Tachyglossus aculeatus (Australian echidna): 119950343
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Entry
119950343 CDS
T10703
Symbol
INSR
Name
(RefSeq) insulin receptor isoform X1
KO
K04527
insulin receptor [EC:
2.7.10.1
]
Organism
tacu Tachyglossus aculeatus (Australian echidna)
Pathway
tacu04010
MAPK signaling pathway
tacu04014
Ras signaling pathway
tacu04015
Rap1 signaling pathway
tacu04022
cGMP-PKG signaling pathway
tacu04066
HIF-1 signaling pathway
tacu04068
FoxO signaling pathway
tacu04072
Phospholipase D signaling pathway
tacu04081
Hormone signaling
tacu04150
mTOR signaling pathway
tacu04151
PI3K-Akt signaling pathway
tacu04152
AMPK signaling pathway
tacu04211
Longevity regulating pathway
tacu04213
Longevity regulating pathway - multiple species
tacu04520
Adherens junction
tacu04910
Insulin signaling pathway
tacu04913
Ovarian steroidogenesis
tacu04923
Regulation of lipolysis in adipocytes
tacu04930
Type II diabetes mellitus
tacu04931
Insulin resistance
tacu04932
Non-alcoholic fatty liver disease
tacu04960
Aldosterone-regulated sodium reabsorption
tacu05010
Alzheimer disease
tacu05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
tacu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
119950343 (INSR)
04014 Ras signaling pathway
119950343 (INSR)
04015 Rap1 signaling pathway
119950343 (INSR)
04066 HIF-1 signaling pathway
119950343 (INSR)
04068 FoxO signaling pathway
119950343 (INSR)
04072 Phospholipase D signaling pathway
119950343 (INSR)
04022 cGMP-PKG signaling pathway
119950343 (INSR)
04151 PI3K-Akt signaling pathway
119950343 (INSR)
04152 AMPK signaling pathway
119950343 (INSR)
04150 mTOR signaling pathway
119950343 (INSR)
09133 Signaling molecules and interaction
04081 Hormone signaling
119950343 (INSR)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04520 Adherens junction
119950343 (INSR)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
119950343 (INSR)
04923 Regulation of lipolysis in adipocytes
119950343 (INSR)
04913 Ovarian steroidogenesis
119950343 (INSR)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
119950343 (INSR)
09149 Aging
04211 Longevity regulating pathway
119950343 (INSR)
04213 Longevity regulating pathway - multiple species
119950343 (INSR)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
119950343 (INSR)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
119950343 (INSR)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
119950343 (INSR)
04932 Non-alcoholic fatty liver disease
119950343 (INSR)
04931 Insulin resistance
119950343 (INSR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tacu01001
]
119950343 (INSR)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
tacu04090
]
119950343 (INSR)
Enzymes [BR:
tacu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
119950343 (INSR)
Protein kinases [BR:
tacu01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
119950343 (INSR)
CD molecules [BR:
tacu04090
]
Proteins
119950343 (INSR)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
