSIISLLYKHGRNHKILDVL CSLCVCNGVAVRANQNFICDHLLPRRDLLLQTRLVNDVQSMRPNIFLGINEGSAQYKKWY FELMIDQVDHFVTSEPTHLRVGWATTKGYAPYPGGGEGWGGNGVGDDLYSYSFDGLHLWS GRIPRAVASINQHLLSGDDVVSCCLDLGAPSMSFRINGQPVQGMFEDFNIDGFFYPVVSF SAGVKVRFLLGGRHGDFKFLPPAGYTPCYEALLPKEKMRIEPVKEYKRDHEGVRDILGTT KLLSQASFIPIPVDTSQIVLPPHLEHVRDKLAENIHELWGMNKIELGWTYGKVRDDNKRQ HPCLIDFSKLPETEMNYNLQMSSETLKTLLALGCMVSHVNLNAEEDLKKIKLPKNYVMSN GYKPTPLDLSDVKLNPGQEVLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKSRRNPRLVP YALLDERTKRSNRDSLREAIRTLVGYGYNIDPPDQEPAHALEKKSIETIRFFRVEQTYAV TTGKWYFEFEALTGGDMQVGWARPASRPDIELGMDDLSYVFDGFRGRRVHKGGHFFGRTW SKGDVVGCMINMEDKSMLFTLNGEILITSSGSELCFADFETEDGFIPVCSLGLSQIGRMN LGKDASTFKYYTMYGLQEGFEPFAVNMNREVTMWFSKRLPTFVNVPADHPHIEVTRIDGT VDTPPCLKVSHKTYGTQASNNDMMYCRLSMPVEFYPGPRKNIEGVEVTEVPKKDSGKIDH GSITKYYYSVRVFAGQDPTSVWVGWVTPDYHYYSKNFSLSKIRTVTVTLGDERGRVHESL RRSNCYMVCGGDIGLGSSSSRSNVDIEIGCFIDLASGIVSFTANGKELPTTYQVEPNTKL FPAAFILPTSPNLLQFEFAKIQDAMPLSSAIFKSLHRNPVPQCPPRLDVQTIVSVLWSRM PNTFLSVETARVSERHGWVVQCLDPLQMLAVHIPEENRCLDIMELSENEALRQFHYHTLK LYCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLTGQLRAGFYDVLISIHLDRAKEARL MMKDEYIIPVTSETRGIRLFRDASKSHTLPGVGLSTTLTPGLTFSPPCFIGTKRDQHMHS PQMPLAKLKAKAISMLTEAVHGGGVHIRDPVGGSVEYQFVPILKLISTLLIMGALTSEEV RLVLLLIEPNVFQEPEEASGGGAGGGGALAVEAAPGKEVVTSAEGKAVEAGEEEAKEAKP PTRGLLEKHLPESVKLQMCVLLHYFCDCELKQRIEAIVAFADAYVSKLQYNQKFRYNELM QALNMSAAVTAKKTKEFRSPPQEQINMLLNFALGEDCPCPEEIQDELHIFHDDLRIHCGI PIEDEEEEPDTSIKGRLMSLVYKIKGRPHKTEAEPTEEEQAAPTNLKELISQTMVTWAQE CLVQDPQLVRTMFSLLRRQYDGIGELLRSMKKSYTISAASVQDAIHLLASLGQIRSLLSV RMGIEEERLMIDGLSDIMNNKVFYQHPNLMRVLGMHETVMQVMVNVLGGDDKSQIAFPAM VASCCRFLCYFCRISRQNQKAMFDHLSYLLENSCVGLASPAMRGSTPLDVAASSVMDNNG LALALEEPDLEKVVTYLAGCGLQSCAMLVNRGYPDIGWNPMEGERYLSFLRFAVFVNGES VEENANVVVKLLIRRPECFGPALRGEGGQGLLAAMQEAITISEDPALDLPTVPEGGLPEA VEGEEEEEVTHIGNAIMSFYSALIDLLGRCAPEMHLISKGKGEALRIRAILQSLVPTMDL VGIISIPLKMPVVNKDGSVTEPDMSASFCPEHKAPMVLFLDRVYGIRDQAFLLQLLEVGF LPDLRASASLDTEVLSTTETALAMNRYIGSAVLPLLTRCAHLFSSTEHYAALIDSTLHTI YRLSKGRSLTKAQRDAIEECLLAICSHLRPSMLQQLLRRLVFDVPLLTEYCKMPIRLLTN HYEQNWKYYCLPTGLGSYGIASEEELLLTKKLFWGLFDAVSQKKYEPDLFKLAMLCLSAI SGALPPDFVDASPASTLEKQTSVDAQGNFDPKPISTANISLPEKLEYIANKYGEHSHEKW SSEKLAQGWNRGEKVDNEAKTHPLLQPYKSLSEKERETYRYPVKESLKSMLAMGWTVERT KEGEAIFQQRESEKQRKISESGAFTPTPLDLDNVVLSRELQGMVEIVAENYHNIWAKKKK AELASKGGGSHPLLVPYDTLTAKEKYRDREKAQELFKFLQVNGYAVIRQHQSMEQESASM EKRLASKFLKRLLNYVDSAQEFIAHLEAMATSGKTDKSPHEQEIKFFAKVLLPLIDQYFK NHSLYFLSTPSKNLSSSGYATNKEKERIASLFCKLAALVRHRISLFGADSPTMVSCLHIL