Thermobacillus composti: Theco_1440
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Entry
Theco_1440 CDS
T02394
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
tco
Thermobacillus composti
Pathway
tco00290
Valine, leucine and isoleucine biosynthesis
tco00620
Pyruvate metabolism
tco01100
Metabolic pathways
tco01110
Biosynthesis of secondary metabolites
tco01210
2-Oxocarboxylic acid metabolism
tco01230
Biosynthesis of amino acids
Module
tco_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
tco00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Theco_1440
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Theco_1440
Enzymes [BR:
tco01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Theco_1440
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
URO-D
Sel1
Motif
Other DBs
NCBI-ProteinID:
AGA57595
UniProt:
L0EEM2
LinkDB
All DBs
Position
complement(1508237..1509850)
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AA seq
537 aa
AA seq
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MKVDISVFDTTLRDGTQGEGISLSAEDKVKIALKLDQLGVHYIEGGNPGSNSKDIEFFRR
MRDMKLNAKITAFGSTRRKNSQADQDTSLVRIVESGVRAATLVGKSWDFHVTTALQTTLE
ENLAMIYDSFAFLKRRGLEAIYDAEHFFDGYKHNPEYALACLRKAAEAGADWIVLCDTNG
GTLPNEIYEIVSRVAKEIDKPIGIHTHNDCELAVANTLAAVQAGARQVQGTINGYGERCG
NANLCSIIPNLQLKMGLRCVSDEQLGQLTSVARYVSEIANAVMPVGQPYVGNAAFAHKGG
IHVSAILKDPKTYEHVQPELVGNQRRILVSELAGQSNIIHKAQEMGLDISSGNERARAVI
EKIKTLEHEGYSFEGADASLELLLRDAFGEQTQIFKLESFKMLVEKSDGRLVSEAIVKID
VDGDIVYTAAEGNGPVNALDNALRKALVQYYPEIMNIALTDYKVRVLDEKDATAAKVRVL
IETTDFKNTWSTVGVSDNVIEASWEALVDSFRYALMNCKKTPAAQEDKREQLGIVNH
NT seq
1614 nt
NT seq
+upstream
nt +downstream
nt
atgaaagtcgatatctccgtatttgacacaacactgcgtgacggcacccagggcgaaggg
atcagcctgtcggcggaagacaaggtgaagatcgccctgaagctggaccaattgggcgtt
cattatatcgaaggcggcaatccgggcagcaacagcaaggacatcgaatttttccgcagg
atgcgggacatgaagctgaacgcgaagattaccgcattcggcagcacgcgccggaagaac
agccaggcggatcaggacacgagcctcgtgcgcatcgtcgaatccggcgtgcgggcggcg
accctggtcggcaagtcgtgggacttccatgtgacgaccgccctgcagacgacgctggaa
gaaaatctcgccatgatttacgattcattcgccttcctcaagcgccggggactggaagcc
atctacgacgccgaacatttcttcgacggctacaaacataatcccgagtatgcgctcgct
tgcctgcggaaggcggccgaagccggcgcggactggatcgtgctgtgcgatacgaacggc
ggcacgctgccgaacgaaatctacgagatcgtctcccgcgtcgcgaaagagatcgacaag
ccgatcggcatccatacgcacaacgactgcgagctcgccgtcgccaacacgctggcggcc
gttcaggcgggcgcccgccaggtgcagggaacaatcaacggctacggtgaacggtgcggc
aacgccaatctgtgctcgatcattccgaatctgcagctcaagatgggcctgcgctgcgtc
tccgacgagcagctcggccagctcacgagcgtcgcccgctatgtcagcgagatcgccaac
gcggtcatgccggtcggccagccgtatgtcggcaacgccgccttcgcgcacaagggcggc
atccacgtctccgccatcctgaaagatccgaaaacctatgagcacgtccagcccgaactc
gtcggcaaccagcggcggattctcgtttccgagctggcgggccagagcaacatcatccac
aaggcgcaggagatgggcctcgacatcagttccggcaacgaacgggcgcgggcggtcatc
gagaaaatcaagacgctcgagcacgaaggctattcgttcgaaggcgccgacgcttcgctc
gaactgctgctgcgcgatgcgttcggcgaacagacgcaaatcttcaagcttgaatcgttc
aagatgctcgtcgagaaatcggacggccggctggtgtccgaagcgatcgtcaagatcgac
gtggacggggacatcgtctacaccgccgcggaaggcaacgggccggtcaacgcgctggac
aacgcgctccggaaagcgcttgtccaatattaccccgagatcatgaacatcgcgctgacc
gactacaaggtccgcgtcctggacgagaaggacgccaccgccgcgaaagtgcgcgtgctg
atcgaaacgaccgatttcaagaacacctggagcaccgtcggcgtgtccgacaacgtcatc
gaagcgagctgggaagcgctcgtcgacagcttccgctacgcgctgatgaactgcaagaaa
acgccggccgcgcaggaggacaaacgcgagcagctcggaatcgtcaatcattga
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