KEGG   Staphylococcus aureus subsp. aureus JKD6008 (MRSA/VISA): SAA6008_00746
Entry
SAA6008_00746     CDS       T01886                                 
Symbol
nrdE
Name
(GenBank) ribonucleoside-diphosphate reductase, alpha subunit
  KO
K00525  ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
Organism
suk  Staphylococcus aureus subsp. aureus JKD6008 (MRSA/VISA)
Pathway
suk00230  Purine metabolism
suk00240  Pyrimidine metabolism
suk01100  Metabolic pathways
suk01232  Nucleotide metabolism
Module
suk_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
Brite
KEGG Orthology (KO) [BR:suk00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    SAA6008_00746 (nrdE)
   00240 Pyrimidine metabolism
    SAA6008_00746 (nrdE)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:suk03400]
    SAA6008_00746 (nrdE)
Enzymes [BR:suk01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1  ribonucleoside-diphosphate reductase
     SAA6008_00746 (nrdE)
DNA repair and recombination proteins [BR:suk03400]
 Prokaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    SAA6008_00746 (nrdE)
SSDB
Motif
Pfam: Ribonuc_red_lgC RNR_N Ribonuc_red_lgN UvrB_inter RNR-II_ins_dom Caud_tail_N
Other DBs
NCBI-ProteinID: ADL64805
LinkDB
Position
808581..810677
AA seq 698 aa
MEEKKYNHIELNNEVTKRREDGFFSLEKDQEALVAYLEEVKDKTIFFDTEIERLRYLVDN
DFYFNVFDIYSEADLIEITDYAKSIPFNFASYMSASKFFKDYALKTNDKSQYLEDYNQHV
AIVALYLANGNKAQAKQFISAMVEQRYQPATPTFLNAGRARRGELVSCFLLEVDDSLNSI
NFIDSTAKQLSKIGGGVAINLSKLRARGEAIKGIKGVAKGVLPIAKSLEGGFSYADQLGQ
RPGAGAVYLNIFHYDVEEFLDTKKVNADEDLRLSTISTGLIVPSKFFDLAKEGKDFYMFA
PHTVKEEYGVTLDDIDLEKYYDDMVANPNVEKKKKNAREMLNLIAQTQLQSGYPYLMFKD
NANRVHPNSNIGQIKMSNLCTEIFQLQETSIINDYGIEDEIKRDISCNLGSLNIVNVMES
GKFRDSVHSGMDALTVVSDVANIQNAPGVRKANSELHSVGLGVMNLHGYLAKNKIGYESE
EAKDFANIFFMMMNFYSIERSMEIAKERGIKYQDFEKSDYANGKYFEFYTTQEFEPQFEK
VRELFDGMAIPTSEDWKKLQQDVEQYGLYHAYRLAIAPTQSISYVQNATSSVMPIVDQIE
RRTYGNAETFYPMPFLSPQTMWYYKSAFNTDQMKLIDLIATIQTHIDQGISTILYVNSEI
STRELARLYVYAHYKGLKSLYYTRNKLLSVEECTSCSI
NT seq 2097 nt   +upstreamnt  +downstreamnt
atggaagagaaaaagtacaatcatattgaattaaataatgaggtcactaaacgaagagaa
gatggattctttagtttagaaaaagaccaagaagctttagtagcttatttagaagaagta
aaagacaaaacaatcttcttcgacactgaaatcgagcgtttacgttatttagtagacaac
gatttttatttcaatgtgtttgatatttatagtgaagcggatctaattgaaatcactgat
tatgcaaaatcaatcccgtttaattttgcaagttatatgtcagctagtaaatttttcaaa
gattacgctttgaaaacaaatgataaaagtcaatacttagaagactataatcaacacgtt
gccattgttgctttatacctagcaaatggtaataaagcacaagctaaacaatttatttct
gctatggttgaacaaagatatcaaccagcgacaccaacatttttaaacgcaggccgtgcg
cgtcgtggtgagctagtgtcatgtttcttattagaagtggatgacagcttaaattcaatt
aactttattgattcaactgcaaaacaattaagtaaaattgggggcggcgttgcaattaac
ttatctaaattgcgtgcacgtggtgaagcaattaaaggaattaaaggcgtagcgaaaggc
gttttacctattgctaagtcacttgaaggtggctttagctatgcagatcaacttggtcaa
cgccctggtgctggtgctgtgtacttaaatatcttccattatgatgtagaagaattttta
gatactaaaaaagtaaatgcggatgaagatttacgtttatctacaatatcaactggttta
attgttccatctaaattcttcgatttagctaaagaaggtaaggacttttatatgtttgca
cctcatacagttaaagaagaatatggtgtgacattagacgatatcgatttagaaaaatat
tatgatgacatggttgcaaacccaaatgttgagaaaaagaaaaagaatgcgcgtgaaatg
ttgaatttaattgcgcaaacacaattacaatcaggttatccatatttaatgtttaaagat
aatgctaacagagtgcatccgaattcaaacattggacaaattaaaatgagtaacttatgt
acggaaattttccaactacaagaaacttcaattattaatgactatggtattgaagacgaa
attaaacgtgatatttcttgtaacttgggctcattaaatattgttaatgtaatggaaagc
ggaaaattcagagattcagttcactctggtatggacgcattaactgttgtgagtgatgta
gcaaatattcaaaatgcaccaggagttagaaaagctaacagtgaattacattcagttggt
cttggtgtgatgaatttacacggttacctagcaaaaaataaaattggttatgagtcagaa
gaagcaaaagattttgcaaatatcttctttatgatgatgaatttctactcaatcgaacgt
tcaatggaaatcgctaaagagcgtggtatcaaatatcaagactttgaaaagtctgattat
gctaatggcaaatatttcgagttctatacaactcaagaatttgaacctcaattcgaaaaa
gtacgtgaattattcgatggtatggctattcctacttctgaggattggaagaaactacaa
caagatgttgaacaatatggtttatatcatgcatatagattagcaattgctccaacacaa
agtatttcttatgttcaaaatgcaacaagttctgtaatgccaatcgttgaccaaattgaa
cgtcgtacttatggtaatgcggaaacattttaccctatgccattcttatcaccacaaaca
atgtggtactacaaatcagcattcaatactgatcagatgaaattaatcgatttaattgcg
acaattcaaacgcatattgaccaaggtatctcaacgatcctttatgttaattctgaaatt
tctacacgtgagttagcaagattatatgtatatgcgcactataaaggattaaaatcactt
tactatactagaaataaattattaagtgtagaagaatgtacaagttgttctatctaa

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