Symphalangus syndactylus (siamang): 129466042
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Entry
129466042 CDS
T10134
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
ssyn Symphalangus syndactylus (siamang)
Pathway
ssyn00260
Glycine, serine and threonine metabolism
ssyn00630
Glyoxylate and dicarboxylate metabolism
ssyn00670
One carbon pool by folate
ssyn01100
Metabolic pathways
ssyn01200
Carbon metabolism
ssyn01230
Biosynthesis of amino acids
ssyn01240
Biosynthesis of cofactors
ssyn01523
Antifolate resistance
ssyn04981
Folate transport and metabolism
Module
ssyn_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
ssyn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
129466042 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
129466042 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
129466042 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
129466042 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
129466042 (SHMT2)
Enzymes [BR:
ssyn01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
129466042 (SHMT2)
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GFIT
Motif
Pfam:
SHMT
Motif
Other DBs
NCBI-GeneID:
129466042
NCBI-ProteinID:
XP_055104889
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All DBs
Position
17:complement(32548346..32556585)
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AA seq
513 aa
AA seq
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MSGVFGLASQAEPFRPALSPADDATEPHCLHQAGVPAAVRAGRRWNGLCRDVGSWSGWPF
GLSTARQPRLRLGKQTGAGQARRACRRVILRCGSCCRGRRTGSVVAWSSLPQRYYGGAEV
VDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGH
LTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYDQLALTARLFRPRLIIAGTSAYARL
IDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIF
YRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYS
LQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNT
CPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVDIGLEVKSKTAKLQDFKSF
LLKDSETSQRLADLRQRVEQFARAFPMPGFDEH
NT seq
1542 nt
NT seq
+upstream
nt +downstream
nt
atgagcggagttttcggcctggcctcacaagctgagcctttccggccagctctgagccct
gcagatgatgcaaccgagcctcactgcttgcatcaggcaggggtcccggcggcagtgagg
gctggaaggaggtggaacggcctttgcagagatgtgggcagctggtcaggatggccattc
gggctcagcacagcaaggcagcccagactcagactggggaagcaaacaggggctggacag
gccaggagagcctgtcggagagtgatcctgagatgtgggagttgctgcagagggagaagg
acaggcagtgtcgtggcctggagctcattgcctcagagatactatgggggagcagaagtg
gtggatgaaattgagctgctgtgccagcgccgggccttggaagcctttgacctggatcct
gcacagtggggagtcaatgtccagccctactccgggtccccagccaacctggccgtctac
acagcccttctgcaacctcacgaccggatcatggggctggacctgcccgatgggggccat
ctcacccacggctacatgtctgacgtcaagcggatatcagccacgtccatcttcttcgag
tctatgccctataagctcaaccccaaaactggcctcattgactatgaccagctggcactg
actgctcgacttttccgaccgcggctcatcatagctggcaccagcgcctatgctcgcctc
attgactatgcccgcatgagagaggtgtgtgatgaagtcaaagcacacctgctggcagac
atggcccacatcagtggcctggtggctgccaaggtgattccctcgcctttcaagcatgcg
gacattgtcaccaccactactcacaagactcttcgaggggccaggtcagggctcatcttc
taccggaaaggggtgaaggctgtggaccccaagactggccgggagatcccttacacattt
gaggaccgaatcaactttgccgtgttcccatccctgcaagggggcccccacaatcatgcc
attgctgcagtagctgtggccctaaagcaggcctgcacccccatgttccgggagtactcc
ctgcaggttctgaagaatgctcgggccatggcagatgccctgctagagcgaggctactca
ctggtatcaggtggtactgacaaccacctggtgctggtggacctgcggcccaagggcctg
gatggagctcgggctgagcgggtgctagagcttgtatccatcactgccaacaagaacacc
tgtcctggagaccgaagtgccatcacaccggggggcctgcggcttggggccccggcctta
acttctcgacagttccgtgaggatgacttccggagagttgtggactttatagatgaaggg
gtcgacattggcttagaggtgaagagcaagactgccaagctccaggatttcaaatccttc
ctgctcaaggactcagaaacaagtcagcgtctggccgacctcaggcaacgggtggagcag
tttgccagggccttccccatgcctggttttgatgagcattga
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