Triplophysa dalaica: 130434371 Help Entry 130434371         CDS       T09616                                  Symbol ryr3 Name (RefSeq) ryanodine receptor 3   KO K04963   ryanodine receptor 3 Organism tdw  Triplophysa dalaica Pathway tdw04020   Calcium signaling pathway tdw04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:tdw00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     130434371 (ryr3)    04020 Calcium signaling pathway     130434371 (ryr3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:tdw04040]     130434371 (ryr3) Ion channels [BR:tdw04040]  Voltage-gated cation channels   Ryanodine receptor    130434371 (ryr3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_8 Ago_Mid EF-hand_1 Motif Other DBs NCBI-GeneID:  130434371 NCBI-ProteinID:  XP_056620483 LinkDB All DBs Position 13:complement(14071385..14156550) Genome browser AA seq 4854 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQCVAAIQKENRKFCLSAEGLGNRLCYLEPTSEAKYFPP DLCICNFVLAQSLSVRALQEMLAGQSGEERFIRRAAQGGGHRTLLYGHAILLRHSFSGMF LTCLKTSRSLTDKLSFDVGLREVSTGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSE RYLHLSMSNGSIQVDASFMQTLWNVQPTCSRANIAVGYLLGGQVMRLFHGHDESLTIPGS DQSAEQQRVVNYETGKGGSKARSLWRLEPLRISWSGSHIRWGQPFRLRHLSTGHYLGQTE DHGLILLDTKKSDTAATAFCFRPSKEKVESGPKRDIDGMGVAEIKYGDSSCFVMHVSTGL WLSYQAPDAKSSRLGPLKRRAVLSLEGHMDDGLILQLCQHEESRAARIIRNTTHLFTQFI RGLDYLTGEKASEVNLPVVEVLQTLNDLIVYFQQPDSELEHEEKQRQLRSIIKRQDLFKE EGMLTLISICIDRLNLYNSAAEFEELAGEEAGEAWKDILNLLYELLAALIRGNRTNCTQL SRKLDWLVSKLERLESSSGILEVLHCILIESPESLNIIQKAHIKSIISLLYKHGRNHKIL DVLCSLCVCNGVAVRANQNFICDHLLPRRDLLLQTRLVNDVQSMRPNIFLGMSEGSAQYK KWYFELIIDQVDHYVTSEPTHLRVGWATTKGYAPYPGGGEGWGGNGVGDDLYSYSFDGLY LWSGRIPRAVASVNQHLLNSDDVVSCCLDLGAPSMSFRINGQPVQGMFEDFNVDGFFFPV VSFSAGVKVRFLLGGRHGDFKFLPPAGYAPCYEALLPKETMRVEPVKEYKRDLEGVRDLL GTTEFLSQASFIPVPVDTSQIVLPPHLENVRDKLAENIHELWGMNKIELGWTYGKVRDDN KRQHPCLVDFSKLPETEKNYNLQMSTETLKTLLTLGCHVAQVNLNAEEDLKRLKLPKNYM MTNGYKPAPLGLSDVRLTPDQEILVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNRRNPR LVPYALLDERTKKSNRDSLREAIRTLIGYGYYIDPPDQETAHKSEVGIESIRLFRVEKTY AVKTGKWYFEFEALTGGDMRVGWARPGCRPDVELGIDDQAFVFDGYRGRRVHMGSHFFGR TWSRGDVVGCMINMEDKSMIFTLNGEIVITNKGSELCFADFETEEGFIPVCSLGLSQIGR MNLGKDASTFKYYTMCGLQEGFEPFAVNMKRDVTMWFSKRLPTFVNVPEDHPHIEVTRID GTVDSPPCLKVTHKTFGTQTSNDDMIFCRLSMPVEFHPGPRKMDINEVIEQRPKDDGGKI DNGIITKYFYSVKIFAGQDPASVWVGWVTPDYHYYSKNFNLSKVRTVTVTLGDERGRVHE SVRRSNCYMVCAGDVATGSTGRSNTDLEIGCFIDLASGLVLFFANGRELPTAYQVEPNSK LFPAVFVQPTSPNLFQFDFPKIPEAMPLSSAIFKSLKRNPEPQCPPRLNVQTIMSVLWSR MPNTFLSVETARVSERHGWVVQCLETLQMMAVHIPEENRCIDIMELSENEDLRQFHYHTL KLFCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLTGQLREGFYDVLISIHLETAKESH