Trematomus bernacchii (emerald rockcod): 117486922 Help Entry 117486922         CDS       T09643                                  Symbol ryr3 Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism tben  Trematomus bernacchii (emerald rockcod) Pathway tben04020   Calcium signaling pathway tben04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:tben00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     117486922 (ryr3)    04020 Calcium signaling pathway     117486922 (ryr3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:tben04040]     117486922 (ryr3) Ion channels [BR:tben04040]  Voltage-gated cation channels   Ryanodine receptor    117486922 (ryr3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans Motif Other DBs NCBI-GeneID:  117486922 NCBI-ProteinID:  XP_033991406 LinkDB All DBs Position Unknown AA seq 4851 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQCVATIQKEHRKFCLAAEGLGNRVCYLESTSEAKYVPP DLCVCNFVLEQSLSVRALQEMLAKTGSNSEGAGQGGGHRTLLYGHAILLRHSFSDMYLTC LKTSRSLTDKLSFDVGLQEDSIGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSTERYL HLSNANGHAQVDASFMQTLWNVQPTCSSGNVAVGYLTGGHVMRLCHGHDESLSIPGANKS EEEQRIVNYEAGKGASRARSLWRLEPLRISWSGSHIRFGQAFRLRHLATGHYLAMTEDPG LVLQDRERSDTTATSFCFRPSKEKGEVGPKRDIDGMGVPEIKYGDSMCFVMHVATGLWLS YLAPDAKSSRLGPLKRRACLHSEGHMDDGLILQRCQHEESRAARIIRNSTFLFANFIKAL DSIAEGESKAVAGYVEEVLQTLNDLIEYFKQPDSELEHEEKQCLLRSLIKRQDLFKDEGM LSLLSKCIDRMNLYNSAAHFAEVAGEKAGTAWKDILNLLYELLAALIRGNRNNCTQFSRN LDWLVSKLERLESSSGILEVLHCILVESPEALNIIQRGHIQSIISLLYKNGRNYKILDVL CSLCVCNGVAVRANQNLICDNLLPKRDLLLQTRLVNDVQSMRPNIFLGVAEGSAQYKKWY FELVIDQVDHFVTGEPTHLRVGWANTKGYAPYPGGGEGWGGNGAGDDLYSYSFDGLHLWS GRIPRAVASINQHLLNSDDVVSCCLDLGAPSMSFRINGQPVQGMFEDFNTDGFFFPVVSF SAGVKVRFLLGGRHGDFKFLPPAGYSPCYEALLPKEKMHVEPVKDYKRDHDGVRDLLGTT KFLSQASFIPTPVDTSQIVLPPHLDNVRDKLAENIHELWGMNKIELGWTYGKVRDDNKRQ HPCLVDFGKLPETERNYNVQMSSETLKTLLALGCHVAQAFANAEDDLKKVKLPKDYMMSN GYKPAPQDLSDVKLNAGQEVLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKSRRNPRLVP YALLDERTKKSNRDSLREAIRTMVGYGYDIDPPDQEALHTLDDQNIETIRFFRVEQTYAL KTGKWYFEFEALSGGDMRVGWARPGCRPDVELGTDNQAFVFDGYRGRRMHAGSRYFGQPW KMGDVVGCMINMEDKSMIFTLNGELLITSKGSELCFTDFETEDGFIPVCSMGIGQVGHMN LGKDASTFKYYTMCGLQEGFEPFGVNMNRAITMWFSKRLPTFVNIPKEHQHIKVTRIDGT VDNPPCLKVTHKTFGTQNSNSDMTYCRLSMPVDFYSADKILDESLKLSHLPKEDGTVDFG NNTTYYHSVRVFAGQDPASIWVGWVTPDYHFYSKDFSLNKMRRVTVTLGDERGRVHESVQ RSNCYIVCGADAIDPSSSSRSNSDLEIGCQIDLATGLVSFTANGKELSTSYQVEPNTKLF PAVFVRPTSANLFQFEFVKIKDAMPLSSAIFKSESRNPVPQCPPRMDVQTIVSVLWSRMP NTFLRVEVARVSERHGWVVQCLEPLEMLAVHIPEENRCLDILELSELEGLRKFHYHTLKL YSALCALGNTRVAHALCSHLDQSQLLYTIDNQYLSGMLREGFYNVLISIHLETAKEARLM MNNEFIIPVTAETRSIKLFPDESKRHSLPGVDLSTSLKPRVNFSPVGIINTRRQQYLYSP