Thermobifida alba: FOF52_14090
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Entry
FOF52_14090 CDS
T08159
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
talx
Thermobifida alba
Pathway
talx00860
Porphyrin metabolism
talx01100
Metabolic pathways
talx01110
Biosynthesis of secondary metabolites
talx01120
Microbial metabolism in diverse environments
talx01240
Biosynthesis of cofactors
Module
talx_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
talx_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
talx_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
talx00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
FOF52_14090
Enzymes [BR:
talx01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
FOF52_14090
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
FOF52_14090
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Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
UPT21949
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Position
complement(3201649..3203334)
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AA seq
561 aa
AA seq
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MNPQTETPATGAEEAAKPAAGHIALVGAGPGDADLLTLRGAALLGQADVVLTFREFGPLA
RHREGLLRHCRPDVEVVGPDEYGDKGDAFAVAKAAQGLRVVRLYAGDPLLACRGADLAEA
ARDAGIEFEIAPGLPAITAVPAYAGTELMPAGTNELRVLDAADTDVDWVNAAQSKATLVV
MFPDAPSEDDPEAKGPGLDRICKTLIAGGRPDTTPVTVTRMGTTTQQTTVTSTLARLAAD
LKASDAKGHTVPRPSLMIIGEGAQRQRKLSWFETKPLFGWRVLVPRTREQAAALSDQLRG
YGAVPEEVPTISVEPPRTPQQMERAVRGLVTGRYQWVAFTSVNAVKAIRERLEDYGLDAR
AFAGVKVAAVGEQTAAALQAFGIHPDLQPPEDKQSGAGLVEVWPPYDAEIDPIERVLLPR
ADIATEVLSEGLVKLGWEIDDVTAYRTVRAAPPPAPIREAIKGGGFDAVLFTSSSTVRNL
VGIAGKPHATTVIAVIGPETAKTAEEFGLRVDVRAPKASVVALAEALAEFGAAQRQAAIE
AGKPVLRPSQKRRGRRRKTML
NT seq
1686 nt
NT seq
+upstream
nt +downstream
nt
gtgaacccgcagactgagaccccggcgaccggggccgaggaagccgccaagcccgcagcc
ggccacatcgcgctggtcggtgccgggccgggcgacgccgacctgctgacgctgcggggc
gccgcgctgctggggcaggccgacgtcgtcctcacgttccgcgagttcggaccgctcgcc
cggcaccgggaggggctgctgcgccactgccgtccggacgtggaggtcgtcggccccgac
gagtacggggacaagggagacgcgttcgcggtcgccaaggcggcccagggactgcgcgtg
gtccggctctacgccggtgacccgctgctggcctgccggggcgccgacctggccgaggcc
gcccgcgacgcgggcatcgagttcgagatcgcaccggggctccccgcgatcaccgcggtt
cccgcctacgcggggaccgagctgatgcccgccggcaccaacgagctccgggtgctcgac
gccgccgacaccgacgtggactgggtcaacgccgcgcagagcaaggccaccctggtcgtg
atgttccccgacgcgcccagcgaggacgacccggaggcgaagggacccggcctcgaccgg
atctgcaagaccctcatcgcgggcggccgtcccgacaccaccccggtcacggtgacccgg
atggggacgaccacccagcagaccaccgtcacctccaccctggcccgcctggccgccgac
ctgaaggcctccgacgccaagggccacacggttccccgcccgtccctgatgatcatcggg
gagggggcgcaacgccagcggaagctctcctggttcgagaccaagccgctgttcggctgg
cgggtcctggtaccgcgcacccgcgagcaggccgcggccctctccgaccagctgcgcggc
tacggggcggtgcccgaggaggtccccaccatctcggtggagccgccgcgcaccccgcag
cagatggagcgggcggtccgcggcctggtcaccggccgctaccagtgggtggccttcacc
tccgtcaacgcggtcaaggccatccgcgagcgtctggaggactacggtctggacgcgcgc
gccttcgccggggtgaaggtcgccgcggtgggggagcagaccgccgccgcgctgcaggcg
ttcggcatccaccccgacctgcagccgcccgaggacaagcagtccggagcgggcctggtc
gaggtgtggccgccctacgacgccgagatcgacccgatcgagcgggtgctgctgccgcgc
gccgacatcgccaccgaggtcctctccgagggcctggtcaaactcggctgggagatcgac
gacgtcaccgcctaccgcaccgtgcgcgccgcgcccccgcccgcgcccatccgcgaggcc
atcaagggcggcgggttcgacgcggtgctgttcacctcctcctccacggtccgcaacctc
gtcggcatcgcgggcaaaccgcacgccaccacggtgatcgccgtgatcgggccggagacc
gccaagaccgccgaggagttcgggctgcgcgtggacgtgcgcgcgccgaaggcgtcggtg
gtggcgctggccgaggcgctcgcggagttcggcgcggcccagcggcaggccgcgatcgag
gcgggcaagccggtgctgcgccccagccagaagcgccggggccgccgccgcaagaccatg
ctgtga
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