LMMKNEFIIPVTEETRSIRLFSDESKCHSLPGVGLSTSITPRLNFTPPCFINTKREQPLF SPQIPLGILKEKAITMLTEAVQGGGNHIRDPVGGSVKYQFVPILKVIGTLLIMDAMTSEE VRTVLLLIDPSVFGDRKEEEEHLALAEQGAEKEEASSNEEKAVEAGEEEGKESKQLPKGL LEKSLPEPVKQQMCELLHFFCDCELKQRIEAIVAFSDDFVSKLQYNQKFRYNELMLALNM SAAVTAKKTREFRSPPQEQINMLLNFSAGDDCTCPEELQDELQGFHDDLRLHCGIPMEEE EEEQDTSLKGRLMAIIYKIKGPPQKTEEPTEKEQAAPTNLKELISQTMVSWAQECKIQDP VLVRSMFSLLRRQYDGVGELLRALRKSYTISTMSVGDAINLLASLGQIRSLLSVRMGEEE GQLMIDGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGGDKNKEIAFPKMVASCCR FLCYFCRISRQNQKAMFDHLSYLLENSSVGLACPTMRGSTPLDVAASSVMDNNSLALALE EPDLEKVVTYLAGCGLQNCPMLIARGYPDIGWNPIEGERYLSFLRFAVFVNGESVEENAN VVVKLLIRRPECFGPALRGEGGQGLLAAMKEAIKISEDPALDLPKLPQGVTPTVGQDEEE EEEVPHMGNSIMSFYSALIDLLGRCAPEMHLINKGKGEALRIRAILRSLVPIKDLVGIIS IPLKIPVVNKDGSVTEPDMNASFCPEHKGPMVLFLDRVYGIDDQSFLLHLLEVGFLPDLR ASASLDSEVLRTTETALAMNRYIGSAVLPLLTRCAHLFAHTEHYAPLIDSTLHTIYRLSK GRSLTKAQRDAIEECLLAICEHLRPSMLQQLLRRLVFDVPQLTEYCQMPIKLLTNHYEQN WKYYCLPTGLGSSGMASEEELHLTKKLFWGLFDALSQKKYDGELFKMAMPCLSAISGAIP PDYVDSSSGSTLVKQASVDAQGNFDPQPINTSNISLAEKLDYIANKYAAHSHEKWSSEKI ALGWTAGDRVDDKAKTHPLLKPYKALSEKERETYRYPVKETLKSMLAMGWNVERTKEGEA MFQQRETEKQRKISESSQGEFKPTPQDLENVILSRELQAMVETVAENYHNIWAKKKKVEL DSKGGGSHPLLVPYDTLTAKEKYRDREKAQELFRFLQINGYAISRGLKDMEQDSSSMEKR IAYKFLKRLLSYVDSAQEFIAHLEAMASSGKTDKSPHDQEIKFFAKILLPLIDQYFKNHC LYLMSSPSINLSSSGYASNKEKEMITSLFCKLAALVRHRISLFGSDSSTMVSCLHILSRS LDFRTVMKSGSELVKAGVRTFFENAAEDLEKTLENLKLGKMGQSRTQMKGVSQIINYTSV ALLPILTVLFQHITQHQFGAELLLDDIQLSCYRILTSLYSLGTGKNIYVEKQLPVLGECL STLVGAMPVAFLEPQLNMHNPQSVFNSKTPRERAILSMPDTVEEMCPEMPELDGLMKDMG EISESGARYTEMPHVIEVILPMLCNYLSYWWSKGPDNTPDDVPCCTTVTSEHLSLILGNI LKILNNNLGIDNAPWMKRLAVYTQPIISKAGADLLRAHFLPTLEKLKKKTVKVVAEEELL RAESRAETQEAELQILDEFAVLCRDLYAFYPMLIRYVDNNRSKWLKKPDSDSTELFKMVS EIFILWCKSHNFKREEQNFVVQNEINNLAFLTSDSKSKMSKSGGQDQERRGKRRKGELYS IQTSLIVAAHKKMLPIGLNMCTPGDQELISLAKIRYSLKDTDEEVKDHLTKHLHLLEKSE DPAVQWQLNLYKDIVVKNEGHPEVQQPVDRIQSISAAVYHLDQVELPLRNKKMVFQKLLS KQRKRAVVACFRMAPLYNLPRHRSINLFLNGYQRLWIETEEYSFEEKLVQDLAKTPMIVV EEEEEEVAEVHPDPLHQLILHFSHNALTERSFLEEDPLYIAYADMMAKSCAENEEEEEEG KEKTFEEKEMEKQKILYQQARLHARGAAEMVLQMISASKCRLGPMVTGTLKLGISILNGG NVLVQQKMLNYLKEKRDAGFFKSLSGLMQSCSVLDLNAFERQNKAESLGMVTEEGSVNSS ERGSKVLQNDEFTKDLFRFLQLLCEGHNNDFQNFLRTQTGNTTTVNIIISTVDYLLRLQE SISDFYWYYSGKDVMDEAGQHNFSKALAVAKQIFNSLTEYIQGPCIGNQQSLANSRLWDA VVGFLHVFANMQMKLSQDSSQIELLKELMDLQKDMVVMLLSLLEGNVVNGTIGKQMVDTL VESSSNVEMILKFFDMFLKLKDLTTSDNFKEYDPDCKGVISKREFHKSMESQKQYTQSEI EFLLSCVEADENDMFHYEEFVERFHEPAKDIGFNVAVLLTNLSEHMPHDSRLSTFLDLAE SVLSYFEPYLGRIEIMGGAKRIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGES EKMELFVNFCEDTIFEMQLASQISEPDAAERPEEDEEEELHSLLDGLSEEDDASLESASA