EIPLGSLKEKAISMLTEAVQGGGTHIRDPVGGSVEYQFVPILKLTGTLLTMGVLTSEEVR IILLLIAPNVFGEAKEGEDAKGDQVAVAGEKEEVSKNEEKAVEAGEDETKDSKPLIKGLL AKSLPEPVKRQMCELLHYFCDCELKHRIESIVSFSDDFVSKLQYNQKFRYNELMLAFEMS AAVTAKKTKEFRSPPHEQINILLNFSAGEDCPCPEEIQEELNIFHEELRLHCGIPIEEEE EEQDTSIKGRLLALLYKIKGPPQKPEAEPTEQEQAAPTNLKELISQTITSWAQESHIQDP ELVRVMFSLLRRQYDGIGELLRTMRKSYTISAASVQDAINLLVSLGQIRSLLSVRMGKEE EKLMIDGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGGDKLQEIAFPKMVASCCR FLCYFCRISRQNQKAMFDHLGYLLENSSVGLASEAMRGSTPLDVAASSVMDNNGLALALE EPDLEKVVTYLAACGLQSCAMLLAKGYPDLGWNPIEGERFLSFLRFVVFCNGESVEENAN VVVKLLIRRPECFGPALRGEGGQGLLAAMQEAIKISDNPALDLPESAAGVNNGSGEEEGE VIHMGNAIMSFYSALIDLLGRCAPEMHLINAGKGEALRIRAILQSLVPTTDLVGIISIPL NMPVLNKDGTVMTEPDMSACFCPDHKAPMVLFLERVYGIEDQSFLLQMLEVGFLPDLQAS ASLDTELLSTTETALAMNRYIGSALLPLLTRCAALFSSTEHYAQLIDSTLQTIYRLSKGR SLTKAQRDAIEECLLAICMHLRPSMMQQLLRRLVFDVPMLSEYCQIPLRLLTNHYEQNWK YYCLPSGMINCGVSSEEELLLTKKLFWGIFDSLSQKKYDADLFKIATLCLCAIAGALPPD FVDTSFGATLEKQAPVDAKGNFDPKPINTANISLPEKLESIANKYAEHSHDKWSSDKVSA GWKQGDSLDDQAKTHPLLKPYKALSEKERETYRWPVKESLKSMLAMGWNIERSKEGESVI QQRESEKRKTPDSQNDGFSPAPMDLNNVTLSRELQGMVEVVAENYHNIWSKKKKSELVSK GGGSHPLLVPYDTLTAKEKYRDREKAQELFKFLQISGYAIMRDQKDVGQDSSSMEKRFTY KLLKTLLKYVDSAQEFIAHLEAMATSGKTDKSPHDQEIKFFAKVLLPLIDQTFKNHCLYF LSTASNNLSSCGCASNKEKEMLTSLFCKLALLVRHRISLFGSDSAMMVSCLHILSQTVDT RTVMKSGSELVKASFKTFFENAAEDLEKLVEMLKLGKFMQSRAQLKSVTQSINYVTVALL PILTALFEHITTYEFGVDLLLNDVQLSCYRILASFYCLGTGKSVFVEKHLPALGESLATL VAAMPVAFLEPQLNAHNPMSVFNTKTPRERAILSMPDTVMEMCPEMPRLEGLLKDVSDVS ESGARYSDMPQVIEVILPMLCNYLSYWWEKGPENSSSDAQCCTMVTSEHLSIILANILKI LNNNLGIDDAPWMKRIAVYSQPIICKAGAHLLRTHFLPTLEKLRNKTVKVVGEEELLKAD SKGDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRSRWLKEPDADSTELFRMVAEIF ILWCKSHNFKREEQNFVVQNEINNLGFLTGEGKAKMSKSGGDQERKHKRRRGEYYSVQTS LIVAALKKLLPIGLNMCTPGDQELISLAKIRYSLKETDDEVKEHLRLNFHLQDKCEDPAV QWQMNLYKDVVVKSEEPANLEHTVDRVQSISAAVFHLEQVEQPLRNKKLVYHKLLSKQRK RAVVACFRMAPLYNLPRHRAINFFIPAYQRLWIEAEEYSFEEKLVQDLAKTPMKIVEEEE EEVAEVQPDPLHQLILHFSHNALTERSYLEEDPLYIAYADMMAKSCAEDDEEEEEEEVEG KEKTFEEKEMEKQKILYQQMRLHARGAAEMVLQMISASKGRLGPMVTCTLKLGISILNGG NVQVQQKMLDYLKEKRDAGFFKGLSGLMQSCSVLDLNAFERQNKAEGLGMVSEEGSINNQ QGSKVLQNDEFTKDLFRFLQLLCEGHNGDFQNFLRTQTGNTTTVNIIISTVDYLLRLQES ISDFYWYYSGKDVMDETGRLNFSKALSVAKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAV VGFLHVFANMQMKLSQDASQIELLKELMDLQKDMVVMLLSLLEGNVVNGMIGKQMVDTLV ESSSNVEMILKFFDMFLKLKDLTSSDTFKENDPEFKGIISKKEFQKSMESQMQYSQTEIE FLLSCAEADENDMFNYIDFVERFHEPAKDIGFNVAVLLTNLSEHMPHDSRLATFLDLAGS VLSYFEPYLGRIEIMGSAKRIERVYFEISESSREQWEKPQVKESKRQFIFDVVNEGTESE KMEMFVNFCEDTIFEMQLASQISEPDVVEQPEEEEEDDAHSLLDELGGEEEGALESASAF