AHSLDFRTVMKSGSELVKAGVRGFFDNAAEDLEKTMENLKLGKQTQRTQMKGVSQIINYT ITALLPVLTALFQHVSHHHFGGDLLLDDVQLSSYRILTSLYSLGTGKNSYVEKQLPTLGE CLSTLVSAMPVAFLETHLDAHNPLSVFNTKTPRERAILSMPDSVTEMCPEMPELDGLLKD ISDLSESGARYSDMPQVIEVVLPMLCTYLSTWWDKGPDNNSGSSGCCTSVSSEHLSTMLG NILRILNNNLGIDEAPWMKRLAVFTQPVICKAGSDLLKSHFLPTLEKMRKKTVKVVSEEE ALKADTKGDTQEMELQILDEFAVLCRDLYAFYPMLIRYVDNFRSKWLKEPDDDSTTLFNM VAEIFILWCKSHNFKREEQNFVVQNEINNLAFLTVDSKTKMAKSGGEDQERKGRRRKREL YSVQTSLIVAALKKLLPIGLNMCTPGEQELITLAKIRYGLKDTDDEVKDHLRQNLHLQEK SDDPAVQWQVNLYKDVVVKSEGPPDPEHIVVRVQGLSAALFHLDAVELPLRNKKNLTQKL LSKQRKRAVVACFRMAPLYNLPRHRCINHFFLAYQRFWIEAEEYFFEEKLVQDLAKTPIK VADEEEEEEAEVKPDPLHQLILHFSHNALTERSQLDEDPLYIAYADMMAKSCAEDEEEEE DEEGAKSFEEKEMEKQKILYQQARLHARGAAEMVLQMISASKGRLGPMVTGTLKLGISIL SGGNVIVQQKMLDYLKLKRDAGFFKSLTGLMQACSVLDLNAFERQNKAESLGMMSEEGSI NSSEKASKVLQNDDFTKDLFRFLQLLCEGHNADFQNFLRTQTGNTTTVNIIISTVDYLLR LQESISDFYWYYSGKDVMDEAGQYNFSKALAVAKQVFNSLTEYIQGPCIGNQQSLAHSRL WDAVVGFLHVFANMQMKLSQDSSQIELLKELMDLQKDMVVMMLSLLEGNIVNGTIGKQMV DTLVESSSNVEMILKFFDMFLKLKDLTTSDNFKEYDPDSKGIISKKEFQKAMENQKQYMQ SEIDFLLCCAEADENDMFNYEEFVDRFHEPAKDIGFNVVVLLTNLSEHMPHDNRLATFLD LADSVVNYFEPYLGRIEIMGSAKRIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEG GESEKMEMFVNFCEDTIFEMQLASQISEPEVVERHEEEEEEEDEPEEEEEGVESQSAFSA ACGSVKRKISNFRQMLTLRSMGKQFKAMRKLTIREMIAGFFGFFWMLFTGFFKGIYNVIF GFFHIIWTSIFGGGLVEGAKNIKVTDILGNMPDPTQFGIHGDVLEAEKADIGEMVAAADM AQMASGEPVEVDVMMELMGGAAKRDAKHELGLGDVCEIKPAESAAPEKKKSKKAEVKESE PEKADTENQEKEEKAKEEVPAEPAAKDKPARKPRRGADQEESPAFMASFVAGLEVYKTKM LNYLARNFYNLRMLALFVAFAINFILLFYKVTADEVDEDEDSWENGDDEEDDEGLEYFVL QESTGYMAPTLTFLALSHTLISLLCVLGYYYLKVPLVVFKREKEIARSLEFEGIYITEQP SDDDIKGQWDRLVINTPSFPSNYWDKFIKRKVINKYGDLYGAERIAELLGLDKSALDFDP TIETVAPEASLVSWLSSIDTKYHTWKMGVVLTDNSFLYLVWYTTMSSLGHYNNFFFAAHL LDIAMCFKPLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPD MKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDPSELYRILFDITFFFFVIVILLAIIQ GLIIDAFGELRGQQDQVKEDMETKCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLM YLINKDETEHTGQESFVWKMYQERCWDFFPAGDCFRKQYEDQLG NT seq 14535 nt NT seq  +upstreamnt  +downstreamnt atggctgagggtggagaaggggaagatgaaattcagttcttaagaactgaagatgaagtg gttgtacagtgcgtcgccgcaatccagaaagaaaaccgcaagttttgcctggcagcggag ggactcggaaaccgaatctgtttcttggaaccgacctctgaggctaagtatgtccctcca gacctgtgcatctgcagctttgtgctggagcagtcgctgtcagtacgggccctgcaggag atgctggccaagtgtggccccaatggcgaaggggcagtgcaaggaggtggacatcggacc