FTAACVSVKKSVSNFRQMLTLKTMRKQFKKFKKLTIREMITGFFSFFWMLFTGFFKGIFG VVFGFFHIIWSSMFGGGLVEGAKNMKVTDILGNMPDPTQFGIHGDVLEAEKIESHELVVS ADMVQMTGTGGEKLEPDVIMDLLNPSGKKEGKHGAEHGLGDVCEILSEASAPVMKTQKVA ANKPESEPEKADTENQEKEDKAKEETTEEKASAKPTPRAKRGSKKDESPAFMASFIAGLE IYKTKMLNYLARNFYNLRFLALFVAFAINFILLFYKVTGDFDDDDDDEGSWSGAEDEGDE DDEGSEYFILQESTGYMAPTLTFLAVFHSVISLLCLIGYYYLKVPLVVFKREKEIARKLE FDGLYITEQPSDDDIKGQWDRLVIATPSFPNNYWDKFVKRKVINKYGDLYGAERIAELLG LDKSALDFDPTEEAVVKEASLLSWLSSIDTKYHIWKMGVVLTDNSFLYLIWYTTMSILGH YNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFY NKSEDEDQPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIVDPAGDPYELYRILFDITFFFF VIVILLAIIQGLIIDAFGELRDQQEQVNEDMETKCFICGIGNDYFDRTPHGFETHTLQEH NLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLG NT seq 14565 nt NT seq  +upstreamnt  +downstreamnt atggccgaaggtggtgaaggggaagatgagattcagttcttacgaactgatgatgaagtg gtgctgcagtgtgtcgccgccatccagaaagagaatcgcaaattctgcctctcagcagaa ggactcggcaaccgcctgtgttatctggagcccacatcagaggcgaagtattttcctcct gacttatgcatctgtaactttgtgctggcgcaatcgctctcggtaagggctttgcaggag atgctagcagggcagagcggtgaagagaggtttataagacgggcagcccagggaggcgga catcggacactgctgtacggtcacgccatcctcctcaggcattccttcagtggaatgttt ctgacgtgtctgaagacttccaggtctttaacagacaagctgtcttttgatgttggccta cgagaagtttcaactggtgaggcttgttggtggacaattcaccccgcatccaagcagagg tcagaaggtgagaaggtccgcattggggatgacctcatcttggtcagtgtgtcctcagag aggtacctgcacctctccatgtctaacggaagcattcaggtggatgcttctttcatgcaa acactgtggaatgttcagcctacctgctccagagctaacatagcagtggggtatctgctt ggtggacaagttatgcgtctgtttcatgggcacgatgagagtctcactataccaggatct gaccaaagtgcagagcaacagagagtggtaaactatgaaactggaaaaggggggtccaag gccaggtctttatggagactggagcctcttcggataagttggagcgggagccacattaga tggggtcagcccttccgtctacgccatctctccaccggtcactacctgggtcagacagaa gatcacggactgatattactggacacaaagaagtctgacacagctgccactgccttctgc tttaggccaagcaaggaaaaggttgagtctggtccaaagcgtgatattgacggcatggga gttgccgagatcaaatacggcgattcctcctgtttcgtcatgcacgtgtccacgggactg tggctctcctaccaggcacctgatgctaaatcctctcgtctgggaccgctgaagagaagg gccgtcctctctctggagggtcatatggatgatgggcttattctgcagctctgtcagcat gaggagtcccgggcggctcgcatcattcggaacaccactcatctcttcactcagttcatc aggggtctggattatttgactggagaaaaggcctcagaggtgaatctgccggtggtggaa gtcctgcagacgctcaatgacctcatcgtttacttccagcagccggattctgagctggag cacgaggagaaacagaggcagctcagatccatcatcaagcgacaagatctttttaaagag gagggaatgctaactctgatctcaatctgcattgatcggctaaacctgtacaacagtgct gctgagtttgaggagttagcaggcgaggaggctggagaggcatggaaagacattctcaac ctcctttatgagcttctggctgctctgatccgaggaaacaggaccaactgcacacagctc tctcgcaagctggattggctagtcagcaagctggagcgattggagtcctcatcaggtatt ttggaggtacttcattgtatcctcatcgagagtccagaatctcttaacatcatccagaag gcccacatcaaatccatcatctcccttctgtacaagcatgggcgcaaccacaagattcta