Subtercola sp. PAMC28395: KPL76_12110
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Entry
KPL76_12110 CDS
T07261
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
subt
Subtercola sp. PAMC28395
Pathway
subt00010
Glycolysis / Gluconeogenesis
subt00020
Citrate cycle (TCA cycle)
subt00620
Pyruvate metabolism
subt00785
Lipoic acid metabolism
subt01100
Metabolic pathways
subt01110
Biosynthesis of secondary metabolites
subt01120
Microbial metabolism in diverse environments
subt01200
Carbon metabolism
subt01210
2-Oxocarboxylic acid metabolism
Module
subt_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
subt00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
KPL76_12110 (aceE)
00020 Citrate cycle (TCA cycle)
KPL76_12110 (aceE)
00620 Pyruvate metabolism
KPL76_12110 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
KPL76_12110 (aceE)
Enzymes [BR:
subt01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
KPL76_12110 (aceE)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_N
Transketolase_C
Transket_pyr
Motif
Other DBs
NCBI-ProteinID:
QWT25431
UniProt:
A0A975SKP2
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Position
2638420..2641152
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AA seq
910 aa
AA seq
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MTVNDQDPYSVSNIDSDPDETAEWSESLDALVAERGHGRAREIVLSLLKRSKELHLGVPM
VPTTDYINTIASENEPEFPGDEDIERRYRAWIRWNAAMLVHRAQRPGIAVGGHISTYASS
ASLYEVGFNHFFRGHDHPGGGDQVFVQGHASPGTYARAFLEGRLSEHQLDGFRQEKSHAG
GGLSSYPHPRLMPEFWQFPTVSMGIGPINAIYQAQSNKYLTNRGIKDASDQQVWAFLGDG
EMDEVESRGQLQVAANEGLDNLNFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIK
VIWGREWDSLLQNDSDGALLNLMNQTPDGDFQTYKTEDGKYVRDNFFGRDPRALKLVEDY
SDDQIWGLKRGGHDYRKVYAAFKAASEHKGQPTVILAHTIKGYGLGKGFAGRNATHQMKK
MSLPDLKAFRDEMRIPITDAQLEANDHWSPPYYNPGPDDEAIQYLHERRRALGGYVPERR
TKHTAITLPDDSAYAIMKKGSGTQEIASTMAFVRLLKEMTRSKDFGNRVVPVIPDEARTF
GMDAFFPSAKIYNPNGQHYTSVDRDLLLAYKESPQGQIIHVGINEAGAVAAFTAAGTSYA
TQGEPLIPVYVFYSMFGFQRTGDALWAAGDQMTRGFIMGATAGRTTLTGEGLQHADGHSH
LLAASNPAVISYDPAYGYEIGHIVRSGLERMYGGTHTDPNVMYYITLYNEPMVMPAEPEN
VDIEGIVKGIHHLKSGWVDNGPKANILASGVGVPWALEAQELLANDWGVSADVWSVTSWT
ELRRDGLRAEEHNFLYPNDERHVPYLTNKLSGAHGPFVAVSDYMHAVTDQIRQFVPGEYA
TLGADDFGFSDTRPAARRFFKIDGPSVVVRVLEQLAARGEVDQNAPQWAIEKYRLHDVSA
GTSGSAGGES
NT seq
2733 nt
NT seq
+upstream
nt +downstream
nt
ttgacagtcaacgaccaagacccctattcggtgtcgaacatcgattctgatcctgacgaa
acagccgaatggtctgagtcgctcgatgcactggttgccgagcggggccatggccgtgcc
agggagatcgtgctcagcctgctcaagcgcagcaaagaactgcaccttggcgtgccgatg
gttcccaccactgactacatcaacacgatcgcgtcagagaacgagcccgagttcccgggt