TTACRSVKRKISNVRQTLSVKNFSKQFKKIKKLSIKEIITSFFSFFWMLFTGFFKGIYGL IFGFFHVIWSSMFGGGLVEGAKNIKVTDILGNMPDPTQFGIHGDAIEGEKVEAIESSGGL ETAMAPAGDTTEMDSMLEMLSAPKKEGGKHVELGLGDFSELSAEISTSEHKKKAAAKPVE APENEPEKADSENQEKEDKPKKEEVEVKEPVAEEKPKAKASPPKDASPSFMLSIFAFLKI FITKMLNLLARNFYNVRFLALFVCFAINFILLFYKVTGEAEVDEEDTWDGDEDNDEENTF FDMDEFVLQESSGYMLPTLRFLAVFHTVISLVCLFGYCFLKVPLVVFKREKEIARKLEFD GLYITEQPSDEDIKGQWDRLVINTPSFPSNYWDKFIKRKVINKYGDMYGAERIAELLGLD KSALDFDPTVETVENEASLLSWLSSIDTKYHIWKMGVVLTDNYFLYLIWYSTMSIFGHFN NFFFAAHLLDIAMVFKSLQTILSSVTHNGKQLMLTVGLLAVVVYLYTVVAFNFFRKFYNG GDEDEPDMKCDDMLTCYLFHMYVGVRAGGGIGDELEDPAGDPYELYRIMFDITFFFFVIV ILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDRTPHGFETHTLQEHNLA NYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPTGDCFRKQYEDQLG NT seq 14556 nt NT seq  +upstreamnt  +downstreamnt atggctgaaggcggagaaggtgaagacgaaatccagttcttgagaactgatgatgaggtg gtgctccagtgtgtggccaccatccagaaggagcatcgcaagttttgcctggctgccgag ggactgggaaaccgtgtgtgttatctggaatccacttcagaagctaagtatgttcctcca gacctgtgtgtgtgtaactttgtgttggagcagtccctgtcggtgcgggctctgcaggag atgctggctaagactgggtcgaacagtgaaggggcgggtcaggggggtggacaccggacc ttgctctacggtcatgccatcctacttcgccactccttcagtgatatgtacctgacctgt ttgaaaacatcgaggtctctgacagacaagctgtcatttgatgtcggcttacaagaagat tcgataggagaggcctgctggtggaccatccaccctgcgtccaagcagagatccgaggga gagaaggtccgcatcggagacgacctgatcctagtcagcgtgtccacagagagatacctg cacctctctaacgccaatggacacgcccaggtggacgcgtccttcatgcagaccctgtgg aacgtccagcccacctgctcttcaggcaacgtggctgtaggttatttgactggtggacat gtgatgcgtctttgtcatgggcatgatgagagcctgtccatccctggagcaaacaagagt gaggaggagcagaggatagtcaactatgaagcggggaagggagcgtcaagagctcgctct ctttggagactggagcctctcaggatcagctggagcggcagccacatccgcttcggtcag gccttcaggctccgccacctcgcgaccggtcattacctggccatgacggaggaccccgga ctggtcctgcaggacagggagaggtccgacaccacggccacttccttctgcttcaggccc tccaaggaaaaaggcgaggtgggcccaaagagagacatcgatggcatgggggtgccggag atcaagtacggagactctatgtgcttcgtcatgcacgtagcgacgggactgtggctgtcc tacctggcgcctgatgccaaatcatctcgtctgggacccctgaaaagaagggcctgcctg cactctgagggccacatggacgacgggctcattctgcagcgctgtcagcatgaggagtct cgcgctgctcgcatcatccgcaacagcacattcctcttcgccaactttatcaaggctttg gacagcattgcggagggcgagtccaaggcggttgcgggatatgttgaagaggtgctgcag acgctcaacgacctgatcgagtatttcaaacagcccgattcagagctggagcacgaggag aagcagtgtctcctccgttcactcatcaaacgccaagacctcttcaaagatgagggcatg ctgtccctcctgtctaaatgcattgaccggatgaacctgtacaacagcgctgcccacttt gcagaggtggctggggagaaggccggcacagcgtggaaggacatcctcaacctcctctat gaactcctggccgcactgatccgtgggaacaggaacaactgcacccaattttcccgcaac ttggactggttggtcagcaaactggagagactggaatcttcatcagggatcctggaagtc ctccactgtatcctggtggaaagtccggaggctctgaacatcattcagagaggtcacatt caatccataatctctctgctttacaagaatggacgcaactacaagattctggatgtcctc