Talpa occidentalis (Iberian mole): 119244248
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Entry
119244248 CDS
T07495
Symbol
PDE8A
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod00230
Purine metabolism
tod01100
Metabolic pathways
tod04927
Cortisol synthesis and secretion
tod04934
Cushing syndrome
tod05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
119244248 (PDE8A)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
119244248 (PDE8A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
119244248 (PDE8A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
119244248 (PDE8A)
Enzymes [BR:
tod01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
119244248 (PDE8A)
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Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PAS
PAS_9
PAS_4
PAS_3
Response_reg
SICA_beta
PAS_8
Motif
Other DBs
NCBI-GeneID:
119244248
NCBI-ProteinID:
XP_054550683
LinkDB
All DBs
Position
Unknown
AA seq
763 aa
AA seq
DB search
MRFHPDQLQVLLVFTKEDSQCNGFWRACEKAGFTCTVAKEAQAALACFRDRHHDIVIIDH
RNPRQLDAEALCRSIRSSKFSENTVIVGVVRRTDREEACVLPLLAAGFTRRYVESPSLMA
CYNELRQLELGEVRSQLKLRACNSIFTALDKSQEAIDITSEDNVIQYANPAFETTMGCQS
GELIGKKLAEVPINEKKADLLNTINSYIRIGKEWQGIHYAKRKNGDNVKQNVKIIPVVGQ
GGKIRHYVSIIRMCNGSTKAEKITECVQSDSHTEHTPGKHKDRRKSSLDVKAVGSRASEA
GTPRRHSSIARIHSMTIEAPITKVINIISAAQESSPMPVTEALDRVLEILRTTELYSPQF
GAKEDDPHASDLVGGLVSDGLRRLSGNEHFLSTKNARLAGLQHLAGAVLAPLSPHDDIPP
PIARAMENEGCWDFNIFELETVTHKRPLVYLGLKTFARFRVCEFLNCSEATLRSWLQIIE
TNYHSSNPYHNSTHSADVLHATAYFLCKERIKQTLDPVDEAAALIAATIHDVDHPGRTNS
FLCNAGSPLAVLYNDTAVLESHHAALAFRLTMGDDQCNIFKNMERNEYRALRQGIIDMVL
ATEMTRHFEHVSKFVNSINKPLAALEKDGDTREGQEAVTAMLRTPENRALVRRMLIKCAD
VANPCRPLEQCVEWAARISEEYFAQTDEEKLRGLPVVMPVFDRSTCSIPRSQISFIDYFI
TDMFDAWDAFVDLPDLMRHLDHNFKYWKRLDDMKLRSLRPPPE
NT seq
2292 nt
NT seq
+upstream
nt +downstream
nt
atgagatttcacccagatcaactccaggtacttttagtgtttaccaaggaagacagccag
tgtaacgggttctggagggcgtgtgaaaaggcagggtttacgtgcacggtggccaaggag
gcgcaggctgccctggcctgtttccgggacagacaccacgacatcgtcatcatagaccac
aggaacccccggcagctggacgcggaggcgctgtgcaggtccatcaggtcgtcgaagttc
tcagaaaacaccgtcatcgtcggcgtggtacgcaggaccgatcgagaagaggcctgcgtg
ctgcccctcctggctgccggctttacacggcgctatgtggagagccccagcctcatggcc
tgttacaacgagctgcgccagctggagctcggggaggtgcggtctcagctgaaactcagg
gcctgtaactcgatatttaccgcattagacaaaagccaggaggcgattgacattaccagt
gaagacaacgtgatacagtatgcaaaccctgcgtttgaaaccacaatgggctgtcagtcg
ggtgaactaatagggaagaagttggcagaggtgccgataaatgaaaagaaggccgacttg
ctcaacaccataaactcctacatcaggataggcaaggaatggcagggcattcactatgcc
aagaggaagaacggggataatgtaaagcagaatgtgaagataatacctgtcgtcggacag
ggaggaaaaattagacactatgtgtccattatcagaatgtgcaacggcagcactaaggct
gagaaaataactgaatgtgttcagtctgacagtcacacagagcacacgcccggcaagcac
aaggacaggaggaagagctcgctggacgtcaaggccgttggctctcgagcaagcgaagcc
ggcaccccgcgacgccactcgtccattgcccgcatccactccatgaccatcgaggcgccc
atcaccaaggtgatcaacatcatcagcgcggcccaggagagcagccccatgcccgtgaca
gaggcgctggaccgggtgctggagatcctgaggaccaccgagctgtactccccgcagttc
ggggccaaggaggacgaccctcacgccagtgacctcgtggggggcctcgtgtcggatggg
ttacgaagactgtcggggaacgagcacttcctctcaacgaagaacgcccgcctcgcgggc
ctgcagcacctcgctggcgccgtcctcgccccgctctccccgcacgacgacatcccgcca
cccatcgctcgggccatggaaaacgaggggtgctgggacttcaatatttttgagctggag
accgtcacccataaaaggcctttggtttatcttggcctcaaaacatttgcccggttcaga
gtctgcgaattcctgaactgctcggaggccacgctgaggtcgtggttacaaattatcgaa
acaaactaccattcctccaacccctaccacaactccacccattctgccgacgtgctgcac
gccactgcctactttctctgcaaagagaggataaagcaaactttagaccccgtcgacgag
gccgccgccctcatcgccgccaccatccacgacgtggaccaccccggcaggaccaactcc
ttcctgtgcaacgcgggcagcccgctggccgtgctctacaacgacaccgccgtgctggag
agccaccacgcggccctggccttccggctgaccatgggcgacgaccagtgcaacatcttc
aagaacatggagcggaacgagtaccgggcgctgcgccagggcatcatcgacatggtgctg
gccacggagatgaccaggcacttcgagcacgtcagcaagttcgtcaacagcatcaacaag
cccttggcggcgctggagaaggacggggacacgcgcgaggggcaggaagccgtgaccgcc
atgctcaggacgcccgagaaccgggcactggtcaggcgcatgctgatcaagtgcgccgac
gtggccaacccctgccggcccctggagcagtgcgtcgagtgggccgcccgcatctccgag
gagtacttcgcacagacagacgaggagaagctgcggggcttgcccgtggtgatgcccgtc
ttcgaccgcagcacctgcagcatcccccggtcccagatctccttcatcgactacttcatc
acggacatgttcgatgcctgggacgcctttgtggacctgcccgacctgatgcggcacctg
gaccacaactttaagtactggaagagactggatgacatgaagctgcggagcctccggccg
ccccccgaatag
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