KEGG   Streptomyces tirandamycinicus: DDW44_21640
Entry
DDW44_21640       CDS       T06843                                 
Name
(GenBank) ketol-acid reductoisomerase
  KO
K00053  ketol-acid reductoisomerase [EC:1.1.1.86]
Organism
stir  Streptomyces tirandamycinicus
Pathway
stir00290  Valine, leucine and isoleucine biosynthesis
stir00770  Pantothenate and CoA biosynthesis
stir01100  Metabolic pathways
stir01110  Biosynthesis of secondary metabolites
stir01210  2-Oxocarboxylic acid metabolism
stir01230  Biosynthesis of amino acids
Module
stir_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
stir_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:stir00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    DDW44_21640
  09108 Metabolism of cofactors and vitamins
   00770 Pantothenate and CoA biosynthesis
    DDW44_21640
Enzymes [BR:stir01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.86  ketol-acid reductoisomerase (NADP+)
     DDW44_21640
SSDB
Motif
Pfam: KARI_N KARI_C F420_oxidored 2-Hacid_dh_C NAD_binding_2 AdoHcyase_NAD PDH_N NAD_Gly3P_dh_N CoA_binding Rossmann-like ApbA NAD_binding_7 GFO_IDH_MocA DUF1103
Other DBs
NCBI-ProteinID: AWI31091
UniProt: A0A2S1SXI2
LinkDB
Position
4885712..4886713
AA seq 333 aa
MAELFYDDDADLSIIQGRKVAVIGYGSQGHAHALSLRDSGVDVRVGLHEGSKSKAKAEEQ
GLRVVTPSEAAAEADVIMILVPDPIQAQVYEESVKDNLKDGDALFFGHGLNIRYGFIKPP
AGVDVALVAPKGPGHLVRRQYEEGRGVPCIAGVEQDATGNAFALALSYAKGIGGTRAGVI
KTTFTEETETDLFGEQAVLCGGTAALVKAGFETLVEAGYQPEIAYFECLHELKLIVDLMY
EGGLEKMRWSVSETAEWGDYVTGPRIITDQTKAEMKKVLDEIQDGTFAKNWMDEYHGGLK
KYNEYKTQDENHLLETTGKELRKLMSWVDAEEA
NT seq 1002 nt   +upstreamnt  +downstreamnt
gtggccgagctgttctacgacgacgacgccgacctgtccatcatccagggccgcaaggtc
gcggtcatcggctacggcagccagggccacgcccacgcgctgtcgctgcgtgactccggt
gtggacgtccgcgtcggtctgcacgagggctccaagtccaaggccaaggccgaggagcag
ggcctgcgcgtggtgacgccgtcggaggccgccgccgaggccgacgtcatcatgatcctg
gtcccggacccgatccaggcccaggtctacgaggagtccgtcaaggacaacctcaaggac
ggcgacgcgctgttcttcggccacggcctcaacatccggtacggcttcatcaagcccccg
gccggcgtggacgtcgcgctcgtcgcccccaagggccccggccacctggtgcgccgccag
tacgaggagggccgcggcgtcccgtgcatcgccggtgtcgagcaggacgcgaccggcaac
gccttcgcgctggcgctctcgtacgccaagggcatcggcggcacccgtgccggcgtcatc
aagaccaccttcaccgaggagaccgagaccgacctgttcggtgagcaggccgtgctctgc
ggcggcaccgccgcgctggtcaaggcgggcttcgagaccctggtcgaggcgggctaccag
ccggagatcgcctacttcgagtgcctccacgagctgaagctgatcgtggacctcatgtac
gagggcggcctggagaagatgcgctggtccgtctccgagaccgccgagtggggcgactac
gtgaccggcccgcgcatcatcacggaccagaccaaggccgagatgaagaaggtcctcgac
gagatccaggacggcaccttcgccaagaactggatggacgagtaccacggcggcctgaag
aagtacaacgagtacaagacgcaggacgagaaccacctgctggagaccaccggcaaggag
ctccgcaagctcatgagctgggtggacgccgaggaggcgtga

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