gatgttctttgttccctttgcgtctgcaacggtgtggctgtgagagccaatcagaatttc atctgtgaccacctgcttcccagaagagacctgctgctccaaacgcgattggtcaacgat gttcaaagtatgagacctaacatctttctgggcatgagtgagggctcagcccagtataag aagtggtactttgagctgatcattgatcaagtagaccactatgtgaccagtgagcccacc caccttcgcgtcggctgggccaccaccaaaggctacgccccctatcctgggggtggagag ggttggggaggaaatggtgtgggtgatgacctttactcctacagttttgatgggctttat ctttggtcaggacgaatcccacgagccgtggcctctgtaaaccagcacctgctgaactca gacgatgtggtgagctgctgtctggatctcggagcccccagtatgtctttccgaattaac ggccagccggtgcaaggcatgtttgaagacttcaacgtagatggcttcttctttcctgtc gtcagtttttctgcaggggtcaaggttcgcttcctgttgggtggtcgccacggagacttc aagttcctgcctccagcaggatacgcaccatgttacgaagccctactccctaaagaaacg atgcgcgtggagcctgtcaaggagtataaaagagatcttgaaggagtgagagatcttttg ggcactacagagttcctctctcaggcttcgttcattcctgttcctgttgacaccagtcag atcgtcctgcctccacatctcgaaaacgtgagggacaagttagctgagaacatccacgag ctgtgggggatgaacaaaatagagcttggatggacatacggcaaggttcgagatgacaac aagaggcagcacccttgccttgttgacttttccaaattaccagaaaccgaaaagaattat aacctgcaaatgtcaacagaaacgttgaagactctgcttacattgggctgtcatgttgcc caagtcaacttaaatgctgaagaagatttaaaaagactcaagctccctaagaactacatg atgacaaatggatataaacctgcaccactgggtctttctgatgtgagactgacacctgat caggagattctagttgataaactggctgaaaatgctcataatgtttgggctaaagatcgc atcaaacaaggttggacctatggtatccagcaggatttaaaaaatcggcgtaatccacgg ctggtgccatatgctttattagatgaacgtactaagaaatcgaacagagatagtcttcgg gaggccatccgaactctgattggatacggatattacatagacccaccagatcaagagaca gcacacaaatcagaggttggcattgagtccatccgtctgttccgcgtggagaagacgtat gccgtgaagacaggaaagtggtattttgagtttgaggctttgactggaggtgacatgaga gtgggatgggcccggcctggctgcagacctgatgtggaactgggaatagatgaccaggca tttgtctttgatggctacaggggtcgtcgagtgcatatgggcagtcatttctttggtagg acatggagtagaggagatgtggtggggtgtatgatcaatatggaggacaagtccatgata ttcacgctaaatggagagatcgtgattaccaacaagggttctgagctctgctttgctgat tttgaaaccgaagaagggttcatcccagtatgcagcctaggtctttcccaaattggacgc atgaacttgggaaaggatgctagtacttttaagtattacaccatgtgtggccttcaggag ggctttgaacccttcgccgtcaacatgaaacgagatgtcaccatgtggttcagcaaacgc ctgcctacgtttgttaatgtgccagaggaccatcctcatattgaggttactagaatagat ggcactgtggactctcctccatgtctaaaagtgacccacaagacatttggcacccagacc agcaacgacgacatgatcttctgccgtctgagcatgcccgttgagttccatcctggtcct cggaaaatggatatcaatgaggtgatcgagcaaagaccaaaggacgatggaggaaagatc gataatggcatcattacgaagtacttctactctgtgaaaatatttgccggacaggaccca gcatcagtgtgggtgggctgggtaacaccggactatcattactacagcaaaaactttaac ctcagtaaagttcgaactgtcaccgtcacactgggcgacgaacgtggacgtgttcacgag agtgtgaggagaagtaattgttacatggtgtgtgctggtgatgttgccaccggctccaca ggccgtagtaacactgatctggaaatcggatgcttcatagatctggcctcaggactggtt ttatttttcgctaatggcagagagttacctactgcataccaggtcgaacctaactcaaaa