Streptomyces sp. TN58: BSL84_23895
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Entry
BSL84_23895 CDS
T09761
Name
(GenBank) D-alanine--D-alanine ligase A
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
sttn
Streptomyces sp. TN58
Pathway
sttn00470
D-Amino acid metabolism
sttn00550
Peptidoglycan biosynthesis
sttn01100
Metabolic pathways
sttn01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sttn00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
BSL84_23895
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
BSL84_23895
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
BSL84_23895
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
sttn01011
]
BSL84_23895
Enzymes [BR:
sttn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
BSL84_23895
Peptidoglycan biosynthesis and degradation proteins [BR:
sttn01011
]
Precursor biosynthesis
Amino acid ligase
BSL84_23895
BRITE hierarchy
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp
ATP-grasp_4
ATP-grasp_3
Motif
Other DBs
NCBI-ProteinID:
APU42366
LinkDB
All DBs
Position
5219049..5220206
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AA seq
385 aa
AA seq
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MSSENLPQTPEQQGRKPRVAVVFGGRSSEHAISVVTAGAVLRSIDRSKYEVLPIGITTDG
RWALTADEPARMAIADRRLPSVEELAESEDGAVVLSVDPASRQVVYTEPGAVPKALGEVD
VVFPVLHGPYGEDGTLQGLLELSGIPYVGSGVLASAVGQDKDYMKRVFTSFGLSVGPYVT
IRPREWEADRDAATARILDFAAEHGWPLFVKPARAGSSIGITKVDDASGLEAAVKEARRH
DPKIIVEALLRGREIECGVLEFEDGPRASVPAEIPPVSSHDFYDFEAKYIDSASGIVPAP
LTPEQTAEVQRLAVEAFEAASCEGLVRADFFLTEDGEFVINEINTMPGFTPISMYPLMWE
KTGIAYPELVDRLIQAALRRSTGLR
NT seq
1158 nt
NT seq
+upstream
nt +downstream
nt
atgagcagcgagaacctcccccagacccctgagcagcagggccgcaagccccgcgtggcc
gtcgtgttcggcggccgcagctcggaacacgccatctcggtcgtcacggcgggcgccgta
ctgcgctccatcgaccggtccaagtacgaggtgctgcccatcggcatcaccacggacggc
cggtgggcgctgaccgccgacgagcccgcgcggatggccatcgcggaccgcaggctcccg
agcgtcgaggagctcgccgagtccgaggacggcgccgtggtgctctcggtcgacccggcc
agccgccaggtcgtctacaccgagccgggcgccgtcccgaaggccctgggcgaggtcgac
gtcgtcttccccgtgctgcacggcccctacggcgaggacggcaccctccagggcctcctg
gagctctccggcatcccgtacgtcggctcgggcgtcctcgcctcggccgtcgggcaggac
aaggactacatgaagcgggtgttcacgtccttcgggctgagtgtcggcccgtacgtgacc
atccgcccccgcgagtgggaggccgaccgggacgccgccaccgccaggatcctggacttc
gccgccgagcacggctggccgctcttcgtgaagcccgcccgggccggctcctcgatcggc
atcaccaaggtcgacgacgcctccggcctggaggccgccgtcaaggaggcccggcgccac
gacccgaagatcatcgtggaggcgctgctgcgcggccgcgagatcgagtgcggcgtcctg
gagttcgaggacgggccgcgggccagcgtccccgccgagatcccgccggtgtccagccac
gacttctacgacttcgaggcgaagtacatcgactccgcctccgggatcgtgccggccccc
ctcaccccggagcagaccgccgaggtgcagcggctcgcggtcgaggccttcgaggccgcg
tcctgcgagggcctcgtgcgcgccgacttcttcctcaccgaggacggcgagttcgtcatc
aacgagatcaacaccatgcccggtttcacgccgatctcgatgtacccgctcatgtgggag
aagaccggcatcgcctacccggagctggtggaccggctgatccaggccgccctgcgccgc
tccaccggcctgcgctag
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