Tepidanaerobacter acetatoxydans Re1: TepRe1_1136
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Entry
TepRe1_1136 CDS
T01495
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
tep
Tepidanaerobacter acetatoxydans Re1
Pathway
tep00300
Lysine biosynthesis
tep00550
Peptidoglycan biosynthesis
tep01100
Metabolic pathways
tep01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tep00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
TepRe1_1136
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TepRe1_1136
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
TepRe1_1136
Enzymes [BR:
tep01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
TepRe1_1136
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF2608
Motif
Other DBs
NCBI-ProteinID:
AEE91282
UniProt:
F4LT13
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All DBs
Position
1185587..1186975
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AA seq
462 aa
AA seq
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MKALTIKEVIKYTSGEYLGNQFNIQITGVSTDSRTINKGELFVPLTGPNFDGHDFIERAF
EKGAAAILCDKNKRSKVDNLPIKNIIFVDNPQSALLSLSAYYRRLFDIPFVAITGSVGKT
TTKEMTAEILNMRFKVLKTSGNLNNEIGLPLTIFRLEEGYQVGVVELGMSALGEISRMAS
VVRPKIAVITNIGIAHIEKLGSKQNIARAKMEILEPLGENDLAVLNGDCQELWDARKTIV
PKTVFFGQERGDIKARNIKSNSTNELEFDIYGCYGEMTFKALLPGIHNVNNALAAIAVGF
EMGLTKEEIQQGFLNLKLPEMRLQFKKSYFGADIIDDAYNANPDSMKSALDFLQQYSYGK
KRAVILGDMLELGDLSEKAHFEIGKYAAERADIFIAVGNYAQSFKKGALQGHLDSRYIHT
FLTVKEAVGEIKKLVEDCDIILIKASRGMKMEQITQTLVRGS
NT seq
1389 nt
NT seq
+upstream
nt +downstream
nt
atgaaggcgctaactattaaagaagttattaaatatactagcggggagtatttgggtaat
caattcaacatacaaataacgggggtttctactgactctagaacaatcaataagggagaa
ttatttgttcctttgactggccctaattttgacggtcacgattttatagagcgagccttt
gaaaaaggtgcagctgctattctttgcgataaaaataaaaggagtaaagtcgataattta
ccaattaaaaatattattttcgtagataatccacagtcagctttattgagtctttcggca
tattatcgaaggctcttcgatattccttttgttgcgattacgggtagtgtaggcaaaact
actactaaagagatgactgccgaaatattaaatatgaggtttaaagttttaaagacttcg
ggaaatcttaataacgaaataggtctgccactgactatttttaggctggaggaaggttat
caggttggagtagtagaattagggatgagtgctcttggagagataagccgtatggcaagt
gtggtaagacccaagattgccgttattacgaatataggcattgcacatatagaaaaactt
ggaagcaaacaaaatatagctcgggctaagatggaaatccttgaacctttaggggagaat
gatttagctgttttaaacggtgattgtcaggaattatgggatgcacgaaaaaccattgtc
cctaaaacggtattttttggacaagagcgtggagatataaaagcaaggaatataaaatct
aacagcacaaatgaattagagtttgatatatatggctgctatggcgaaatgacatttaag
gctttattacctggaattcacaatgttaataatgccttagccgctatagccgttggcttt
gaaatgggccttacaaaagaggaaatacagcaggggtttttaaatttaaaattacctgaa
atgagacttcagtttaaaaaatcctattttggagctgacattattgatgatgcatataat
gctaacccagactctatgaaatcagctcttgattttttacagcaatacagctatggcaag
aaacgagctgtaatattaggagatatgctggaactaggggatttatctgaaaaagcccat
tttgaaatcggtaagtatgcggctgaaagggcagatatatttattgctgtaggaaattac
gctcaaagttttaagaagggagctctgcaaggtcacttggacagccgatatattcatacc
tttttaacagttaaagaggcagtcggagaaataaaaaaacttgtcgaagattgtgatata
attttaataaaagcatctagaggtatgaaaatggaacaaattacgcagacattggtcagg
gggtcatga
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