KEGG   Streptococcus pneumoniae TIGR4 (virulent serotype 4): SP_0447
Entry
SP_0447           CDS       T00057                                 
Symbol
ilvC
Name
(GenBank) ketol-acid reductoisomerase
  KO
K00053  ketol-acid reductoisomerase [EC:1.1.1.86]
Organism
spn  Streptococcus pneumoniae TIGR4 (virulent serotype 4)
Pathway
spn00290  Valine, leucine and isoleucine biosynthesis
spn00770  Pantothenate and CoA biosynthesis
spn01100  Metabolic pathways
spn01110  Biosynthesis of secondary metabolites
spn01210  2-Oxocarboxylic acid metabolism
spn01230  Biosynthesis of amino acids
Module
spn_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
spn_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:spn00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    SP_0447 (ilvC)
  09108 Metabolism of cofactors and vitamins
   00770 Pantothenate and CoA biosynthesis
    SP_0447 (ilvC)
Enzymes [BR:spn01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.86  ketol-acid reductoisomerase (NADP+)
     SP_0447 (ilvC)
SSDB
Motif
Pfam: KARI_N KARI_C 2-Hacid_dh_C F420_oxidored AdoHcyase_NAD NAD_binding_2 ApbA DUF1103 NAD_Gly3P_dh_N CoA_binding TrkA_N DUF7779
Other DBs
NCBI-ProteinID: AAK74608
UniProt: Q97SD7
LinkDB
Position
419696..420706
AA seq 336 aa
MEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDVIIGVRPGKSFDKAKEDGFDT
YTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGNAVGFAHGFNIHFEFIKVPADVD
VFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGNAKNIAMDWCKGVGAARVGLLETTY
KEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAGYAPELAYFEVLHEMKLIVDLIYEGGF
KKMRQSISNTAEYGDYVSGPRVITEQVKENMKAVLADIQNGKFANDFVNDYKAGRPKLTA
YREQAANLEIEKVGAELRKAMPFVGKNDDDAFKIYN
NT seq 1011 nt   +upstreamnt  +downstreamnt
atggaatatgaaaaagatgttaaagtagcagcacttgacggtaaaaaaatcgccgttatc
ggttatggttcacaagggcatgcgcatgctcaaaacttgcgtgattcaggtcgtgacgtt
attatcggtgtacgtccaggtaaatcttttgataaagcaaaagaagatggatttgatact
tacacagtagcagaagctactaagttggctgatgttatcatgatcttggcgccagacgaa
attcaacaagaattgtacgaagcagaaatcgctccaaacttggaagctggaaacgcagtt
ggatttgcccatggtttcaacatccactttgaatttatcaaagttcctgcggatgtagat
gtcttcatgtgtgctcctaaaggaccaggacacttggtacgtcgtacttacgaagaagga
tttggtgttccagctctttatgcagtataccaagatgcaacaggaaatgctaaaaacatt
gctatggactggtgtaaaggtgttggagcggctcgtgtaggtcttcttgaaacaacttac
aaagaagaaactgaagaagatttgtttggtgaacaagctgtactttgtggtggtttgact
gcccttatcgaagcaggtttcgaagtcttgacagaagcaggttacgctccagaattggct
tactttgaagttcttcacgaaatgaaattgatcgttgacttgatctacgaaggtggattc
aagaaaatgcgtcaatctatttcaaacactgctgaatacggtgactatgtatcaggtcca
cgtgtaatcactgaacaagttaaagaaaatatgaaggctgtcttggcagacatccaaaat
ggtaaatttgcaaatgactttgtaaatgactataaagctggacgtccaaaattgactgct
taccgtgaacaagcagctaaccttgaaattgaaaaagttggtgcagaattgcgtaaagca
atgccattcgttggtaaaaacgacgatgatgcattcaaaatctataactaa

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