ctattccccgctgtgtttgttcaacccacaagtcccaatctcttccagtttgattttccc aaaatcccagaagccatgccgctgtcttcagccatctttaagagtttaaagaggaaccca gaaccccagtgtcccccacggctgaatgtgcagaccatcatgtctgtgctgtggagcagg atgcccaacaccttcctgtcggtggagaccgcgcgggtgagcgagaggcacggctgggtg gtgcagtgtctggaaactctacagatgatggccgttcatatcccagaggagaacaggtgt atagacatcatggagttgtcagaaaacgaggatctccgccagttccactatcacacatta aagctattctgcgccctgtgcgccctgggcaacacccgtgtagctcacgccctctgcagc catctcgaccaatcgcagctcctgtacaccattgacaaccagtacctgaccggtcagctc cgtgaaggcttctacgacgtcctgatcagtattcacttggagacagctaaagagtcccat ctcatgatgaagaatgagtttatcatccccgtgacggaggagacgcgcagcattcgtctt ttctctgacgaatccaagtgccactctctcccaggagtgggtctgagcacctcgatcact cctcgcctcaactttacccctccgtgcttcattaacaccaaacgtgagcagcctctcttc agcccacagatccctctgggtatcctaaaagagaaagccatcactatgctcacggaagca gtgcagggcggtggtaaccacatacgggatcccgtgggcggaagcgttaagtatcagttc gttccgattctgaaggtgattggcactctgcttatcatggatgccatgaccagtgaggag gtgaggaccgtcctgctcctcatcgaccccagtgtgttcggagacaggaaggaggaggag gaacatttggcgctggcggagcagggagctgaaaaagaggaagccagcagtaatgaagag aaggccgtggaggccggagaagaggagggtaaggaatcgaaacagctccccaaaggtctt ctggagaagagcttgcctgaaccagtcaagcagcagatgtgtgagctactccactttttc tgcgactgtgagttgaagcagcgcattgaggctatcgtggccttctcagatgattttgtg tccaagttgcagtacaatcaaaagtttcgctacaatgagctgatgctagccctcaacatg tcggctgctgtcactgccaagaagactagagagttccgatcaccccctcaagaacagata aacatgctgctaaacttcagtgctggagatgactgcacctgtcccgaggagctgcaagat gagcttcaaggctttcatgatgatctgcggctacattgtggcatccctatggaagaagag gaggaagagcaggacacatctcttaaaggccgtctgatggccatcatatacaagatcaag ggtcctcctcaaaaaacagaagaaccaaccgagaaagaacaagctgctccaacaaatctg aaggagctgatatctcagaccatggtcagctgggcacaggaatgcaaaatccaagaccca gtgctggttcgcagcatgttcagtcttttgaggagacagtacgatggggttggagagctg cttagggctttgaggaagagctacaccatcagtaccatgtctgtaggggacgccatcaac ctgctggcctctctgggccagattcggtcgctgctcagtgtccgcatgggggaagaggag ggccagctcatgattgacggcctgggggacatcatgaacaacaaagtgttttaccagcat ccaaatttgatgcgtgttctgggcatgcacgagaccgtgatggaggtcatggtcaatgtg ctgggaggagacaagaataaggagatcgcctttcccaaaatggtggccagctgttgccgt ttcctctgctacttctgtcgcatcagccgtcagaatcagaaggctatgtttgaccacttg agctacctacttgagaacagcagcgtgggactggcctgcccgaccatgagaggctccaca ccattggatgtggccgcttcctctgtgatggacaataacagccttgctttggcactagaa gaacctgatcttgaaaaggtggtgacatatctagctggctgtgggctgcagaattgcccg atgctcatagccagaggatacccagacattggctggaacccaatagagggagaacgctat ttgtctttcctccgctttgctgtctttgtcaatggtgaaagtgttgaggagaacgctaac gtagttgtgaagctgttaatcagacgcccggagtgctttggacctgctcttagaggagag ggaggacaaggcttgcttgctgccatgaaggaagccattaaaatctcagaagatcctgcc ttagacctgcccaaattacctcagggggtcacacccacggtagggcaagatgaagaggag gaggaggaggtcccacatatgggcaactctattatgtccttctattcagcccttattgat