tgttccctctgtgtttgtaacggggttgcagtgagagccaatcagaatctgatctgtgac aacctgcttcccaagagagacctgctgcttcaaactcgactcgtcaatgatgttcagagt atgaggccgaacatcttcctgggtgtggctgaaggttcagctcagtataagaagtggtat tttgagctggtgatcgaccaggtggaccactttgtaaccggagagccgacccacctgaga gtgggctgggccaacactaaaggctacgctccgtaccccgggggaggagaggggtggggc ggcaacggtgctggagacgacctgtactcctacagctttgatggacttcatctctggtca ggccgaatccccagggccgtggcctccattaaccagcacctgctgaactcagacgacgtg gtgagctgctgtctggatctgggcgctcccagcatgtccttcaggatcaacgggcagcct gtccagggcatgttcgaagacttcaacaccgacggcttcttcttccccgtcgtcagcttc tctgcaggtgtcaaggtccgtttcctgttgggtggacgtcacggagatttcaagttcctg ccgcccgctggttactccccctgctacgaggcgctgctgcccaaagagaagatgcatgtg gagcctgtgaaggactacaagagggaccatgacggggtccgtgacctgctggggaccacc aagttcctctctcaggcctccttcatccccactcctgttgacaccagccagattgttctt ccccctcacctggacaacgtccgggacaagctggcagaaaacatccacgagctgtggggg atgaacaagatcgaactgggctggacctatggcaaggtccgtgatgacaacaagaggcag cacccatgccttgttgattttggaaagctgcctgaaactgaaaggaactacaacgtgcag atgtctagtgaaacacttaagaccctgttggctcttggctgccatgttgctcaggctttt gcgaatgctgaggacgatctgaagaaagtcaaacttcccaaagactacatgatgtctaat ggatataagcctgcgccacaggacctctctgacgtgaaactgaatgcaggtcaggaggtt ctggttgataaactggccgagaatgcacacaacgtgtgggccaaagacagaattaaacaa ggatggacctatggcatccagcaggatttaaagagcaggcgcaatcctcgcctggtgccg tacgctttactggacgagcgcacgaagaaatctaacagagacagcttgagagaggctatc aggactatggttggatatggatatgacatcgaccccccagaccaggaggctctccacacg ctggatgatcagaacatcgagaccatccgcttcttccgtgtggagcagacgtacgccttg aagacggggaagtggtactttgagtttgaggcgctgagtggaggagacatgagggtgggc tgggccagacccggctgcaggcccgatgtggagctggggacggacaaccaggccttcgtg ttcgatggatacaggggtcgtcgaatgcacgcaggaagccgctactttggacaaccttgg aaaatgggcgacgtggtcggttgcatgatcaacatggaggacaaatccatgattttcacc ctgaacggagagctcctgatcaccagcaagggctctgagctctgcttcaccgactttgag acggaggacggtttcatccctgtgtgcagtatgggcatcggacaggtgggacacatgaac ctgggaaaggacgccagtactttcaagtactacaccatgtgtggactccaggagggcttc gagccctttggtgtgaacatgaacagagccatcaccatgtggttcagcaagcgccttcct acctttgtcaacatacccaaagaacaccagcatatcaaggtgacgaggatcgacgggaca gtagacaaccctccctgcctcaaggtcacccacaagacgttcggcacgcagaacagcaac agtgacatgacctactgcagactgagcatgcctgtggacttctactctgcagacaagata ctggacgagtctctgaaactcagccatcttccaaaagaagatggaactgttgactttgga aacaacacaacttactaccactcagtgagagtgtttgccggacaggaccccgcctcaatt tgggtgggctgggtcacaccggactatcatttctatagcaaagacttcagcctcaacaag atgcggagagtcaccgtcaccctgggagacgagagagggcgggtacatgagagtgtgcag aggagtaactgctacatcgtgtgtggagcggacgccatcgacccgtcctcctccagccgc tccaactctgacctggagatcggctgtcagatcgacctggccactggcctcgtctccttc actgccaacggcaaggagctgtccacatcatatcaggtggagccaaatactaagctgttc ccagctgtgttcgtacgccccaccagtgcaaacctcttccagtttgaatttgtcaagatc