Streptococcus pyogenes MGAS9429 (serotype M12): MGAS9429_Spy1788
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Entry
MGAS9429_Spy1788 CDS
T00358
Symbol
hutH
Name
(GenBank) histidine ammonia-lyase
KO
K01745
histidine ammonia-lyase [EC:
4.3.1.3
]
Organism
spk
Streptococcus pyogenes MGAS9429 (serotype M12)
Pathway
spk00340
Histidine metabolism
spk01100
Metabolic pathways
Module
spk_M00045
Histidine degradation, histidine => N-formiminoglutamate => glutamate
Brite
KEGG Orthology (KO) [BR:
spk00001
]
09100 Metabolism
09105 Amino acid metabolism
00340 Histidine metabolism
MGAS9429_Spy1788 (hutH)
Enzymes [BR:
spk01000
]
4. Lyases
4.3 Carbon-nitrogen lyases
4.3.1 Ammonia-lyases
4.3.1.3 histidine ammonia-lyase
MGAS9429_Spy1788 (hutH)
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Gene cluster
GFIT
Motif
Pfam:
Lyase_aromatic
Motif
Other DBs
NCBI-ProteinID:
ABF32975
UniProt:
Q1JJJ8
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Position
1739165..1740829
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AA seq
554 aa
AA seq
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MFMVQLVSSLQVVCTTLCTDVTTKWTKWTKCPLRNKSRRKTMTRVINLDGESLTIEDVIA
IARQGVACRIDDSAIEAVNASRKIVDDIVSEKRVVYGVTTGFGSLCNVSISPEDTVQLQE
NLIRTHASGFGDPLPEDAVRAIMLIRINSLVKGYSGIRLSTIEKLLELLNKGVHPYIPEK
GSLGASGDLAPLAHMVLPMLGLGKAYYKGELLSGQEALDKAGIDKISLAAKEGLALINGT
TVLTAIGALATYDAIQLLKLSDLAGALSLEVHNGITSPFEENLHTIRPQSGQLATARNIR
NLLEGSQNTTVATQSRVQDPYTLRCIPQIHGASKDSIAYVKSKVDIEINSVTDNPIICKD
GHVISGGNFHGEPMAQPFDFLGIAISEIGNVSERRVERLVNSQLSKLPSFLVKYPGLNSG
FMITQYACASLASENKVLAHPASVDSIPSCENQEDFVSMGTTAARKAFEILKNSRRIVAT
EIMAACQALDLKSENHELGKGTKVAYDLFRKEVNFIEHDKHIEIYDELNKASTVIEDPSF
LEAVEQTVELSIQF
NT seq
1665 nt
NT seq
+upstream
nt +downstream
nt
ttgtttatggtgcagttggtgtcatcattgcaagtagtgtgtactaccttatgcacggac
gtaaccaccaaatggaccaaatggaccaaatgccccctaaggaacaaatctaggagaaaa
actatgacaagagtgattaatttagatggcgaaagccttactatcgaagacgtgattgcg
attgctcgccaaggcgtagcctgtcgcattgatgatagtgctattgaagctgtgaatgcc
tctcgtaaaattgttgatgacattgtcagtgaaaaacgggtggtttacggggtgaccacc
ggttttggatccctttgtaacgtaagcatctcaccagaagatacagttcaactccaagaa
aatttgattcgtacccatgctagtggatttggtgacccattgccagaagatgccgtgaga
gctatcatgctgatccgtatcaactctctcgtcaaagggtattctggtattcgtctatcc
accattgaaaaactgttggaactgctcaataaaggggttcatccttacattcctgaaaaa
gggtctctaggggcttcaggagatttggcgccgcttgctcacatggtgcttcctatgctt
ggtctagggaaagcttactacaaaggagagcttctttctggtcaagaagctcttgataaa
gctggtattgacaagatttctttagccgctaaagaaggactcgcccttatcaacggaaca
actgttctcactgcaatcggtgcccttgcaacctatgacgccattcaattattgaaactg
tcagacctagctggtgccctatctcttgaagtgcataacgggattactagtccatttgaa
gaaaaccttcacaccattcgccctcaaagcggccagttggcaacagcccgcaatatccga
aacctcctagaaggtagccaaaacacaaccgtagctactcaatctcgtgtgcaagaccct
tacaccttgcgctgcatccctcaaattcatggggctagcaaagacagtatcgcctatgtc
aaatccaaagttgacattgaaatcaattctgtcacagataatccaattatctgtaaagat
ggccacgttatttcaggaggtaacttccacggagaaccaatggcacagccatttgacttc
ttaggcatcgccatttctgaaattggaaatgtttctgaacgccgcgtggaacgtttggtc
aatagccagctcagcaaattgccatccttccttgtcaaatacccaggtctcaattcaggc
tttatgattacccagtacgcctgtgcctctcttgcttctgaaaacaaggttttggcacat
ccagccagtgtggattctatcccatcttgtgagaaccaagaagactttgtcagcatgggc
accaccgctgctcgcaaggcctttgaaatccttaaaaattctcgccgcatcgtggctact
gaaatcatggcagcctgccaagcccttgatctcaaatctgaaaatcatgaactaggtaaa
gggactaaggttgcctacgatctcttccgcaaggaagtcaactttatcgaacacgataaa
cacatcgaaatctacgatgaactaaacaaggcatcaacagtcattgaagacccaagcttc
ctcgaagcggttgagcagacagttgagttgagtatccaattttag
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