Talpa occidentalis (Iberian mole): 119240609
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Entry
119240609 CDS
T07495
Symbol
HSD11B1L
Name
(RefSeq) hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod00140
Steroid hormone biosynthesis
tod00980
Metabolism of xenobiotics by cytochrome P450
tod01100
Metabolic pathways
tod05204
Chemical carcinogenesis - DNA adducts
Module
tod_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
119240609 (HSD11B1L)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
119240609 (HSD11B1L)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
119240609 (HSD11B1L)
Enzymes [BR:
tod01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
119240609 (HSD11B1L)
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Ortholog
Paralog
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
Motif
Other DBs
NCBI-GeneID:
119240609
NCBI-ProteinID:
XP_037361048
LinkDB
All DBs
Position
Unknown
AA seq
295 aa
AA seq
DB search
MKVLLLTGLGALFFAYYWDDKFDPADHSCSLPASLQGARVLLTGASAGVGEELAYHYARL
GSHLVLTAQREALLQKVVGNCRKLGAPKVFYIAADMASPEVPEHVVQFALDKLGGLDYLV
LNHLGAAPAGPRTRNAQATRWLMQVNFLSYVQLTSLALPSLTDSKGSLVVVSSLLGRVPT
SFSSPYSAAKFALDGFFSSLRRELDVQDVNVAITMCVLGLQDHASATERFRGITRAKAAP
GPKAALAVIRGSATRASRVFYPWRFHLLCLLRSWLPQPRAWFIRQELNSTATAAA
NT seq
888 nt
NT seq
+upstream
nt +downstream
nt
atgaaggtactgctcctcacagggctgggagccctatttttcgcatattactgggatgac
aagttcgacccagctgaccactcctgctcactgccagccagcctccagggagcgcgtgtg
ctgctgacaggagccagtgcaggtgtgggagaggagctggcatatcattacgcacgcctg
ggttcccacctcgtcctcacggcccaaagagaggctctcctacagaaggtggtagggaac
tgccggaagctgggcgctcccaaggtcttctacatcgctgcggacatggcctcccccgag
gtgcccgagcacgtggtgcagtttgcgctggacaaactgggagggctggattacctggtg
ctgaaccacctcggcgccgcgccggcgggcccgcggacccgcaacgcccaggcaacgcgc
tggttaatgcaggtgaacttcctgagttacgtgcaactgacttcattggccctgcccagc
ctgacagacagcaagggctccctggtggtggtgtcctcgctcctaggccgggtgcccacg
tccttctccagcccctactccgcggccaagttcgcgctggacggcttcttcagctccctg
aggcgggaactggacgtgcaggacgtgaatgtggccatcaccatgtgcgtcctgggcctc
caggatcatgcttcagccactgagcgattccggggcatcacgagggccaaggcagctccg
gggcccaaggcagccctggctgtgatccggggcagcgccacacgtgcctccagagtcttc
tacccatggcgttttcacctgctctgccttctccgaagctggttgcctcaaccacgggcc
tggttcatccgccaggagctcaacagcacggccaccgctgctgcctaa
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