cttctgtacggccacgccatcctactgaagcactccttcagcggaatgtatcttacgtgt ctgaagacatcaaagtcccagacagacaagctatcttttgacgtgggtctgcaggagggt tcagtgggagaggcctgctggtggacgatccatcccgcgtctaagcagaggtcagaaggc gagaaggtccgcatcggtgatgatctgattctggtcagcgtgtcttcagagagatacctg cacctgtccatggctaatggcaacattgcggtggatgcctccttcatgcagaccctctgg aacgttcagccaacctgctctggcagcaacatagccgtaggttttgttcagggtggtcat gtgatgcgcctgtttcacggacacgacgagagcctcaccataccaggggcagacaagaaa gaggaccagcagaggatagtgaattatgaagcaggtaaagggggttccagggccaggtct ctgtggagattggagcctcttcggatcagttggagtgggggtaatttgagatgggggcag cctttccgcctccgccatctttccaccggccactacctgggccagacggaggaccgcggc ctggtcctgctggaccgcgagaactccaacaccgcggccacgtcattctgcttcagggcc tccaaggaaaaagtggaatctggcccgaagcgagatatcgaaggcatgggagtggcggag attaagtacggagactcggtctgcttcgtcatgcatgtggccaccggactttggctgtcc tatcaagcgccggacgccaaatcctctcgcctcggccctctcaagagaagggcctttctg tacccagagggccacatggacgatgggctgatcctgcagctctgccagcacgaggagtcc agggccgcccgcatcatccgcaacaccaccgtcctgttcagtcagttcatcaaggctctg gacagtctgcaggaggagaagagcaatgaggtgagcctgcccgtgggtgaagtgcgggag tctctgaacgacctcatcgtctacttccagcagcccgactcggagctggagcacgaggag aagcagcggcagctgcgctccctcatcaagcgccaggacctcttcaaggaggagggaatg ctgacacttctggtcaaatgcatcaactgtctgaatgtctacaacagcgctgcccacttt gaggagtttgccggagtagaggctggagaagcctggaagagcattctaaacttgctttac gagctcctggccgccctcatccgtggcaacagggccaactgtacacagttctcccgcaac ctggactggctggtcagcaaactggagaggctcgagtcctcatcaggaattctagaggtt ctccactgcattctggtggagagtcccgaggccctgaacatcatccagaaagcacacatt aaatccatcatctctctgctgtacaagcatggacgcaaccacaagattctggatgtcctc tgctcgctctgcgtttgcaatggtgtggccgtccgagccaatcaaaacttcatctgtgac cacctgctccctcggagagatctgctcctgcagacacgactggttaatgatgttcaaagc atgcgacccaacatcttcctgggcattaacgagggatctgcccagtataaaaagtggtac tttgagctgatgatcgaccaggtggaccactttgtgaccagcgagcccacccaccttcgt gtcggctgggccaccactaaaggctacgccccgtaccccgggggtggagaaggatggggg ggcaacggcgtgggtgacgacctttactcctacagcttcgacgggcttcacctctggtca ggtcgtattcccagggcggtggcgtccatcaaccagcacctgctgagtggcgatgacgtg gtgagctgctgcctggacctgggcgctccgagcatgtccttccgcatcaacggccagccg gtgcagggcatgttcgaggacttcaacatagacggcttcttctacccagtcgtcagcttc tcggcaggggtcaaggtacgcttcctgttgggtggccgccacggtgacttcaagttcctg ccgcctgccggctacacgccgtgctacgaagccctgctccccaaagagaagatgcgcatt gaaccggtgaaggagtacaagcgtgaccacgagggcgtccgagacatactgggcaccaca aagctcctgtcccaagcctccttcatacccatccctgtggacaccagccagattgttttg ccccctcacctagagcatgtgagggacaagctcgctgagaacatccatgaactctggggc atgaataagatcgaactcggctggacttatggcaaggtgcgagatgacaacaagagacag