aaggatgcaatgccgctctcgtctgccatatttaagagcgagagcaggaacccggtgccg cagtgcccgccgcgcatggatgtgcagaccatcgtgtccgtgctgtggagccgcatgccg aacaccttcctcagggtggaggtggctcgggtcagcgagaggcacggctgggtggtgcag tgtctggagccgctggagatgttggccgtacatattcctgaggagaacaggtgtttggac atcctggagttatctgagcttgaaggcctgagaaagttccactaccacactctgaagctg tacagtgccctctgtgcgctgggaaacacgcgcgttgctcacgccctctgcagccacttg gaccaatcacagctgctctacaccatcgacaaccagtacctgtctggcatgctgagggag ggcttctacaatgtcctcatcagcatccatcttgaaacggcaaaggaggctcgcctaatg atgaacaacgagttcatcatccctgtgaccgcggagactcgctccatcaaactgttccct gacgagtccaagcggcactcgctgcctggcgtggacctgagcacctctctcaaacctcga gttaacttctcgcccgtcggcatcatcaacacgaggcggcagcagtacctgtacagcccg gagatccctctgggcagcctgaaggaaaaggccatcagcatgctcaccgaggccgtgcag ggcggaggaacgcacatccgagacccggtgggcggcagcgtggagtaccagttcgtcccc atcctgaagctgacaggaacgctgttaaccatgggagtcctgaccagcgaggaggtgagg ataattctcctcctgatcgctcccaacgtgttcggagaggccaaggagggcgaggacgcc aagggggaccaggtggccgtggcgggggagaaagaggaagtgagcaagaacgaggagaag gctgtggaggcgggagaggacgagactaaagacagcaaaccgctcatcaaaggtctgctg gcaaagtccctgcccgagcccgtcaaacgccagatgtgcgagctgctgcactacttctgt gactgtgagctgaagcaccgcatcgagtccatcgtgtccttctcagacgacttcgtgtcc aagctgcagtacaaccagaagttccgctacaacgagctgatgctggcgtttgaaatgtcc gccgccgtcactgccaagaagaccaaagagtttcgttcacccccacatgagcagatcaat atcctgctgaatttcagtgcaggggaggactgcccctgtccggaggagatccaggaagaa ctcaacatcttccatgaagaattgcgactgcactgtggaattcccatagaggaggaagag gaagagcaggacacttcgataaaaggccgtctgctcgctttgctctacaagatcaaaggt ccgccccagaaacctgaggcagaacccactgagcaggaacaggccgctcccaccaacctg aaggagctgatctctcagaccataaccagctgggctcaggagtctcacatccaggatcca gagctggtccgagtgatgttcagcctgctcaggaggcagtacgacggcatcggggagctg ctccggaccatgaggaagtcctacaccatcagtgccgcctccgtgcaggatgctatcaac ctgttggtgtctctgggtcaaatcaggtctctgctgtcagtacgcatgggcaaagaagag gagaaactcatgattgatggacttggtgacatcatgaacaacaaagttttctaccaacat cccaacctgatgagagtgctgggcatgcacgagaccgtcatggaggtcatggtcaacgtg ctgggaggagacaagttgcaggagatcgcctttcccaagatggtggccagctgttgtcgc ttcttgtgctacttctgtcgtattagccggcagaaccagaaagccatgtttgaccacctg ggctacctgctggagaacagcagcgtggggctggcttctgaagccatgcggggctccact ccactggatgtagcagcttcttcagtgatggacaacaacggcctggctctggccctggag gagccggatctggagaaggtggtgacatacctggcagcctgtggtcttcagagttgtgcc atgcttcttgctaagggttacccagacctcggctggaaccctatagagggagagcgcttc ctgtccttcctgaggttcgtcgtcttctgcaatggtgagagtgtggaggagaatgctaac gtggtggtgaagctgctgatcagacgtcccgagtgtttcggccccgccctcaggggagag ggaggtcagggtttgctcgccgccatgcaggaggccatcaagatttccgataatcccgcc ctcgacctgcccgagagcgccgccggcgtcaataatggttctggtgaggaagaaggagaa gttattcacatgggcaacgccatcatgtccttctactcggctcttattgacctgctggga