KEGG   Theropithecus gelada (gelada): 112609390
Entry
112609390         CDS       T08041                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
tge  Theropithecus gelada (gelada)
Pathway
tge04010  MAPK signaling pathway
tge04015  Rap1 signaling pathway
tge04218  Cellular senescence
tge04380  Osteoclast differentiation
tge04620  Toll-like receptor signaling pathway
tge04664  Fc epsilon RI signaling pathway
tge04668  TNF signaling pathway
tge04750  Inflammatory mediator regulation of TRP channels
tge04912  GnRH signaling pathway
tge04935  Growth hormone synthesis, secretion and action
tge04936  Alcoholic liver disease
tge05014  Amyotrophic lateral sclerosis
tge05022  Pathways of neurodegeneration - multiple diseases
tge05132  Salmonella infection
tge05135  Yersinia infection
tge05145  Toxoplasmosis
tge05161  Hepatitis B
tge05163  Human cytomegalovirus infection
tge05167  Kaposi sarcoma-associated herpesvirus infection
tge05169  Epstein-Barr virus infection
tge05170  Human immunodeficiency virus 1 infection
tge05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
tge05417  Lipid and atherosclerosis
tge05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:tge00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    112609390 (MAP2K6)
   04015 Rap1 signaling pathway
    112609390 (MAP2K6)
   04668 TNF signaling pathway
    112609390 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    112609390 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    112609390 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    112609390 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    112609390 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    112609390 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    112609390 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    112609390 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    112609390 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    112609390 (MAP2K6)
   05161 Hepatitis B
    112609390 (MAP2K6)
   05163 Human cytomegalovirus infection
    112609390 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    112609390 (MAP2K6)
   05169 Epstein-Barr virus infection
    112609390 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    112609390 (MAP2K6)
   05135 Yersinia infection
    112609390 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    112609390 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    112609390 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    112609390 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    112609390 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    112609390 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    112609390 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tge01001]
    112609390 (MAP2K6)
Enzymes [BR:tge01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     112609390 (MAP2K6)
Protein kinases [BR:tge01001]
 Serine/threonine kinases: STE group
  STE7 family
   112609390 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Haspin_kinase Choline_kinase DUF4344 APH
Other DBs
NCBI-GeneID: 112609390
NCBI-ProteinID: XP_025217836
Ensembl: ENSTGEG00000026582
UniProt: A0A8D2GCW6
LinkDB
Position
16:42826517..42957674
AA seq 334 aa
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKGTDVASFVKLILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaagaagcgaaaccctggccttaaaattccaaaagaagcattt
gaacaacctcagaccagttccacaccacctcgagatttagactccaaggcttgcatttct
attggaaatcagaactttgaggtgaaggcagatgacctggagcctataatggaactggga
cgaggtgcgtacggggtggtggagaagatgcggcacgtgcccagcgggcagatcatggca
gtgaagcggattcgagccacagtaaatagccaggaacagaaaaggctactgatggatttg
gatatttccatgaggacggtggactgtccattcaccgtcaccttttatggcgcactgttt
cgggagggtgatgtgtggatctgcatggagctcatggacacatcactagataaattctac
aaacaagttattgataaaggccagacaattccagaggacatcttagggaaaatagcagtt
tctattgtaaaagcattagaacatttacacagtaagctgtctgtcattcacagagacgtc
aagccttctaatgtactcattaatgctctcggtcaagtgaagatgtgcgattttggaatc
agtggctacttggtggactctgttgctaaaacaattgatgcgggttgcaaaccatacatg
gcccctgaaagaataaacccagagctcaaccagaagggatacagtgtgaagtctgacatt
tggagtctgggcatcacgatgattgagttggccatccttcgatttccctatgattcctgg
ggaactccatttcagcagctcaaacaggtggtagaggagccatcgccacaactcccagca
gacaagttctctgcagagttcgttgactttacctcacagtgcttaaagaagaattccaaa
gaacggcctacatacccagagctaatgcaacatccatttttcaccctacatgaatccaaa
ggaacagatgtggcatcttttgtaaaactgattcttggagactaa

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