Streptomyces sp. WP-1: QHG49_04820
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Entry
QHG49_04820 CDS
T10379
Symbol
metE
Name
(GenBank) 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase
KO
K00549
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:
2.1.1.14
]
Organism
strw Streptomyces sp. WP-1
Pathway
strw00270
Cysteine and methionine metabolism
strw00450
Selenocompound metabolism
strw01100
Metabolic pathways
strw01110
Biosynthesis of secondary metabolites
strw01230
Biosynthesis of amino acids
Module
strw_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
strw00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
QHG49_04820 (metE)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
QHG49_04820 (metE)
Enzymes [BR:
strw01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.14 5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
QHG49_04820 (metE)
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GFIT
Motif
Pfam:
Meth_synt_2
Meth_synt_1
B12-binding
Motif
Other DBs
NCBI-ProteinID:
WKE68396
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Position
1166148..1168466
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AA seq
772 aa
AA seq
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MTTKSAAAAARATVYGYPRQGANRELKKAIEGYWKGRVSADELRATAAELRGTAWRRLAE
AGLHEVPSGDFSYYDHVLDTSVMVGAIPDRHRAAVAADPLDGYFAMARGTQEVAPLEMTK
WFDTNYHYLVPELGPDTVFTADSAKQVAELTEALALGLSARPVLVGPVTYLLLAKPAPGV
PADFEPLTLLDRLLPVYAEVLADLRAAGADWVQLDEPALVQDRTPAELNAAERAYRDLGA
LTDRPRLLVASYFDRLGEALPVLAKAPVEGLALDFTEAAARNLDALAAVGGLPGKRLVAG
VVNGRNVWVDDLEKSLATLGTLLGLADRVDVSASCSLLHVPLDAAAEHDIDPQIRRWLAF
AEQKTAELATLAKGLTLGTDAIAAELSANRADLASRAGSALTHDPAVRARAAAVTEADAR
RSQPYAERAAAQRARLGLPLLPTTTIGSFPQTGELRAARADLRAGRIDTAGYEERVRAEI
REVIAFQEKAGLDVLVHGEAERNDMVQYFAEQLTGYLATQHGWVQSYGTRYVRPPILAGD
ISRPGPMTVRWTSYAQSLTDRPVKGMLTGPVTMLAWSFVRDDQPLGDTARQVALALRDEV
DDLEHAGTSVIQVDEPALRETLPLRAADRPAYLDWATEAFRLSTCGVRPDTQIHTHMCYA
EFGDIVRAIDDLDADVISLEAARSHMQVARELAAHGYSREAGPGVYDIHSPRVPSAEEAA
GLLRTGLGAIPAERLWVNPDCGLKTRGWPETRESLENLVAAARTVRAELAGA
NT seq
2319 nt
NT seq
+upstream
nt +downstream
nt
gtgaccacgaagtccgcagccgcggcggcacgggccaccgtgtacggctacccccgccag
ggggcgaaccgggaactgaagaaggcgatcgagggctactggaagggccgcgtcagcgct
gacgaactgcgggcgaccgcagccgagttgcgcggcaccgcctggcgccggctcgccgag
gccggtctgcacgaggtgccgtccggcgacttctcgtactacgaccatgtcctggacacc
agcgtcatggtcggcgcgatccccgaccggcaccgggcggccgtcgccgccgatccgctg
gacggctacttcgcgatggcccgcggcacccaggaggtggcgccgctggagatgaccaag
tggttcgacaccaattaccactatctggtacccgagttggggccggacacggtgttcacg
gccgactccgccaagcaggtcgcggagctgaccgaggccctcgccctcgggctgagcgcc
cgcccggtgctggtgggcccggtgacctatctgctgctggccaagcccgcgcccggggtg
cccgccgacttcgagccgctgaccctgctggaccggctgctgccggtgtacgccgaggtc
ctcgccgacctgcgggcggccggcgccgactgggtgcagctcgatgagcccgccctcgtc
caggaccgcaccccggccgagctgaacgccgccgagcgcgcctaccgcgatctcggcgcc
ctcaccgaccggcccaggctgctggtggcgtcctacttcgaccggctcggcgaggccctg
ccggtgctcgcgaaggcgccggtggagggcctggccctggacttcaccgaggccgccgcc
cggaacctggacgcgctggccgccgtcggcgggctgcccggcaagcggctggtcgcgggc
gtcgtcaacggccgcaacgtctgggtcgacgacctggagaagtccctggccaccctcggc
accctgctgggcctggccgaccgggtcgacgtctcggcctcctgctccctgctgcacgtc
cccctcgacgcggccgccgagcacgacatcgacccgcagatccggcgctggctcgccttc
gccgagcagaagacggcggaactcgccacgctggccaagggcctcaccctcggcacggac
gccatcgccgcggagctgtccgcgaaccgggccgacctcgcctcccgggccggttccgcc
ctcacccacgaccctgccgtgcgcgcccgcgccgccgccgtcaccgaggccgatgcccgc
cgctcccagccgtacgccgagcgcgccgccgcccagcgcgcccggctggggctgcccctg
ctgcccacgacgacgatcggctcgttcccgcagaccggtgaactgcgcgccgctcgcgcc
gacttgcgggcgggccggatcgacaccgccgggtacgaggagcgcgtgcgggccgagatc
cgggaggtgatcgccttccaggagaaggccgggctcgacgtcctggtgcacggcgaggcc
gaacgcaacgacatggtccagtacttcgccgaacagctcaccggctacctcgccacccag
cacggctgggtccagtcgtacggcacccggtacgtgcggccgccgatcctggccggcgac
atctcccgccccggtccgatgacggtccgctggacgtcgtacgcccagtcgctcacggac
cgcccggtcaagggcatgctcaccggtccggtcaccatgctcgcctggtccttcgtccgc
gacgaccagcccctcggggacaccgcgcggcaggtcgccctcgcgctgcgggacgaggtc
gacgaccttgagcacgcggggacttcggtgatccaggtggacgagcccgcgctgcgcgag
acgctgccactgcgcgccgccgaccggcccgcgtacctggactgggcgaccgaggcgttc
cggctgagcacctgcggggtgcgcccggacacccagatccacacccatatgtgctacgcc
gagttcggtgacatcgtgcgcgccatcgacgatctcgacgccgatgtcatcagcctggag
gcggcccgctcccatatgcaggtcgcccgcgaactggccgcccacggctattcacgcgag
gccggtcctggtgtctacgacatccactccccgcgcgtcccgagcgccgaggaggcggcc
gggctgctgcgcacggggctcggcgccatcccggccgagcggctgtgggtcaaccccgac
tgcggcctgaagacccgtggctggccggagacccgtgagtccctggagaacctggtcgcg
gccgcgcgcacggtccgcgcggagctggccggagcctga
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