cacccctgtctcattgacttctccaaattgcccgagaccgaaatgaattataacctgcag atgtcatccgagacattaaagaccttactggctttggggtgcatggtttcccatgtcaac ctcaatgcagaggaggatctgaagaaaatcaaacttcctaagaattacgtgatgtctaac ggttataaacccacgccactggacctttctgacgtgaagctgaatcctggtcaggaagtt ctggtagataaattggccgagaacgctcacaacgtttgggccaaagatagaatcaaacaa gggtggacctatggcatacagcaggatctgaagagcagacgcaatcctcgcctggtgcca tatgctttactagatgagcgcactaaaagatccaaccgcgacagtctccgcgaggctatc cgaacactggtcggatacgggtacaacattgaccctccagaccaagagcctgcccacgca ttagagaagaagagcatcgaaactatccgcttcttccgcgtggagcagacttatgcggtc accactgggaagtggtactttgagtttgaagctttgacaggcggagacatgcaggtgggc tgggctaggcccgcctccaggcctgacatagagctgggaatggacgacctctcatatgta tttgatggtttccggggccgacgcgtacataaaggaggtcatttctttggccgcacctgg agcaagggtgacgtggttgggtgtatgatcaatatggaggacaagtccatgctctttact ctgaatggagaaattctcatcaccagtagtggctctgagctgtgcttcgctgactttgag actgaggacggcttcatcccagtgtgtagcctgggactctcccagatcgggcgcatgaac ttgggcaaggacgccagcacctttaagtactacaccatgtacggcctccaggagggattc gaacccttcgccgtcaacatgaaccgcgaggtcaccatgtggtttagcaaacgcctgccc acattcgtcaacgtgccagcggatcacccacacattgaggtgaccaggatcgatggtact gtggacacacccccgtgcctaaaggtgtcccataagacctatggcacacaggcaagcaac aacgacatgatgtactgtcgcctgagcatgcccgtcgagttctaccccgggccaagaaag aacattgagggtgtagaggtaacggaagtgcccaagaaagacagtggcaagattgatcat gggagcatcacaaagtactattactccgtaagagtgtttgctggtcaggatcccacttct gtgtgggtgggctgggttactcccgactaccactactacagcaagaatttcagccttagc aagatccgcaccgtcaccgtaaccctaggagacgaacgaggccgtgtccacgagagcctg aggaggagcaactgctatatggtgtgtggaggggacatagggctcggctcgtcctcctcc cgctccaacgttgacattgagatcggctgcttcatagacctggcctccggtatcgtctcg ttcactgccaatggcaaggagttgcccaccacttaccaggtggagcccaacaccaagctg tttcctgcggcattcattctgccaacaagccctaatttgctccagtttgagtttgcaaag atccaggatgccatgcccctgtcgtcggccatcttcaagagcctgcacaggaacccggtg ccccagtgcccgccgcggctggacgtgcagaccatcgtgtccgtgctgtggagccgcatg cccaacaccttcctgtcggtggagacggcgcgggtcagcgagcgccacggctgggtggtg cagtgcctggacccgctgcagatgctggccgtgcacatccccgaggagaacaggtgtctt gacatcatggagctgtcggagaacgaggctctacgccagttccactaccacacgctgaag ctctactgcgccctctgcgctctgggcaacacgcgcgtggcccacgccctctgcagccac ctggaccaatcgcagctcctctacaccatcgacaaccaatacctgacgggccagctgcgc gccggcttctacgacgtgctcatcagcatccacctggaccgggccaaggaggcgcgcctg atgatgaaggacgagtacatcatccccgtcacctcggagacgcgcggcatccggctcttc cgcgacgcgtccaagagccacacgctgcccggcgtgggcctgagcaccacgctgacgccg gggctgaccttctcgccgccgtgcttcatcggcaccaagcgcgaccagcacatgcacagc ccgcagatgccgctggccaagctcaaggccaaggccatctccatgctgacggaggccgtg