cgctgcgctccagagatgcatcttatcaatgcaggtaaaggtgaggcgctgcgtatccga gccatcctgcagtccctggttccaacgacagacctggtggggatcatcagcatcccgctc aacatgcctgtgcttaataaagatggcacggtaatgacagaacccgacatgtcggcctgt ttctgtccggaccacaaggcccccatggtgctcttcctggagagagtgtacggcatcgag gaccagagcttcctgctccagatgttggaggtcggcttcctgcctgacctccaagcctct gcgtctctggacacggagctgttgagcaccacggagacggcgttggccatgaaccggtac atcggctcggccctgctgcctctgctcacccgctgcgccgctctgttcagcagcacggag cactacgctcagctgatcgactccacgctgcagaccatctaccggctgtccaaaggacgc tcgctcaccaaagcccaaagggacgccatcgaggagtgtctgctggctatctgcatgcac ctacgtccctccatgatgcagcagctgctcagacggctggtgttcgatgttcccatgctc agtgaatactgccagatacctctccggcttctgaccaaccactacgagcagaactggaag tactactgccttccttctgggatgatcaactgtggcgtttcctccgaggaagagctcctt ctaaccaagaaactcttctggggaatctttgactccctttctcagaagaaatatgatgct gaccttttcaagatagccacattatgcctgtgtgccatcgctggagccttaccgcctgac tttgtggatactagttttggagcaacactggagaaacaggcaccagtggatgcaaagggc aactttgatcccaaacccatcaacactgccaatatttcccttcctgaaaaacttgagtcc attgccaacaaatatgcagagcattcccatgacaaatggtcctcagataaggtgtcagca ggctggaaacaaggagacagtctggacgatcaggctaaaactcatccactgctgaagcct tacaaagcgctgagtgagaaggagagagaaacgtaccgctggccagtgaaggagtctctg aagagcatgctggctatgggctggaacatcgagcggtccaaggaaggagagtccgtgatc caacaacgagagagtgaaaaacgaaagacccccgactctcagaatgatggattcagtcct gctccaatggatttgaacaatgtcactttgtcaagagagctacagggcatggtggaggtg gttgcagaaaactaccacaacatctggtccaagaagaagaaatctgaacttgttagcaaa ggaggagggagccacccgctgctggttccctatgacaccctgactgctaaagagaagtac agagacagagagaaggcccaggagctcttcaagttcctgcagatcagcggctatgccatc atgagagatcagaaggacgtgggtcaggactcatcatccatggagaagcgttttacatac aagctcctcaaaacgctgctgaagtacgtcgactctgcccaggagttcatcgctcatctg gaggccatggccaccagtgggaagacggacaaatcgcctcatgaccaggaaatcaagttc tttgccaaggtgttgcttcctctgatagatcaaactttcaagaaccactgtctctacttc ctgtccacggccagcaacaacctgagcagctgcggctgtgcctccaacaaagagaaggag atgctcaccagcctgttctgtaagctggcacttcttgtcagacacaggatttctctcttt ggaagtgactctgcaatgatggtgagctgtctgcacatcctctctcaaacagtcgacacc agaacggtgatgaagtccggctcagagttggtcaaagccagcttcaagactttctttgag aacgcggcggaggacctggagaagctggtggagatgctcaagctggggaagttcatgcag tcccgggctcagttgaagagcgtcacgcagagcatcaactacgtgactgtggcgctgctg cccatcctcaccgccctgttcgagcacatcaccacttacgagtttggagtggatctgctc ttgaatgatgtgcagctgtcctgttaccggatcttggccagtttctactgtctgggaacg ggaaagagcgtctttgtggagaagcatcttcctgcgctgggggagagtctggcgacactg gtggccgcgatgcctgtggcgttcctggagcctcaactcaacgctcacaacccaatgtct gtgttcaacaccaagaccccccgagagagagccatcctgagtatgccggacacggtgatg gagatgtgtccggagatgcctcgccttgaaggactgctgaaagacgtcagcgatgtctca gagtccggtgctcgctactccgacatgccacaggtcattgaggtgatccttcccatgctg tgtaactatctgtcatactggtgggagaagggtccggaaaactcctcttcagatgcccag