gacgaagacatcgagcgtcggtaccgtgcctggatccgctggaacgccgcgatgctggtg
caccgcgcacagcgccccggtatcgccgtcggtgggcacatctcgacctacgcatcgagc
gcgagcctctacgaagtcggtttcaaccacttcttccgcggccacgaccacccgggtggc
ggcgaccaggtcttcgtgcagggccacgcctcccccggcacctatgcccgtgcctttctc
gaaggccgtctcagcgagcaccagctcgacggattccgccaggagaagtcgcacgccggt
ggcggcctcagctcctacccccacccccggctcatgcccgagttctggcagttcccgact
gtgtcgatgggtatcggcccgatcaacgccatctaccaggcgcagtcgaacaagtacctc
accaaccggggcatcaaagacgccagcgaccagcaggtctgggcgttcctcggcgacggc
gagatggacgaggtcgagagccgtggccagctccaggtggctgccaacgagggtctcgac
aacctgaacttcgtgatcaactgcaacctgcagcgcctcgacggccctgttcgcggcaac
ggcaagatcatccaggagctcgagagcttcttccggggtgccggctggaacgtcatcaag
gtcatctggggccgcgaatgggattcgctgctgcagaacgactccgacggcgcgcttctc
aacctgatgaaccagactccggatggcgacttccagacgtacaagaccgaagacggcaag
tacgtccgggacaacttcttcggtcgcgatccccgggcgctgaagctcgtcgaagactac
agcgacgaccagatctggggcctcaagcgaggcggccacgactaccgcaaggtgtacgcc
gccttcaaggccgcgagcgagcacaagggccagcccacggtcatcctggcgcacaccatc
aagggctacggcctcggcaagggcttcgccggccgcaacgccacgcaccagatgaagaag
atgtcactgcccgacctcaaggcgttccgcgacgagatgcgcatcccgatcaccgacgcg
cagctcgaggcgaacgaccactggtctcccccgtactacaacccgggccccgacgacgaa
gcgatccagtacctgcatgagcgccgccgcgcgctcggcggctacgtgccggaacgccgc
acgaagcacaccgcgatcacgcttcccgacgactcggcctacgcgatcatgaagaagggc
tccggcacgcaggagatcgcctcgacgatggccttcgtgcgcctgctgaaggagatgaca
cggtcgaaggacttcggcaaccgtgtcgttcccgtcatccccgacgaggcacgaaccttc
ggaatggacgcgttcttcccgagcgcgaagatctacaacccgaacggccagcactacacc
agcgtcgaccgcgacctgttgctggcctacaaggagagcccacaggggcagatcatccat
gtcggaatcaacgaggccggtgccgtcgcagcattcaccgccgccggaacctcgtacgcc
acgcagggcgagcccctcatcccggtgtacgtcttctactcgatgttcgggttccagcgc
acaggtgacgcgctctgggccgcaggcgaccagatgacccgcgggttcatcatgggcgcg
acggcgggccgcaccacgctgacaggcgaaggcctccagcacgccgacggccattcgcac
ctgctcgcagcgagcaaccctgctgtgatctcgtacgacccggcctacggctacgagatc
ggccacatcgttcgctcggggctcgagcgcatgtacggcggcacgcacaccgacccgaac
gtcatgtactacatcacgctctacaacgagccgatggtcatgccggccgagccggagaac
gtcgacattgaaggcatcgtcaagggcatccaccacctcaagtcgggctgggtcgacaac
gggccgaaggcgaacatcctggcctccggcgtcggtgttccgtgggccctcgaagcccag
gaactgctggcaaacgactggggtgtctcggcagacgtctggtcggtcaccagctggacc
gagcttcgccgcgacggcctgcgggcagaggaacacaacttcctctaccccaacgacgag
cgccacgtgccgtacctcacgaacaagctgtcgggtgcccacgggcccttcgtcgctgtg
agtgactacatgcacgcggtcaccgaccagatcaggcagttcgtgcccggtgagtacgcg
actctgggcgccgacgacttcggattctccgacacccgccccgcagcccgccgtttcttc
aagatcgacggccctagcgttgttgtgcgtgttctggaacagctcgccgcccgcggtgag
gtcgaccagaacgcaccgcagtgggccatcgagaagtaccggctgcacgacgtgtctgct
ggtacctccggctccgccggcggagagagctga
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