cacggcggcggcgtgcacatccgcgacccggtgggcggcagcgtggagtaccagttcgtg cccatcctcaagctcatcagcacgctgctcatcatgggcgcgctcaccagcgaggaggtg cgcctcgtgctgctcctcatcgagcccaacgtcttccaggagcccgaggaggcgtccggc ggaggcgctggtggtggaggcgcgctggcggtggaggccgcgccggggaaggaggtggtg accagcgcggaggggaaggctgtggaggccggcgaggaggaggccaaagaggccaagccg cccaccaggggcctcctggagaagcatctgccggagtcggtcaaactgcagatgtgtgtg ctgctgcactacttctgtgactgtgagctgaagcagcgcattgaggctatcgtggccttc gccgacgcctacgtgtccaagctgcagtacaaccagaagttcaggtacaacgagctgatg caggctctcaacatgtccgctgccgtcaccgccaagaagaccaaggagttccgttccccc ccgcaggaacagattaatatgctgctcaacttcgccctgggggaggattgcccctgccct gaggaaattcaagatgagctgcacattttccacgatgatttgagaatacactgtggaatc ccaattgaagatgaggaggaggagccggacacctccatcaagggccgcctgatgtccctc gtctacaaaatcaaaggccggccgcacaaaaccgaggcggaaccaacagaggaggaacaa gctgctcccaccaacctgaaggagctgatctcccagaccatggtgacgtgggcgcaggag tgcctggtgcaggacccgcagctggtgcgcaccatgttcagcctgctgcggcggcagtac gacggcatcggcgagctgctgcgctccatgaagaagagctacaccatcagcgccgcctcg gtgcaggacgccatccacctgctggcttcgctcggccagatccgctcgctgctcagcgtg cgcatgggcatcgaggaggagaggctcatgatcgacgggctcagtgacatcatgaacaac aaagtcttctaccaacatcccaacctgatgagagtgctggggatgcatgagacagtcatg caagtcatggtcaacgtcctgggaggagacgacaagtctcagatcgccttccccgccatg gtggccagctgctgccgcttcctgtgctacttctgtcgcatcagccggcagaaccagaag gccatgttcgaccacctgagctacctgctggagaacagctgcgtgggcctggcctccccc gccatgcgaggttccacgcccctggacgtggctgcctcctctgtgatggataataacggc ctggccctggcgctggaggagcctgacctggagaaggtggtcacatacctggctggctgt gggcttcagagctgtgccatgctggtgaacaggggttaccctgacattggatggaacccc atggaaggcgagcgatacctctccttcttgcgcttcgccgtcttcgtcaatggcgagagc gtggaggagaacgccaatgtggtggtgaagctccttattcgacggcctgagtgtttcggc ccagccttgagaggcgagggtggtcaaggcctgctggccgccatgcaggaggccatcacc atctccgaggacccggctctggacctccccactgtgcctgagggaggactaccagaggcc gttgagggtgaggaggaggaggaggtgacacacattggcaacgccatcatgtccttctac tctgccctcatcgacctgctgggacgctgtgcccctgagatgcatctcatcagcaagggc aaaggggaagcgctgcgtatccgcgccatccttcagtctctggtgccaaccatggacctc gttggcatcattagcatcccactcaagatgcccgtcgtcaataaagacggttcggtgacg gagccggacatgtcggccagcttctgccccgagcacaaggcgccgatggtgctgttcctg gaccgtgtgtacgggatcagagaccaggccttcctgctccagctgctggaggtgggcttc ctgccggacctgcgggcctcggcctctctggacacggaggtgctgagcaccacggagacg gcgctggcgatgaacaggtacatcggctcggcggtgctgcccctgctgacccgctgcgcc cacctgttctccagcacggagcactacgccgcgctcatcgactccacgctgcacaccatc taccgcctgtccaagggccgctcgctcaccaaggcccagagggacgccatcgaggagtgc