Sporosarcina sp. PTS2304: DV702_11545
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Entry
DV702_11545 CDS
T05572
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
spos
Sporosarcina sp. PTS2304
Pathway
spos00300
Lysine biosynthesis
spos00550
Peptidoglycan biosynthesis
spos01100
Metabolic pathways
spos01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
spos00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
DV702_11545
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
DV702_11545
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
DV702_11545
Enzymes [BR:
spos01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
DV702_11545
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
AXI00294
UniProt:
A0A345NZ35
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Position
complement(2422240..2423622)
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AA seq
460 aa
AA seq
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MEDSYVKRNLSTIQQWLQAAGQEIEQQQITGVCIDSRNVQKGDLFIPFRGEQVNGHQYVT
GAIEKGAAASLWLKDEPNPPEGIPLLFVDDAEVALQQMARMYRQELHCTVIGVTGSNGKT
STKDLLAGVLSPYFKVKKTEGNFNNELGLPLTLLAVEDDTEVAILEMGMSGFGEISFLST
LASPHFAVITNIGEAHMQDLGSREGIAKAKFEIIDGLAIDGLLLYDGDEPLLRELVASQP
QVRTISFGYERADVTVAHIQSTSIGSSFTVQGRTEGEFVIPVYGAHQVKNTLAAIIIAKE
LGLTEAQIKSSLEQTKLTDMRMQPMTGINDSLLINDAYNAAPTSMRAAFRFMQETNVRKD
KWLVLGDMLELGSDEQSYHEGLADDLRKMDLQGVILFGSRMKWLADRLTEYPLEVMWTAT
DVQLAVDALRPRLTQDTVVLFKGSRGMKLERIMGPLEETL
NT seq
1383 nt
NT seq
+upstream
nt +downstream
nt
gtggaggattcttacgtgaaacgaaatttatcaacgattcaacagtggttacaggcggca
ggtcaagaaatcgaacagcaacaaataacgggtgtttgtatcgattctcgcaacgtacaa
aaaggcgatctctttatacctttccgcggagaacaagtcaatggtcatcaatacgttaca
ggtgcgattgaaaagggcgcagcagcgtcactttggctaaaagatgaacccaatccgcca
gaaggcatcccgcttttatttgtcgacgatgcagaagtcgcattgcaacagatggctcgc
atgtatcgccaagaattacattgtaccgttatcggtgtcacaggctctaatggaaaaaca
tcgacgaaagatttactggcaggagtattgtcaccttatttcaaagtgaaaaagacagaa
ggcaattttaataacgagttaggattgcctctgacgctattagctgtggaagacgacaca
gaagttgcgattcttgaaatgggaatgagtggttttggcgaaatttccttcctctctacc
ctcgcctcgccgcattttgcagttattacgaatatcggggaagcacatatgcaagatctc
gggtctagagaggggattgcgaaagcgaaatttgaaatcatagatgggttagcgatagat
ggtttactcctttacgatggcgatgaaccgttactgcgtgagttagtagctagtcagccg
caagtgcgtactatatcgttcggctatgagcgggcagatgtaaccgtagctcacattcaa
tccacgagcataggcagctcatttactgtgcaaggcagaacggaaggggagtttgtgatt
ccggtgtacggcgcacatcaagtgaaaaacacattagctgcgattatcattgcgaaagag
cttggattgactgaagcgcaaattaaatcatcattagaacagacaaagctaacggatatg
cgtatgcaaccaatgaccggaatcaatgactctcttctaatcaatgatgcttataatgca
gcaccgacttcgatgagagccgcttttcgatttatgcaagagacaaacgtacgcaaagac
aaatggcttgttttaggggatatgcttgaacttggatctgatgagcaaagctatcatgaa
ggactggcagatgatttacgtaaaatggatctgcaaggggtaattcttttcggaagtcgc
atgaaatggctagctgaccgactgacagagtatcctctagaagtgatgtggacagcaact
gacgtgcagttggcggtagatgcactgcgtccgcgattgactcaagatactgttgtctta
tttaaagggtcgcgtggcatgaaattagagcgcatcatgggtccgcttgaggaaacgttg
tga
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