tgctgcactatggtgacctctgaacacctcagcatcatcctggcaaacatcctcaagatc ctcaacaacaacctgggtatcgatgacgccccctggatgaagaggattgcagtctactct cagccaatcatctgcaaggcgggagctcatctgctgagaacccacttcctgcccaccttg gagaaattgaggaacaagacggtgaaggttgtgggtgaagaggagctgctgaaggccgac agtaaaggtgacacccaggaggccgagctgctcatcctggatgagtttgccgtgctctgc agagacctctacgccttctaccccatgctcatccgttacgtggacaacaacaggtccagg tggctgaaggagccggatgcagactccactgagctcttcaggatggtggctgagatcttc atcctctggtgcaagtcccataacttcaaacgtgaggagcaaaactttgtggttcagaat gagatcaacaatctgggcttcctgactggagagggcaaggcgaagatgtccaagtcagga ggcgaccaggagaggaaacacaagcggcgccgcggcgagtattactccgtccagacgtcg ctgatcgtcgcggccctgaagaagctgctgcccatcggcctcaacatgtgcacgcccgga gaccaggagctcatctccctcgccaagatacgctacagtctgaaagaaacagatgacgag gtgaaggaacacttgcgcctgaatttccatctccaggacaagtgtgaagacccggcggtc cagtggcagatgaacctgtacaaagacgtggtggtgaagagcgaggaacccgctaactta gaacacaccgtggaccgagtgcagagcatctcagctgctgtcttccacctggagcaggtg gagcagcctctgaggaataagaagcttgtgtaccataagctgttgtctaaacagcgtaag cgtgctgtggtggcctgtttccggatggctcctctctacaatctacctaggcatcgcgct atcaacttcttcatcccggcctatcagagactttggatagaggcagaggaatactccttt gaggagaagctagttcaggatctggcaaaaaccccgatgaaaattgtggaggaagaggaa gaggaggtggctgaggtccaaccagaccctctccaccaactcatcctccacttcagccac aacgctctgacagagagaagttacttggaagaagaccctttgtatatagcgtatgcagac atgatggcgaagagctgtgcagaggatgatgaggaggaagaagaagaggaagtagaaggg aaagaaaagacttttgaggaaaaagagatggaaaagcagaagatcctgtatcagcagatg aggctgcacgcccgcggggccgcagagatggtgctgcagatgatcagcgccagtaaaggt cgtttgggccccatggtgacctgcaccctcaaactgggaatatccatcttaaatggcggc aatgtgcaagtgcagcagaaaatgctggattacctgaaagagaaaagagatgcaggcttt ttcaagggcctctcaggactgatgcagtcttgcagtgtcttggacttgaatgcatttgag aggcagaacaaagcagaaggacttggcatggtgtcagaagaaggttcaatcaacaatcag cagggttccaaagtgctacaaaatgatgagtttactaaagatctgttccggtttttgcaa cttctttgtgagggccacaatggagatttccagaatttcctgagaacacaaactggaaac acaaccacggtcaacatcatcatcagcaccgttgactatctgctccgtcttcaggaatcg atcagtgacttctactggtactactctggcaaagatgtcatggatgagactggaagacta aacttctccaaagctttatctgttgccaaacagatattcaactcactgactgagtacatt cagggcccgtgtattgggaaccagcagagtttagctcacagcagattgtgggacgcagtt gtgggcttcttgcatgtttttgccaacatgcaaatgaagctttctcaggacgccagtcag attgagctgttgaaggagctgatggatttacagaaggatatggtggtcatgttgctgtct ctgctagagggtaacgtggtgaatggaatgattggaaagcagatggtggacaccctggtg gagtcttccagtaacgtggagatgatcctcaagttcttcgacatgttcctcaaactgaag gacctgacgtcctctgacaccttcaaagagaacgaccctgagtttaagggcattatttca aagaaggagttccagaagtcaatggagtctcagatgcagtacagccagacggagattgag ttcctgctctcgtgcgcggaggccgacgagaatgacatgttcaactacattgactttgtg gagcgtttccacgagccggccaaagatatcggcttcaacgtggcggtgctgctgaccaac ctgtcggaacacatgccgcacgactccagactcgccaccttcttagacctggcggggagc