cttctgggccgctgtgcacctgagatgcatcttattaacaaaggcaaaggtgaagcattg cgtatccgtgccattctgcgttctttggtgcccattaaagatttggtcggaatcatcagt attcccctcaaaataccagtcgtgaataaagacggcagcgtaactgagccggacatgaat gctagcttctgtccagagcacaagggacccatggtgcttttcctggaccgtgtctatggt attgatgaccaaagcttcttgctgcacctgctggaggtgggcttcctgccagacctgcga gcatcagcctccttggactcggaggtgctcagaaccacagaaacggcgctggccatgaat agatacataggctccgcagtgcttcctcttttaacgcgctgtgctcatctgttcgctcac acagagcactacgcacctcttattgactctacgctgcacaccatctatcgtctctccaag ggccgctcgctcaccaaggcccagagagatgctattgaggaatgtctgctggccatctgc gagcatctgaggccatcaatgctacagcagctgttgcgtcgtctcgtgtttgatgtccca cagcttacagagtactgccagatgcccattaagcttttgaccaatcactacgagcagaat tggaagtactactgtctgccaacaggcctgggcagctctggtatggcatcagaggaggaa cttcaccttactaagaaactcttctggggactttttgacgctctttctcagaagaaatac gatggtgagcttttcaaaatggccatgccgtgtttgagcgccatatctggggccattccc cccgactacgtagattccagctcaggttctacgttggttaaacaagcctctgttgatgcc caaggcaactttgacccccagccaattaacacgtctaacatctccctggctgaaaaatta gattatatagcaaacaagtacgcagcgcattcccatgagaaatggtcctctgagaagatc gctcttggctggaccgcgggagatagagtagacgacaaagctaaaactcacccgctttta aaaccttacaaagcactgagtgaaaaggaacgggaaacatatcgctatccagtgaaagag actctgaagagcatgttagcgatgggatggaacgttgagaggaccaaagaaggggaagca atgtttcagcaaagagaaaccgaaaaacaacgcaagatatcagagtcttcccagggtgaa tttaaaccaaccccacaggatctggagaatgtcattctgtcaagagaactgcaggcgatg gtcgaaacagtcgcagaaaattaccacaacatttgggcgaagaaaaagaaagttgaactt gacagtaaaggaggtggaagtcatccactgttagtaccttatgacactctgactgctaag gagaagtacagagatagagagaaagcccaggaactcttcaggttccttcagatcaatgga tatgccatcagcagaggtctgaaggacatggagcaagattcatcgtctatggagaagagg attgcctacaagttccttaagaggctcctgagctatgttgattctgcacaggagttcatt gctcatcttgaggctatggccagcagtggaaagactgacaaatctccccacgatcaagag atcaagttctttgcaaagattctgctgcccctcatagaccagtacttcaagaaccactgc ttgtacctcatgtcatcccccagcatcaacctgagcagcagtggttatgcctccaacaaa gagaaggagatgatcacgagtctattctgtaaactggcagctcttgtcagacacaggatt tcactttttggaagtgactcttccaccatggtgagctgcttacacatactgtcccgctca ttggacttcaggactgtgatgaagtccggctccgagctggtgaaggctggtgtcaggaca ttctttgagaacgcagcagaggacctggagaagactctggagaacctgaagctggggaag atgggacagtcccgcactcagatgaagggcgtcagtcagatcatcaactacacgtcagtg gctctgctgcccatcctgacggttctcttccagcatatcacccagcatcagtttggagcc gaactgctgttggatgacattcagctatcctgttatcggatcttgaccagcctctactct ctgggcaccggcaaaaacatttatgtggagaaacagcttccagtgctaggtgaatgtttg tctactttagttggagccatgcctgtggccttcctggaacctcaattgaatatgcacaac ccccaatctgttttcaactccaaaacaccaagagaaagagcaattttaagcatgccagat actgtggaggagatgtgtcctgagatgcccgagctggacggcctaatgaaggacatgggt gagatatcagaatcgggtgcacgatacactgagatgccacatgtcatcgaggtcatccta cccatgctgtgcaactacctgtcatactggtggtcaaaggggccggataacaccccggat