ctcctggccatctgctcacacctgcgtccgtctatgctgcagcagctgctgaggcgtcta gtgtttgatgtgcccctgctcaccgagtactgcaagatgcccatcaggctcctgaccaac cactatgagcagaactggaagtactactgcctgcccaccggcctgggcagctacggcatc gcctccgaggaggagctgctactcaccaagaagctcttctggggactttttgacgccgtc tcccagaaaaaatatgagccagacctcttcaagctggccatgctgtgcctgtctgccatc tccggggcgctgccgcccgatttcgtcgacgccagccccgcctccaccttagagaagcag acctccgtggacgcccagggcaacttcgaccccaaacccatcagcactgccaacatttcc ctccctgaaaagctggagtacatcgccaacaagtatggcgagcactcccacgagaaatgg tcttcggagaagttggcacaaggctggaatcgtggagagaaagtggacaacgaggccaaa actcatccattacttcagccgtataaatcactgagcgaaaaggaaagggagacttatcgc tacccagtgaaagagtccctgaaaagcatgttagctatgggctggactgttgagcggacc aaagaaggcgaggccatattccagcaacgagagagcgagaaacagcgcaagatctccgag agtggagccttcactcccacaccactcgatctggacaacgtggttttgtccagagagttg cagggcatggtggagatcgtggccgaaaactaccacaacatctgggccaagaagaagaag gctgagctcgcgagcaaaggagggggctctcacccgctgctggtgccctatgacacgctg acggccaaggagaagtaccgcgaccgcgagaaggcccaggagctcttcaaattcctgcag gtcaacggctacgccgtaatcagacaacaccagagtatggagcaggaatccgctagcatg gagaagaggttggcctccaagttcctcaagaggctgctgaactacgtagactctgcccag gagttcatcgcccacctggaggccatggctaccagtggcaaaaccgacaaatcccctcac gagcaagagattaagttctttgccaaggttctgctgcccctaattgaccagtacttcaag aaccactcactctactttctgtccactcccagcaagaacctcagtagcagtggctacgcc accaacaaagagaaggagaggattgctagtctgttctgtaagctggcagctcttgtcaga cataggatttctctctttggtgcggattcacccacgatggtgagctgcctacacatcttg gcccattctctggacttcagaacggtgatgaagtcgggctcggagctggtgaaggccggg gtgcgggggttcttcgataacgcggcggaggacctggagaagaccatggagaacctgaag ctgggcaagcagacgcagcgcacccagatgaagggcgtgtcccagatcatcaactacacc atcacggccctgctgcccgtgctcaccgcgctcttccagcacgtgtcccaccaccatttt ggaggagatctgttattggatgacgtgcagctatccagttaccggatcctgaccagcctg tactctctgggcacggggaagaactcatacgttgagaagcagctgccaaccctgggcgag tgtttgtccactctggtgagcgccatgcccgtggccttcctggagacacacctggatgcg cacaaccccctgtccgtgttcaacaccaagacgccacgcgagagagccatcctgagcatg cccgatagcgtgacggagatgtgccccgagatgccggagctggacggcctgctgaaggac atcagcgacctgtccgagtcgggcgcccgctactccgacatgccgcaggtgatcgaggtg gtcctgcccatgctgtgcacctacctgtccacctggtgggacaagggcccggacaacaac agcggcagcagcggatgctgcaccagcgtctcgtccgagcacctcagcaccatgctgggc aacatcctccgcatcctcaacaacaacctgggcatcgacgaggcgccctggatgaagagg ctggcagttttcacccagccggtcatctgcaaggccgggtcggacctcctgaagagtcac ttcctgcccaccctggagaagatgaggaagaagacggtgaaggtggtctcggaggaggag gcgctgaaggccgacaccaagggcgacacgcaggagatggagctgcagatcctggacgag tttgccgtcctctgcagggacctgtacgccttctaccccatgctcatccgctacgtggac