KEGG   Talpa occidentalis (Iberian mole): 119232938
Entry
119232938         CDS       T07495                                 
Symbol
GRB2
Name
(RefSeq) growth factor receptor-bound protein 2
  KO
K04364  growth factor receptor-bound protein 2
Organism
tod  Talpa occidentalis (Iberian mole)
Pathway
tod01521  EGFR tyrosine kinase inhibitor resistance
tod01522  Endocrine resistance
tod04010  MAPK signaling pathway
tod04012  ErbB signaling pathway
tod04014  Ras signaling pathway
tod04062  Chemokine signaling pathway
tod04068  FoxO signaling pathway
tod04072  Phospholipase D signaling pathway
tod04150  mTOR signaling pathway
tod04151  PI3K-Akt signaling pathway
tod04380  Osteoclast differentiation
tod04510  Focal adhesion
tod04540  Gap junction
tod04550  Signaling pathways regulating pluripotency of stem cells
tod04630  JAK-STAT signaling pathway
tod04650  Natural killer cell mediated cytotoxicity
tod04660  T cell receptor signaling pathway
tod04662  B cell receptor signaling pathway
tod04664  Fc epsilon RI signaling pathway
tod04714  Thermogenesis
tod04722  Neurotrophin signaling pathway
tod04910  Insulin signaling pathway
tod04912  GnRH signaling pathway
tod04915  Estrogen signaling pathway
tod04917  Prolactin signaling pathway
tod04926  Relaxin signaling pathway
tod04935  Growth hormone synthesis, secretion and action
tod05034  Alcoholism
tod05160  Hepatitis C
tod05161  Hepatitis B
tod05163  Human cytomegalovirus infection
tod05165  Human papillomavirus infection
tod05200  Pathways in cancer
tod05203  Viral carcinogenesis
tod05205  Proteoglycans in cancer
tod05206  MicroRNAs in cancer
tod05207  Chemical carcinogenesis - receptor activation
tod05208  Chemical carcinogenesis - reactive oxygen species
tod05210  Colorectal cancer
tod05211  Renal cell carcinoma
tod05213  Endometrial cancer
tod05214  Glioma
tod05215  Prostate cancer
tod05220  Chronic myeloid leukemia
tod05221  Acute myeloid leukemia
tod05223  Non-small cell lung cancer
tod05224  Breast cancer
tod05225  Hepatocellular carcinoma
tod05226  Gastric cancer
tod05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:tod00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    119232938 (GRB2)
   04012 ErbB signaling pathway
    119232938 (GRB2)
   04014 Ras signaling pathway
    119232938 (GRB2)
   04630 JAK-STAT signaling pathway
    119232938 (GRB2)
   04068 FoxO signaling pathway
    119232938 (GRB2)
   04072 Phospholipase D signaling pathway
    119232938 (GRB2)
   04151 PI3K-Akt signaling pathway
    119232938 (GRB2)
   04150 mTOR signaling pathway
    119232938 (GRB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    119232938 (GRB2)
   04540 Gap junction
    119232938 (GRB2)
   04550 Signaling pathways regulating pluripotency of stem cells
    119232938 (GRB2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    119232938 (GRB2)
   04660 T cell receptor signaling pathway
    119232938 (GRB2)
   04662 B cell receptor signaling pathway
    119232938 (GRB2)
   04664 Fc epsilon RI signaling pathway
    119232938 (GRB2)
   04062 Chemokine signaling pathway
    119232938 (GRB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    119232938 (GRB2)
   04912 GnRH signaling pathway
    119232938 (GRB2)
   04915 Estrogen signaling pathway
    119232938 (GRB2)
   04917 Prolactin signaling pathway
    119232938 (GRB2)
   04926 Relaxin signaling pathway
    119232938 (GRB2)
   04935 Growth hormone synthesis, secretion and action
    119232938 (GRB2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    119232938 (GRB2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    119232938 (GRB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    119232938 (GRB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    119232938 (GRB2)
   05206 MicroRNAs in cancer
    119232938 (GRB2)
   05205 Proteoglycans in cancer
    119232938 (GRB2)
   05207 Chemical carcinogenesis - receptor activation
    119232938 (GRB2)
   05208 Chemical carcinogenesis - reactive oxygen species
    119232938 (GRB2)
   05203 Viral carcinogenesis
    119232938 (GRB2)
   05231 Choline metabolism in cancer
    119232938 (GRB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    119232938 (GRB2)
   05225 Hepatocellular carcinoma
    119232938 (GRB2)
   05226 Gastric cancer
    119232938 (GRB2)
   05214 Glioma
    119232938 (GRB2)
   05221 Acute myeloid leukemia
    119232938 (GRB2)
   05220 Chronic myeloid leukemia
    119232938 (GRB2)
   05211 Renal cell carcinoma
    119232938 (GRB2)
   05215 Prostate cancer
    119232938 (GRB2)
   05213 Endometrial cancer
    119232938 (GRB2)
   05224 Breast cancer
    119232938 (GRB2)
   05223 Non-small cell lung cancer
    119232938 (GRB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    119232938 (GRB2)
   05160 Hepatitis C
    119232938 (GRB2)
   05163 Human cytomegalovirus infection
    119232938 (GRB2)
   05165 Human papillomavirus infection
    119232938 (GRB2)
  09165 Substance dependence
   05034 Alcoholism
    119232938 (GRB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    119232938 (GRB2)
   01522 Endocrine resistance
    119232938 (GRB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:tod04131]
    119232938 (GRB2)
Membrane trafficking [BR:tod04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    119232938 (GRB2)
SSDB
Motif
Pfam: SH3_1 SH3_9 SH3_2 SH2 SH3_10 SH3_3 SH2_2 DUF5093 hSH3 SH3_4
Other DBs
NCBI-GeneID: 119232938
NCBI-ProteinID: XP_037351218
LinkDB
Position
Unknown
AA seq 217 aa
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
NT seq 654 nt   +upstreamnt  +downstreamnt
atggaagccatcgccaaatatgacttcaaagctactgctgacgacgagctgagcttcaaa
agaggggacatcctcaaggttttgaatgaagaatgtgatcagaactggtacaaggcagag
ctcaatgggaaggacggcttcatccccaagaactacatagagatgaagccacacccgtgg
ttttttggcaaaatccccagagccaaggcagaagaaatgctcagcaagcagcggcatgac
ggagcctttctcatccgagagagtgagagtgctcctggggacttctccctgtctgtcaag
tttgggaatgacgtgcagcacttcaaggtgctccgagatggagcgggcaagtacttcctc
tgggtggtgaagttcaattccctgaatgagctggtagattaccacaggtctacgtccgtc
tccagaaaccagcagatattcctccgcgacatagaacaggtgccccagcagcccacgtac
gtccaggccctctttgactttgatccccaagaggatggagagctgggcttccgtcgggga
gacttcatccacgtcatggataattcagaccccaactggtggaaaggggcttgccacggc
cagaccggcatgttcccccgcaactacgtcaccccggtgaaccggaacgtctaa

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