gatgttccatgctgcacgacagtcacatctgagcatctcagcctcatccttggcaacatc ctcaagattctaaacaacaatttaggaatcgataacgctccctggatgaaaagactcgca gtttacacccagcctatcattagcaaggctggtgccgatctcctgagggcacacttcctg ccgacgcttgagaagctgaagaaaaagactgtaaaagtggtggctgaggaagagcttctt cgggctgaaagcagagcagagacacaggaagctgaactacagattctggatgagtttgct gttctctgcagggatctgtacgctttctatcctatgctcattagatacgtggacaacaac agatccaaatggctgaagaaaccggattccgattcaactgaacttttcaaaatggtgtcc gagattttcatcctttggtgtaaatcacataactttaaaagggaagagcaaaattttgtg gtgcaaaatgaaatcaacaacctggcgtttctcacttcggacagcaagtctaagatgtca aagtctggaggtcaggaccaagaaagaagaggaaaaaggagaaaaggagagttatactcc atccagacttccctcattgtagcggctcacaagaagatgctgcctattggcctgaacatg tgcactccgggagaccaggagctcatttccctcgccaagatccgttacagtctgaaagac acagatgaggaggtcaaagatcacctgacaaagcacctccatcttctagagaagtcggaa gatccagcggtgcagtggcagttaaacctttacaaagatattgtggtgaagaacgaggga catccagaagtacagcaacctgtggatagaattcaatccatctctgctgccgtctaccac ctcgatcaggtggagctgcccctgaggaacaagaaaatggtgtttcaaaagctactgtca aagcaacgcaagcgtgccgtcgtggcttgtttccgcatggcaccactttacaatttaccc aggcatcgctcaattaatctcttcctcaatggctatcagagactttggatagagacagaa gagtactcttttgaggagaagctagtgcaggacctggcaaaaactcccatgattgtggta gaggaagaggaggaagaggtggctgaagttcaccctgatcctctccatcagctcatcctt cacttcagtcacaatgctctgactgagaggagtttcctagaggaggaccctctgtatatt gcttacgctgatatgatggcaaagagctgtgccgagaatgaagaagaggaagaagagggg aaagaaaaaacgtttgaggaaaaggaaatggagaagcagaagattttgtaccagcaggcc agacttcacgcgcgtggtgctgcggaaatggtcctacagatgatcagtgctagtaaatgt cgacttggtcccatggtgactggtactcttaaactgggcatttctattctgaatggaggc aacgttcttgtacagcagaaaatgctgaattatttgaaagaaaagcgagatgctggattc tttaaaagtttatctggattgatgcagtcttgcagtgtgctggatttgaatgcgtttgaa aggcaaaataaagcagagagtcttggaatggttactgaagagggctcagtcaactcgagt gagcggggttccaaagtgctacaaaatgatgagtttacaaaggatctattcaggtttttg caactcctttgcgagggccacaataatgatttccaaaacttcctccggacccaaacagga aatactactacagtcaacatcatcattagcactgtggactacctcttacgtctacaagaa tccataagcgatttctactggtattactctgggaaagatgtcatggacgaggctggacaa cataacttctctaaagcgttggcagttgccaaacagatctttaactcactcaccgagtac atccagggcccatgtattgggaatcagcagagtttggcaaacagcaggctgtgggatgca gtggtgggattcttgcatgttttcgccaatatgcaaatgaaactatcgcaggattctagt caaatcgagctactaaaggagctgatggatttgcagaaggatatggtggtcatgttgtta tctcttcttgaaggtaatgtggtcaacggaacaatcggcaagcagatggtcgacacttta gtggagtcctccagcaacgtggaaatgatcctgaaattcttcgacatgttcctcaaactg aaggacctaaccacatcagataacttcaaggagtacgacccagactgcaaaggcgtcata tccaaaagggagttccataaatcgatggaaagccaaaagcaatacacgcagtcggagatc gagttcctactgtcctgcgtggaggcggatgagaatgacatgttccactacgaagagttt gtggaacgtttccacgaaccagccaaggacatcggctttaatgtggccgtgctgctcaca aatctttccgagcacatgcctcacgactcacgcctgtccaccttcttagacctggctgaa