aacttcaggtccaaatggcttaaggagcctgacgatgactccactacgctctttaacatg gtcgctgagatctttatcctctggtgcaaatcccataatttcaagagggaggagcagaac tttgtggttcagaatgagatcaacaacctggccttcctgactgtggactccaagaccaag atggccaagtcgggaggcgaggaccaggagcgtaagggccggcggcggaagcgggagctg tactcggtgcagacctccctcatcgtggccgccctcaagaagctgctgcccatcggcctc aacatgtgcacgccgggcgagcaggagctcatcacgctggccaagatccgctacggcctg aaagacacagatgacgaggtcaaagaccatcttcgccagaaccttcaccttcaagagaag tcggatgacccggcggtgcagtggcaggtgaacctgtacaaggacgtggtggtgaagagc gaggggcctccggaccccgagcacatcgtcgtgagggtgcagggactctccgccgccctc ttccatctggacgcggtggagctgcccctaaggaataagaagaacttgacacagaagctg ctgtccaaacaacgcaagcgtgccgtggtggcctgcttccgcatggcccccctttacaac ttgcccaggcatcgctgtattaaccacttcttcctggcctatcagaggttctggatagag gcagaggagtacttttttgaggagaagctagtgcaggacctggccaaaaccccgataaag gtggcggatgaggaagaggaggaggaagcagaggtcaagcctgaccctctgcaccagctc atcctccacttcagtcacaatgctctcacggagaggagtcagctggatgaagatccgttg tatatagcatatgcagacatgatggcaaagagctgtgcagaagatgaggaggaggaggaa gacgaggaaggagccaagagctttgaggaaaaagagatggagaagcagaagatattgtac cagcaggcccggctccatgcccgtggggcagctgagatggtgctgcagatgatcagtgcc agtaaaggccgccttgggccaatggtgaccggaacactcaaactgggcatctcaattctg agtggtggtaatgtgattgtccagcagaaaatgctggactacctgaaactgaaaagagat gctggctttttcaaaagtttaactggactcatgcaagcttgcagtgtcctggatctgaat gcatttgagagacagaacaaagcagaaagcctaggaatgatgtctgaagaaggatcaatc aactcgagtgagaaggcttctaaagtgctgcagaatgacgacttcaccaaggatctgttt aggtttctgcagcttctctgtgagggccacaacgccgatttccagaatttcctccgtacc cagactggtaacaccaccacagtcaacatcatcatcagcactgtggactacctgctccgt ctgcaggagtccatcagcgatttctactggtactactctggaaaagatgttatggatgaa gctggccagtacaacttctccaaagcccttgctgtagcgaagcaggtgttcaactcactt actgagtacattcagggcccctgcatcggcaaccagcagagcttggcgcacagcaggctg tgggatgccgtggtgggattcctgcatgtgtttgccaacatgcagatgaagctttcacag gactcgagtcaaattgagctgttgaaggaattgatggatctacagaaagatatggtggtt atgatgctgtctctccttgagggtaacatagtgaatggaactattggaaaacagatggta gatacactggtggaatcttctagcaacgtagagatgatactcaagttctttgacatgttc ctcaaactaaaagaccttacgacctccgacaacttcaaggagtacgatcctgacagcaaa gggatcatatccaagaaggagtttcagaaggctatggagaaccaaaagcaatacatgcaa tcagagatcgacttcctcctctgttgtgcagaggccgacgagaacgacatgtttaactac gaggagttcgttgaccgctttcacgagcccgccaaagacatcggttttaacgtcgtcgtc ctgctcacgaacctgtccgagcacatgcctcatgacaaccgcctggccaccttcctcgac ctcgctgacagcgtcgtgaattacttcgagccatacctcggtcgcatcgagatcatgggt agtgccaagaggatcgagagggtctactttgagatcagcgagtcgagtcgcacacagtgg gaaaagccgcaggtcaaggagtccaagcgacagttcatcttcgacgtggtcaacgagggc