gtactcagctacttcgagccctatctgggtcgtattgaaatcatgggtagcgcaaagcgg atcgagagggtttacttcgagatcagcgagtcgagccgcgagcagtgggagaagccgcag gtcaaagagtccaagcgccagttcatctttgacgtggtcaacgagggcacggagagcgag aagatggagatgtttgtcaatttctgtgaggacaccatttttgagatgcagctggcctcg cagatctccgagccggatgtggtggaacaaccggaggaggaggaagaggacgatgcacac agcctcctggacgagctgggtggagaggaagagggcgccctggagtctgcctcagccttc accaccgcatgccgctcggtcaagaggaagatctccaacgtacgtcaaacattatccgtt aaaaacttctccaagcagttcaagaaaatcaagaagctgagcatcaaggagatcatcacc agcttcttctccttcttctggatgctcttcaccggcttcttcaagggaatctacggactc atcttcgggttcttccacgtcatctggtcctccatgtttggcggtggcctggttgagggg gctaagaacataaaggtgacggacatcctcgggaacatgcccgacccaacccagtttggt atacacggagatgcgattgaaggagagaaagtggaggccatagagtcgtcgggaggttta gagacggccatggcacctgcaggagacacaacagaaatggacagcatgctggagatgctg tccgctcccaagaaggaaggagggaaacatgtggagctcggcctgggtgacttttctgag ctgagcgcagagatctccacttctgaacacaagaagaaagctgctgctaagcctgttgaa gcccccgagaacgaaccggagaaagcagactcagagaaccaggagaaggaggacaagcca aagaaggaggaggtggaggtgaaggagccggtggcggaggagaagcccaaagccaaagcg agtccccccaaagacgcgtctccgtccttcatgctgagcatcttcgcttttctgaaaatc ttcatcaccaagatgctgaacttgctggctcgtaacttctacaacgtgcgtttcctggct ctgtttgtgtgtttcgccatcaacttcattcttctcttctacaaggtcactggtgaagct gaggtagatgaggaggacacctgggacggcgatgaagataatgatgaggagaacacattt ttcgacatggatgagtttgtcctgcaggagagctccggctacatgttacccacgctgcgc ttcctcgctgttttccacaccgtcatctcactcgtctgtctcttcgggtactgcttcctc aaggttcctctggtggtgttcaagagggagaaggagattgcgaggaagcttgaattcgac ggtctctacatcaccgagcagccgtctgacgaggacatcaagggccagtgggatcgactc gtcatcaacaccccgtctttccccagcaactactgggacaagttcatcaagcgcaaggtg atcaataaatatggagacatgtacggagccgagcgcatcgctgagctgttgggcctggat aagagcgctctggactttgaccccactgtggagactgtagagaatgaagcctccctgctc tcctggctgagctccatcgatactaagtaccacatctggaagatgggagtggttctgact gacaattacttcctgtatctgatctggtactccaccatgtccattttcggacacttcaac aacttcttcttcgctgcccatcttctggacatcgccatggtcttcaagtcgctccaaacc atcctgtcttctgtcactcacaacggcaagcagcttatgctgaccgtgggtctgctggcc gtggtcgtctatctctacaccgtggtggccttcaacttcttcaggaagttctacaacggg ggggatgaggacgagcccgacatgaagtgtgacgacatgttgacgtgctacttgttccac atgtacgtgggtgtgagagctggaggcggtatcggcgacgagttggaggacccagctgga gacccctacgagctttaccgcatcatgtttgacatcaccttcttcttcttcgtcatcgtc atcctgctcgccatcattcagggtttgatcattgatgcctttggagagctaagagaccag caggagcaggtgaaggaggacatggagactaagtgcttcatctgtggcatcgggaacgat tactttgaccggacgcctcacgggttcgagacccacaccttacaagaacacaacctcgcg aactacctgttcttcctgatgtacctgatcaacaaggatgagactgaacacacgggtcag gagtcctatgtgtggaagatgtaccaggagagatgctgggacttcttcccgactggagac tgcttcaggaagcagtacgaggaccagctgggttag

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