agtgtgcttagctactttgagccctaccttggccgtatcgagatcatgggtggcgccaaa aggattgaaagggtttactttgagatcagtgagtccagcagaacccagtgggagaagcct caggtcaaagagtctaaacgacagttcatcttcgacgtggtgaatgaaggcggtgagagc gagaagatggagctcttcgtaaacttctgtgaggacaccatctttgagatgcagttggcg tctcagatttccgagccggatgctgccgagcgtcccgaggaggatgaagaagaggagttg cacagtcttctcgacgggttatctgaggaggacgatgcctcgcttgagtctgcctccgcc ttcaccgccgcatgtgtgtctgtgaagaaaagcgtgtctaatttccgtcaaatgctgact ttaaagactatgcgcaaacagttcaagaaattcaagaagctgaccatccgagagatgatt acaggcttcttctctttcttctggatgctcttcactgggttctttaaaggcatttttgga gttgtcttcgggttcttccatattatttggtcgtccatgtttggaggggggcttgtagag ggggctaaaaacatgaaagtgactgatatcttgggtaacatgcctgatcctacacagttt ggaatccatggtgatgttttggaagcagagaagatcgaaagccatgagctggtggtgtcg gcagatatggtacagatgacaggcactggtggggagaagctggagcccgatgtgatcatg gatctcctcaatccgtcaggaaagaaagaggggaaacatggagcagaacatggtctgggt gatgtctgtgagatactttctgaggctagtgctcctgtcatgaaaactcagaaggtagct gcgaacaagcctgaatctgaaccagagaaagcagacactgagaaccaagagaaagaggac aaggctaaagaggaaacaacagaggaaaaagcatctgccaaaccaactccaagagccaaa cgtggctcaaaaaaagatgaatctccagccttcatggccagctttattgcagggcttgaa atctacaaaaccaaaatgctgaattacctggctcgtaacttctacaacctacgttttctg gctctttttgtggcctttgccatcaacttcatcctgctcttctataaggtgactggagac tttgatgatgatgatgatgatgaaggatcctggagtggagcagaagatgaaggtgatgaa gatgatgaaggatcggaatacttcattcttcaggagagcactggttatatggcgcccact ttgactttcttggctgtgtttcactcagtcatctccttgctttgcctcattggttattat tacctaaaggttcctttagttgtttttaagcgtgagaaagagatcgccagaaagctggag tttgatggtttgtatatcaccgagcagccgtctgatgatgatatcaaaggacagtgggat cgtttggttattgcgactccgtcattccctaacaattactgggacaagtttgttaagaga aaggttatcaataaatatggtgacttgtacggagccgagcgcatagctgaacttctgggt ttggataagagcgcactagacttcgaccccactgaagaggctgtggtgaaggaggcatct ctactgtcctggttgagctctattgataccaagtatcacatctggaagatgggagtagtg ctaactgacaattctttcctctatctgatctggtacaccaccatgtctattctgggacat tacaataacttcttcttcgccgctcatttgctggacatcgccatgggcttcaagacctta aggactattttgtcttccgtgactcacaatggcaaacagttggtgttgactgtggggctt ctggcggtcgtggtctatctgtacaccgtggtggccttcaatttcttccgcaagttctac aataagagcgaggatgaggaccagcctgacatgaagtgtgatgatatgatgacttgttac ctgttccacatgtatgttggtgtgagagcaggtggaggcatcggtgatgagatcgtagat ccggccggtgacccctacgagctctaccgcattctgttcgacattactttctttttcttc gtcatcgtcatcctgctggccatcattcagggtttgatcattgacgccttcggagagttg agagaccagcaggagcaggtgaacgaagacatggagacaaaatgcttcatctgtggaatc ggaaatgactacttcgacagaactccgcatggctttgagacccacaccttacaagagcac aatctggccaactacctatttttcttgatgtatctgatcaacaaagatgagactgaacac actggtcaggaatcgtacgtttggaagatgtatcaggaaagatgctgggatttcttccca gccggagactgtttccgtaagcaatatgaggaccagctgggctag

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