Insulin_TMD
fn3
Kinase-like
Toxin_29
B2
Motif
Other DBs
NCBI-GeneID:
119950343
NCBI-ProteinID:
XP_038628579
LinkDB
All DBs
Position
X1:119451855..119635748
Genome browser
AA seq
1384 aa
AA seq
DB search
MGPKATALVMALALVLGGSGSPGRSLYEGPVCPNMDIRNNLTQLYALENCSVIEGHLQIL
LMFKTKPEDFRGLSFPKLTMITDYLLLFRVYGLESLKDLFPNLTVIRGTRLFFNYALVIF
EMVHLKEIGLYNLMNITRGAVRIEKNNELCYLSTIDWSRILDSVEDNYIVENKDDKEECG
DVCPGTVKGKSSCPATVINGLFIERCWTHDHCQKVCPAPCKWQGCTSDGQCCHSECLGNC
SEPNDPEKCIACRHFDLDGKCVETCPPNYYRFQEWRCVNFSFCQNLHNNCKNSRQSGCHQ
YVIHNNKCVPECPSGYIMNSTNLNCSPCSGPCPKVCNMYGEKTIDSVTSAQELQGCTVIN
GSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLHLIKGETLEAGN
YSFYALDNQNLRQLWDWSKHNLTIAQGKLFFHYNPKLCLSEIHKMEEISGTKGRQERNDI
ALKTNGDQASCENELLRFSQIRTSFDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQNVTE
FDGQDACGSNSWTVVDVEPPQRSNDPKSQSSPGWLMRGLKPWTQYAVFVKTLVTFSDERR
TYGAKSEIIYVQTNATVPSVPLDPISVSNSSSQIILKWKPPSEPNGNITHYLVFWEQQAE
DSELYELDYCLKGLKLPSRTWSPPFESEDSQKQNRSDNEDHGGECCSCPKTDSQIQKEAE
ESSFRKTFENYLHNEVFVPRKTSSGNGSVDIRPNRKRRDLGSRANATVVTPTIPPLSNTS
STPAPESREEQKPFEKVESKESLVISGLRHFTGYRIELHACNHDAQESRCSVAAYVSART
MPEAKADDIVGPVTHEVSDNNIVHLKWQEPKEPNGLIVLYEVNYWRLGENEENMLPFSFL
QELHYCVSRKHFANEHGCKLRGLHPGNYTVRIRATSLAGNGSWTEPTYFYVADYLDVPSN
IAKIIIGPVIFAIFVVGMIGAIYLFVKKRQTEGPTGPLYASSNPEYLSASDVYVPDEWEV
PRDKISLLRELGQGSFGMVYEGNAKDIIKGELETHVAVKTVNESASLRERIEFLNEASVM
KGFSCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPDAENNPGRPPPTLPEMIQ
MAAEIADGMAYLNAKKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLL
PVRWMAPESLKDGVFTAYSDVWSFGVVLWEISSLAEQPYQGLSNEQVLKFVMDGGYLDQP
DNCPERVNHLMQMCWQYNPKMRPTFIEIIEMLKEDLHPSFQSVSFFYSEENKPPEAEEFE
MDFENMESIPLDPSSYSQRDEVLGRDNGPSLALKGNYEEHIPYTHMNGGKKNGRILSLPR
SSPS
NT seq
4155 nt
NT seq
+upstream
nt +downstream
nt
atgggacccaaggcgacggcgctggtgatggccctggcgttggtgctgggcggttcgggc
agcccgggacggagcctatacgaggggccggtttgcccgaacatggacattcgaaataac
ctgacacagctgtatgctctagaaaactgctctgtgattgagggccacttgcaaatactg
ctcatgtttaaaaccaagcctgaagatttccgaggacttagttttcccaaacttactatg
attacagactatttattacttttccgggtgtatggcctagagagtttaaaggacctcttc
cccaatctcactgttatccgtggaacccgtctcttttttaactatgccctggtcatcttt
gagatggtccacttgaaagaaattggcctttacaatctaatgaatatcacccgaggagca
gttcggattgagaagaataatgagctatgctacttgtccactattgactggtctcgaatt
ttagattctgttgaagataactacattgttgaaaacaaagatgataaagaagaatgcgga
gatgtttgtccaggaactgtgaaaggaaaaagcagctgcccagctactgtaataaatggt
cttttcatcgaaaggtgttggacccatgaccactgtcagaaagtttgtccagccccctgt
aagtggcagggttgcacctcagatggtcagtgctgtcacagcgagtgcctgggaaactgc
tcagagccgaatgatcccgagaaatgcattgcctgccggcacttcgacctcgatggcaag
tgtgttgaaacttgcccgccgaattactatcgctttcaggagtggcgttgtgtgaatttc
agcttctgccagaatctgcacaacaattgcaagaattccaggcaatctgggtgccaccaa
tatgtcattcacaacaacaagtgtgttcctgagtgtccctctggatatattatgaattcc
accaacctgaattgctctccttgttcagggccctgtccaaaggtttgtaatatgtatggt
gagaagaccattgattcagtaacatctgcacaggagcttcaagggtgtactgtcataaat
ggaagcttgatcataaacatacgtggaggcaataatttagcggcagaactggaagccaac
cttggcttaattgaagaaatttcgggttacctgaaaatccgtcgttcctatgccttagtg
tctctgtctttcttccgtaaactgcatctgattaaaggggagacccttgaagctgggaat