ggcgagagcgagaagatggagatgtttgtcaacttctgcgaggacaccatctttgagatg cagctggcctcacagatctccgagccggaagttgtcgagcggcacgaggaagaggaggaa gaggaggacgagccggaagaggaagaggagggcgtggagtcccagtcggccttctcggcg gcttgcggctctgttaagcggaagatctccaacttccgtcagatgttgaccctacgcagc atgggcaagcagttcaaggcgatgaggaagctcaccatccgcgagatgatcgccggtttc ttcggcttcttctggatgctcttcaccggcttcttcaagggaatctacaacgtcatcttt ggcttcttccacatcatctggacgtccatctttggcgggggcctggtcgagggcgccaaa aacatcaaggtgaccgacatcctgggcaacatgcccgacccgactcagtttggaatccac ggcgacgttctagaggcggagaaggcggacatcggcgaaatggtggcggcggcggacatg gcgcagatggcgagcggcgagccggtggaggtggacgtgatgatggagctgatgggcggg gcggccaaacgggacgccaagcacgaactgggtctgggcgacgtctgcgagatcaagcct gccgagtccgccgcgccagagaagaagaagagcaagaaagctgaagtgaaggaatccgag ccagagaaagcagacacagagaatcaggagaaagaggagaaggccaaagaggaggtgcct gcggagccggcggcgaaggacaaacccgcccgtaagcccagacgtggtgccgatcaggag gagagccctgccttcatggccagcttcgtcgcaggcctggaggtctacaagaccaagatg ctgaactatctggctcgcaacttctacaaccttcgtatgctggctctgtttgtggccttt gccatcaacttcatcctcctgttctacaaggtgactgctgatgaggtggatgaggacgag gactcctgggaaaacggtgacgatgaagaggacgatgaggggctggagtactttgtgctt caggagagtaccggctacatggcacccacgttgaccttcctagcgctctcacacactctc atctccttgctgtgtgtcttgggatattactatctgaaggtccctctggtggtgttcaag agggagaaggagattgcgaggagtctggagtttgaaggcatctatatcaccgagcagcca tctgacgatgacatcaaaggacagtgggatcgattggttatcaacacaccatcttttccg agcaattactgggacaaatttatcaagagaaaggtcatcaataaatatggtgatttgtac ggagctgagcgcattgctgaactccttggcttggacaagagtgctctggactttgacccc acgatagagacagtggcacctgaggcctccctagtttcttggttgagttccattgacacc aagtatcatacttggaaaatgggcgtggttctgactgacaattccttcctgtatctggtg tggtacaccaccatgtcctccctgggtcactacaacaacttcttcttcgccgcccacttg ctggacatcgccatgtgcttcaagcctctgaggaccatcctgtcatccgtaacacacaat ggcaaacagctggtgctgaccgttgggctgttggccgtggtggtgtacctctacacagtc gtggccttcaacttcttccgcaagttctacaacaagagtgaagatgaggatgagcctgac atgaagtgtgacgatatgatgacttgctacttgttccacatgtacgtgggtgtcagggct ggcggcggcatcggtgatgagattgaagacccagccggggatccatctgaactttaccgt atcctcttcgacatcaccttcttcttcttcgtcatcgtcatcctgctggccattattcag ggtttgattattgacgcttttggagagctgagaggccagcaggaccaagtgaaggaggat atggagactaaatgtttcatctgtggaattggtaatgactacttcgacactacaccccat ggcttcgagacccacaccttacaagagcacaaccttgccaactacctgttcttcctgatg tatctgattaacaaggatgaaactgagcacacgggtcaggaatcatttgtgtggaagatg taccaagagagatgctgggacttcttcccagccggagactgtttccgcaagcaatatgag gaccagctaggctaa

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