tattctttctatgccctggataatcagaacctgagacagctatgggactggagtaaacac
aatctcaccattgcccaaggaaaattgttcttccattataaccccaaactctgcttatca
gagattcacaaaatggaagaaatctccggaaccaaggggcgtcaagaaagaaatgacata
gccttgaagacgaatggtgaccaagcatcctgtgaaaatgagctactcagattttcccaa
atcagaacatctttcgacaagatcttactaaaatgggaaccttactggccacctgatttt
cgagacctcttgggatttatgcttttctacaaagaagccccatatcaaaatgtgactgaa
tttgatggtcaagatgcttgtggttcaaacagttggacagtggttgatgtagagcctccc
cagcggtcaaatgatcccaaatcccagagctctccaggatggctaatgagggggttgaaa
ccttggacccagtatgctgtctttgtcaaaaccttagtcaccttttctgatgagcgaaga
acatacggagcaaagagtgaaatcatctatgtccagaccaatgctacagttccttctgtt
cccttagatccaatatcagtttccaattcctcatcccagatcattttaaagtggaaacca
ccttcagagccaaatggcaatatcacacactacttagtgttctgggagcaacaggctgag
gatagcgaactctatgaacttgattattgcctgaagggattaaagctgccttcaaggacc
tggtctcctccttttgaatctgaagattctcagaaacagaatcgaagcgataatgaggat
catggtggagagtgttgttcttgtccaaaaactgattcccaaatacagaaagaagctgaa
gagtcttcatttaggaaaacatttgaaaattatctccataatgaggtttttgtgcccaga
aaaacatcatcagggaatggatctgtggacattaggccaaatcgtaaacgaagggatctt
ggcagcagggcaaatgccacagtggtgacacccacaattccacctttgtcaaacacctca
tctacacctgcccctgaaagtagagaggaacagaaaccctttgagaaagttgaatctaag
gaatccttggttatctccggtctgcggcattttactggctatcgcattgaactccacgcc
tgcaatcatgatgcccaagaatccagatgcagcgtggctgcgtatgtcagtgcaagaacc
atgcctgaagcaaaggcagatgacattgttgggccggttactcatgaagtgtctgacaat
aacattgtccacttgaagtggcaggagccaaaggagcccaatggattgattgttctctat
gaagtgaactattggcgtcttggagaaaatgaggaaaacatgcttcctttttcctttttg
caggaactgcattattgtgtttcccggaaacattttgccaacgaacatggatgtaaactc
cgtggcctgcatcccgggaattacactgttcgaattcgagccacttcattggcaggaaat
ggctcttggaccgaacccacctatttctatgttgcggattatttagatgttccgtcgaat
attgcaaaaattatcattggcccagtcatttttgccatttttgttgttggaatgattggc
gctatttacctgtttgtgaaaaagaggcaaacggaaggaccaaccgggccactttatgcc
tcgtccaatccagaatacctcagtgctagtgatgtttatgtcccagatgagtgggaggta
ccacgagacaaaatcagcctcctacgggaattgggccagggctcctttgggatggtgtat
gaaggaaacgcaaaggatatcataaaaggagagctagagacgcacgtagcggtgaaaacc
gttaatgaatctgcaagtcttcgggaacgcattgagtttttaaatgaagcctctgtcatg
aaaggttttagctgccatcatgtggtccgcctcttaggagtggtctccaaaggacagccc
acattggtagtgatggagctgatggcccatggagatctaaaaagttacctccgttctttg
cgcccagatgctgaaaataaccctggccgccccccgccaacactcccggagatgattcag
atggccgccgagatcgcagatggcatggcctacttgaatgcaaagaaatttgttcaccga
gatctagcagcccgaaattgtatggttgcggaagactttaccgtaaagattggagatttt
ggaatgaccagagacatctacgaaactgattattaccgaaaaggagggaagggtctgctc
cctgtaagatggatggcccctgagtccttaaaggatggagtctttacagcatattctgat
gtgtggtcttttggcgtggtcctttgggagatcagcagcttggccgaacagccttaccag
ggtctgtctaatgagcaggtgctgaaatttgtaatggatggagggtacctggatcaacct
gataactgtcctgaaagagtaaaccacctgatgcagatgtgctggcagtataaccccaaa
atgcgccccaccttcatcgagatcattgagatgctgaaagaggacctgcatcccagcttt
cagagcgtgtcatttttttacagcgaggaaaacaagcctccagaagctgaggaattcgag
atggactttgaaaacatggagagcattccgctcgacccatcttcatactcccagagggac
gaagtcctggggcgggacaatgggccatctctggctctaaagggaaactacgaagaacac
ataccttacacccatatgaatggtggcaagaaaaacggacgcattctgtccctccctagg
tcgagcccttcctaa
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